RUNX3 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description runt-related transcription factor 3|This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 864)
External Link https://ncbi.nlm.nih.gov/gene/864
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Genes

499 genes differentially expressed following the RUNX3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CA2 carbonic anhydrase II 0.0138193
ARID4A AT rich interactive domain 4A (RBP1-like) 0.0119331
TM9SF3 transmembrane 9 superfamily member 3 0.011628
NMU neuromedin U 0.0112365
CD40 CD40 molecule, TNF receptor superfamily member 5 0.0112248
SEPP1 selenoprotein P, plasma, 1 0.0110951
FABP7 fatty acid binding protein 7, brain 0.010802
ACAT2 acetyl-CoA acetyltransferase 2 0.0105029
SELENBP1 selenium binding protein 1 0.0104398
LYZ lysozyme 0.0101006
SIRT3 sirtuin 3 0.0100006
JCHAIN joining chain of multimeric IgA and IgM 0.0096836
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.00948789
CFI complement factor I 0.00946982
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.0094216
MSMO1 methylsterol monooxygenase 1 0.00934357
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.00916874
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.00914572
DHCR24 24-dehydrocholesterol reductase 0.00907499
NDFIP1 Nedd4 family interacting protein 1 0.00905599
SST somatostatin 0.00898489
ATAD2 ATPase family, AAA domain containing 2 0.00894465
DEFB1 defensin, beta 1 0.00893389
CETN2 centrin, EF-hand protein, 2 0.0088614
TPM4 tropomyosin 4 0.00878273
GLO1 glyoxalase I 0.00864883
NPTX2 neuronal pentraxin II 0.00848608
IFITM1 interferon induced transmembrane protein 1 0.00848136
IFITM3 interferon induced transmembrane protein 3 0.00844362
MEIS2 Meis homeobox 2 0.00843654
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00837827
FOXG1 forkhead box G1 0.00831593
RAD54B RAD54 homolog B (S. cerevisiae) 0.00828325
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.00827865
PSAT1 phosphoserine aminotransferase 1 0.00827528
TRMT5 tRNA methyltransferase 5 0.00825623
PTK2 protein tyrosine kinase 2 0.00808239
PRDX2 peroxiredoxin 2 0.008074
TRAM1 translocation associated membrane protein 1 0.00807392
SORD sorbitol dehydrogenase 0.00801865
FOXF1 forkhead box F1 0.00799914
CDC42 cell division cycle 42 0.00796392
NQO1 NAD(P)H dehydrogenase, quinone 1 0.00795649
RAB20 RAB20, member RAS oncogene family 0.00792441
PLK1 polo-like kinase 1 0.00785908
CCNA2 cyclin A2 0.0077609
COL1A2 collagen, type I, alpha 2 0.00774413
EIF5A eukaryotic translation initiation factor 5A 0.00772842
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.00771684
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.00768708
TSPAN6 tetraspanin 6 0.00768145
ARMCX2 armadillo repeat containing, X-linked 2 0.00766669
ADCY3 adenylate cyclase 3 0.00762527
NUSAP1 nucleolar and spindle associated protein 1 0.00755377
PLP1 proteolipid protein 1 0.00754985
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 0.00754857
FCGBP Fc fragment of IgG binding protein 0.0075358
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 0.0074598
TCF21 transcription factor 21 0.00742809
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.00740746
MDFIC MyoD family inhibitor domain containing 0.0074027
P3H2 prolyl 3-hydroxylase 2 0.00739154
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.00738846
GDI2 GDP dissociation inhibitor 2 0.00735773
HAMP hepcidin antimicrobial peptide 0.00735082
SPON1 spondin 1, extracellular matrix protein 0.00733692
PDZD2 PDZ domain containing 2 0.0072396
DIRAS3 DIRAS family, GTP-binding RAS-like 3 0.00722738
CXCL12 chemokine (C-X-C motif) ligand 12 0.00720572
PON2 paraoxonase 2 0.00718187
COL6A2 collagen, type VI, alpha 2 0.00717202
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.00714142
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.007137
INSIG1 insulin induced gene 1 0.00713698
CPE carboxypeptidase E 0.00712277
SUB1 SUB1 homolog (S. cerevisiae) 0.00712027
ANOS1 anosmin 1 0.00711935
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein 0.00708427
DUT deoxyuridine triphosphatase 0.00707689
GAP43 growth associated protein 43 0.00704437
NES nestin 0.00700679
DEPDC1 DEP domain containing 1 0.00700244
PSIP1 PC4 and SFRS1 interacting protein 1 0.00699725
H1-10 H1.10 linker histone 0.0069548
GPR65 G protein-coupled receptor 65 0.00692652
LACTB2 lactamase, beta 2 0.0069164
H2AX H2A.X variant histone 0.0068943
KIF11 kinesin family member 11 0.00689083
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.00688538
DPYSL3 dihydropyrimidinase-like 3 0.00688106
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) 0.00686909
CADM1 cell adhesion molecule 1 0.00686103
PBK PDZ binding kinase 0.00685409
HHEX hematopoietically expressed homeobox 0.00680522
HOPX HOP homeobox 0.00678093
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.00677462
LAMP5 lysosomal-associated membrane protein family, member 5 0.00676851
COMMD10 COMM domain containing 10 0.00676115
KIF5C kinesin family member 5C 0.00674386
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.00674197
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 0.00673714
ACP3 acid phosphatase 3 0.00672913
CHEK2 checkpoint kinase 2 0.00670522
TNNT1 troponin T type 1 (skeletal, slow) 0.00663692
ERLIN2 ER lipid raft associated 2 0.00663348
HSDL2 hydroxysteroid dehydrogenase like 2 0.00662949
NLRP2 NLR family, pyrin domain containing 2 0.00661165
EPAS1 endothelial PAS domain protein 1 0.00660518
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.00659566
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.00658343
FANCG Fanconi anemia, complementation group G 0.00656801
MAT2B methionine adenosyltransferase II, beta 0.00656499
CALR calreticulin 0.00656454
WFDC2 WAP four-disulfide core domain 2 0.00656006
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.00652347
NBL1 neuroblastoma 1, DAN family BMP antagonist 0.00652344
MT1E metallothionein 1E 0.00650917
RTN1 reticulon 1 0.00650895
RCN2 reticulocalbin 2, EF-hand calcium binding domain 0.00650597
IDI1 isopentenyl-diphosphate delta isomerase 1 0.00649963
STOML2 stomatin (EPB72)-like 2 0.00648292
STMN2 stathmin 2 0.00648106
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.00647467
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 0.00647246
MSH2 mutS homolog 2 0.00646198
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.00645112
ATP5F1C ATP synthase F1 subunit gamma 0.00642422
DOK5 docking protein 5 0.00642377
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.00641996
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.00639308
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa 0.00634642
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase 0.00632885
CCNE2 cyclin E2 0.00632656
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 0.00630682
IL10RB interleukin 10 receptor, beta 0.00629659
MEN1 multiple endocrine neoplasia I 0.00629034
AURKB aurora kinase B 0.00627823
LGALS1 lectin, galactoside-binding, soluble, 1 0.00626482
MSLN mesothelin 0.00624585
NPY neuropeptide Y 0.00623944
EXOC5 exocyst complex component 5 0.00622655
LEPR leptin receptor 0.00621065
TMSB15A thymosin beta 15a 0.00618793
FLRT3 fibronectin leucine rich transmembrane protein 3 0.00618568
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 0.00618514
TYRO3 TYRO3 protein tyrosine kinase 0.00618482
MNDA myeloid cell nuclear differentiation antigen 0.00615651
STOM stomatin 0.00614858
C1QA complement component 1, q subcomponent, A chain 0.00613278
ASF1B anti-silencing function 1B histone chaperone 0.00613185
GET1 guided entry of tail-anchored proteins factor 1 0.00612125
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.00611876
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.00611215
FTO fat mass and obesity associated 0.00611204
DYNLT3 dynein, light chain, Tctex-type 3 0.00609756
RBM38 RNA binding motif protein 38 0.00608383
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.00607403
BST2 bone marrow stromal cell antigen 2 0.00607218
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.00606684
CPVL carboxypeptidase, vitellogenic-like 0.00606284
GOLM1 golgi membrane protein 1 0.00605952
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 0.00605769
HSPA8 heat shock 70kDa protein 8 0.00604841
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 0.00604663
GEMIN2 gem (nuclear organelle) associated protein 2 0.00604037
CD99 CD99 molecule 0.00603573
TSPAN8 tetraspanin 8 0.00603218
ANXA6 annexin A6 0.00602104
COL6A1 collagen, type VI, alpha 1 0.00602086
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.00601058
DHCR7 7-dehydrocholesterol reductase 0.00600652
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.00600262
RUVBL1 RuvB-like AAA ATPase 1 0.00599841
MAGEH1 melanoma antigen family H1 0.00598084
PDE4B phosphodiesterase 4B, cAMP-specific 0.0059797
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.00597777
SUSD4 sushi domain containing 4 0.00596738
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.00596602
RPA3 replication protein A3, 14kDa 0.00592358
IFITM2 interferon induced transmembrane protein 2 0.0059126
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 0.00591003
HMGB2 high mobility group box 2 0.00590896
GNAS GNAS complex locus 0.00590669
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 0.00590279
BMPR1A bone morphogenetic protein receptor, type IA 0.00589989
PEG3 paternally expressed 3 0.00589555
MYBPC1 myosin binding protein C, slow type 0.00587358
TSPAN13 tetraspanin 13 0.00586797
RHOA ras homolog family member A 0.00586713
NIBAN1 niban apoptosis regulator 1 0.0058656
CA11 carbonic anhydrase XI 0.00586549
DAZAP2 DAZ associated protein 2 0.00584795
HOXB6 homeobox B6 0.00582676
GINS1 GINS complex subunit 1 (Psf1 homolog) 0.00581765
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.00581259
TMEM230 transmembrane protein 230 0.00580087
MOCS2 molybdenum cofactor synthesis 2 0.00579866
TFDP1 transcription factor Dp-1 0.00579386
LAPTM5 lysosomal protein transmembrane 5 0.0057932
TMEM254 transmembrane protein 254 0.00577862
PSRC1 proline/serine-rich coiled-coil 1 0.0057746
NIPSNAP2 nipsnap homolog 2 0.00577429
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 0.00576913
RNASET2 ribonuclease T2 0.00576134
POT1 protection of telomeres 1 0.00575192
STK17A serine/threonine kinase 17a 0.00574797
TMEM14B transmembrane protein 14B 0.00574498
PRF1 perforin 1 (pore forming protein) 0.00574259
MAGT1 magnesium transporter 1 0.0057375
ADI1 acireductone dioxygenase 1 0.00573042
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase 0.00573005
TUBA1A tubulin, alpha 1a 0.00571882
CNOT8 CCR4-NOT transcription complex, subunit 8 0.00571857
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 0.00571653
GPM6B glycoprotein M6B 0.00569213
CTSC cathepsin C 0.00569142
SMC2 structural maintenance of chromosomes 2 0.00569075
RNASEH2A ribonuclease H2, subunit A 0.00568902
GSTM3 glutathione S-transferase mu 3 (brain) 0.00567959
TCTN3 tectonic family member 3 0.00567802
DCXR dicarbonyl/L-xylulose reductase 0.00567479
TLR3 toll-like receptor 3 0.00567277
MPP1 membrane protein, palmitoylated 1, 55kDa 0.00567159
YME1L1 YME1-like 1 ATPase 0.00566721
FOLR1 folate receptor 1 (adult) 0.00566401
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) 0.00565878
DHDDS dehydrodolichyl diphosphate synthase 0.00564926
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.00564779
ACSF2 acyl-CoA synthetase family member 2 0.00564259
TPX2 TPX2, microtubule-associated 0.00564132
ZDHHC4 zinc finger, DHHC-type containing 4 0.00562179
GPM6A glycoprotein M6A 0.00562053
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.00561494
PGD phosphogluconate dehydrogenase 0.0056128
P4HB prolyl 4-hydroxylase, beta polypeptide 0.00560042
NRGN neurogranin (protein kinase C substrate, RC3) 0.00559051
BIRC5 baculoviral IAP repeat containing 5 0.00558687
SCAMP1 secretory carrier membrane protein 1 0.00558195
DCK deoxycytidine kinase 0.00557255
NDP Norrie disease (pseudoglioma) 0.00556599
TMOD1 tropomodulin 1 0.00556416
DLK1 delta-like 1 homolog (Drosophila) 0.00555992
ACTB actin, beta 0.00555479
ARG2 arginase 2 0.00555307
B3GNT1 0.00554867
OAZ1 ornithine decarboxylase antizyme 1 0.00554109
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.00552939
HAUS4 HAUS augmin-like complex, subunit 4 0.00550925
CCK cholecystokinin 0.00549674
RNF130 ring finger protein 130 0.00549175

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0203952
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.015917
APOD apolipoprotein D -0.0152027
SCGB2A2 secretoglobin, family 2A, member 2 -0.0138764
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha -0.0133589
S100A9 S100 calcium binding protein A9 -0.0119842
SCGB1D2 secretoglobin, family 1D, member 2 -0.0117626
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -0.0117334
TOX3 TOX high mobility group box family member 3 -0.0116304
TIMP3 TIMP metallopeptidase inhibitor 3 -0.011616
FABP4 fatty acid binding protein 4, adipocyte -0.0111701
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -0.0109365
KRT14 keratin 14, type I -0.0109248
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.0106578
BTG1 B-cell translocation gene 1, anti-proliferative -0.0103849
GADD45A growth arrest and DNA-damage-inducible, alpha -0.0103767
IPO13 importin 13 -0.0103222
BRD2 bromodomain containing 2 -0.0100687
LAMC2 laminin, gamma 2 -0.0100037
S100A12 S100 calcium binding protein A12 -0.00981364
DUSP6 dual specificity phosphatase 6 -0.00972138
INHBA inhibin, beta A -0.00951272
S100A8 S100 calcium binding protein A8 -0.00911608
MTUS1 microtubule associated tumor suppressor 1 -0.00894372
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.00891468
NUPR1 nuclear protein, transcriptional regulator, 1 -0.0088513
MGP matrix Gla protein -0.00838859
SMAD7 SMAD family member 7 -0.00837869
DSP desmoplakin -0.00835791
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00824453
AKR1C1 aldo-keto reductase family 1, member C1 -0.00821981
CIAO3 cytosolic iron-sulfur assembly component 3 -0.00819717
PCDH9 protocadherin 9 -0.00818565
HSPA1A heat shock 70kDa protein 1A -0.00818495
S100P S100 calcium binding protein P -0.00817053
CCL20 chemokine (C-C motif) ligand 20 -0.00810824
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -0.00809484
COMP cartilage oligomeric matrix protein -0.00804673
SAFB2 scaffold attachment factor B2 -0.00804256
MMP9 matrix metallopeptidase 9 -0.0078996
AKR1C2 aldo-keto reductase family 1, member C2 -0.00782547
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.00780634
RRAGD Ras-related GTP binding D -0.00776305
BRD4 bromodomain containing 4 -0.00775481
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.00770886
GPNMB glycoprotein (transmembrane) nmb -0.00768912
NPIPA1 nuclear pore complex interacting protein family, member A1 -0.00763207
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -0.00760687
MYLIP myosin regulatory light chain interacting protein -0.00755473
CCL19 chemokine (C-C motif) ligand 19 -0.0075509
HIP1R huntingtin interacting protein 1 related -0.00753751
TNC tenascin C -0.00751856
DPEP1 dipeptidase 1 (renal) -0.00751779
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00751758
MAGEA3 melanoma antigen family A3 -0.00748677
CEL carboxyl ester lipase -0.00747437
ZNF281 zinc finger protein 281 -0.0074486
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 -0.00743906
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -0.00742787
NT5E 5'-nucleotidase, ecto (CD73) -0.00742489
CD36 CD36 molecule (thrombospondin receptor) -0.00739423
SNAI2 snail family zinc finger 2 -0.00735776
TSC22D2 TSC22 domain family, member 2 -0.00732259
CLCN7 chloride channel, voltage-sensitive 7 -0.00731385
HOXC10 homeobox C10 -0.00727884
SCGB2A1 secretoglobin, family 2A, member 1 -0.00727877
CA12 carbonic anhydrase XII -0.007258
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.00724687
GLOD4 glyoxalase domain containing 4 -0.00724444
RABEP2 rabaptin, RAB GTPase binding effector protein 2 -0.00720574
RRAGC Ras-related GTP binding C -0.00714453
KRT15 keratin 15, type I -0.00713303
NOTCH1 notch 1 -0.00712082
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G -0.00711347
KRT6A keratin 6A, type II -0.00707643
MYH11 myosin, heavy chain 11, smooth muscle -0.00707356
CYFIP2 cytoplasmic FMR1 interacting protein 2 -0.00704886
CCL21 chemokine (C-C motif) ligand 21 -0.00703899
NOP53 NOP53 ribosome biogenesis factor -0.00702066
PRAME preferentially expressed antigen in melanoma -0.0070166
MIR22HG MIR22 host gene -0.00699761
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.0069887
SWAP70 SWAP switching B-cell complex 70kDa subunit -0.00696232
KRT23 keratin 23, type I -0.00695009
FNDC3B fibronectin type III domain containing 3B -0.00694007
PLA1A phospholipase A1 member A -0.00693131
CUX1 cut-like homeobox 1 -0.00691267
LEF1 lymphoid enhancer-binding factor 1 -0.00686393
MFAP5 microfibrillar associated protein 5 -0.00685059
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.00682852
ENAH enabled homolog (Drosophila) -0.0068188
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 -0.00680338
TPSAB1 tryptase alpha/beta 1 -0.00671267
TGFBI transforming growth factor, beta-induced, 68kDa -0.00669117
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -0.00667455
MMP1 matrix metallopeptidase 1 -0.00666969
DUSP4 dual specificity phosphatase 4 -0.00663432
PELI1 pellino E3 ubiquitin protein ligase 1 -0.00658507
AGR2 anterior gradient 2 -0.00658429
KLHL24 kelch-like family member 24 -0.0065639
POSTN periostin, osteoblast specific factor -0.00655706
MAP7 microtubule-associated protein 7 -0.00652935
SCPEP1 serine carboxypeptidase 1 -0.0065272
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00651744
RGS16 regulator of G-protein signaling 16 -0.00650733
SLIT1 slit homolog 1 (Drosophila) -0.00647713
ISG20 interferon stimulated exonuclease gene 20kDa -0.00646363
KMT5B lysine methyltransferase 5B -0.00645656
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 -0.00645572
ELOB elongin B -0.00643103
LUC7L LUC7-like (S. cerevisiae) -0.00642937
ZCCHC8 zinc finger, CCHC domain containing 8 -0.0064178
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 -0.00640094
TULP4 tubby like protein 4 -0.00637468
DUSP7 dual specificity phosphatase 7 -0.00637221
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00634705
EPS8 epidermal growth factor receptor pathway substrate 8 -0.00634443
EIF6 eukaryotic translation initiation factor 6 -0.00633171
REXO2 RNA exonuclease 2 -0.00632026
SAMD4A sterile alpha motif domain containing 4A -0.00631852
TPST1 tyrosylprotein sulfotransferase 1 -0.00631654
GREM1 gremlin 1, DAN family BMP antagonist -0.00630468
CTSD cathepsin D -0.00629893
VCAN versican -0.00628422
MAPKBP1 mitogen-activated protein kinase binding protein 1 -0.00626936
CRISP3 cysteine-rich secretory protein 3 -0.00622364
EIF5B eukaryotic translation initiation factor 5B -0.00622224
CAST calpastatin -0.00620968
ASPN asporin -0.00620715
IL6R interleukin 6 receptor -0.0062039
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -0.00620236
CFP complement factor properdin -0.00620075
MINK1 misshapen-like kinase 1 -0.0061994
AP3D1 adaptor-related protein complex 3, delta 1 subunit -0.0061567
COL15A1 collagen, type XV, alpha 1 -0.00615321
CTSA cathepsin A -0.00614817
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00613825
SYNE1 spectrin repeat containing, nuclear envelope 1 -0.00612796
NDRG1 N-myc downstream regulated 1 -0.00611882
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.00611484
HOXC6 homeobox C6 -0.00610802
AZU1 azurocidin 1 -0.00605883
MITF microphthalmia-associated transcription factor -0.00603449
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.00603218
ANKRD11 ankyrin repeat domain 11 -0.00600507
LIMS1 LIM and senescent cell antigen-like domains 1 -0.00598645
NAA60 N(alpha)-acetyltransferase 60, NatF catalytic subunit -0.00598241
PLXNA1 plexin A1 -0.00596693
GOLGA8A golgin A8 family, member A -0.00595865
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) -0.00595848
PTPRD protein tyrosine phosphatase, receptor type, D -0.00595107
PNN pinin, desmosome associated protein -0.00594227
AKAP8 A kinase (PRKA) anchor protein 8 -0.00592426
ZBTB7A zinc finger and BTB domain containing 7A -0.00591852
F5 coagulation factor V (proaccelerin, labile factor) -0.00591526
PLCB4 phospholipase C, beta 4 -0.00590304
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene -0.00589518
OSR2 odd-skipped related transciption factor 2 -0.00589289
SFRP4 secreted frizzled-related protein 4 -0.00589177
IER5 immediate early response 5 -0.00588749
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 -0.00582781
CD9 CD9 molecule -0.00581943
MID1 midline 1 -0.00581153
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00580889
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 -0.00580495
SFN stratifin -0.0058018
NAV2 neuron navigator 2 -0.00579624
TFF3 trefoil factor 3 (intestinal) -0.00579447
LONP2 lon peptidase 2, peroxisomal -0.00578304
NCOR2 nuclear receptor corepressor 2 -0.00578263
SAT1 spermidine/spermine N1-acetyltransferase 1 -0.0057767
LIPG lipase, endothelial -0.00576723
STK26 serine/threonine protein kinase 26 -0.00576112
MED13 mediator complex subunit 13 -0.00575142
KRT5 keratin 5, type II -0.00574552
MYO6 myosin VI -0.00573537
NME3 NME/NM23 nucleoside diphosphate kinase 3 -0.00572462
CTSG cathepsin G -0.00572334
SQSTM1 sequestosome 1 -0.00572169
ELF5 E74-like factor 5 (ets domain transcription factor) -0.00572099
LRP4 low density lipoprotein receptor-related protein 4 -0.00571387
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -0.0056942
POLR1D polymerase (RNA) I polypeptide D, 16kDa -0.00567961
QPCT glutaminyl-peptide cyclotransferase -0.00567356
THBS1 thrombospondin 1 -0.0056628
TXLNA taxilin alpha -0.00565008
VEGFA vascular endothelial growth factor A -0.00564963
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B -0.00563304
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 -0.00562764
UQCRH ubiquinol-cytochrome c reductase hinge protein -0.00562573
MFAP3L microfibrillar-associated protein 3-like -0.00561293
ARID5B AT rich interactive domain 5B (MRF1-like) -0.00560359
CXCL3 chemokine (C-X-C motif) ligand 3 -0.00559778
FTSJ3 FtsJ homolog 3 (E. coli) -0.00559052
TPP2 tripeptidyl peptidase II -0.0055904
JARID2 jumonji, AT rich interactive domain 2 -0.00558927
MGLL monoglyceride lipase -0.00558107
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase -0.00557398
MMP19 matrix metallopeptidase 19 -0.00556965
ATG3 autophagy related 3 -0.00555932
ARID4B AT rich interactive domain 4B (RBP1-like) -0.00555888
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast) -0.00555716
NOTCH3 notch 3 -0.00555238
WASL Wiskott-Aldrich syndrome-like -0.00554898
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 -0.00551647
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) -0.00551307
FXR1 fragile X mental retardation, autosomal homolog 1 -0.00550706
MYH9 myosin, heavy chain 9, non-muscle -0.00549528
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -0.00547338
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.00546796
UXT ubiquitously-expressed, prefoldin-like chaperone -0.00544382
KRT6B keratin 6B, type II -0.00544306
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.00543672
VTN vitronectin -0.00543333
BAG3 BCL2-associated athanogene 3 -0.00542492
DAAM1 dishevelled associated activator of morphogenesis 1 -0.00541602
SART1 squamous cell carcinoma antigen recognized by T cells -0.00541381
ERG v-ets avian erythroblastosis virus E26 oncogene homolog -0.00538912
ITGA6 integrin, alpha 6 -0.00538824
NBPF10 neuroblastoma breakpoint family, member 10 -0.00538329
RUBCN rubicon autophagy regulator -0.00538101
EP300 E1A binding protein p300 -0.00537811
CLEC3B C-type lectin domain family 3, member B -0.00537734
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 -0.00537576
PFDN2 prefoldin subunit 2 -0.00537091
PMP22 peripheral myelin protein 22 -0.00536036
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 -0.00535856
SIKE1 suppressor of IKBKE 1 -0.00535389
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 -0.00535065
SF3B2 splicing factor 3b, subunit 2, 145kDa -0.00534018
ECM1 extracellular matrix protein 1 -0.00533969
PRRC2C proline-rich coiled-coil 2C -0.00533733
LAMB3 laminin, beta 3 -0.0053349
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00532377
TRIM29 tripartite motif containing 29 -0.00531927
CEP350 centrosomal protein 350kDa -0.00531852
DCLK1 doublecortin-like kinase 1 -0.00531506
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 -0.00531388
IGF2R insulin-like growth factor 2 receptor -0.00531311
COL7A1 collagen, type VII, alpha 1 -0.00530677
RAI14 retinoic acid induced 14 -0.00530441
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) -0.00530151
SOX4 SRY (sex determining region Y)-box 4 -0.0052994
MCM2 minichromosome maintenance complex component 2 -0.00529914
EHD1 EH-domain containing 1 -0.00529787
PUM1 pumilio RNA-binding family member 1 -0.00529527
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 -0.00528554
AEBP1 AE binding protein 1 -0.00527716
USP47 ubiquitin specific peptidase 47 -0.00527305