| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | ribosomal protein S6 kinase, 70kDa, polypeptide 1|This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013] (NCBI Entrez Gene Database, 6198) |
| External Link | https://ncbi.nlm.nih.gov/gene/6198 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the RPS6KB1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA1A | heat shock 70kDa protein 1A | 0.0145473 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.0102518 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00926706 |
| XIC | X chromosome inactivation center | 0.00915425 |
| MGLL | monoglyceride lipase | 0.00902549 |
| PERP | PERP, TP53 apoptosis effector | 0.00891133 |
| TFF1 | trefoil factor 1 | 0.00889149 |
| MMP1 | matrix metallopeptidase 1 | 0.00880723 |
| DSP | desmoplakin | 0.00855589 |
| MX1 | MX dynamin-like GTPase 1 | 0.00842137 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00839722 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.00826576 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00800083 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00795365 |
| KLK11 | kallikrein-related peptidase 11 | 0.00756415 |
| RTN2 | reticulon 2 | 0.00748816 |
| TFF3 | trefoil factor 3 (intestinal) | 0.00741824 |
| AOC1 | amine oxidase, copper containing 1 | 0.00735004 |
| ITPKB | inositol-trisphosphate 3-kinase B | 0.00730559 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.00718656 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.00705106 |
| HTRA1 | HtrA serine peptidase 1 | 0.00700042 |
| TXN | thioredoxin | 0.00695729 |
| STC1 | stanniocalcin 1 | 0.00694439 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.00691736 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00691456 |
| KLK10 | kallikrein-related peptidase 10 | 0.00689637 |
| ACKR3 | atypical chemokine receptor 3 | 0.00684996 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 0.00683743 |
| MMP3 | matrix metallopeptidase 3 | 0.00664895 |
| ITM2C | integral membrane protein 2C | 0.00663343 |
| RPS27L | ribosomal protein S27-like | 0.00661403 |
| OLFM4 | olfactomedin 4 | 0.00660931 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.00642568 |
| SH3BP4 | SH3-domain binding protein 4 | 0.00639783 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00638325 |
| CAB39 | calcium binding protein 39 | 0.00630676 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0062722 |
| CLTB | clathrin, light chain B | 0.00621978 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 0.00619452 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.00610819 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00610795 |
| TSPAN1 | tetraspanin 1 | 0.00610236 |
| ITGA6 | integrin, alpha 6 | 0.00606359 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00605033 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.00604685 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | 0.00602637 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.00601229 |
| SATB2 | SATB homeobox 2 | 0.00600087 |
| EMP1 | epithelial membrane protein 1 | 0.00598081 |
| HMG20B | high mobility group 20B | 0.00591497 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.00586065 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.00586021 |
| KRT15 | keratin 15, type I | 0.00584124 |
| MMP12 | matrix metallopeptidase 12 | 0.00580503 |
| LRP4 | low density lipoprotein receptor-related protein 4 | 0.00572563 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.005697 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.00564518 |
| NRCAM | neuronal cell adhesion molecule | 0.00561152 |
| BAG3 | BCL2-associated athanogene 3 | 0.00561032 |
| FBN2 | fibrillin 2 | 0.00559828 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00559496 |
| SH3YL1 | SH3 and SYLF domain containing 1 | 0.00558213 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00557765 |
| THBS4 | thrombospondin 4 | 0.00554371 |
| MAL | mal, T-cell differentiation protein | 0.00552695 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.00552431 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00551547 |
| SNAI2 | snail family zinc finger 2 | 0.00551251 |
| DPP4 | dipeptidyl-peptidase 4 | 0.00549785 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00548497 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.00546397 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.00545315 |
| C8ORF4 | chromosome 8 open reading frame 4 | 0.00544935 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | 0.00543623 |
| PTK2B | protein tyrosine kinase 2 beta | 0.00539587 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00538034 |
| ECM1 | extracellular matrix protein 1 | 0.00537892 |
| IL6ST | interleukin 6 signal transducer | 0.00537191 |
| PYCARD | PYD and CARD domain containing | 0.00536625 |
| VEGFA | vascular endothelial growth factor A | 0.00533699 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.00533462 |
| S100A11 | S100 calcium binding protein A11 | 0.00531595 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | 0.00530992 |
| TOR1A | torsin family 1, member A (torsin A) | 0.00529516 |
| GSTP1 | glutathione S-transferase pi 1 | 0.00528126 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00527496 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | 0.00524023 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00523436 |
| GLOD4 | glyoxalase domain containing 4 | 0.00523077 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00518005 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.00517739 |
| HIST1H2BK | histone cluster 1, H2bk | 0.00515903 |
| GSN | gelsolin | 0.00510474 |
| FAM102A | family with sequence similarity 102, member A | 0.00508993 |
| IL1R2 | interleukin 1 receptor, type II | 0.00508091 |
| PLK2 | polo-like kinase 2 | 0.00506765 |
| DENND1B | DENN/MADD domain containing 1B | 0.0050588 |
| TLE5 | TLE family member 5, transcriptional modulator | 0.00503847 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 0.00502976 |
| KIAA0930 | KIAA0930 | 0.00502481 |
| TSPO | translocator protein (18kDa) | 0.00502303 |
| GRN | granulin | 0.00502039 |
| ADAP1 | ArfGAP with dual PH domains 1 | 0.00500705 |
| LCN2 | lipocalin 2 | 0.00500649 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00500016 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.00496909 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00494563 |
| CTSZ | cathepsin Z | 0.00491292 |
| YPEL5 | yippee-like 5 (Drosophila) | 0.00491115 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 | 0.00489677 |
| CRYL1 | crystallin, lambda 1 | 0.00489044 |
| GPX4 | glutathione peroxidase 4 | 0.00488932 |
| CD9 | CD9 molecule | 0.00486111 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | 0.00484541 |
| MVP | major vault protein | 0.00483672 |
| FOXG1 | forkhead box G1 | 0.00481498 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.00478692 |
| TGFA | transforming growth factor, alpha | 0.00476432 |
| VDAC1 | voltage-dependent anion channel 1 | 0.00476084 |
| FGF1 | fibroblast growth factor 1 (acidic) | 0.00475887 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.0047361 |
| PLXNA1 | plexin A1 | 0.00473233 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00472358 |
| CHGA | chromogranin A | 0.00471672 |
| EDN3 | endothelin 3 | 0.00470944 |
| HSPA2 | heat shock 70kDa protein 2 | 0.00470126 |
| CALD1 | caldesmon 1 | 0.00469898 |
| BPIFA1 | BPI fold containing family A, member 1 | 0.00469431 |
| IPO13 | importin 13 | 0.00468975 |
| FHL2 | four and a half LIM domains 2 | 0.00467763 |
| CNTN1 | contactin 1 | 0.00467543 |
| CAPG | capping protein (actin filament), gelsolin-like | 0.00467444 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.00466713 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | 0.00466681 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.00466423 |
| HIGD2A | HIG1 hypoxia inducible domain family, member 2A | 0.00462317 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00461839 |
| GLUD1 | glutamate dehydrogenase 1 | 0.00457627 |
| CRYAB | crystallin, alpha B | 0.00455718 |
| TRAPPC6A | trafficking protein particle complex 6A | 0.00455132 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.0045501 |
| IL1R1 | interleukin 1 receptor, type I | 0.00454593 |
| AMDHD2 | amidohydrolase domain containing 2 | 0.00453838 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.00452725 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.00451377 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00450964 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00449826 |
| PTCH1 | patched 1 | 0.00448543 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.00448514 |
| SMAD7 | SMAD family member 7 | 0.00447141 |
| WNT5B | wingless-type MMTV integration site family, member 5B | 0.00446247 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00445986 |
| ANXA1 | annexin A1 | 0.00445689 |
| PDLIM4 | PDZ and LIM domain 4 | 0.0044489 |
| JUNB | jun B proto-oncogene | 0.00444592 |
| UBE3C | ubiquitin protein ligase E3C | 0.00444548 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0044408 |
| MAB21L2 | mab-21-like 2 (C. elegans) | 0.00443236 |
| GNG12 | guanine nucleotide binding protein (G protein), gamma 12 | 0.00442656 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | 0.00441295 |
| DBN1 | drebrin 1 | 0.0044079 |
| OPHN1 | oligophrenin 1 | 0.00440676 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.00439006 |
| TP53TG1 | TP53 target 1 (non-protein coding) | 0.00438553 |
| FLNA | filamin A, alpha | 0.00437736 |
| LONP2 | lon peptidase 2, peroxisomal | 0.00436693 |
| HSPB1 | heat shock 27kDa protein 1 | 0.00434994 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 | 0.00433782 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.00433231 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | 0.00432374 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.00432367 |
| LSR | lipolysis stimulated lipoprotein receptor | 0.00431176 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00430012 |
| IRF6 | interferon regulatory factor 6 | 0.0042932 |
| FGFBP1 | fibroblast growth factor binding protein 1 | 0.00428022 |
| PLSCR4 | phospholipid scramblase 4 | 0.00426111 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 0.00425849 |
| COG2 | component of oligomeric golgi complex 2 | 0.00425825 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 | 0.00425776 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00425691 |
| ATP5F1D | ATP synthase F1 subunit delta | 0.0042566 |
| GPX3 | glutathione peroxidase 3 | 0.00425096 |
| CCNG2 | cyclin G2 | 0.00422696 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00421907 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | 0.00421846 |
| PXDC1 | PX domain containing 1 | 0.00421015 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 0.00421013 |
| TBX3 | T-box 3 | 0.00419448 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0041944 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00419212 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.00418935 |
| TPM1 | tropomyosin 1 (alpha) | 0.00417566 |
| SDS | serine dehydratase | 0.0041711 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00416661 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0041533 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00415176 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | 0.00415164 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 0.00414908 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 | 0.00413586 |
| DST | dystonin | 0.00413054 |
| HEBP2 | heme binding protein 2 | 0.00411538 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | 0.00410564 |
| CTSA | cathepsin A | 0.00410148 |
| C9ORF16 | chromosome 9 open reading frame 16 | 0.00409826 |
| IRF7 | interferon regulatory factor 7 | 0.00409721 |
| ABHD2 | abhydrolase domain containing 2 | 0.00409343 |
| COL4A1 | collagen, type IV, alpha 1 | 0.00408107 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | 0.00408006 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | 0.00406611 |
| APOD | apolipoprotein D | 0.00406589 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.00406308 |
| OAZ1 | ornithine decarboxylase antizyme 1 | 0.00406215 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | 0.00406003 |
| TMEM8A | transmembrane protein 8A | 0.00405865 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.00404976 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.00404948 |
| DES | desmin | 0.00403971 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0040248 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.00402323 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00401934 |
| RGS20 | regulator of G-protein signaling 20 | 0.00401762 |
| CAPN3 | calpain 3, (p94) | 0.00401501 |
| COX5B | cytochrome c oxidase subunit Vb | 0.00400548 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.00399918 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated | 0.00399239 |
| MAPK13 | mitogen-activated protein kinase 13 | 0.00399209 |
| LOXL1 | lysyl oxidase-like 1 | 0.00398146 |
| SP110 | SP110 nuclear body protein | 0.00398136 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00397961 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 0.00397613 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 | 0.00397581 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.00396763 |
| PXDN | peroxidasin | 0.00396144 |
| PPP6C | protein phosphatase 6, catalytic subunit | 0.00395565 |
| MFAP2 | microfibrillar-associated protein 2 | 0.00394631 |
| GPR137B | G protein-coupled receptor 137B | 0.00393927 |
| CENPE | centromere protein E, 312kDa | 0.00393751 |
| RALB | v-ral simian leukemia viral oncogene homolog B | 0.00393657 |
| MYO6 | myosin VI | 0.00392347 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | 0.00391346 |
| ANXA4 | annexin A4 | 0.00391228 |
| RIMBP2 | RIMS binding protein 2 | 0.00390943 |
| UQCR11 | ubiquinol-cytochrome c reductase, complex III subunit XI | 0.00389625 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.00389503 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.00389336 |
| CALB1 | calbindin 1, 28kDa | 0.00385971 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.00385876 |
| FSCN1 | fascin actin-bundling protein 1 | 0.00385347 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.00385291 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00902434 |
| NUP85 | nucleoporin 85kDa | -0.00894429 |
| MRPL12 | mitochondrial ribosomal protein L12 | -0.00819733 |
| MAGEA3 | melanoma antigen family A3 | -0.00795768 |
| CCDC47 | coiled-coil domain containing 47 | -0.00762701 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -0.00758237 |
| EREG | epiregulin | -0.00743342 |
| FASN | fatty acid synthase | -0.00709191 |
| CHEK1 | checkpoint kinase 1 | -0.00706319 |
| TSPAN13 | tetraspanin 13 | -0.00705826 |
| JMJD6 | jumonji domain containing 6 | -0.00699841 |
| SIRT3 | sirtuin 3 | -0.00695631 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | -0.00691046 |
| MRPL58 | mitochondrial ribosomal protein L58 | -0.0067352 |
| S100A9 | S100 calcium binding protein A9 | -0.00663389 |
| JPT1 | Jupiter microtubule associated homolog 1 | -0.00645691 |
| S100A8 | S100 calcium binding protein A8 | -0.00643027 |
| CDR2L | cerebellar degeneration-related protein 2-like | -0.00639414 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00634195 |
| MRPS7 | mitochondrial ribosomal protein S7 | -0.0062952 |
| EIF4A3 | eukaryotic translation initiation factor 4A3 | -0.00627189 |
| WT1 | Wilms tumor 1 | -0.00609371 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00607752 |
| FUS | FUS RNA binding protein | -0.00607368 |
| FOLR1 | folate receptor 1 (adult) | -0.00604547 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00602746 |
| SFN | stratifin | -0.00598837 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | -0.0059415 |
| SNX10 | sorting nexin 10 | -0.00592857 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00592746 |
| CLU | clusterin | -0.00591002 |
| CLGN | calmegin | -0.00588675 |
| NARF | nuclear prelamin A recognition factor | -0.00587717 |
| NOL11 | nucleolar protein 11 | -0.00587539 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | -0.00581495 |
| CDC20 | cell division cycle 20 | -0.00580712 |
| H1-0 | H1.0 linker histone | -0.00580097 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00571512 |
| AMZ2 | archaelysin family metallopeptidase 2 | -0.00568942 |
| IL18 | interleukin 18 | -0.00565736 |
| PRPF19 | pre-mRNA processing factor 19 | -0.00564483 |
| HMBS | hydroxymethylbilane synthase | -0.00560063 |
| CHN1 | chimerin 1 | -0.00559161 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | -0.00555473 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00555331 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00552655 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.00549562 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00544075 |
| CYBB | cytochrome b-245, beta polypeptide | -0.00541899 |
| FAM216A | family with sequence similarity 216, member A | -0.00539989 |
| TLK2 | tousled-like kinase 2 | -0.0053748 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | -0.00534092 |
| ODC1 | ornithine decarboxylase 1 | -0.0053335 |
| NME1 | NME/NM23 nucleoside diphosphate kinase 1 | -0.00533235 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.00533197 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.00531559 |
| MCM2 | minichromosome maintenance complex component 2 | -0.00528904 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.00528327 |
| PFAS | phosphoribosylformylglycinamidine synthase | -0.00525493 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00524879 |
| GGA3 | golgi-associated, gamma adaptin ear containing, ARF binding protein 3 | -0.0052072 |
| PRR15L | proline rich 15-like | -0.00519782 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.00516261 |
| MRPS16 | mitochondrial ribosomal protein S16 | -0.00515592 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | -0.00515379 |
| MCAM | melanoma cell adhesion molecule | -0.00515328 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.00514839 |
| HLTF | helicase-like transcription factor | -0.00514151 |
| ACOX1 | acyl-CoA oxidase 1, palmitoyl | -0.00513186 |
| CENPU | centromere protein U | -0.00511907 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | -0.0051171 |
| GANAB | glucosidase, alpha; neutral AB | -0.00510633 |
| PLBD1 | phospholipase B domain containing 1 | -0.00509315 |
| SFTPD | surfactant protein D | -0.00505743 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | -0.00505064 |
| CSNK1D | casein kinase 1, delta | -0.00503995 |
| C1QA | complement component 1, q subcomponent, A chain | -0.00503766 |
| CREB1 | cAMP responsive element binding protein 1 | -0.00502768 |
| MXRA7 | matrix-remodelling associated 7 | -0.00502105 |
| CDC6 | cell division cycle 6 | -0.00501164 |
| EPAS1 | endothelial PAS domain protein 1 | -0.00500719 |
| C1QB | complement component 1, q subcomponent, B chain | -0.00500394 |
| MAST2 | microtubule associated serine/threonine kinase 2 | -0.00500044 |
| BIRC5 | baculoviral IAP repeat containing 5 | -0.00497052 |
| PARP2 | poly (ADP-ribose) polymerase 2 | -0.00496462 |
| XK | X-linked Kx blood group | -0.00493273 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.00490387 |
| GRB2 | growth factor receptor-bound protein 2 | -0.00490304 |
| PDZD2 | PDZ domain containing 2 | -0.00490003 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00488134 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.00487224 |
| TK1 | thymidine kinase 1, soluble | -0.00486838 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00484665 |
| RDX | radixin | -0.00483274 |
| AIF1 | allograft inflammatory factor 1 | -0.0048202 |
| NAT10 | N-acetyltransferase 10 (GCN5-related) | -0.00480478 |
| COL4A6 | collagen, type IV, alpha 6 | -0.00474646 |
| RCAN2 | regulator of calcineurin 2 | -0.00474192 |
| C3 | complement component 3 | -0.00473448 |
| CPE | carboxypeptidase E | -0.004734 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.00472429 |
| NUP107 | nucleoporin 107kDa | -0.0047156 |
| EGR2 | early growth response 2 | -0.00469094 |
| PRMT3 | protein arginine methyltransferase 3 | -0.00469041 |
| CST7 | cystatin F (leukocystatin) | -0.00468144 |
| GSTT1 | glutathione S-transferase theta 1 | -0.00467702 |
| PTK2 | protein tyrosine kinase 2 | -0.00467332 |
| ELOVL6 | ELOVL fatty acid elongase 6 | -0.00466415 |
| FN3KRP | fructosamine 3 kinase related protein | -0.00465989 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -0.00465371 |
| APMAP | adipocyte plasma membrane associated protein | -0.00465227 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | -0.00463768 |
| TIMELESS | timeless circadian clock | -0.00460681 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | -0.00460571 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | -0.00459906 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00459006 |
| GZMH | granzyme H (cathepsin G-like 2, protein h-CCPX) | -0.00458181 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | -0.00457807 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00457647 |
| SAP30BP | SAP30 binding protein | -0.004568 |
| CENPX | centromere protein X | -0.00455232 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | -0.00453918 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.00453386 |
| EXOC7 | exocyst complex component 7 | -0.00451391 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.00450918 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | -0.00448318 |
| NUP88 | nucleoporin 88kDa | -0.00447604 |
| SAP30 | Sin3A-associated protein, 30kDa | -0.00447448 |
| SFTPB | surfactant protein B | -0.00447321 |
| NSF | N-ethylmaleimide-sensitive factor | -0.0044623 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00445201 |
| PTN | pleiotrophin | -0.00443791 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.00442681 |
| SIDT2 | SID1 transmembrane family, member 2 | -0.00442424 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | -0.00441444 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | -0.00440877 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | -0.0044059 |
| CCNA2 | cyclin A2 | -0.00440199 |
| CD8A | CD8a molecule | -0.00440136 |
| CP | ceruloplasmin (ferroxidase) | -0.00438016 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00437901 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) | -0.00437568 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00436717 |
| NMU | neuromedin U | -0.00436361 |
| EDNRA | endothelin receptor type A | -0.00436245 |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like | -0.0043604 |
| OXLD1 | oxidoreductase-like domain containing 1 | -0.00435851 |
| HOXB6 | homeobox B6 | -0.00435831 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 | -0.00435779 |
| ATP7A | ATPase, Cu++ transporting, alpha polypeptide | -0.00435747 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.00435463 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.0043524 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00434094 |
| HOPX | HOP homeobox | -0.00434082 |
| PSMD12 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | -0.00434032 |
| KCTD2 | potassium channel tetramerization domain containing 2 | -0.00433149 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | -0.00433065 |
| TRIM37 | tripartite motif containing 37 | -0.00431242 |
| AIM2 | absent in melanoma 2 | -0.00430559 |
| COIL | coilin | -0.00430282 |
| RPIA | ribose 5-phosphate isomerase A | -0.00429821 |
| FABP7 | fatty acid binding protein 7, brain | -0.00427796 |
| ZWILCH | zwilch kinetochore protein | -0.0042722 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0042656 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | -0.00426418 |
| PCNA | proliferating cell nuclear antigen | -0.00425885 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | -0.00425127 |
| GIMAP6 | GTPase, IMAP family member 6 | -0.00423442 |
| SRPRA | SRP receptor subunit alpha | -0.00422185 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.00422057 |
| TFAM | transcription factor A, mitochondrial | -0.00421592 |
| TTC27 | tetratricopeptide repeat domain 27 | -0.00421449 |
| DPAGT1 | dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) | -0.00421162 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.00419436 |
| RHOH | ras homolog family member H | -0.00419272 |
| B3GNT1 | -0.00418595 | |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -0.00418366 |
| RNF167 | ring finger protein 167 | -0.00417565 |
| CANT1 | calcium activated nucleotidase 1 | -0.00417079 |
| RAD51C | RAD51 paralog C | -0.00416322 |
| CCL4 | chemokine (C-C motif) ligand 4 | -0.00416216 |
| PSMC5 | proteasome (prosome, macropain) 26S subunit, ATPase, 5 | -0.00415918 |
| RHOA | ras homolog family member A | -0.00415607 |
| TSPAN8 | tetraspanin 8 | -0.00414992 |
| DUS1L | dihydrouridine synthase 1-like (S. cerevisiae) | -0.00414068 |
| SEPTIN9 | septin 9 | -0.00413585 |
| FEN1 | flap structure-specific endonuclease 1 | -0.00411461 |
| TLR2 | toll-like receptor 2 | -0.00410689 |
| SMARCE1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 | -0.0041049 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) | -0.00410315 |
| RPN2 | ribophorin II | -0.00409348 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | -0.00407411 |
| MAGEB2 | melanoma antigen family B2 | -0.00407106 |
| PGC | progastricsin (pepsinogen C) | -0.00407037 |
| POP4 | processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) | -0.00405102 |
| ZBTB16 | zinc finger and BTB domain containing 16 | -0.00404762 |
| COPS7A | COP9 signalosome subunit 7A | -0.00403669 |
| TLR1 | toll-like receptor 1 | -0.00403572 |
| GEMIN2 | gem (nuclear organelle) associated protein 2 | -0.00402759 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.00402491 |
| MCM3 | minichromosome maintenance complex component 3 | -0.00401756 |
| DCXR | dicarbonyl/L-xylulose reductase | -0.00401145 |
| ENO1 | enolase 1, (alpha) | -0.00401055 |
| TYMS | thymidylate synthetase | -0.00400215 |
| KANK2 | KN motif and ankyrin repeat domains 2 | -0.00400112 |
| HSPA4L | heat shock 70kDa protein 4-like | -0.00399006 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0039865 |
| TRAPPC4 | trafficking protein particle complex 4 | -0.00398206 |
| RAB40B | RAB40B, member RAS oncogene family | -0.0039757 |
| FGG | fibrinogen gamma chain | -0.00397265 |
| IL2RB | interleukin 2 receptor, beta | -0.00397112 |
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 | -0.0039694 |
| TIPIN | TIMELESS interacting protein | -0.00396707 |
| TUBD1 | tubulin, delta 1 | -0.00396707 |
| MAP7 | microtubule-associated protein 7 | -0.0039514 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0039492 |
| WDR41 | WD repeat domain 41 | -0.00394916 |
| SUPT4H1 | suppressor of Ty 4 homolog 1 (S. cerevisiae) | -0.00394511 |
| CASC3 | cancer susceptibility candidate 3 | -0.0039394 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | -0.00393214 |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | -0.00393063 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.00391675 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0039099 |
| ADSL | adenylosuccinate lyase | -0.00390265 |
| THOC2 | THO complex 2 | -0.003902 |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase | -0.00390146 |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase | -0.0038937 |
| C5AR1 | complement component 5a receptor 1 | -0.00387847 |
| IFT57 | intraflagellar transport 57 | -0.00387453 |
| EFHC1 | EF-hand domain (C-terminal) containing 1 | -0.00386325 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00386247 |
| RGCC | regulator of cell cycle | -0.00385302 |
| MRPL24 | mitochondrial ribosomal protein L24 | -0.00385102 |
| PTRH2 | peptidyl-tRNA hydrolase 2 | -0.00384375 |
| TFR2 | transferrin receptor 2 | -0.00384008 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.00383175 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00381331 |
| SSRP1 | structure specific recognition protein 1 | -0.00380924 |
| CLEC7A | C-type lectin domain family 7, member A | -0.00380355 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.00380354 |
| HMGB2 | high mobility group box 2 | -0.00380296 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.00378649 |
| BAG2 | BCL2-associated athanogene 2 | -0.00378564 |
| OGFOD3 | 2-oxoglutarate and iron-dependent oxygenase domain containing 3 | -0.00378372 |
| PUS3 | pseudouridylate synthase 3 | -0.00376191 |
| IFT46 | intraflagellar transport 46 | -0.00376176 |
| PFN2 | profilin 2 | -0.00375923 |
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | -0.00375801 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.00375504 |
