RTI-55 Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
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Genes

10 genes differentially expressed following the RTI-55 small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 4.04319
ADGRE5 adhesion G protein-coupled receptor E5 3.84929
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 3.59004
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 3.28842
PLEKHA8P1 pleckstrin homology domain containing, family A member 8 pseudogene 1 3.02811

decreased expression

Symbol Name Standardized Value
ARPP19 cAMP-regulated phosphoprotein, 19kDa -3.86817
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 -3.81927
ACAT2 acetyl-CoA acetyltransferase 2 -3.49463
RNH1 ribonuclease/angiogenin inhibitor 1 -3.28242
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.25775