| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | runt-related transcription factor 1|Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 861) |
| External Link | https://ncbi.nlm.nih.gov/gene/861 |
| Similar Terms | |
| Downloads & Tools |
497 genes differentially expressed following the RUNX1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.0152234 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.0111386 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00986476 |
| ADM | adrenomedullin | 0.00984747 |
| MT1E | metallothionein 1E | 0.00946865 |
| IFI44L | interferon-induced protein 44-like | 0.00946647 |
| SNAI2 | snail family zinc finger 2 | 0.00917356 |
| KLF9 | Kruppel-like factor 9 | 0.00892524 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.00884293 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.00873152 |
| CD38 | CD38 molecule | 0.00872067 |
| WBP5 | WW domain binding protein 5 | 0.00863913 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.00834808 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.00819317 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00816775 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00814922 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.00797601 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.00783002 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00777402 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00764376 |
| NID2 | nidogen 2 (osteonidogen) | 0.00763176 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00757326 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00754585 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00751669 |
| LEPROT | leptin receptor overlapping transcript | 0.00734848 |
| OPN3 | opsin 3 | 0.00732931 |
| TNC | tenascin C | 0.0073279 |
| NCAM1 | neural cell adhesion molecule 1 | 0.00725628 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00724517 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00724419 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00722077 |
| IL7R | interleukin 7 receptor | 0.00712855 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00711207 |
| DUSP5 | dual specificity phosphatase 5 | 0.00708623 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | 0.00703355 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | 0.00687378 |
| FKBP11 | FK506 binding protein 11, 19 kDa | 0.00686416 |
| GOLGA8A | golgin A8 family, member A | 0.00685275 |
| TUBA4A | tubulin, alpha 4a | 0.00677046 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.00664846 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | 0.00661988 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00658113 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00655652 |
| PLS3 | plastin 3 | 0.00652284 |
| APOD | apolipoprotein D | 0.00644962 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00641201 |
| EREG | epiregulin | 0.00638862 |
| XAF1 | XIAP associated factor 1 | 0.00634145 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00632509 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.00631235 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 0.00630097 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.00616789 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.00616305 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00612271 |
| MT1H | metallothionein 1H | 0.00608901 |
| KLF2 | Kruppel-like factor 2 | 0.00606705 |
| MCOLN1 | mucolipin 1 | 0.00603738 |
| AEBP1 | AE binding protein 1 | 0.00603489 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00602773 |
| MMP9 | matrix metallopeptidase 9 | 0.00600877 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.00600102 |
| CHP1 | calcineurin-like EF-hand protein 1 | 0.00599554 |
| PDGFD | platelet derived growth factor D | 0.00597829 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.00592302 |
| MT2A | metallothionein 2A | 0.00591661 |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 | 0.00590955 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.0058875 |
| RUFY3 | RUN and FYVE domain containing 3 | 0.00587843 |
| GAL | galanin/GMAP prepropeptide | 0.0058399 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00572971 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | 0.00570139 |
| GOLT1B | golgi transport 1B | 0.00568722 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0056545 |
| TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 | 0.0056512 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.00562743 |
| XYLT1 | xylosyltransferase I | 0.00561714 |
| CRABP1 | cellular retinoic acid binding protein 1 | 0.00561092 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.0056061 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00560576 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.00560108 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | 0.00559697 |
| PLXNC1 | plexin C1 | 0.00559661 |
| MINK1 | misshapen-like kinase 1 | 0.00558182 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.00551286 |
| XIC | X chromosome inactivation center | 0.00550959 |
| KLF10 | Kruppel-like factor 10 | 0.0055007 |
| DIPK1A | divergent protein kinase domain 1A | 0.00547203 |
| MT1X | metallothionein 1X | 0.00546868 |
| IER5 | immediate early response 5 | 0.00546362 |
| DUSP2 | dual specificity phosphatase 2 | 0.00546348 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00546135 |
| DEPTOR | DEP domain containing MTOR-interacting protein | 0.00545978 |
| GPR137B | G protein-coupled receptor 137B | 0.00545629 |
| COL11A1 | collagen, type XI, alpha 1 | 0.00542997 |
| S100A9 | S100 calcium binding protein A9 | 0.00541212 |
| PXDC1 | PX domain containing 1 | 0.00540681 |
| CRBN | cereblon | 0.00540558 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.00540111 |
| MRPS2 | mitochondrial ribosomal protein S2 | 0.00539385 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0053806 |
| IFRD1 | interferon-related developmental regulator 1 | 0.00536406 |
| MFAP5 | microfibrillar associated protein 5 | 0.00536228 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00535251 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | 0.00535207 |
| BMERB1 | bMERB domain containing 1 | 0.00531708 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.00531162 |
| CAPN1 | calpain 1, (mu/I) large subunit | 0.00531114 |
| MAP7 | microtubule-associated protein 7 | 0.00530484 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.00529124 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.00528752 |
| SPEN | spen family transcriptional repressor | 0.00528393 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.0052736 |
| THBS1 | thrombospondin 1 | 0.00526796 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.00524981 |
| NXN | nucleoredoxin | 0.00524233 |
| ROPN1B | rhophilin associated tail protein 1B | 0.00519279 |
| S100A7 | S100 calcium binding protein A7 | 0.00519018 |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa | 0.00518376 |
| PIGR | polymeric immunoglobulin receptor | 0.00517709 |
| SDC3 | syndecan 3 | 0.00517617 |
| ZC3H12A | zinc finger CCCH-type containing 12A | 0.00517575 |
| ZNF277 | zinc finger protein 277 | 0.00517463 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00517391 |
| SIRT3 | sirtuin 3 | 0.00516406 |
| REXO2 | RNA exonuclease 2 | 0.00514708 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 0.00513895 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0051335 |
| CBS | cystathionine-beta-synthase | 0.00512132 |
| KIAA0125 | KIAA0125 | 0.0051196 |
| CEL | carboxyl ester lipase | 0.0051182 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.00511739 |
| NPTX2 | neuronal pentraxin II | 0.00510538 |
| CLIP3 | CAP-GLY domain containing linker protein 3 | 0.00507319 |
| MT1G | metallothionein 1G | 0.00506451 |
| PLK2 | polo-like kinase 2 | 0.00503792 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.00503227 |
| PLAU | plasminogen activator, urokinase | 0.00500051 |
| CD79A | CD79a molecule, immunoglobulin-associated alpha | 0.0049996 |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 | 0.00498544 |
| MAMLD1 | mastermind-like domain containing 1 | 0.00498398 |
| USP3 | ubiquitin specific peptidase 3 | 0.00496823 |
| TXNDC9 | thioredoxin domain containing 9 | 0.00496792 |
| TSPO | translocator protein (18kDa) | 0.00495398 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | 0.00494409 |
| KLHL24 | kelch-like family member 24 | 0.00493945 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.00493854 |
| CD48 | CD48 molecule | 0.00493187 |
| RGS16 | regulator of G-protein signaling 16 | 0.00489427 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 | 0.00489407 |
| CROCCP2 | ciliary rootlet coiled-coil, rootletin pseudogene 2 | 0.00488941 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.00487804 |
| GATA1 | GATA binding protein 1 (globin transcription factor 1) | 0.00486955 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.00486775 |
| RAP2B | RAP2B, member of RAS oncogene family | 0.00486668 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.00486409 |
| TXNL1 | thioredoxin-like 1 | 0.00484731 |
| PFN2 | profilin 2 | 0.0048434 |
| SLAMF7 | SLAM family member 7 | 0.00483919 |
| RNF167 | ring finger protein 167 | 0.00483766 |
| PTTG1 | pituitary tumor-transforming 1 | 0.00483394 |
| KYNU | kynureninase | 0.00481522 |
| CHGA | chromogranin A | 0.00481133 |
| SFRP4 | secreted frizzled-related protein 4 | 0.0048068 |
| CUTA | cutA divalent cation tolerance homolog (E. coli) | 0.0048063 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00480245 |
| SFN | stratifin | 0.00479715 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.00479381 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.00479102 |
| DUSP10 | dual specificity phosphatase 10 | 0.00477065 |
| TMEM246 | transmembrane protein 246 | 0.0047703 |
| TRIB2 | tribbles pseudokinase 2 | 0.00476318 |
| COL2A1 | collagen, type II, alpha 1 | 0.00475803 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | 0.00475026 |
| CD320 | CD320 molecule | 0.00472265 |
| TMEM255A | transmembrane protein 255A | 0.00471925 |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing | 0.00471162 |
| FBXW12 | F-box and WD repeat domain containing 12 | 0.00469464 |
| PLXNA2 | plexin A2 | 0.00468275 |
| VGLL4 | vestigial-like family member 4 | 0.00468085 |
| EIF3M | eukaryotic translation initiation factor 3, subunit M | 0.00467986 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00467452 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | 0.00466458 |
| RTP4 | receptor (chemosensory) transporter protein 4 | 0.00465651 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.004655 |
| MXRA8 | matrix-remodelling associated 8 | 0.00465285 |
| CD44 | CD44 molecule (Indian blood group) | 0.00465016 |
| RGS20 | regulator of G-protein signaling 20 | 0.00464288 |
| PER1 | period circadian clock 1 | 0.00464286 |
| CAST | calpastatin | 0.00463937 |
| TXNIP | thioredoxin interacting protein | 0.00463779 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.00462864 |
| ASPH | aspartate beta-hydroxylase | 0.00459755 |
| LMNA | lamin A/C | 0.00459669 |
| MRPL40 | mitochondrial ribosomal protein L40 | 0.00459263 |
| CENPU | centromere protein U | 0.00459002 |
| SCAF4 | SR-related CTD-associated factor 4 | 0.00457605 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00457309 |
| DPP6 | dipeptidyl-peptidase 6 | 0.00457269 |
| INSL3 | insulin-like 3 (Leydig cell) | 0.00454967 |
| BEX4 | brain expressed, X-linked 4 | 0.00454639 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.00454325 |
| NUP210 | nucleoporin 210kDa | 0.00453267 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00452825 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | 0.00452084 |
| VPREB3 | pre-B lymphocyte 3 | 0.00451904 |
| COPS2 | COP9 signalosome subunit 2 | 0.00451264 |
| SERPINB7 | serpin peptidase inhibitor, clade B (ovalbumin), member 7 | 0.00451246 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.00451049 |
| KAT2B | K(lysine) acetyltransferase 2B | 0.00450162 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) | 0.00449988 |
| TSPYL5 | TSPY-like 5 | 0.00449088 |
| GUCA2A | guanylate cyclase activator 2A (guanylin) | 0.00448717 |
| ZNF160 | zinc finger protein 160 | 0.00447837 |
| C3 | complement component 3 | 0.00447685 |
| PMM1 | phosphomannomutase 1 | 0.00447372 |
| ZNHIT1 | zinc finger, HIT-type containing 1 | 0.00446435 |
| ZCCHC2 | zinc finger, CCHC domain containing 2 | 0.00445036 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | 0.00444399 |
| TMEM159 | transmembrane protein 159 | 0.00444332 |
| TSPAN4 | tetraspanin 4 | 0.00443901 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.00440534 |
| REG1A | regenerating islet-derived 1 alpha | 0.00438552 |
| TYR | tyrosinase | 0.00437497 |
| AHNAK | AHNAK nucleoprotein | 0.00437407 |
| PPIE | peptidylprolyl isomerase E (cyclophilin E) | 0.00436449 |
| RASAL1 | RAS protein activator like 1 (GAP1 like) | 0.00436379 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00436241 |
| ABCC10 | ATP-binding cassette, sub-family C (CFTR/MRP), member 10 | 0.00434876 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | 0.00433979 |
| FAM189A2 | family with sequence similarity 189, member A2 | 0.00433711 |
| RORA | RAR-related orphan receptor A | 0.00433644 |
| RTCA | RNA 3'-terminal phosphate cyclase | 0.00431561 |
| FBN2 | fibrillin 2 | 0.00430835 |
| HIST1H2BK | histone cluster 1, H2bk | 0.00430688 |
| SIX2 | SIX homeobox 2 | 0.00430395 |
| NPTN | neuroplastin | 0.00429976 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.00429675 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.00428541 |
| LONP2 | lon peptidase 2, peroxisomal | 0.00427566 |
| FNDC3A | fibronectin type III domain containing 3A | 0.00427129 |
| TM4SF4 | transmembrane 4 L six family member 4 | 0.00426283 |
| ING2 | inhibitor of growth family, member 2 | 0.00426201 |
| GPATCH8 | G patch domain containing 8 | 0.00424503 |
| DEFB4A | defensin, beta 4A | 0.00421566 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | 0.00421522 |
| THAP11 | THAP domain containing 11 | 0.00421328 |
| SLC46A3 | solute carrier family 46, member 3 | 0.00421152 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0042109 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0042035 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ANXA3 | annexin A3 | -0.0160439 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0147433 |
| TNNC1 | troponin C type 1 (slow) | -0.0116181 |
| ADI1 | acireductone dioxygenase 1 | -0.0115908 |
| S100P | S100 calcium binding protein P | -0.0115526 |
| LYZ | lysozyme | -0.0109726 |
| TFF1 | trefoil factor 1 | -0.0106048 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.0101211 |
| CD93 | CD93 molecule | -0.00993767 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | -0.00927634 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.00925034 |
| NEFH | neurofilament, heavy polypeptide | -0.00897825 |
| MYBPC1 | myosin binding protein C, slow type | -0.00872493 |
| SRGN | serglycin | -0.00871195 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00867971 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | -0.00862673 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.00856036 |
| ODAM | odontogenic, ameloblast asssociated | -0.00851303 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.00846557 |
| CKM | creatine kinase, muscle | -0.00838359 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.00834483 |
| CD9 | CD9 molecule | -0.00832001 |
| TSPAN8 | tetraspanin 8 | -0.00831103 |
| ANOS1 | anosmin 1 | -0.00827235 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.00816263 |
| MB | myoglobin | -0.0080757 |
| MSLN | mesothelin | -0.00803603 |
| FABP7 | fatty acid binding protein 7, brain | -0.00799707 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | -0.00798982 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.00790055 |
| FBP1 | fructose-1,6-bisphosphatase 1 | -0.00776996 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.00774063 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | -0.00768379 |
| TFDP1 | transcription factor Dp-1 | -0.00767161 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00764881 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.00762073 |
| MYO5C | myosin VC | -0.00758232 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.00755616 |
| HOXB7 | homeobox B7 | -0.00755335 |
| CSTA | cystatin A (stefin A) | -0.00751028 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.00749474 |
| PDZK1 | PDZ domain containing 1 | -0.00748015 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 | -0.00744713 |
| ZNF185 | zinc finger protein 185 (LIM domain) | -0.00744578 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 | -0.00744497 |
| OLFM4 | olfactomedin 4 | -0.00743088 |
| C8ORF4 | chromosome 8 open reading frame 4 | -0.00740737 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00736658 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | -0.00732104 |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 | -0.00725166 |
| CALML4 | calmodulin-like 4 | -0.00723036 |
| ADIRF | adipogenesis regulatory factor | -0.00719396 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.00716283 |
| FAR2 | fatty acyl CoA reductase 2 | -0.00714689 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.00714627 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.00707465 |
| SPP1 | secreted phosphoprotein 1 | -0.00706247 |
| CAV2 | caveolin 2 | -0.00705983 |
| DACH1 | dachshund family transcription factor 1 | -0.00704413 |
| NCF2 | neutrophil cytosolic factor 2 | -0.00700894 |
| MECOM | MDS1 and EVI1 complex locus | -0.00699773 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | -0.00698403 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00697508 |
| HOXB6 | homeobox B6 | -0.00696786 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.0069428 |
| PODXL | podocalyxin-like | -0.00694048 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.00691996 |
| EMX2 | empty spiracles homeobox 2 | -0.00688503 |
| FAM169A | family with sequence similarity 169, member A | -0.0068781 |
| SEPHS1 | selenophosphate synthetase 1 | -0.00687524 |
| NEBL | nebulette | -0.00681393 |
| ACP6 | acid phosphatase 6, lysophosphatidic | -0.00676705 |
| TTN | titin | -0.00668128 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | -0.00665222 |
| ZNF589 | zinc finger protein 589 | -0.00660573 |
| GAB2 | GRB2-associated binding protein 2 | -0.00660231 |
| RNASET2 | ribonuclease T2 | -0.00656537 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | -0.00656242 |
| CES1 | carboxylesterase 1 | -0.00655583 |
| AGR2 | anterior gradient 2 | -0.0064892 |
| GCA | grancalcin, EF-hand calcium binding protein | -0.00643079 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.0064055 |
| MXRA5 | matrix-remodelling associated 5 | -0.00637846 |
| FERMT1 | fermitin family member 1 | -0.00636517 |
| DMXL1 | Dmx-like 1 | -0.00636028 |
| CFD | complement factor D (adipsin) | -0.00635718 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.0063494 |
| CETN2 | centrin, EF-hand protein, 2 | -0.00633948 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.00632876 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | -0.00628937 |
| CLU | clusterin | -0.00626983 |
| MYOZ2 | myozenin 2 | -0.00626309 |
| AOC1 | amine oxidase, copper containing 1 | -0.00625651 |
| HYOU1 | hypoxia up-regulated 1 | -0.00624139 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.00622533 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.00622521 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00620338 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.00618867 |
| MME | membrane metallo-endopeptidase | -0.0061621 |
| KLHL41 | kelch-like family member 41 | -0.00614568 |
| FAM107A | family with sequence similarity 107, member A | -0.00613231 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.00612004 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | -0.00607613 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00603011 |
| MANSC1 | MANSC domain containing 1 | -0.00602603 |
| RLN1 | relaxin 1 | -0.00602233 |
| FBXO11 | F-box protein 11 | -0.0059384 |
| FCGBP | Fc fragment of IgG binding protein | -0.00593113 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | -0.00589614 |
| SUMO3 | small ubiquitin-like modifier 3 | -0.00589184 |
| TPM3 | tropomyosin 3 | -0.00588718 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | -0.0058867 |
| XPO7 | exportin 7 | -0.00586333 |
| SYNGR2 | synaptogyrin 2 | -0.00585347 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.00583253 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | -0.00581544 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.0057808 |
| HBB | hemoglobin, beta | -0.00577342 |
| MMP12 | matrix metallopeptidase 12 | -0.00575676 |
| PRKCA | protein kinase C, alpha | -0.0057526 |
| XK | X-linked Kx blood group | -0.00573684 |
| NCAPD3 | non-SMC condensin II complex, subunit D3 | -0.00572158 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.00571908 |
| CPOX | coproporphyrinogen oxidase | -0.00570556 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00570329 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -0.00570201 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | -0.00569916 |
| ACOT9 | acyl-CoA thioesterase 9 | -0.00568887 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00565955 |
| NID1 | nidogen 1 | -0.00565773 |
| CARD10 | caspase recruitment domain family, member 10 | -0.00564748 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.00564512 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.00563274 |
| LY75 | lymphocyte antigen 75 | -0.0056069 |
| PHYH | phytanoyl-CoA 2-hydroxylase | -0.00558422 |
| KIAA0100 | KIAA0100 | -0.00557644 |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha | -0.00557421 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.00555367 |
| MYH3 | myosin, heavy chain 3, skeletal muscle, embryonic | -0.00553488 |
| TNNI1 | troponin I type 1 (skeletal, slow) | -0.00553104 |
| KIAA0232 | KIAA0232 | -0.00552087 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | -0.00551959 |
| SPC25 | SPC25, NDC80 kinetochore complex component | -0.00551568 |
| MAGED2 | melanoma antigen family D2 | -0.00551446 |
| CLIC5 | chloride intracellular channel 5 | -0.00550837 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00548465 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | -0.00547697 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | -0.00547566 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | -0.00545894 |
| ACKR3 | atypical chemokine receptor 3 | -0.00541968 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B | -0.00541688 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.00541533 |
| PLTP | phospholipid transfer protein | -0.00541381 |
| RAD51AP1 | RAD51 associated protein 1 | -0.00540515 |
| JADE3 | jade family PHD finger 3 | -0.00540446 |
| MSRB1 | methionine sulfoxide reductase B1 | -0.00540102 |
| BTG2 | BTG family, member 2 | -0.00536984 |
| ODC1 | ornithine decarboxylase 1 | -0.0053669 |
| OSBPL11 | oxysterol binding protein-like 11 | -0.00536651 |
| SLN | sarcolipin | -0.00536137 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00535184 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.00533463 |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | -0.00531536 |
| HEBP2 | heme binding protein 2 | -0.00530665 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.0052904 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 | -0.00528483 |
| IL1R2 | interleukin 1 receptor, type II | -0.00525165 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.00523937 |
| HMGN1 | high mobility group nucleosome binding domain 1 | -0.0052352 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -0.00522002 |
| ACTC1 | actin, alpha, cardiac muscle 1 | -0.00521664 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | -0.00520821 |
| KIF2C | kinesin family member 2C | -0.00519077 |
| MAGEA3 | melanoma antigen family A3 | -0.00516718 |
| MMP2 | matrix metallopeptidase 2 | -0.00516296 |
| CA3 | carbonic anhydrase III | -0.00515937 |
| CCN2 | cellular communication network factor 2 | -0.00515235 |
| SELE | selectin E | -0.00515223 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.00514915 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | -0.00514356 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | -0.00513914 |
| AOC3 | amine oxidase, copper containing 3 | -0.00513707 |
| ADD3 | adducin 3 (gamma) | -0.00511926 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | -0.0051158 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 | -0.00509201 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | -0.0050898 |
| POGK | pogo transposable element with KRAB domain | -0.00508322 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.0050638 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.00506059 |
| FZD5 | frizzled class receptor 5 | -0.00505556 |
| BCL3 | B-cell CLL/lymphoma 3 | -0.00504528 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | -0.0050415 |
| ANXA6 | annexin A6 | -0.00503618 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00502489 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.00502388 |
| TNNC2 | troponin C type 2 (fast) | -0.00500857 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | -0.00500243 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | -0.00499242 |
| ZNF423 | zinc finger protein 423 | -0.00498962 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.00497384 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.00496274 |
| RNASEH2A | ribonuclease H2, subunit A | -0.00495819 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00495295 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | -0.00494853 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 | -0.00492876 |
| TYROBP | TYRO protein tyrosine kinase binding protein | -0.00491522 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.00490871 |
| METRN | meteorin, glial cell differentiation regulator | -0.0048874 |
| TEAD4 | TEA domain family member 4 | -0.00488225 |
| CTPS2 | CTP synthase 2 | -0.0048656 |
| STAB1 | stabilin 1 | -0.00485883 |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | -0.00485872 |
| FABP1 | fatty acid binding protein 1, liver | -0.00485469 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00484519 |
| MCCC2 | methylcrotonoyl-CoA carboxylase 2 (beta) | -0.00484273 |
| CHMP2B | charged multivesicular body protein 2B | -0.00482882 |
| PLLP | plasmolipin | -0.00481829 |
| MAGEA4 | melanoma antigen family A4 | -0.00481826 |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | -0.00481181 |
| MCM10 | minichromosome maintenance complex component 10 | -0.0047976 |
| ARAP3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 | -0.0047957 |
| RIOX2 | ribosomal oxygenase 2 | -0.00477451 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 | -0.00475244 |
| DZIP1 | DAZ interacting zinc finger protein 1 | -0.0047475 |
| COL6A2 | collagen, type VI, alpha 2 | -0.00474582 |
| SORD | sorbitol dehydrogenase | -0.00473929 |
| PGK1 | phosphoglycerate kinase 1 | -0.00472758 |
| ASF1B | anti-silencing function 1B histone chaperone | -0.00471592 |
| GSS | glutathione synthetase | -0.00470058 |
| CSF3R | colony stimulating factor 3 receptor (granulocyte) | -0.00467742 |
| CD302 | CD302 molecule | -0.00466019 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -0.00465151 |
| ANPEP | alanyl (membrane) aminopeptidase | -0.00464773 |
| OBI1 | ORC ubiquitin ligase 1 | -0.00462998 |
| CDCA3 | cell division cycle associated 3 | -0.004623 |
| SMAD6 | SMAD family member 6 | -0.0046205 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | -0.00462008 |
| EGFL6 | EGF-like-domain, multiple 6 | -0.00460793 |
| EDN3 | endothelin 3 | -0.00459679 |
| KRT13 | keratin 13, type I | -0.00459676 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | -0.00459298 |
| MYOF | myoferlin | -0.00459262 |
| NLGN4X | neuroligin 4, X-linked | -0.00458663 |
| VWF | von Willebrand factor | -0.00456134 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 | -0.00455651 |
| HSPA8 | heat shock 70kDa protein 8 | -0.004548 |
| GUCY2C | guanylate cyclase 2C | -0.00454472 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | -0.0045422 |
