RTKN2 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description rhotekin 2| (NCBI Entrez Gene Database, 219790)
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Genes

336 genes differentially expressed following the RTKN2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
LIPH lipase, member H 3.196
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 3.196
TRPV5 transient receptor potential cation channel, subfamily V, member 5 3.196
ERICH6B glutamate-rich 6B 3.196
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 3.196
PRAP1 proline-rich acidic protein 1 3.196
PLA2G4E phospholipase A2, group IVE 3.196
ECM1 extracellular matrix protein 1 3.196
PCDHB11 protocadherin beta 11 3.196
GABRR3 gamma-aminobutyric acid (GABA) A receptor, rho 3 (gene/pseudogene) 3.196
RSPH6A radial spoke head 6 homolog A (Chlamydomonas) 3.196
P2RY8 purinergic receptor P2Y, G-protein coupled, 8 3.196
BTLA B and T lymphocyte associated 3.196
CCDC87 coiled-coil domain containing 87 3.196
CARMIL3 capping protein regulator and myosin 1 linker 3 3.196
ARMH2 armadillo like helical domain containing 2 3.196
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 3.196
CAPS calcyphosine 3.196
NPPA natriuretic peptide A 3.196
ATOH1 atonal homolog 1 (Drosophila) 3.196
PRDM12 PR domain containing 12 3.15073
NANOS3 nanos homolog 3 (Drosophila) 3.15073
LDHC lactate dehydrogenase C 3.15073
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 3.15073
CELF3 CUGBP, Elav-like family member 3 3.15073
PRR22 proline rich 22 3.15073
IL5 interleukin 5 3.15073
GPR22 G protein-coupled receptor 22 3.15073
IGFL3 IGF-like family member 3 3.15073
RXFP2 relaxin/insulin-like family peptide receptor 2 3.15073
FBXL8 F-box and leucine-rich repeat protein 8 3.15073
SLC26A1 solute carrier family 26 (anion exchanger), member 1 3.15073
TMEM176A transmembrane protein 176A 3.15073
FGL2 fibrinogen-like 2 3.15073
CX3CR1 chemokine (C-X3-C motif) receptor 1 3.15073
SCNN1G sodium channel, non voltage gated 1 gamma subunit 3.15073
EDDM3B epididymal protein 3B 3.15073
NLRP10 NLR family, pyrin domain containing 10 3.15073
GNAT3 guanine nucleotide binding protein, alpha transducing 3 3.15073
MUC22 mucin 22 3.15073
TRPV6 transient receptor potential cation channel, subfamily V, member 6 3.15073
SPRR1B small proline-rich protein 1B 3.15073
C11ORF87 chromosome 11 open reading frame 87 3.15073
GIMAP5 GTPase, IMAP family member 5 3.15073
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit 3.15073
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 3.15073
PCDHGB3 protocadherin gamma subfamily B, 3 3.15073
KRTAP21-1 keratin associated protein 21-1 3.15073
DCAF4L1 DDB1 and CUL4 associated factor 4-like 1 3.15073
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 3.15073
ACKR5 atypical chemokine receptor 5 3.15073
TMIGD1 transmembrane and immunoglobulin domain containing 1 3.15073
FRG2C FSHD region gene 2 family, member C 3.15073
STX11 syntaxin 11 3.15073
FIMP1 fertilization-influencing membrane protein 1 3.15073
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10 3.15073
WNT16 wingless-type MMTV integration site family, member 16 3.15073
FAM228A family with sequence similarity 228, member A 3.15073
GATA2 GATA binding protein 2 3.15073
OR2T8 olfactory receptor, family 2, subfamily T, member 8 3.15073
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 3.15073
FAM237A family with sequence similarity 237 member A 3.15073
ANKRD42-DT ANKRD42 divergent transcript 3.15073
C8ORF90 chromosome 8 open reading frame 90 3.15073
H3C14 H3 clustered histone 14 3.15073
SERTM2 serine rich and transmembrane domain containing 2 3.15073
MSANTD5 Myb/SANT DNA binding domain containing 5 3.15073
TBXT T-box transcription factor T 3.15073
PTH1R parathyroid hormone 1 receptor 3.15073
OSTN osteocrin 3.15073
OR13H1 olfactory receptor, family 13, subfamily H, member 1 3.15073
ASIC4 acid sensing (proton gated) ion channel family member 4 3.15073
TBX22 T-box 22 3.15073
RAET1E retinoic acid early transcript 1E 3.15073
SIX1 SIX homeobox 1 3.15073
HLX H2.0-like homeobox 3.15073
AGTR1 angiotensin II receptor, type 1 3.15073
VCX2 variable charge, X-linked 2 3.15073
MYO7B myosin VIIB 3.15073
TXLNB taxilin beta 3.15073
MAGEB1 melanoma antigen family B1 3.15073
PRKCD protein kinase C, delta 3.15073
COX8C cytochrome c oxidase subunit VIIIC 3.15073
LRRC71 leucine rich repeat containing 71 3.15073
GSC goosecoid homeobox 3.15073
CDKN2A cyclin-dependent kinase inhibitor 2A 3.15073
C1QTNF8 C1q and tumor necrosis factor related protein 8 3.15073
MIP major intrinsic protein of lens fiber 3.15073
TLR8 toll-like receptor 8 3.15073
TIPE3 TNF alpha induced protein 8 like 3 3.15073
CHADL chondroadherin-like 3.15073
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 3.15073
MORC1 MORC family CW-type zinc finger 1 3.15073
PTCRA pre T-cell antigen receptor alpha 3.15073
CPA4 carboxypeptidase A4 3.15073
PCDHGA2 protocadherin gamma subfamily A, 2 3.15073
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2 3.15073
TAT tyrosine aminotransferase 3.15073
DNTT DNA nucleotidylexotransferase 3.15073
TEKT2 tektin 2 (testicular) 3.15073
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 3.15073
DHH desert hedgehog 3.15073
TEX36 testis expressed 36 3.15073
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6 3.15073
TRPM5 transient receptor potential cation channel, subfamily M, member 5 3.15073
CALHM3 calcium homeostasis modulator 3 3.15073
GAL3ST2 galactose-3-O-sulfotransferase 2 3.15073
FNDC9 fibronectin type III domain containing 9 3.15073
CCL24 chemokine (C-C motif) ligand 24 3.15073
FCN1 ficolin (collagen/fibrinogen domain containing) 1 3.15073
SUPT20HL1 suppressor of Ty 20 homolog (S. cerevisiae)-like 1 3.15073
SLC7A4 solute carrier family 7, member 4 3.15073
EFCAB3 EF-hand calcium binding domain 3 3.15073
CTAGE9 CTAGE family, member 9 3.15073
GCM1 glial cells missing homolog 1 (Drosophila) 3.15073
ZNF366 zinc finger protein 366 3.15073
SLCO1C1 solute carrier organic anion transporter family, member 1C1 3.15073
LHB luteinizing hormone beta polypeptide 3.15073
CTSE cathepsin E 3.15073
UBXN10 UBX domain protein 10 3.15073
OR13G1 olfactory receptor, family 13, subfamily G, member 1 3.15073
TSPAN19 tetraspanin 19 3.15073
GPR150 G protein-coupled receptor 150 3.15073
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 3.15073
MGP matrix Gla protein 3.15073
ZNF831 zinc finger protein 831 3.15073
GOLGA8Q golgin A8 family, member Q 3.15073
KIAA1755 KIAA1755 3.15073
ASCL2 achaete-scute family bHLH transcription factor 2 3.15073
NPC1L1 NPC1-like 1 3.15073
OCM oncomodulin 3.15073
TBX1 T-box 1 3.15073
CHRDL2 chordin-like 2 3.15073
PADI1 peptidyl arginine deiminase, type I 3.15073
FGB fibrinogen beta chain 3.15073
OR14A2 olfactory receptor, family 14, subfamily A, member 2 3.15073
ADRA1B adrenoceptor alpha 1B 3.15073
FATE1 fetal and adult testis expressed 1 3.15073
PLA2G12B phospholipase A2, group XIIB 3.15073
NTN1 netrin 1 3.15073
SAMD7 sterile alpha motif domain containing 7 3.15073
INCA1 inhibitor of CDK, cyclin A1 interacting protein 1 3.08695
LAMP5 lysosomal-associated membrane protein family, member 5 3.05288
MTERF1 mitochondrial transcription termination factor 1 2.93412
GRID2 glutamate receptor, ionotropic, delta 2 2.84879
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4 2.83233
KIAA0408 KIAA0408 2.76188
COPS5 COP9 signalosome subunit 5 2.72628
NEK1 NIMA-related kinase 1 2.72327
ZNHIT6 zinc finger, HIT-type containing 6 2.71839
C19ORF38 chromosome 19 open reading frame 38 2.71839
DBF4 DBF4 zinc finger 2.58252
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 2.55844
CDK16 cyclin-dependent kinase 16 2.52752
POLG polymerase (DNA directed), gamma 2.49792
SEPTIN11 septin 11 2.44757
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 2.40553
DROSHA drosha, ribonuclease type III 2.39876
PLEKHA3 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3 2.39525
KLHDC1 kelch domain containing 1 2.39525
PRH2 proline-rich protein HaeIII subfamily 2 2.39525
MIDN midnolin 2.38908
CCNG2 cyclin G2 2.38005
NDUFAF2 NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 2.38005
MAST1 microtubule associated serine/threonine kinase 1 2.37975
MCPH1 microcephalin 1 2.35507
RAB21 RAB21, member RAS oncogene family 2.34843
TST thiosulfate sulfurtransferase (rhodanese) 2.34843
DSC2 desmocollin 2 2.3175
SMYD3 SET and MYND domain containing 3 2.31582
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 2.31015
ZCWPW2 zinc finger, CW type with PWWP domain 2 2.30161
SLC66A1 solute carrier family 66 member 1 2.3011
TRNAU1AP tRNA selenocysteine 1 associated protein 1 2.27999
FBXL12 F-box and leucine-rich repeat protein 12 2.27687
GJC1 gap junction protein, gamma 1, 45kDa 2.27546
IP6K3 inositol hexakisphosphate kinase 3 2.27199
ATP10B ATPase, class V, type 10B 2.27199
GAGE10 G antigen 10 2.27199
TTL tubulin tyrosine ligase 2.27199
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled 2.27199
TMEM272 transmembrane protein 272 2.27199
H3C4 H3 clustered histone 4 2.27199
TBX10 T-box 10 2.27199
CCNE1 cyclin E1 2.27199
CA1 carbonic anhydrase I 2.27199
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) 2.27199
BEX5 brain expressed, X-linked 5 2.24595
HSPG2 heparan sulfate proteoglycan 2 2.23871
RAB5B RAB5B, member RAS oncogene family 2.19892
FXYD1 FXYD domain containing ion transport regulator 1 2.18468
ACTMAP actin maturation protease 2.17746
PARN poly(A)-specific ribonuclease 2.17307
ISOC1 isochorismatase domain containing 1 2.17307
LARP1 La ribonucleoprotein domain family, member 1 2.16209
POC1B-DUSP6 POC1B-DUSP6 readthrough 2.14591
TIMCC TIM double twin CX3C motif chaperone 2.13978
LRRC20 leucine rich repeat containing 20 2.12689
GPRC5B G protein-coupled receptor, class C, group 5, member B 2.11942
BEND7 BEN domain containing 7 2.10316
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 2.10143
HELZ2 helicase with zinc finger 2, transcriptional coactivator 2.08881
SYAP1 synapse associated protein 1 2.07958
MTCL1 microtubule crosslinking factor 1 2.07945
TTC7B tetratricopeptide repeat domain 7B 2.0713
DAZAP2 DAZ associated protein 2 2.06916
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 2.06472
ADGRL2 adhesion G protein-coupled receptor L2 2.05822
LHX8 LIM homeobox 8 2.05822
ZIK1 zinc finger protein interacting with K protein 1 2.03408
DPP8 dipeptidyl-peptidase 8 2.02944
PLAGL1 pleiomorphic adenoma gene-like 1 2.01812
OR2H2 olfactory receptor, family 2, subfamily H, member 2 2.01526
GPAA1 glycosylphosphatidylinositol anchor attachment 1 2.00638
USP9X ubiquitin specific peptidase 9, X-linked 2.00638

decreased expression

Symbol Name Standardized Value
CYB561D1 cytochrome b561 family, member D1 -3.196
RTKN2 rhotekin 2 -3.196
SAXO4 stabilizer of axonemal microtubules 4 -3.15073
CYGB cytoglobin -3.15073
GET1 guided entry of tail-anchored proteins factor 1 -3.15073
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1 -3.15073
MLXIP MLX interacting protein -3.15073
RRAS2 related RAS viral (r-ras) oncogene homolog 2 -3.15073
ZNF146 zinc finger protein 146 -3.14541
ETFBKMT electron transfer flavoprotein subunit beta lysine methyltransferase -3.10101
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -3.0538
RSAD2 radical S-adenosyl methionine domain containing 2 -3.05224
TCEA3 transcription elongation factor A (SII), 3 -3.05224
EPHB3 EPH receptor B3 -3.05224
CDC20B cell division cycle 20B -3.05224
SIAH3 siah E3 ubiquitin protein ligase family member 3 -3.05224
GPR50 G protein-coupled receptor 50 -3.05224
CDCP2 CUB domain containing protein 2 -3.05224
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43 -3.05224
TNMD tenomodulin -3.05224
IRF4 interferon regulatory factor 4 -3.05224
C1QTNF1 C1q and tumor necrosis factor related protein 1 -3.05224
ZC2HC1B zinc finger, C2HC-type containing 1B -3.05224
ALG10B ALG10B, alpha-1,2-glucosyltransferase -3.05224
NUTM2D NUT family member 2D -3.05224
ANXA13 annexin A13 -3.05224
CDHR4 cadherin-related family member 4 -3.05224
CAMK2B calcium/calmodulin-dependent protein kinase II beta -3.05224
FAM151A family with sequence similarity 151, member A -3.05224
OSR1 odd-skipped related transciption factor 1 -3.05224
TMEM100 transmembrane protein 100 -3.05224
TMEM176B transmembrane protein 176B -3.05224
CD300A CD300a molecule -3.05224
LOC122526780 uncharacterized LOC122526780 -3.05224
NTN5 netrin 5 -3.05224
ADGB androglobin -3.05224
TMEM139 transmembrane protein 139 -3.05224
HPX hemopexin -3.05224
RAPSN receptor-associated protein of the synapse -3.05224
KLRK1 killer cell lectin-like receptor subfamily K, member 1 -3.05224
SACK1A scaffolding CK1 anchoring protein A -3.05224
TDRD10 tudor domain containing 10 -3.05224
ACOT12 acyl-CoA thioesterase 12 -3.05224
LIN37 lin-37 DREAM MuvB core complex component -3.00312
GCNT7 glucosaminyl (N-acetyl) transferase family member 7 -2.92554
ANKRD26 ankyrin repeat domain 26 -2.92554
FOXRED1 FAD-dependent oxidoreductase domain containing 1 -2.83483
CNIH1 cornichon family AMPA receptor auxiliary protein 1 -2.82798
ADGRG3 adhesion G protein-coupled receptor G3 -2.74943
MRO maestro -2.72327
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2 -2.65439
AQP5 aquaporin 5 -2.57627
ELOB elongin B -2.57478
RPL36 ribosomal protein L36 -2.53873
TMEM14C transmembrane protein 14C -2.49792
MAK male germ cell-associated kinase -2.48096
SLC35A4 solute carrier family 35, member A4 -2.44757
STIM2 stromal interaction molecule 2 -2.40878
TMEM238 transmembrane protein 238 -2.4076
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12 -2.40647
TYMS thymidylate synthetase -2.39797
ANGPT4 angiopoietin 4 -2.39525
C2ORF72 chromosome 2 open reading frame 72 -2.39525
MICALL1 MICAL-like 1 -2.38069
FAM90A1 family with sequence similarity 90, member A1 -2.38005
DKK2 dickkopf WNT signaling pathway inhibitor 2 -2.38005
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 -2.38005
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3 -2.36909
EML1 echinoderm microtubule associated protein like 1 -2.36386
PDGFB platelet-derived growth factor beta polypeptide -2.36386
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 -2.36386
H3-3B H3.3 histone B -2.35507
RHOBTB3 Rho-related BTB domain containing 3 -2.35384
DCXR dicarbonyl/L-xylulose reductase -2.35342
MACROH2A2 macroH2A.2 histone -2.34843
UBE2W ubiquitin-conjugating enzyme E2W (putative) -2.34458
RPS3A ribosomal protein S3A -2.28323
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 -2.27999
SNAP47 synaptosomal-associated protein, 47kDa -2.27999
ACTN4 actinin, alpha 4 -2.27199
PPP1R16A protein phosphatase 1, regulatory subunit 16A -2.27179
ATG101 autophagy related 101 -2.27114
LRIG3 leucine-rich repeats and immunoglobulin-like domains 3 -2.27114
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta -2.25724
ARL1 ADP-ribosylation factor-like 1 -2.24703
ALS2 amyotrophic lateral sclerosis 2 (juvenile) -2.24414
ABHD17A abhydrolase domain containing 17A -2.24115
STOML2 stomatin (EPB72)-like 2 -2.24115
TBP TATA box binding protein -2.22561
ANAPC16 anaphase promoting complex subunit 16 -2.19892
KIF13B kinesin family member 13B -2.19892
POLI polymerase (DNA directed) iota -2.19811
HMBS hydroxymethylbilane synthase -2.19219
PHYHIPL phytanoyl-CoA 2-hydroxylase interacting protein-like -2.17168
RAB30 RAB30, member RAS oncogene family -2.16974
PPP1R3E protein phosphatase 1, regulatory subunit 3E -2.16209
ENHO energy homeostasis associated -2.16187
ZNF224 zinc finger protein 224 -2.14316
SV2A synaptic vesicle glycoprotein 2A -2.10994
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like -2.1098
FNDC3A fibronectin type III domain containing 3A -2.10316
NRBP2 nuclear receptor binding protein 2 -2.10143
RGS20 regulator of G-protein signaling 20 -2.10143
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 -2.09894
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 -2.08881
ZNF768 zinc finger protein 768 -2.07958
MTBP MDM2 binding protein -2.07221
COPS3 COP9 signalosome subunit 3 -2.06472
DNASE2 deoxyribonuclease II, lysosomal -2.05118
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -2.0507
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa -2.04776
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 -2.04776
BCAP29 B-cell receptor-associated protein 29 -2.03918
P3H2 prolyl 3-hydroxylase 2 -2.03408
KLHDC8A kelch domain containing 8A -2.02726
TRAPPC1 trafficking protein particle complex 1 -2.01806
OR56A1 olfactory receptor, family 56, subfamily A, member 1 -2.01666
REEP5 receptor accessory protein 5 -2.01572
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 -2.0082
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) -2.00743
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 -2.00104