| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | ribosomal protein S6 kinase, 90kDa, polypeptide 4|This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and c-fos. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 8986) |
| External Link | https://ncbi.nlm.nih.gov/gene/8986 |
| Similar Terms | |
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499 genes differentially expressed following the RPS6KA4 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GNAS | GNAS complex locus | 0.0192492 |
| HOPX | HOP homeobox | 0.0172328 |
| PCNA | proliferating cell nuclear antigen | 0.0170783 |
| KRT7 | keratin 7, type II | 0.0163644 |
| KRT14 | keratin 14, type I | 0.0139112 |
| GRB7 | growth factor receptor-bound protein 7 | 0.0138849 |
| S100A8 | S100 calcium binding protein A8 | 0.013869 |
| A2M | alpha-2-macroglobulin | 0.0132682 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.0130248 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0128784 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.0120044 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.0119379 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.0116831 |
| MIA | melanoma inhibitory activity | 0.0115003 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.011374 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.0112175 |
| MCAM | melanoma cell adhesion molecule | 0.0110899 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | 0.0109918 |
| CSTA | cystatin A (stefin A) | 0.0109847 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0109771 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | 0.0107651 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0106678 |
| PRNP | prion protein | 0.0105444 |
| CHRDL1 | chordin-like 1 | 0.0104292 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.0104232 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0102839 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.0102412 |
| TPM2 | tropomyosin 2 (beta) | 0.0101136 |
| EMP1 | epithelial membrane protein 1 | 0.0100819 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0100351 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0100018 |
| TGM2 | transglutaminase 2 | 0.00991239 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00989372 |
| KRT15 | keratin 15, type I | 0.00987279 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | 0.00983488 |
| NRN1 | neuritin 1 | 0.00975876 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00973729 |
| KRT81 | keratin 81, type II | 0.00958332 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.00957869 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00950534 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | 0.00950043 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00945433 |
| TRIM29 | tripartite motif containing 29 | 0.00937686 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00934496 |
| IL1RN | interleukin 1 receptor antagonist | 0.00926061 |
| SYNM | synemin, intermediate filament protein | 0.00925943 |
| APOD | apolipoprotein D | 0.00924783 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | 0.0091214 |
| NDRG4 | NDRG family member 4 | 0.0090686 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.00901372 |
| HEATR1 | HEAT repeat containing 1 | 0.00898541 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.00894262 |
| CYTL1 | cytokine-like 1 | 0.00891726 |
| RGS5 | regulator of G-protein signaling 5 | 0.00877234 |
| JAG1 | jagged 1 | 0.00876046 |
| CD93 | CD93 molecule | 0.00875703 |
| DOCK4 | dedicator of cytokinesis 4 | 0.00870349 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00869635 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.00868026 |
| SLC35G2 | solute carrier family 35, member G2 | 0.00864165 |
| KRT13 | keratin 13, type I | 0.00862171 |
| SPRR3 | small proline-rich protein 3 | 0.00851015 |
| OPHN1 | oligophrenin 1 | 0.00850882 |
| CD200 | CD200 molecule | 0.00845848 |
| GPNMB | glycoprotein (transmembrane) nmb | 0.00845107 |
| S100A9 | S100 calcium binding protein A9 | 0.00843506 |
| DCHS1 | dachsous cadherin-related 1 | 0.00841314 |
| PLAT | plasminogen activator, tissue | 0.00840776 |
| FABP7 | fatty acid binding protein 7, brain | 0.00833952 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 | 0.00830656 |
| LAPTM5 | lysosomal protein transmembrane 5 | 0.00829121 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.00825953 |
| FHL1 | four and a half LIM domains 1 | 0.00825694 |
| C3 | complement component 3 | 0.0081818 |
| E2F2 | E2F transcription factor 2 | 0.00816303 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.00816046 |
| LAMA4 | laminin, alpha 4 | 0.0081349 |
| MEN1 | multiple endocrine neoplasia I | 0.00811223 |
| TUBA1A | tubulin, alpha 1a | 0.00807877 |
| PLN | phospholamban | 0.00802539 |
| MMP7 | matrix metallopeptidase 7 | 0.00801996 |
| TMEM230 | transmembrane protein 230 | 0.00799703 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00797497 |
| ANGPT2 | angiopoietin 2 | 0.00796982 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.00796633 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.00794553 |
| CRYAB | crystallin, alpha B | 0.0078774 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00787189 |
| PODXL | podocalyxin-like | 0.00784278 |
| KRT6A | keratin 6A, type II | 0.00784246 |
| MGP | matrix Gla protein | 0.00784114 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.00782013 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.00780228 |
| SIRPA | signal-regulatory protein alpha | 0.00779527 |
| LPAR6 | lysophosphatidic acid receptor 6 | 0.00770464 |
| RGS4 | regulator of G-protein signaling 4 | 0.00769143 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 | 0.00768832 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.00767892 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00767007 |
| RPL14 | ribosomal protein L14 | 0.0076656 |
| SSPN | sarcospan | 0.00760505 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 | 0.00759112 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.00757417 |
| EDNRB | endothelin receptor type B | 0.00755705 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00755634 |
| TRIM2 | tripartite motif containing 2 | 0.00753276 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.00751576 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.00748817 |
| PWP1 | PWP1 homolog (S. cerevisiae) | 0.00734064 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.00733718 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.00733601 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.00732986 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | 0.00731593 |
| ANXA2P2 | annexin A2 pseudogene 2 | 0.00731456 |
| CAV2 | caveolin 2 | 0.00727919 |
| MYH11 | myosin, heavy chain 11, smooth muscle | 0.00726912 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00726299 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | 0.00725354 |
| GSPT2 | G1 to S phase transition 2 | 0.0072399 |
| MXRA5 | matrix-remodelling associated 5 | 0.00722446 |
| IPW | imprinted in Prader-Willi syndrome (non-protein coding) | 0.00719937 |
| GPX1 | glutathione peroxidase 1 | 0.00719419 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | 0.00717067 |
| S100A10 | S100 calcium binding protein A10 | 0.00715198 |
| DPH5 | diphthamide biosynthesis 5 | 0.00715146 |
| MUC16 | mucin 16, cell surface associated | 0.00713149 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.00710798 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.00710575 |
| ZBED2 | zinc finger, BED-type containing 2 | 0.0071055 |
| RPP40 | ribonuclease P/MRP 40kDa subunit | 0.00710218 |
| CD53 | CD53 molecule | 0.00710215 |
| THBS2 | thrombospondin 2 | 0.00710079 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00705672 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 | 0.00703334 |
| CENPE | centromere protein E, 312kDa | 0.00703266 |
| NOP56 | NOP56 ribonucleoprotein | 0.00701634 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.00701393 |
| SPRR1B | small proline-rich protein 1B | 0.00700909 |
| B4GALT6 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 | 0.00700612 |
| PRKCA | protein kinase C, alpha | 0.00698079 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00697311 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | 0.00696987 |
| FRMD4B | FERM domain containing 4B | 0.00696047 |
| IL1B | interleukin 1, beta | 0.00695744 |
| EHD3 | EH-domain containing 3 | 0.00694181 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.00693231 |
| CHGB | chromogranin B | 0.00689115 |
| SH2B3 | SH2B adaptor protein 3 | 0.0068781 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.00687202 |
| KIAA0355 | KIAA0355 | 0.00686086 |
| SCEL | sciellin | 0.00684632 |
| NME1 | NME/NM23 nucleoside diphosphate kinase 1 | 0.00684409 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.00684323 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00683211 |
| ETV5 | ets variant 5 | 0.00682504 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | 0.00681117 |
| LAMB1 | laminin, beta 1 | 0.00680764 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.00680428 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | 0.00680371 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.0068012 |
| LDB2 | LIM domain binding 2 | 0.00677701 |
| XIC | X chromosome inactivation center | 0.00677427 |
| SFTPB | surfactant protein B | 0.00677226 |
| MFAP5 | microfibrillar associated protein 5 | 0.00675536 |
| TIMP4 | TIMP metallopeptidase inhibitor 4 | 0.00675165 |
| AOC3 | amine oxidase, copper containing 3 | 0.00674219 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | 0.00674172 |
| PNMA8A | PNMA family member 8A | 0.00672696 |
| GMFG | glia maturation factor, gamma | 0.00670949 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | 0.00670146 |
| PRKD1 | protein kinase D1 | 0.00669452 |
| TPM4 | tropomyosin 4 | 0.00669268 |
| KRT23 | keratin 23, type I | 0.00669087 |
| YBX3 | Y box binding protein 3 | 0.00668888 |
| UFM1 | ubiquitin-fold modifier 1 | 0.00666712 |
| RGCC | regulator of cell cycle | 0.00665729 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | 0.00665549 |
| EGR2 | early growth response 2 | 0.00664621 |
| MEOX2 | mesenchyme homeobox 2 | 0.00661476 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.00661098 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00661045 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.00659852 |
| C14ORF132 | chromosome 14 open reading frame 132 | 0.00658698 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.00656765 |
| CD59 | CD59 molecule, complement regulatory protein | 0.00655187 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0065283 |
| DUSP4 | dual specificity phosphatase 4 | 0.00652179 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 | 0.00651262 |
| MMRN1 | multimerin 1 | 0.00649518 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.00649255 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00646201 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00645368 |
| RPL10 | ribosomal protein L10 | 0.00645049 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.00644452 |
| CLEC2B | C-type lectin domain family 2, member B | 0.00643008 |
| PALMD | palmdelphin | 0.00642301 |
| UPK1B | uroplakin 1B | 0.00642281 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00640152 |
| SFTPA2 | surfactant protein A2 | 0.00635325 |
| ZNF83 | zinc finger protein 83 | 0.00635104 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.00634565 |
| FCGBP | Fc fragment of IgG binding protein | 0.00633557 |
| RPS14P3 | ribosomal protein S14 pseudogene 3 | 0.00633448 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.00633403 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.00633104 |
| EPHA3 | EPH receptor A3 | 0.00628066 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.0062731 |
| CD14 | CD14 molecule | 0.00626214 |
| EFNA5 | ephrin-A5 | 0.00625651 |
| DES | desmin | 0.00625422 |
| DSTN | destrin (actin depolymerizing factor) | 0.00624371 |
| ANOS1 | anosmin 1 | 0.00623716 |
| GYPC | glycophorin C (Gerbich blood group) | 0.00623388 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.00618838 |
| RPL36 | ribosomal protein L36 | 0.0061815 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.00617266 |
| CCN2 | cellular communication network factor 2 | 0.00616413 |
| VPREB1 | pre-B lymphocyte 1 | 0.00616223 |
| ZYX | zyxin | 0.00616004 |
| AMZ2 | archaelysin family metallopeptidase 2 | 0.00614348 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 0.00614021 |
| PXDN | peroxidasin | 0.00612952 |
| MKKS | McKusick-Kaufman syndrome | 0.00612052 |
| LAMC2 | laminin, gamma 2 | 0.00611919 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | 0.00610042 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.00609603 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.00609142 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0060833 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00605777 |
| SRGN | serglycin | 0.00605703 |
| MMP10 | matrix metallopeptidase 10 | 0.00605199 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.00604924 |
| FLNA | filamin A, alpha | 0.00604362 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | 0.00604354 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.00604018 |
| YBX1 | Y box binding protein 1 | 0.00603505 |
| KRT6B | keratin 6B, type II | 0.00603374 |
| TRIAP1 | TP53 regulated inhibitor of apoptosis 1 | 0.00602413 |
| NCK1 | NCK adaptor protein 1 | 0.00601476 |
| HBEGF | heparin-binding EGF-like growth factor | 0.00600802 |
| VEGFA | vascular endothelial growth factor A | 0.00600307 |
| LMOD1 | leiomodin 1 (smooth muscle) | 0.00599133 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa | 0.0059746 |
| SNRPB2 | small nuclear ribonucleoprotein polypeptide B | 0.00597435 |
| S100B | S100 calcium binding protein B | 0.00595957 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) | 0.00595118 |
| IDH3B | isocitrate dehydrogenase 3 (NAD+) beta | 0.00593894 |
| MXRA7 | matrix-remodelling associated 7 | 0.00593704 |
| ZNF721 | zinc finger protein 721 | 0.00593108 |
| INAVA | innate immunity activator | 0.00592994 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FGFR3 | fibroblast growth factor receptor 3 | -0.0160302 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0136595 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -0.0126668 |
| CA2 | carbonic anhydrase II | -0.0125774 |
| ARG1 | arginase 1 | -0.012554 |
| HAT1 | histone acetyltransferase 1 | -0.0124788 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.0116948 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.0116402 |
| METTL7A | methyltransferase like 7A | -0.0115031 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | -0.0111223 |
| CLU | clusterin | -0.0106454 |
| ALDOB | aldolase B, fructose-bisphosphate | -0.0105834 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.0103963 |
| BST2 | bone marrow stromal cell antigen 2 | -0.0103941 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | -0.0103623 |
| ABAT | 4-aminobutyrate aminotransferase | -0.0102084 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00989959 |
| C4BPB | complement component 4 binding protein, beta | -0.00986708 |
| TARP | TCR gamma alternate reading frame protein | -0.00981609 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00974198 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.0096783 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00957455 |
| GLUL | glutamate-ammonia ligase | -0.00955498 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00953273 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.0092557 |
| GSTA1 | glutathione S-transferase alpha 1 | -0.00916624 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.00907422 |
| BRD4 | bromodomain containing 4 | -0.00904561 |
| SIRT3 | sirtuin 3 | -0.00895435 |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 | -0.00894922 |
| TFF1 | trefoil factor 1 | -0.00886666 |
| MAP7 | microtubule-associated protein 7 | -0.00877939 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | -0.00872502 |
| MT1M | metallothionein 1M | -0.00871624 |
| GCH1 | GTP cyclohydrolase 1 | -0.00869833 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.00868714 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 | -0.00865241 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | -0.00863003 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | -0.00861273 |
| IRF9 | interferon regulatory factor 9 | -0.00849195 |
| RXRA | retinoid X receptor, alpha | -0.00843567 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00842997 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | -0.0084243 |
| FABP1 | fatty acid binding protein 1, liver | -0.00837805 |
| AOC1 | amine oxidase, copper containing 1 | -0.00821103 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.00819485 |
| PRKCZ | protein kinase C, zeta | -0.00814934 |
| ADCY9 | adenylate cyclase 9 | -0.00814769 |
| ALB | albumin | -0.00810141 |
| CA12 | carbonic anhydrase XII | -0.00805804 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | -0.00802325 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00800244 |
| IL1R1 | interleukin 1 receptor, type I | -0.00799994 |
| TPBG | trophoblast glycoprotein | -0.00796962 |
| SIK3 | SIK family kinase 3 | -0.00796148 |
| SORD | sorbitol dehydrogenase | -0.00795725 |
| TYMP | thymidine phosphorylase | -0.00791785 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00789171 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | -0.00785324 |
| TBL1X | transducin (beta)-like 1X-linked | -0.00778853 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00778286 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.00777951 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.00775848 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic | -0.00771288 |
| EXPH5 | exophilin 5 | -0.00765098 |
| SOCS1 | suppressor of cytokine signaling 1 | -0.00764293 |
| HYOU1 | hypoxia up-regulated 1 | -0.00761707 |
| GOLM1 | golgi membrane protein 1 | -0.00760587 |
| TMEM106C | transmembrane protein 106C | -0.00759361 |
| CYBRD1 | cytochrome b reductase 1 | -0.00757505 |
| STC2 | stanniocalcin 2 | -0.00755389 |
| ARMT1 | acidic residue methyltransferase 1 | -0.00753676 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00751656 |
| AGR2 | anterior gradient 2 | -0.0075159 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | -0.00749811 |
| CGA | glycoprotein hormones, alpha polypeptide | -0.00740004 |
| QPRT | quinolinate phosphoribosyltransferase | -0.00738986 |
| ATG2A | autophagy related 2A | -0.00737802 |
| RAB8A | RAB8A, member RAS oncogene family | -0.00736741 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00735713 |
| CCP110 | centriolar coiled coil protein 110kDa | -0.00734549 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00733888 |
| SELENBP1 | selenium binding protein 1 | -0.00731455 |
| PKP4 | plakophilin 4 | -0.00731325 |
| APOB | apolipoprotein B | -0.00730015 |
| FKBP5 | FK506 binding protein 5 | -0.0072453 |
| ADSL | adenylosuccinate lyase | -0.00723106 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | -0.00719563 |
| DAXX | death-domain associated protein | -0.0071725 |
| ELN | elastin | -0.00715979 |
| GOLIM4 | golgi integral membrane protein 4 | -0.0071552 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | -0.00713627 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00713073 |
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme | -0.00712922 |
| CTSA | cathepsin A | -0.00712195 |
| RTN3 | reticulon 3 | -0.00711349 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | -0.00706621 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.00703688 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.0070179 |
| CPM | carboxypeptidase M | -0.00700692 |
| MACROD1 | MACRO domain containing 1 | -0.00700474 |
| PER3 | period circadian clock 3 | -0.0070016 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 | -0.00697294 |
| IFI30 | interferon, gamma-inducible protein 30 | -0.00696547 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -0.00695362 |
| ADIPOR2 | adiponectin receptor 2 | -0.00695214 |
| KIF20A | kinesin family member 20A | -0.00686032 |
| NDUFS1 | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | -0.00685319 |
| RACGAP1 | Rac GTPase activating protein 1 | -0.00683878 |
| TSPAN5 | tetraspanin 5 | -0.00681657 |
| ERLIN2 | ER lipid raft associated 2 | -0.00679742 |
| NADK | NAD kinase | -0.00678407 |
| NDC80 | NDC80 kinetochore complex component | -0.0067621 |
| MT1F | metallothionein 1F | -0.00676191 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | -0.00674898 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00672693 |
| SHMT2 | serine hydroxymethyltransferase 2 (mitochondrial) | -0.00672322 |
| APOA1 | apolipoprotein A-I | -0.00671144 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | -0.00670497 |
| ABHD3 | abhydrolase domain containing 3 | -0.00670222 |
| HIC2 | hypermethylated in cancer 2 | -0.00670194 |
| MEPCE | methylphosphate capping enzyme | -0.00668195 |
| BCL7B | B-cell CLL/lymphoma 7B | -0.00667711 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -0.00666948 |
| GOT1 | glutamic-oxaloacetic transaminase 1, soluble | -0.00664566 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | -0.0066222 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00660961 |
| CHN2 | chimerin 2 | -0.00660898 |
| NINJ2 | ninjurin 2 | -0.00658337 |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) | -0.00655512 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.00652812 |
| OLFM1 | olfactomedin 1 | -0.00650557 |
| RHOB | ras homolog family member B | -0.0065029 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.00650205 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -0.00649284 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.0064922 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.00649184 |
| PBK | PDZ binding kinase | -0.00647617 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | -0.00646919 |
| RAB20 | RAB20, member RAS oncogene family | -0.00645616 |
| APOC3 | apolipoprotein C-III | -0.00644604 |
| EFHD1 | EF-hand domain family, member D1 | -0.00644432 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -0.00643794 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.00641731 |
| MTMR2 | myotubularin related protein 2 | -0.00640665 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | -0.00639419 |
| FBN1 | fibrillin 1 | -0.00638565 |
| HEPH | hephaestin | -0.0063653 |
| CCNA2 | cyclin A2 | -0.00636442 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00634622 |
| CREB1 | cAMP responsive element binding protein 1 | -0.00633126 |
| TGFB1 | transforming growth factor, beta 1 | -0.00630756 |
| LAMP1 | lysosomal-associated membrane protein 1 | -0.00628969 |
| XK | X-linked Kx blood group | -0.00627779 |
| SDC2 | syndecan 2 | -0.0062776 |
| VNN1 | vanin 1 | -0.00627501 |
| PLIN2 | perilipin 2 | -0.00627488 |
| FAAH | fatty acid amide hydrolase | -0.00626968 |
| AURKAIP1 | aurora kinase A interacting protein 1 | -0.00626713 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | -0.00625714 |
| FAM117A | family with sequence similarity 117, member A | -0.00623918 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | -0.00623833 |
| CPE | carboxypeptidase E | -0.00620434 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | -0.00619746 |
| SLC22A18 | solute carrier family 22, member 18 | -0.0061773 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | -0.00617441 |
| MSH2 | mutS homolog 2 | -0.00615351 |
| IL7R | interleukin 7 receptor | -0.00615138 |
| HMGN3 | high mobility group nucleosomal binding domain 3 | -0.00614592 |
| KIF5B | kinesin family member 5B | -0.00613475 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00613409 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.00612927 |
| DCXR | dicarbonyl/L-xylulose reductase | -0.00611597 |
| IQCE | IQ motif containing E | -0.00610172 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.0060951 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.00609251 |
| DSC1 | desmocollin 1 | -0.00608871 |
| SPC25 | SPC25, NDC80 kinetochore complex component | -0.00607659 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.00607347 |
| CLIC3 | chloride intracellular channel 3 | -0.00607259 |
| NFE2 | nuclear factor, erythroid 2 | -0.00605294 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -0.00604657 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 | -0.00603773 |
| AHSG | alpha-2-HS-glycoprotein | -0.00603612 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 | -0.00601812 |
| EPHB6 | EPH receptor B6 | -0.00600971 |
| AURKA | aurora kinase A | -0.00600007 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00599963 |
| ADD3 | adducin 3 (gamma) | -0.00598605 |
| MGAM | maltase-glucoamylase | -0.00598168 |
| CYCS | cytochrome c, somatic | -0.00597933 |
| KIF1B | kinesin family member 1B | -0.00597352 |
| ENO3 | enolase 3 (beta, muscle) | -0.00596978 |
| SCG5 | secretogranin V | -0.00593239 |
| ORM1 | orosomucoid 1 | -0.00592699 |
| RETREG2 | reticulophagy regulator family member 2 | -0.00592179 |
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 | -0.00591993 |
| INSIG1 | insulin induced gene 1 | -0.00591285 |
| ZCCHC14 | zinc finger, CCHC domain containing 14 | -0.00590816 |
| DBF4 | DBF4 zinc finger | -0.00589893 |
| GAMT | guanidinoacetate N-methyltransferase | -0.00589336 |
| ZNF768 | zinc finger protein 768 | -0.00589254 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.00589154 |
| UBE4B | ubiquitination factor E4B | -0.00587403 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | -0.00586526 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.00582932 |
| POR | P450 (cytochrome) oxidoreductase | -0.00582814 |
| IL32 | interleukin 32 | -0.00581892 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) | -0.00581563 |
| DGS2 | DiGeorge syndrome/velocardiofacial syndrome complex 2 | -0.00581148 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | -0.00580022 |
| CLN3 | ceroid-lipofuscinosis, neuronal 3 | -0.00579869 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.00579576 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.00579465 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.00578722 |
| PRSS8 | protease, serine, 8 | -0.00578612 |
| GMPR | guanosine monophosphate reductase | -0.00577151 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.00575436 |
| HOXC10 | homeobox C10 | -0.00575038 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | -0.00572055 |
| DLX5 | distal-less homeobox 5 | -0.0057201 |
| ABHD14A | abhydrolase domain containing 14A | -0.00569609 |
| STIP1 | stress-induced phosphoprotein 1 | -0.00568883 |
| CCR7 | chemokine (C-C motif) receptor 7 | -0.00568494 |
| ITM2C | integral membrane protein 2C | -0.00567372 |
| SNAP29 | synaptosomal-associated protein, 29kDa | -0.00566391 |
| TSPAN8 | tetraspanin 8 | -0.00566245 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00565119 |
| SDF4 | stromal cell derived factor 4 | -0.00564457 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 | -0.00562933 |
| BCAS1 | breast carcinoma amplified sequence 1 | -0.00562805 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | -0.00561714 |
| CLDN3 | claudin 3 | -0.00561075 |
| PBLD | phenazine biosynthesis-like protein domain containing | -0.00560653 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | -0.00560283 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00560211 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | -0.00559988 |
| CAB39 | calcium binding protein 39 | -0.00559408 |
| MYL5 | myosin, light chain 5, regulatory | -0.00557926 |
| RAB40B | RAB40B, member RAS oncogene family | -0.00557352 |
| CDHR5 | cadherin-related family member 5 | -0.00556901 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | -0.00556835 |
| TTC39A | tetratricopeptide repeat domain 39A | -0.00556744 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00556724 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 | -0.00554458 |
| ACOT7 | acyl-CoA thioesterase 7 | -0.00554454 |
| AURKB | aurora kinase B | -0.00554053 |
| SHTN1 | shootin 1 | -0.00553943 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.00553697 |
