| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | runt-related transcription factor 2|This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 860) |
| External Link | https://ncbi.nlm.nih.gov/gene/860 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the RUNX2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TFF1 | trefoil factor 1 | 0.0174659 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.0140777 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0134384 |
| MBD1 | methyl-CpG binding domain protein 1 | 0.0133751 |
| CA2 | carbonic anhydrase II | 0.0133239 |
| GLOD4 | glyoxalase domain containing 4 | 0.0130039 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.0125346 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0124346 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.012116 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.0119249 |
| COL15A1 | collagen, type XV, alpha 1 | 0.011817 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.0115001 |
| TSPAN8 | tetraspanin 8 | 0.0112215 |
| ANPEP | alanyl (membrane) aminopeptidase | 0.0110841 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | 0.0110005 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | 0.0109988 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.010982 |
| KLF4 | Kruppel-like factor 4 (gut) | 0.0108329 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0107355 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | 0.0106435 |
| HHEX | hematopoietically expressed homeobox | 0.0105996 |
| MGLL | monoglyceride lipase | 0.0105665 |
| GAS1 | growth arrest-specific 1 | 0.0102975 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0102902 |
| SRPX | sushi-repeat containing protein, X-linked | 0.0102429 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.0101424 |
| SPON1 | spondin 1, extracellular matrix protein | 0.0101253 |
| MYO1C | myosin IC | 0.0100476 |
| IFI44 | interferon-induced protein 44 | 0.00988297 |
| MT1E | metallothionein 1E | 0.0098589 |
| JPT1 | Jupiter microtubule associated homolog 1 | 0.00984967 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.00960078 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.00920305 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | 0.00916948 |
| PDZK1 | PDZ domain containing 1 | 0.00915 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00914839 |
| ATF3 | activating transcription factor 3 | 0.00905629 |
| SST | somatostatin | 0.00902951 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00900575 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.00898827 |
| MT1F | metallothionein 1F | 0.00898696 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.0089492 |
| HOXB7 | homeobox B7 | 0.00871317 |
| RHOF | ras homolog family member F (in filopodia) | 0.00865276 |
| MT1G | metallothionein 1G | 0.00865199 |
| PLSCR4 | phospholipid scramblase 4 | 0.00864208 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00863535 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.00846555 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00843758 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 0.00840576 |
| EDNRB | endothelin receptor type B | 0.00829153 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00829044 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.00827595 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.00825907 |
| POLG2 | polymerase (DNA directed), gamma 2, accessory subunit | 0.00824595 |
| MEN1 | multiple endocrine neoplasia I | 0.00821212 |
| AOX1 | aldehyde oxidase 1 | 0.00815603 |
| PLP1 | proteolipid protein 1 | 0.00814811 |
| ARL14 | ADP-ribosylation factor-like 14 | 0.00811663 |
| FBN1 | fibrillin 1 | 0.00807686 |
| CYBRD1 | cytochrome b reductase 1 | 0.00806339 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.0079881 |
| KLK5 | kallikrein-related peptidase 5 | 0.00797984 |
| AGTR1 | angiotensin II receptor, type 1 | 0.00797316 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.00795318 |
| MT1M | metallothionein 1M | 0.00794088 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.00792951 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.00788932 |
| MT1H | metallothionein 1H | 0.00781797 |
| CCL8 | chemokine (C-C motif) ligand 8 | 0.00775224 |
| MFAP5 | microfibrillar associated protein 5 | 0.0077437 |
| XIC | X chromosome inactivation center | 0.00770772 |
| MX2 | MX dynamin-like GTPase 2 | 0.00769306 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.00768667 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.00764159 |
| MRPS16 | mitochondrial ribosomal protein S16 | 0.00755764 |
| EGR3 | early growth response 3 | 0.00750632 |
| TFRC | transferrin receptor | 0.00748835 |
| NPY1R | neuropeptide Y receptor Y1 | 0.0074735 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.00739439 |
| GALC | galactosylceramidase | 0.00738122 |
| ANK2 | ankyrin 2, neuronal | 0.0073464 |
| FHL1 | four and a half LIM domains 1 | 0.00734283 |
| OLFML2A | olfactomedin-like 2A | 0.00732025 |
| KLK8 | kallikrein-related peptidase 8 | 0.00730389 |
| HSPA2 | heat shock 70kDa protein 2 | 0.00729895 |
| ATG3 | autophagy related 3 | 0.00727343 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.00722188 |
| GATA6 | GATA binding protein 6 | 0.0071838 |
| BAALC | brain and acute leukemia, cytoplasmic | 0.00716327 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.00715792 |
| KLK6 | kallikrein-related peptidase 6 | 0.00713906 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00713754 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.00712445 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.00712221 |
| DUSP5 | dual specificity phosphatase 5 | 0.00709026 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated | 0.00705966 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.00704737 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00702854 |
| HOXB6 | homeobox B6 | 0.00695074 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.00695053 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | 0.00692068 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.00691752 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.00688965 |
| TFDP1 | transcription factor Dp-1 | 0.00688417 |
| OLFML3 | olfactomedin-like 3 | 0.00685123 |
| IL15 | interleukin 15 | 0.00684527 |
| CKS1B | CDC28 protein kinase regulatory subunit 1B | 0.00683123 |
| HSPA8 | heat shock 70kDa protein 8 | 0.00680651 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | 0.00679157 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.0067836 |
| ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide | 0.00677262 |
| KLF6 | Kruppel-like factor 6 | 0.00676584 |
| PDGFD | platelet derived growth factor D | 0.00676468 |
| RTN2 | reticulon 2 | 0.00676023 |
| PBK | PDZ binding kinase | 0.00674899 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.0067089 |
| PEX3 | peroxisomal biogenesis factor 3 | 0.00669248 |
| NRCAM | neuronal cell adhesion molecule | 0.00666121 |
| PNMA1 | paraneoplastic Ma antigen 1 | 0.00664204 |
| IFI44L | interferon-induced protein 44-like | 0.00664159 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.00663543 |
| RALB | v-ral simian leukemia viral oncogene homolog B | 0.00659357 |
| MX1 | MX dynamin-like GTPase 1 | 0.00658778 |
| GLUD2 | glutamate dehydrogenase 2 | 0.00656462 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa | 0.00656435 |
| CLIC5 | chloride intracellular channel 5 | 0.00655251 |
| LASP1 | LIM and SH3 protein 1 | 0.00654411 |
| PDGFRL | platelet-derived growth factor receptor-like | 0.00653916 |
| GOLM1 | golgi membrane protein 1 | 0.00653225 |
| GNG12 | guanine nucleotide binding protein (G protein), gamma 12 | 0.00652114 |
| SI | sucrase-isomaltase (alpha-glucosidase) | 0.00651246 |
| FNBP1 | formin binding protein 1 | 0.00649883 |
| OGN | osteoglycin | 0.00649414 |
| FABP1 | fatty acid binding protein 1, liver | 0.00649138 |
| IRS2 | insulin receptor substrate 2 | 0.00647864 |
| CTSC | cathepsin C | 0.00647195 |
| SNX10 | sorting nexin 10 | 0.00646178 |
| PFKP | phosphofructokinase, platelet | 0.00645005 |
| IFRD2 | interferon-related developmental regulator 2 | 0.00642332 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.006397 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.00635364 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.00635194 |
| CD200 | CD200 molecule | 0.00634295 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.00633726 |
| PLAT | plasminogen activator, tissue | 0.00631623 |
| C1ORF115 | chromosome 1 open reading frame 115 | 0.00631482 |
| ANXA1 | annexin A1 | 0.00630715 |
| MT2A | metallothionein 2A | 0.00629372 |
| NID1 | nidogen 1 | 0.00629127 |
| AGPS | alkylglycerone phosphate synthase | 0.00629036 |
| TXN | thioredoxin | 0.00628909 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.00628903 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | 0.00628778 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00627136 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.00626299 |
| SELENOT | selenoprotein T | 0.00625893 |
| ASS1 | argininosuccinate synthase 1 | 0.00625867 |
| HNRNPF | heterogeneous nuclear ribonucleoprotein F | 0.00623859 |
| GHITM | growth hormone inducible transmembrane protein | 0.00623339 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | 0.00621074 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | 0.00618825 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | 0.00618766 |
| SLC35A5 | solute carrier family 35, member A5 | 0.0061862 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | 0.00617936 |
| L1CAM | L1 cell adhesion molecule | 0.0061773 |
| EGR2 | early growth response 2 | 0.00614711 |
| PCBP1 | poly(rC) binding protein 1 | 0.00612664 |
| MSH2 | mutS homolog 2 | 0.0061121 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.00608799 |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | 0.00608491 |
| DCN | decorin | 0.00607799 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | 0.00606276 |
| EDN3 | endothelin 3 | 0.00605524 |
| KLK11 | kallikrein-related peptidase 11 | 0.00603467 |
| MAGEA3 | melanoma antigen family A3 | 0.00601745 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | 0.00599064 |
| MT1HL1 | metallothionein 1H-like 1 | 0.0059682 |
| PRDX3 | peroxiredoxin 3 | 0.0059515 |
| HSPE1 | heat shock 10kDa protein 1 | 0.00594849 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.00594686 |
| S100B | S100 calcium binding protein B | 0.00593163 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | 0.00593111 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | 0.00590311 |
| STK10 | serine/threonine kinase 10 | 0.00589929 |
| MAGEA12 | melanoma antigen family A12 | 0.00588885 |
| ETNK1 | ethanolamine kinase 1 | 0.00588647 |
| PTEN | phosphatase and tensin homolog | 0.00588612 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.00588162 |
| PDCD6 | programmed cell death 6 | 0.00588075 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.00587969 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.00587958 |
| ME2 | malic enzyme 2, NAD(+)-dependent, mitochondrial | 0.00585999 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.00585391 |
| RECK | reversion-inducing-cysteine-rich protein with kazal motifs | 0.00585135 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | 0.00584604 |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | 0.00584005 |
| JAM2 | junctional adhesion molecule 2 | 0.00581223 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.00581099 |
| TMEM230 | transmembrane protein 230 | 0.00580937 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | 0.00580335 |
| FZD6 | frizzled class receptor 6 | 0.00579859 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | 0.00579093 |
| C21ORF91 | chromosome 21 open reading frame 91 | 0.00578886 |
| HEPH | hephaestin | 0.00578672 |
| FCGBP | Fc fragment of IgG binding protein | 0.00578155 |
| NDC1 | NDC1 transmembrane nucleoporin | 0.00577281 |
| SGCE | sarcoglycan, epsilon | 0.0057714 |
| MYBPC1 | myosin binding protein C, slow type | 0.00576956 |
| ZG16 | zymogen granule protein 16 | 0.00576586 |
| SNX11 | sorting nexin 11 | 0.00573397 |
| CD69 | CD69 molecule | 0.00571773 |
| FMO1 | flavin containing monooxygenase 1 | 0.00569176 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.00568961 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.00568117 |
| ASRGL1 | asparaginase like 1 | 0.00567774 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | 0.00566283 |
| DCHS1 | dachsous cadherin-related 1 | 0.00566189 |
| ZNF706 | zinc finger protein 706 | 0.00565198 |
| GSTA1 | glutathione S-transferase alpha 1 | 0.00564437 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00562317 |
| TSPAN6 | tetraspanin 6 | 0.00562153 |
| AMDHD2 | amidohydrolase domain containing 2 | 0.00561302 |
| MDFIC | MyoD family inhibitor domain containing | 0.00560933 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0055849 |
| IRF1 | interferon regulatory factor 1 | 0.00556865 |
| WDR61 | WD repeat domain 61 | 0.00556177 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 | 0.00555572 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.00554603 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00553487 |
| KIF5C | kinesin family member 5C | 0.00551454 |
| ADAM12 | ADAM metallopeptidase domain 12 | 0.00551129 |
| CANX | calnexin | 0.00550311 |
| CCR7 | chemokine (C-C motif) receptor 7 | 0.00550074 |
| SOX17 | SRY (sex determining region Y)-box 17 | 0.0054986 |
| NLRP2 | NLR family, pyrin domain containing 2 | 0.00548861 |
| IL6 | interleukin 6 | 0.00548717 |
| CCN2 | cellular communication network factor 2 | 0.00548031 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 0.00547656 |
| PALLD | palladin, cytoskeletal associated protein | 0.00547388 |
| ITGA6 | integrin, alpha 6 | 0.00547197 |
| FA2H | fatty acid 2-hydroxylase | 0.00546265 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00545937 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | 0.00545656 |
| PPIF | peptidylprolyl isomerase F | 0.00545173 |
| LAMA2 | laminin, alpha 2 | 0.00542523 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.00541987 |
| TPBG | trophoblast glycoprotein | 0.00541439 |
| AADAC | arylacetamide deacetylase | 0.00539211 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0212269 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | -0.0183705 |
| MMP9 | matrix metallopeptidase 9 | -0.0162087 |
| PTK2 | protein tyrosine kinase 2 | -0.0136574 |
| AUTS2 | autism susceptibility candidate 2 | -0.0130941 |
| S100A2 | S100 calcium binding protein A2 | -0.0129803 |
| CD9 | CD9 molecule | -0.0126534 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0121534 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.0120997 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.0116825 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.0116222 |
| SIRT3 | sirtuin 3 | -0.0113722 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.0113637 |
| KRT5 | keratin 5, type II | -0.0111953 |
| ALOX5 | arachidonate 5-lipoxygenase | -0.0110242 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0106661 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.0104449 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.0103932 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | -0.0100351 |
| CSTA | cystatin A (stefin A) | -0.0099858 |
| STK39 | serine threonine kinase 39 | -0.00970577 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | -0.0094755 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00936909 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00911641 |
| S100A8 | S100 calcium binding protein A8 | -0.00909386 |
| MMP7 | matrix metallopeptidase 7 | -0.00907865 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0090221 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.00895493 |
| SFTPB | surfactant protein B | -0.00895146 |
| KRT14 | keratin 14, type I | -0.00893037 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | -0.00892515 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.00891836 |
| CD52 | CD52 molecule | -0.008894 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00881344 |
| SFTPA2 | surfactant protein A2 | -0.00868081 |
| SFTPD | surfactant protein D | -0.00856505 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.00854459 |
| KLHDC10 | kelch domain containing 10 | -0.008477 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00826636 |
| MYO6 | myosin VI | -0.00822196 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00817878 |
| LTF | lactotransferrin | -0.00817089 |
| RBM34 | RNA binding motif protein 34 | -0.00804955 |
| CYBB | cytochrome b-245, beta polypeptide | -0.00804467 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | -0.00792188 |
| PKP1 | plakophilin 1 | -0.0079104 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.007868 |
| LTA4H | leukotriene A4 hydrolase | -0.00786145 |
| STEAP3 | STEAP family member 3, metalloreductase | -0.00781305 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | -0.00780394 |
| MB | myoglobin | -0.00779513 |
| HP | haptoglobin | -0.00779433 |
| H1-0 | H1.0 linker histone | -0.00778611 |
| JAG1 | jagged 1 | -0.00777199 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | -0.00767182 |
| CA12 | carbonic anhydrase XII | -0.00752358 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.00748952 |
| IPO13 | importin 13 | -0.00745561 |
| FN1 | fibronectin 1 | -0.00740916 |
| BLNK | B-cell linker | -0.00735408 |
| IL7R | interleukin 7 receptor | -0.00735222 |
| CLEC7A | C-type lectin domain family 7, member A | -0.00733286 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.00729104 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | -0.00728846 |
| TXNIP | thioredoxin interacting protein | -0.0072775 |
| SFN | stratifin | -0.00722781 |
| ANO10 | anoctamin 10 | -0.00721866 |
| VEGFA | vascular endothelial growth factor A | -0.0072099 |
| CLEC5A | C-type lectin domain family 5, member A | -0.0072089 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.00718539 |
| NAV2 | neuron navigator 2 | -0.0071015 |
| AREG | amphiregulin | -0.00704648 |
| KRT17 | keratin 17, type I | -0.00704351 |
| TSPAN5 | tetraspanin 5 | -0.00704134 |
| COL2A1 | collagen, type II, alpha 1 | -0.00704 |
| CTSH | cathepsin H | -0.00702917 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | -0.00699285 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | -0.00697457 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.00693328 |
| BRD2 | bromodomain containing 2 | -0.00684281 |
| NOTCH3 | notch 3 | -0.00676012 |
| KRT15 | keratin 15, type I | -0.00675578 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | -0.00674758 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | -0.00673364 |
| BPGM | 2,3-bisphosphoglycerate mutase | -0.00666772 |
| SDC1 | syndecan 1 | -0.00666311 |
| USP47 | ubiquitin specific peptidase 47 | -0.0066466 |
| E2F2 | E2F transcription factor 2 | -0.00664618 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 | -0.00661603 |
| COCH | cochlin | -0.00660127 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.00656419 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.00653642 |
| HOXC10 | homeobox C10 | -0.00649558 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00647282 |
| EFNB2 | ephrin-B2 | -0.0064474 |
| GSDME | gasdermin E | -0.0064413 |
| PRKCZ | protein kinase C, zeta | -0.00643338 |
| SPRR3 | small proline-rich protein 3 | -0.0063471 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00632711 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.00631724 |
| DLX5 | distal-less homeobox 5 | -0.00631568 |
| KDM5A | lysine (K)-specific demethylase 5A | -0.00629396 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.00627535 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.00625729 |
| EIF3L | eukaryotic translation initiation factor 3, subunit L | -0.00625681 |
| FPR1 | formyl peptide receptor 1 | -0.0062528 |
| RWDD1 | RWD domain containing 1 | -0.00623814 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | -0.00623159 |
| ZNF331 | zinc finger protein 331 | -0.00621952 |
| KRT13 | keratin 13, type I | -0.00621327 |
| ARG2 | arginase 2 | -0.00620248 |
| LCN2 | lipocalin 2 | -0.0061994 |
| POU2AF1 | POU class 2 associating factor 1 | -0.00618904 |
| SPRR1B | small proline-rich protein 1B | -0.00613302 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -0.00612644 |
| AZU1 | azurocidin 1 | -0.00610634 |
| ITGAV | integrin, alpha V | -0.0060863 |
| ORM1 | orosomucoid 1 | -0.00608509 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.0060407 |
| SQLE | squalene epoxidase | -0.0060375 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | -0.00599577 |
| ITGA8 | integrin, alpha 8 | -0.0059851 |
| ATP7A | ATPase, Cu++ transporting, alpha polypeptide | -0.00597356 |
| CST7 | cystatin F (leukocystatin) | -0.00593205 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00592301 |
| PERP | PERP, TP53 apoptosis effector | -0.00592134 |
| CREBBP | CREB binding protein | -0.00591596 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.00591318 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | -0.00588101 |
| PDGFC | platelet derived growth factor C | -0.00587579 |
| TMEM41B | transmembrane protein 41B | -0.00584682 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -0.00582017 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00580356 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | -0.00579522 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | -0.00577252 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | -0.0057675 |
| UPK1A | uroplakin 1A | -0.00571479 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.00569603 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0056819 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00567202 |
| FBXW12 | F-box and WD repeat domain containing 12 | -0.00566796 |
| ZNF562 | zinc finger protein 562 | -0.00566152 |
| ZNF430 | zinc finger protein 430 | -0.00563705 |
| SPCS3 | signal peptidase complex subunit 3 homolog (S. cerevisiae) | -0.0056297 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | -0.0056105 |
| MAOA | monoamine oxidase A | -0.00558769 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.00557281 |
| CAMP | cathelicidin antimicrobial peptide | -0.00556051 |
| TSPOAP1 | TSPO associated protein 1 | -0.00552768 |
| CUX1 | cut-like homeobox 1 | -0.00552365 |
| KLHL21 | kelch-like family member 21 | -0.00551101 |
| DBN1 | drebrin 1 | -0.00550466 |
| NRIP3 | nuclear receptor interacting protein 3 | -0.00549899 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.00549293 |
| STK38 | serine/threonine kinase 38 | -0.0054853 |
| CHIT1 | chitinase 1 (chitotriosidase) | -0.00545802 |
| LDHB | lactate dehydrogenase B | -0.0054533 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00543622 |
| ACAN | aggrecan | -0.00543435 |
| EREG | epiregulin | -0.00543135 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | -0.00542713 |
| GRK2 | G protein-coupled receptor kinase 2 | -0.00541975 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | -0.00541017 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | -0.00539562 |
| CLCN3 | chloride channel, voltage-sensitive 3 | -0.00539113 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | -0.00538892 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | -0.00538262 |
| TMEM63A | transmembrane protein 63A | -0.00538118 |
| DBF4 | DBF4 zinc finger | -0.00537482 |
| RAG1 | recombination activating gene 1 | -0.00537266 |
| ELOB | elongin B | -0.0053611 |
| GSAP | gamma-secretase activating protein | -0.00533902 |
| AGO3 | argonaute RISC catalytic component 3 | -0.00532752 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.00532699 |
| METTL5 | methyltransferase like 5 | -0.00532281 |
| CADM1 | cell adhesion molecule 1 | -0.00531964 |
| SPRR2B | small proline-rich protein 2B | -0.0053145 |
| TUFT1 | tuftelin 1 | -0.00531148 |
| ATP5ME | ATP synthase membrane subunit e | -0.00530468 |
| PCP4 | Purkinje cell protein 4 | -0.00530352 |
| TSPYL5 | TSPY-like 5 | -0.00528535 |
| SUCO | SUN domain containing ossification factor | -0.00528161 |
| TOB1 | transducer of ERBB2, 1 | -0.00527847 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.00527835 |
| PPL | periplakin | -0.0052648 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.00525175 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.00524498 |
| TP73-AS1 | TP73 antisense RNA 1 | -0.00524203 |
| ZC3H4 | zinc finger CCCH-type containing 4 | -0.00523861 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.00523155 |
| HMGN3 | high mobility group nucleosomal binding domain 3 | -0.00522105 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.00521984 |
| AHSP | alpha hemoglobin stabilizing protein | -0.00521345 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00520837 |
| GOLPH3L | golgi phosphoprotein 3-like | -0.00520568 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | -0.00520565 |
| CROCCP2 | ciliary rootlet coiled-coil, rootletin pseudogene 2 | -0.00519404 |
| NOTCH2NL | notch 2 N-terminal like | -0.00519113 |
| NUTF2 | nuclear transport factor 2 | -0.00517971 |
| RBBP5 | retinoblastoma binding protein 5 | -0.00517883 |
| NDRG3 | NDRG family member 3 | -0.00514649 |
| ING3 | inhibitor of growth family, member 3 | -0.00514634 |
| GPSM2 | G-protein signaling modulator 2 | -0.00513545 |
| ZNF124 | zinc finger protein 124 | -0.00513188 |
| ZNF264 | zinc finger protein 264 | -0.00512598 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00511483 |
| CD84 | CD84 molecule | -0.00511158 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.00510737 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | -0.00510702 |
| MSMO1 | methylsterol monooxygenase 1 | -0.00510698 |
| AMPD3 | adenosine monophosphate deaminase 3 | -0.00509255 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | -0.00509153 |
| MRPL9 | mitochondrial ribosomal protein L9 | -0.00507487 |
| FCMR | Fc fragment of IgM receptor | -0.0050722 |
| ZNHIT1 | zinc finger, HIT-type containing 1 | -0.00506021 |
| KIAA0226L | KIAA0226-like | -0.00505705 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | -0.00503779 |
| MID1 | midline 1 | -0.00503412 |
| S100A9 | S100 calcium binding protein A9 | -0.00502971 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.00501306 |
| BBX | bobby sox homolog (Drosophila) | -0.00500759 |
| PTK2B | protein tyrosine kinase 2 beta | -0.00500392 |
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 | -0.00499616 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | -0.00499047 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | -0.00499022 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.00498924 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | -0.00496717 |
| RAB13 | RAB13, member RAS oncogene family | -0.00496247 |
| TCF3 | transcription factor 3 | -0.00495821 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | -0.0049514 |
| NVL | nuclear VCP-like | -0.00494887 |
| CRLF1 | cytokine receptor-like factor 1 | -0.00494727 |
| BGN | biglycan | -0.00494083 |
| RPS17 | ribosomal protein S17 | -0.00493828 |
| RIC8A | RIC8 guanine nucleotide exchange factor A | -0.00493015 |
| LUZP1 | leucine zipper protein 1 | -0.00492952 |
| WWC3 | WWC family member 3 | -0.00492131 |
| AIF1 | allograft inflammatory factor 1 | -0.00492004 |
| TP63 | tumor protein p63 | -0.00491619 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) | -0.00491589 |
| PTN | pleiotrophin | -0.00491188 |
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) | -0.00491142 |
| CD163 | CD163 molecule | -0.00490506 |
| TMEM159 | transmembrane protein 159 | -0.0049034 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 | -0.00489921 |
| BPIFA1 | BPI fold containing family A, member 1 | -0.00489672 |
| SKI | SKI proto-oncogene | -0.0048932 |
| RHCG | Rh family, C glycoprotein | -0.00487743 |
| FOXC1 | forkhead box C1 | -0.00487213 |
