RT-112 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description Human urinary bladder transitional cell carcinoma established from the transitional cell carcinoma histological grade G2 excised from a female patient with untreated primary urinary bladder carcinoma in 1973. (BRENDA Tissue and Enzyme Source Ontology, BTO_0003724)
Similar Terms
Downloads & Tools

Genes

292 genes with high or low expression in RT-112 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
BLCAP bladder cancer associated protein 2.94091
TACC3 transforming, acidic coiled-coil containing protein 3 2.77716
GKN1 gastrokine 1 2.74963
FSTL4 follistatin-like 4 2.67245
FABP4 fatty acid binding protein 4, adipocyte 2.54809
PFKL phosphofructokinase, liver 2.52236
BCAP31 B-cell receptor-associated protein 31 2.48482
SNCG synuclein, gamma (breast cancer-specific protein 1) 2.36265
UPK1A uroplakin 1A 2.30039
TRAK1 trafficking protein, kinesin binding 1 2.29745
DUSP9 dual specificity phosphatase 9 2.2945
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.27987
USP47 ubiquitin specific peptidase 47 2.26918
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 2.24851
IVL involucrin 2.20712
ALS2CL ALS2 C-terminal like 2.20457
KRT13 keratin 13, type I 2.17967
CLCA4 chloride channel accessory 4 2.17165
DUOX1 dual oxidase 1 2.17047
FER1L4 fer-1-like family member 4, pseudogene (functional) 2.1482
MFSD10 major facilitator superfamily domain containing 10 2.13132
SH3BP1 SH3-domain binding protein 1 2.12862
DTX4 deltex 4, E3 ubiquitin ligase 2.09503
PSPN persephin 2.09487
ADD1 adducin 1 (alpha) 2.09355
MTUS2 microtubule associated tumor suppressor candidate 2 2.07986
CDRT4 CMT1A duplicated region transcript 4 2.07796
FLII flightless I homolog (Drosophila) 2.06739
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.05745
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 2.04743
MPRIP myosin phosphatase Rho interacting protein 2.04604
PGLYRP4 peptidoglycan recognition protein 4 2.03116
RXRA retinoid X receptor, alpha 2.00902
ALDH1L1 aldehyde dehydrogenase 1 family, member L1 1.99212
KRT35 keratin 35, type I 1.98275
CNN2 calponin 2 1.95797
CNGA1 cyclic nucleotide gated channel alpha 1 1.93512
ATF3 activating transcription factor 3 1.92876
RGS12 regulator of G-protein signaling 12 1.92202
SSH3 slingshot protein phosphatase 3 1.91431
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43 1.90648
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) 1.87577
TMPRSS4 transmembrane protease, serine 4 1.86093
MORC3 MORC family CW-type zinc finger 3 1.85608
PDXK pyridoxal (pyridoxine, vitamin B6) kinase 1.83593
EPHB6 EPH receptor B6 1.83589
BCAT2 branched chain amino-acid transaminase 2, mitochondrial 1.83477
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 1.83458
PDYN prodynorphin 1.82778
ZNF750 zinc finger protein 750 1.82163
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 1.81547
SRSF6 serine/arginine-rich splicing factor 6 1.79853
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.78606
SDC1 syndecan 1 1.77951
CFH complement factor H 1.77703
SEPT8 septin 8 1.77327
PREP prolyl endopeptidase 1.76103
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1 1.75717
TUBG2 tubulin, gamma 2 1.75315
RIPK4 receptor-interacting serine-threonine kinase 4 1.7469
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 1.7397
STXBP2 syntaxin binding protein 2 1.73699
LPCAT4 lysophosphatidylcholine acyltransferase 4 1.73465
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 1.73374
PEMT phosphatidylethanolamine N-methyltransferase 1.73166
TIAM1 T-cell lymphoma invasion and metastasis 1 1.73162
ALOX5 arachidonate 5-lipoxygenase 1.7282
ZNF552 zinc finger protein 552 1.7225
MMP28 matrix metallopeptidase 28 1.72218
PIGP phosphatidylinositol glycan anchor biosynthesis, class P 1.71142
VILL villin-like 1.69973
IL20RA interleukin 20 receptor, alpha 1.69601
GPD1L glycerol-3-phosphate dehydrogenase 1-like 1.69343
CTSH cathepsin H 1.68618
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 1.68454
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.67802
LYPD3 LY6/PLAUR domain containing 3 1.67501
PCGF3 polycomb group ring finger 3 1.66208
MMP12 matrix metallopeptidase 12 1.66165
MYH1 myosin, heavy chain 1, skeletal muscle, adult 1.65781
SRF serum response factor (c-fos serum response element-binding transcription factor) 1.65191
ZNF219 zinc finger protein 219 1.65172
LY6D lymphocyte antigen 6 complex, locus D 1.64968
GORASP1 golgi reassembly stacking protein 1, 65kDa 1.64844
UPK1B uroplakin 1B 1.64766
CFHR2 complement factor H-related 2 1.64565
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 1.63785
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 1.63392
SETD4 SET domain containing 4 1.63391
SUMO3 small ubiquitin-like modifier 3 1.6175
ASCC2 activating signal cointegrator 1 complex subunit 2 1.61175
MMRN2 multimerin 2 1.61048
REPS1 RALBP1 associated Eps domain containing 1 1.6042
MECOM MDS1 and EVI1 complex locus 1.6041
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 1.60291
SIM2 single-minded family bHLH transcription factor 2 1.60258
PLXNA1 plexin A1 1.60189
LGMN legumain 1.59726
GBX2 gastrulation brain homeobox 2 1.58365
SUN2 Sad1 and UNC84 domain containing 2 1.58113
S100A9 S100 calcium binding protein A9 1.57539
MAOA monoamine oxidase A 1.57162
MPZL2 myelin protein zero-like 2 1.56748
KIAA0556 KIAA0556 1.56579
EPHA1 EPH receptor A1 1.56504
HOXD12 homeobox D12 1.56404
GBP2 guanylate binding protein 2, interferon-inducible 1.56372
KLHL29 kelch-like family member 29 1.56299
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 1.56035
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 1.54759
SLC41A3 solute carrier family 41, member 3 1.54641
MVK mevalonate kinase 1.5462
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1 1.54162
AADAC arylacetamide deacetylase 1.54088
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 1.54054
EVPL envoplakin 1.53988
SRPX2 sushi-repeat containing protein, X-linked 2 1.53935
ASIC3 acid sensing (proton gated) ion channel 3 1.53607
SIK1 salt-inducible kinase 1 1.52374
PCDH1 protocadherin 1 1.52012
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 1.51986
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2 1.51887
KIR3DX1 killer cell immunoglobulin-like receptor, three domains, X1 1.51856
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) 1.51754
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 1.51465
SKIL SKI-like proto-oncogene 1.51271
HCAR3 hydroxycarboxylic acid receptor 3 1.50929
MMP1 matrix metallopeptidase 1 1.50889
TRIM29 tripartite motif containing 29 1.50852
ITGB4 integrin, beta 4 1.50756
NDRG2 NDRG family member 2 1.50419
FGFR3 fibroblast growth factor receptor 3 1.50288
MMP10 matrix metallopeptidase 10 1.50275
ULK4 unc-51 like kinase 4 1.50269
EPN2 epsin 2 1.50112
PCNT pericentrin 1.49846
DOT1L DOT1-like histone H3K79 methyltransferase 1.49732
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 1.49639
VIPR1 vasoactive intestinal peptide receptor 1 1.49552
MTMR8 myotubularin related protein 8 1.49277
FLRT3 fibronectin leucine rich transmembrane protein 3 1.49181
WWP1 WW domain containing E3 ubiquitin protein ligase 1 1.48833
KRT4 keratin 4, type II 1.48732
COG7 component of oligomeric golgi complex 7 1.47722
BAIAP3 BAI1-associated protein 3 1.4705
TP53TG1 TP53 target 1 (non-protein coding) 1.46897
DHRS3 dehydrogenase/reductase (SDR family) member 3 1.46706
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.46604
DLK2 delta-like 2 homolog (Drosophila) 1.46414
EFCAB14 EF-hand calcium binding domain 14 1.46179
CHIT1 chitinase 1 (chitotriosidase) 1.46103
ADCY6 adenylate cyclase 6 1.45641
MAPK7 mitogen-activated protein kinase 7 1.45548
MAP2K7 mitogen-activated protein kinase kinase 7 1.45342
CBX7 chromobox homolog 7 1.45182
CTNNBIP1 catenin, beta interacting protein 1 1.45044
LRRC48 leucine rich repeat containing 48 1.44998
ADCK4 aarF domain containing kinase 4 1.44576
KRT23 keratin 23, type I 1.44528
FBLN1 fibulin 1 1.43843
FLJ13224 uncharacterized LOC79857 1.43408
SREBF1 sterol regulatory element binding transcription factor 1 1.42716
ACAA1 acetyl-CoA acyltransferase 1 1.42664
POU2F3 POU class 2 homeobox 3 1.42414
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 1.42213
PIGG phosphatidylinositol glycan anchor biosynthesis, class G 1.4212
F5 coagulation factor V (proaccelerin, labile factor) 1.41779

low expression

Symbol Name Standardized Value
GAR1 GAR1 ribonucleoprotein -2.96793
LSM1 LSM1, U6 small nuclear RNA associated -2.74383
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 -2.68122
SLC25A51 solute carrier family 25, member 51 -2.60116
VIM vimentin -2.58599
SAA4 serum amyloid A4, constitutive -2.57255
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 -2.48487
BTN2A2 butyrophilin, subfamily 2, member A2 -2.39894
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 -2.38538
PARP6 poly (ADP-ribose) polymerase family, member 6 -2.35202
ATXN7 ataxin 7 -2.28826
PSIP1 PC4 and SFRS1 interacting protein 1 -2.28152
EIF4E eukaryotic translation initiation factor 4E -2.26664
TMEM177 transmembrane protein 177 -2.23066
FGL1 fibrinogen-like 1 -2.22944
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit -2.22479
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 -2.18194
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -2.17031
ZMAT3 zinc finger, matrin-type 3 -2.16576
CDK6 cyclin-dependent kinase 6 -2.15432
CREM cAMP responsive element modulator -2.10007
ENPEP glutamyl aminopeptidase (aminopeptidase A) -2.08789
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 -2.04894
FER fer (fps/fes related) tyrosine kinase -2.0397
PGM1 phosphoglucomutase 1 -2.03778
TUBA3C tubulin, alpha 3c -2.03279
ANKRD17 ankyrin repeat domain 17 -2.01942
TGM2 transglutaminase 2 -2.00997
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) -1.99923
SRP72 signal recognition particle 72kDa -1.98942
NLRX1 NLR family member X1 -1.97208
RGS14 regulator of G-protein signaling 14 -1.97193
COL3A1 collagen, type III, alpha 1 -1.96724
HIST1H2BH histone cluster 1, H2bh -1.92066
MGC2889 uncharacterized protein MGC2889 -1.91328
SALL2 spalt-like transcription factor 2 -1.88741
NUP98 nucleoporin 98kDa -1.86865
FUT2 fucosyltransferase 2 (secretor status included) -1.85934
HIST1H2AG histone cluster 1, H2ag -1.85901
ALB albumin -1.83772
GRSF1 G-rich RNA sequence binding factor 1 -1.83278
LRRC15 leucine rich repeat containing 15 -1.83254
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -1.82769
GALC galactosylceramidase -1.80798
IRF7 interferon regulatory factor 7 -1.78572
KIF1A kinesin family member 1A -1.77446
COL9A2 collagen, type IX, alpha 2 -1.76716
HRK harakiri, BCL2 interacting protein -1.73926
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 -1.73864
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 -1.72945
ERCC4 excision repair cross-complementation group 4 -1.72521
NOAZFP nucleolar atypical zinc finger -1.7223
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 -1.7162
PAQR3 progestin and adipoQ receptor family member III -1.71005
NEUROD4 neuronal differentiation 4 -1.70842
SNX15 sorting nexin 15 -1.70499
ACAA2 acetyl-CoA acyltransferase 2 -1.70373
COPS4 COP9 signalosome subunit 4 -1.6848
PLIN2 perilipin 2 -1.67638
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled -1.67454
SLC39A14 solute carrier family 39 (zinc transporter), member 14 -1.65931
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 -1.65564
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast) -1.65173
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 -1.65112
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa -1.64436
ZNF281 zinc finger protein 281 -1.63795
RASSF4 Ras association (RalGDS/AF-6) domain family member 4 -1.63328
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase -1.62977
CASD1 CAS1 domain containing 1 -1.6278
SAP30 Sin3A-associated protein, 30kDa -1.6271
AFF4 AF4/FMR2 family, member 4 -1.62516
EMC6 ER membrane protein complex subunit 6 -1.62196
SYNC syncoilin, intermediate filament protein -1.61633
STAG3 stromal antigen 3 -1.61548
MSN moesin -1.61397
EIF5A2 eukaryotic translation initiation factor 5A2 -1.61188
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B -1.6105
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle -1.60688
SALL1 spalt-like transcription factor 1 -1.60326
PRKACG protein kinase, cAMP-dependent, catalytic, gamma -1.60254
WRN Werner syndrome, RecQ helicase-like -1.60212
VWA5A von Willebrand factor A domain containing 5A -1.60169
NRXN1 neurexin 1 -1.59751
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) -1.59039
HIST1H2BD histone cluster 1, H2bd -1.58942
APOE apolipoprotein E -1.58941
INTS12 integrator complex subunit 12 -1.58776
AIM1L absent in melanoma 1-like -1.58228
UBE2D3 ubiquitin-conjugating enzyme E2D 3 -1.57457
ELN elastin -1.57284
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -1.56033
IP6K1 inositol hexakisphosphate kinase 1 -1.56011
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 -1.55863
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa -1.55343
USP32 ubiquitin specific peptidase 32 -1.54865
TMEM144 transmembrane protein 144 -1.53887
ZFHX4 zinc finger homeobox 4 -1.53375
LEPROTL1 leptin receptor overlapping transcript-like 1 -1.52972
KPNA4 karyopherin alpha 4 (importin alpha 3) -1.52915
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase -1.52878
GLRX glutaredoxin (thioltransferase) -1.52561
BAG2 BCL2-associated athanogene 2 -1.52366
CCDC51 coiled-coil domain containing 51 -1.52231
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 -1.52083
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like -1.49811
MRPS30 mitochondrial ribosomal protein S30 -1.4975
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 -1.49744
ELAC2 elaC ribonuclease Z 2 -1.48553
RUNX3 runt-related transcription factor 3 -1.48282
HIST1H2BG histone cluster 1, H2bg -1.47666
ANXA6 annexin A6 -1.47081
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial -1.45999
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 -1.45823
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 -1.45753
ZC3H13 zinc finger CCCH-type containing 13 -1.45458
PGK2 phosphoglycerate kinase 2 -1.45264
AGTPBP1 ATP/GTP binding protein 1 -1.44897
TWF2 twinfilin actin binding protein 2 -1.44786
RBM28 RNA binding motif protein 28 -1.44389
RANGRF RAN guanine nucleotide release factor -1.44175
H2AFZ H2A histone family, member Z -1.43398
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 -1.43045
TUBB6 tubulin, beta 6 class V -1.42446
BDNF brain-derived neurotrophic factor -1.42391
TRIM3 tripartite motif containing 3 -1.42025