RXRA Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description retinoid X receptor, alpha|Retinoid X receptors (RXRs) and retinoic acid receptors (RARs) are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors function as transcription factors by binding as homodimers or heterodimers to specific sequences in the promoters of target genes. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014] (NCBI Entrez Gene Database, 6256)
External Link https://ncbi.nlm.nih.gov/gene/6256
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Genes

499 genes differentially expressed following the RXRA gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.0189999
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.0116794
SPINT2 serine peptidase inhibitor, Kunitz type, 2 0.0102854
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.0102179
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.00932118
TARP TCR gamma alternate reading frame protein 0.00929708
EPCAM epithelial cell adhesion molecule 0.00929146
TGM2 transglutaminase 2 0.00912539
FBP1 fructose-1,6-bisphosphatase 1 0.00911957
TACSTD2 tumor-associated calcium signal transducer 2 0.00909176
RAD23B RAD23 homolog B (S. cerevisiae) 0.00883083
SPTSSA serine palmitoyltransferase, small subunit A 0.00877235
PCP4 Purkinje cell protein 4 0.00870836
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.00865533
CST3 cystatin C 0.00850263
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00837515
KDM5D lysine (K)-specific demethylase 5D 0.00829783
ANXA3 annexin A3 0.00809861
CTSH cathepsin H 0.00804588
SLC44A4 solute carrier family 44, member 4 0.00803843
IFI6 interferon, alpha-inducible protein 6 0.00802477
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 0.00788287
CD9 CD9 molecule 0.00786149
SH3YL1 SH3 and SYLF domain containing 1 0.00778605
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 0.00775021
RAB25 RAB25, member RAS oncogene family 0.00773592
TSPAN8 tetraspanin 8 0.00772769
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.00772511
MSMB microseminoprotein, beta- 0.00765615
ANOS1 anosmin 1 0.00764778
LTF lactotransferrin 0.00759772
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 0.00755071
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 0.00747897
RPS4Y1 ribosomal protein S4, Y-linked 1 0.00747714
SFTPB surfactant protein B 0.00747012
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 0.00746449
PHACTR2 phosphatase and actin regulator 2 0.00741077
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.00738892
TPD52L1 tumor protein D52-like 1 0.00734356
CD2 CD2 molecule 0.00728298
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 0.00726524
NKX3-1 NK3 homeobox 1 0.00720597
EGR2 early growth response 2 0.00716116
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.00711875
SERINC5 serine incorporator 5 0.00704514
OLFM4 olfactomedin 4 0.00702526
RGS10 regulator of G-protein signaling 10 0.00697809
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 0.00692492
RRAGA Ras-related GTP binding A 0.00685645
APLP2 amyloid beta (A4) precursor-like protein 2 0.00684796
ASF1A anti-silencing function 1A histone chaperone 0.00683132
FGL2 fibrinogen-like 2 0.00682827
GREB1 growth regulation by estrogen in breast cancer 1 0.00672279
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.0067031
AGR2 anterior gradient 2 0.00668742
CADM1 cell adhesion molecule 1 0.00664532
PLN phospholamban 0.00661575
KYNU kynureninase 0.00658043
FYB1 FYN binding protein 1 0.00655886
LGALS2 lectin, galactoside-binding, soluble, 2 0.00655828
GSTT1 glutathione S-transferase theta 1 0.00652933
SFTPA2 surfactant protein A2 0.00646204
MMP1 matrix metallopeptidase 1 0.0063772
WDR7 WD repeat domain 7 0.00636925
KLK2 kallikrein-related peptidase 2 0.00634131
MAP7 microtubule-associated protein 7 0.00633168
FUCA1 fucosidase, alpha-L- 1, tissue 0.00629089
HLA-DMB major histocompatibility complex, class II, DM beta 0.00625227
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.00624205
CCR7 chemokine (C-C motif) receptor 7 0.00621999
CTSS cathepsin S 0.0062186
SLC25A46 solute carrier family 25, member 46 0.00620807
AKAP7 A kinase (PRKA) anchor protein 7 0.00616668
CCR2 chemokine (C-C motif) receptor 2 0.00615731
ENC1 ectodermal-neural cortex 1 (with BTB domain) 0.00615233
GUCY2C guanylate cyclase 2C 0.00615163
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.00615123
SFRP4 secreted frizzled-related protein 4 0.0061331
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.00612417
MLPH melanophilin 0.00611899
SH3BGRL SH3 domain binding glutamate-rich protein like 0.00607694
TSPYL5 TSPY-like 5 0.00607269
SELL selectin L 0.00606195
AMD1 adenosylmethionine decarboxylase 1 0.00605568
IFITM1 interferon induced transmembrane protein 1 0.00605223
COCH cochlin 0.00605027
MICU2 mitochondrial calcium uptake 2 0.00604206
GPX2 glutathione peroxidase 2 0.00601547
RFK riboflavin kinase 0.00600557
GRB14 growth factor receptor-bound protein 14 0.00599988
AMACR alpha-methylacyl-CoA racemase 0.00598247
TCEAL1 transcription elongation factor A (SII)-like 1 0.00595847
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 0.00594184
MNDA myeloid cell nuclear differentiation antigen 0.00588592
GZMK granzyme K (granzyme 3; tryptase II) 0.00588547
CCND2 cyclin D2 0.0058783
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.00583956
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.00583245
BASP1 brain abundant, membrane attached signal protein 1 0.0058269
CD52 CD52 molecule 0.00582521
SFTPD surfactant protein D 0.00581552
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 0.00580937
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.0057861
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 0.00578005
CKAP2 cytoskeleton associated protein 2 0.00575034
CDK19 cyclin-dependent kinase 19 0.00571584
SORBS2 sorbin and SH3 domain containing 2 0.00571511
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.0057035
SFTPC surfactant protein C 0.0057024
HACD1 3-hydroxyacyl-CoA dehydratase 1 0.00569061
PRKCZ protein kinase C, zeta 0.00568861
SIRT3 sirtuin 3 0.00568393
LGALS1 lectin, galactoside-binding, soluble, 1 0.00568256
CCR1 chemokine (C-C motif) receptor 1 0.00565963
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) 0.0056589
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 0.00565551
DHRS7 dehydrogenase/reductase (SDR family) member 7 0.00565078
SIDT2 SID1 transmembrane family, member 2 0.00561637
CYBB cytochrome b-245, beta polypeptide 0.00560392
LYZ lysozyme 0.00560094
TMSB15A thymosin beta 15a 0.00558849
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 0.005529
UBE2N ubiquitin-conjugating enzyme E2N 0.00551939
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.00546631
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.00546519
TCAF1 TRPM8 channel-associated factor 1 0.00545665
GTF2H5 general transcription factor IIH, polypeptide 5 0.00544727
IGSF6 immunoglobulin superfamily, member 6 0.00544588
TMEM106B transmembrane protein 106B 0.00544499
SEC23A Sec23 homolog A (S. cerevisiae) 0.0054446
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 0.00542941
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.00542877
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 0.00538535
REEP1 receptor accessory protein 1 0.00538344
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.00537448
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.00536338
CKS2 CDC28 protein kinase regulatory subunit 2 0.0053614
CST1 cystatin SN 0.00535897
AMH anti-Mullerian hormone 0.00535836
TIMP1 TIMP metallopeptidase inhibitor 1 0.00535616
TIGAR TP53 induced glycolysis regulatory phosphatase 0.0053463
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0053379
TFEC transcription factor EC 0.00532398
HBB hemoglobin, beta 0.00531674
AMIGO2 adhesion molecule with Ig-like domain 2 0.00530651
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 0.00529566
MMP12 matrix metallopeptidase 12 0.00529224
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.00529217
NRGN neurogranin (protein kinase C substrate, RC3) 0.0052806
ARMCX6 armadillo repeat containing, X-linked 6 0.00527841
TMEM165 transmembrane protein 165 0.00527542
THAP12 THAP domain containing 12 0.00526018
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 0.00522477
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.00522154
PRPF4 pre-mRNA processing factor 4 0.00521078
KLK3 kallikrein-related peptidase 3 0.00519713
IL2RG interleukin 2 receptor, gamma 0.0051957
CEMIP cell migration inducing protein, hyaluronan binding 0.00518443
NDNF neuron-derived neurotrophic factor 0.00517753
RWDD1 RWD domain containing 1 0.00517664
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.00512308
NFE2L3 nuclear factor, erythroid 2-like 3 0.0051143
CUX2 cut-like homeobox 2 0.00511013
ANGEL2 angel homolog 2 (Drosophila) 0.00509691
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.00508965
DYNLT3 dynein, light chain, Tctex-type 3 0.00508157
MYO5C myosin VC 0.00508012
ZNF184 zinc finger protein 184 0.00507948
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.00507581
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.00506378
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 0.00505475
HOXB13 homeobox B13 0.00505173
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.00504722
FRY furry homolog (Drosophila) 0.00504561
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.00504445
S100A10 S100 calcium binding protein A10 0.00504249
PFDN4 prefoldin subunit 4 0.00503199
THYN1 thymocyte nuclear protein 1 0.0050315
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 0.00502087
SAMHD1 SAM domain and HD domain 1 0.00501054
AQP4 aquaporin 4 0.00500873
ITK IL2-inducible T-cell kinase 0.00500791
ZNF226 zinc finger protein 226 0.00498556
CTSZ cathepsin Z 0.00496395
IFI30 interferon, gamma-inducible protein 30 0.00495564
PSD3 pleckstrin and Sec7 domain containing 3 0.00493086
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.00492327
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.0049214
MRPS28 mitochondrial ribosomal protein S28 0.00492056
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) 0.00490225
TFF1 trefoil factor 1 0.00489881
WWOX WW domain containing oxidoreductase 0.00488336
MARCO macrophage receptor with collagenous structure 0.00487814
MOCOS molybdenum cofactor sulfurase 0.00487528
CXCL11 chemokine (C-X-C motif) ligand 11 0.00487346
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.00487221
EPHB2 EPH receptor B2 0.00486551
CLEC7A C-type lectin domain family 7, member A 0.00485414
GRSF1 G-rich RNA sequence binding factor 1 0.00482696
QPCT glutaminyl-peptide cyclotransferase 0.00482655
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.0048209
LPXN leupaxin 0.00481453
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 0.00481168
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) 0.00481168
NRBF2 nuclear receptor binding factor 2 0.00480718
DENND1B DENN/MADD domain containing 1B 0.00478959
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.00478453
FZD5 frizzled class receptor 5 0.00477411
PRF1 perforin 1 (pore forming protein) 0.00474543
SEPHS1 selenophosphate synthetase 1 0.00474417
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.0047431
CNOT8 CCR4-NOT transcription complex, subunit 8 0.00473697
NKX2-1 NK2 homeobox 1 0.00473514
TMPRSS2 transmembrane protease, serine 2 0.0047285
GSTA4 glutathione S-transferase alpha 4 0.00472706
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 0.00472254
AKAP11 A kinase (PRKA) anchor protein 11 0.00471743
CHN2 chimerin 2 0.00471681
CCNB2 cyclin B2 0.00471209
INHBA inhibin, beta A 0.00471117
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00471099
CENPU centromere protein U 0.00470163
CD1E CD1e molecule 0.00469962
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant 0.00468511
EIF4E eukaryotic translation initiation factor 4E 0.00467973
GLO1 glyoxalase I 0.0046648
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.00466436
GATA6 GATA binding protein 6 0.00465606
FOLH1B folate hydrolase 1B 0.00462288
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 0.00461921
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.00460875
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.00460423
CD3D CD3d molecule, delta (CD3-TCR complex) 0.0045879
CCNI cyclin I 0.0045791
NCF2 neutrophil cytosolic factor 2 0.00457898
TSPAN6 tetraspanin 6 0.0045584
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.00453982
ANXA6 annexin A6 0.00453606
WWTR1 WW domain containing transcription regulator 1 0.00453045
AXL AXL receptor tyrosine kinase 0.00452802
RHOB ras homolog family member B 0.00452473
R3HDM2 R3H domain containing 2 0.00452332
OAZ3 ornithine decarboxylase antizyme 3 0.00452015
CLEC4A C-type lectin domain family 4, member A 0.00452008
TSPYL1 TSPY-like 1 0.0045188
DDHD2 DDHD domain containing 2 0.00451447
LST1 leukocyte specific transcript 1 0.00450835
SELENOT selenoprotein T 0.00450701
NPC2 Niemann-Pick disease, type C2 0.00450582
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 0.00450541

decreased expression

Symbol Name Standardized Value
HSPB1 heat shock 27kDa protein 1 -0.0205346
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.017595
CXCL14 chemokine (C-X-C motif) ligand 14 -0.0134785
ASS1 argininosuccinate synthase 1 -0.0126881
XIC X chromosome inactivation center -0.0124525
PEG10 paternally expressed 10 -0.0119937
KRT14 keratin 14, type I -0.011456
CRABP2 cellular retinoic acid binding protein 2 -0.0110164
ATF3 activating transcription factor 3 -0.0108925
LYPD1 LY6/PLAUR domain containing 1 -0.0106379
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.0104565
TXLNA taxilin alpha -0.0103225
S100A7 S100 calcium binding protein A7 -0.0103006
MT1E metallothionein 1E -0.0101589
SCGB2A1 secretoglobin, family 2A, member 1 -0.0100755
CSRP2 cysteine and glycine-rich protein 2 -0.0100741
ECM1 extracellular matrix protein 1 -0.00972313
CA12 carbonic anhydrase XII -0.0093472
PDZD2 PDZ domain containing 2 -0.00931271
DEFB1 defensin, beta 1 -0.00929287
SCGB2A2 secretoglobin, family 2A, member 2 -0.0091137
SSBP2 single-stranded DNA binding protein 2 -0.00898008
PELI1 pellino E3 ubiquitin protein ligase 1 -0.0089193
SCGB1D2 secretoglobin, family 1D, member 2 -0.00885734
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) -0.00879118
RND3 Rho family GTPase 3 -0.0086182
ANPEP alanyl (membrane) aminopeptidase -0.00859059
RGCC regulator of cell cycle -0.0085724
MT1X metallothionein 1X -0.0085378
TUBB2B tubulin, beta 2B class IIb -0.00845976
TRIM29 tripartite motif containing 29 -0.0083788
S100A9 S100 calcium binding protein A9 -0.00833103
DOK5 docking protein 5 -0.00829766
SGCE sarcoglycan, epsilon -0.008255
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -0.00821234
ZNF395 zinc finger protein 395 -0.00818999
CHN1 chimerin 1 -0.00808624
TUBB2A tubulin, beta 2A class IIa -0.0080758
MEIS1 Meis homeobox 1 -0.0080313
DAXX death-domain associated protein -0.00797913
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00792074
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -0.00791793
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 -0.00781038
PI3 peptidase inhibitor 3, skin-derived -0.00780555
CXCL8 chemokine (C-X-C motif) ligand 8 -0.00779791
KRT5 keratin 5, type II -0.00777266
FGB fibrinogen beta chain -0.00775489
KLK10 kallikrein-related peptidase 10 -0.0077439
MT1F metallothionein 1F -0.00770061
RGS16 regulator of G-protein signaling 16 -0.00760856
OPHN1 oligophrenin 1 -0.00756948
SST somatostatin -0.00756532
FCGBP Fc fragment of IgG binding protein -0.00753928
MGLL monoglyceride lipase -0.00753797
ALB albumin -0.00753079
MAGEA3 melanoma antigen family A3 -0.00747634
SPRR1A small proline-rich protein 1A -0.00746421
KLK5 kallikrein-related peptidase 5 -0.00743226
C3 complement component 3 -0.00740387
SPRR2B small proline-rich protein 2B -0.0073931
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -0.0073287
KLK7 kallikrein-related peptidase 7 -0.00729866
PITX3 paired-like homeodomain 3 -0.0072727
HSPA6 heat shock 70kDa protein 6 (HSP70B') -0.0072625
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) -0.00722766
RRAGD Ras-related GTP binding D -0.00721024
NES nestin -0.00716462
SCD5 stearoyl-CoA desaturase 5 -0.0071599
STC1 stanniocalcin 1 -0.00712383
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.00711079
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00696623
OXTR oxytocin receptor -0.00695596
TWIST1 twist family bHLH transcription factor 1 -0.00695156
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 -0.00692814
PDGFD platelet derived growth factor D -0.0069041
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 -0.00690197
HOXB2 homeobox B2 -0.00688931
BTG3 BTG family, member 3 -0.00686566
OLFML3 olfactomedin-like 3 -0.00686318
CLTB clathrin, light chain B -0.00681838
STC2 stanniocalcin 2 -0.00678447
ADIRF adipogenesis regulatory factor -0.00675894
PDZK1IP1 PDZK1 interacting protein 1 -0.00671288
MT1G metallothionein 1G -0.00669315
HSPA1A heat shock 70kDa protein 1A -0.00668725
TFPI2 tissue factor pathway inhibitor 2 -0.00667657
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -0.00662602
BEX1 brain expressed, X-linked 1 -0.00660332
SPRY4 sprouty homolog 4 (Drosophila) -0.00658207
KLK8 kallikrein-related peptidase 8 -0.00656572
SPRED2 sprouty-related, EVH1 domain containing 2 -0.00653176
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.00649865
GREM1 gremlin 1, DAN family BMP antagonist -0.00642413
PLK2 polo-like kinase 2 -0.00642215
CLDN10 claudin 10 -0.00641288
SOD2 superoxide dismutase 2, mitochondrial -0.00640984
CD248 CD248 molecule, endosialin -0.00638859
ALDOB aldolase B, fructose-bisphosphate -0.00638009
TP53BP2 tumor protein p53 binding protein 2 -0.00635892
ANKRD11 ankyrin repeat domain 11 -0.00635583
POU2AF1 POU class 2 associating factor 1 -0.00634492
MXRA5 matrix-remodelling associated 5 -0.00623994
ETFB electron-transfer-flavoprotein, beta polypeptide -0.0062272
CFB complement factor B -0.00615308
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -0.00614651
VNN1 vanin 1 -0.00613159
NOLC1 nucleolar and coiled-body phosphoprotein 1 -0.00611334
PODXL podocalyxin-like -0.00609342
SPRR1B small proline-rich protein 1B -0.00605797
HSPA2 heat shock 70kDa protein 2 -0.00602807
MUC16 mucin 16, cell surface associated -0.0060237
BHMT2 betaine--homocysteine S-methyltransferase 2 -0.00600058
GRB7 growth factor receptor-bound protein 7 -0.00598599
CLEC2B C-type lectin domain family 2, member B -0.00597997
FABP5 fatty acid binding protein 5 (psoriasis-associated) -0.00596554
MAGEA1 melanoma antigen family A1 -0.00596353
DIPK1A divergent protein kinase domain 1A -0.00594412
CBS cystathionine-beta-synthase -0.0059346
RTN2 reticulon 2 -0.00592707
EIF5 eukaryotic translation initiation factor 5 -0.00590623
TSPAN3 tetraspanin 3 -0.00587942
IL17RB interleukin 17 receptor B -0.00584812
EMX2 empty spiracles homeobox 2 -0.00582414
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -0.00580561
SLC43A3 solute carrier family 43, member 3 -0.00579216
DYNLL1 dynein, light chain, LC8-type 1 -0.0057668
EMP1 epithelial membrane protein 1 -0.00576361
FGL1 fibrinogen-like 1 -0.00574795
OLFML2A olfactomedin-like 2A -0.00571199
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked -0.005704
TPST1 tyrosylprotein sulfotransferase 1 -0.0056969
PLVAP plasmalemma vesicle associated protein -0.0056652
SWAP70 SWAP switching B-cell complex 70kDa subunit -0.00564344
MFSD10 major facilitator superfamily domain containing 10 -0.00564319
TENM3 teneurin transmembrane protein 3 -0.00564176
CALML3 calmodulin-like 3 -0.00563107
FLT1 fms-related tyrosine kinase 1 -0.00562052
NPR1 natriuretic peptide receptor 1 -0.00561501
TERT telomerase reverse transcriptase -0.00561494
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -0.00560807
LPPR4 lipid phosphate phosphatase-related protein type 4 -0.00559991
FBXL12 F-box and leucine-rich repeat protein 12 -0.00558987
KLK11 kallikrein-related peptidase 11 -0.00557973
KRT16 keratin 16, type I -0.00557306
PTN pleiotrophin -0.00557216
METTL7A methyltransferase like 7A -0.00555434
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 -0.00554737
AHCY adenosylhomocysteinase -0.00552701
ZFHX4 zinc finger homeobox 4 -0.00552603
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -0.0054852
PCDH17 protocadherin 17 -0.00548213
CTSG cathepsin G -0.00544385
C1S complement component 1, s subcomponent -0.0054067
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) -0.00540348
CX3CL1 chemokine (C-X3-C motif) ligand 1 -0.00540052
CRABP1 cellular retinoic acid binding protein 1 -0.00539357
SYNM synemin, intermediate filament protein -0.00537943
GRAMD2B GRAM domain containing 2B -0.00536921
CP ceruloplasmin (ferroxidase) -0.00536095
ANK2 ankyrin 2, neuronal -0.00535544
GBAP1 glucosidase, beta, acid pseudogene 1 -0.00535019
MEN1 multiple endocrine neoplasia I -0.00534585
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) -0.00531956
CRCT1 cysteine-rich C-terminal 1 -0.00531596
DDR2 discoidin domain receptor tyrosine kinase 2 -0.00531397
GPRC5B G protein-coupled receptor, class C, group 5, member B -0.00530889
PLS3 plastin 3 -0.00528222
ITM2C integral membrane protein 2C -0.00527752
GAS6 growth arrest-specific 6 -0.00521963
ZSCAN18 zinc finger and SCAN domain containing 18 -0.00520716
HSPB8 heat shock 22kDa protein 8 -0.00520377
ASCC2 activating signal cointegrator 1 complex subunit 2 -0.00519443
PCOLCE2 procollagen C-endopeptidase enhancer 2 -0.00518926
MID1 midline 1 -0.00518667
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 -0.00515529
CNN3 calponin 3, acidic -0.00515126
AKAP8 A kinase (PRKA) anchor protein 8 -0.00514438
KLK6 kallikrein-related peptidase 6 -0.00514284
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -0.00514094
TIMP2 TIMP metallopeptidase inhibitor 2 -0.00513077
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.00512563
FOS FBJ murine osteosarcoma viral oncogene homolog -0.00511339
SASH1 SAM and SH3 domain containing 1 -0.00507691
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -0.00507139
CRYAB crystallin, alpha B -0.00506187
EIF6 eukaryotic translation initiation factor 6 -0.00505812
DSG3 desmoglein 3 -0.00503105
PSCA prostate stem cell antigen -0.00501834
A2M alpha-2-macroglobulin -0.00501372
RGS5 regulator of G-protein signaling 5 -0.00501336
TCTA T-cell leukemia translocation altered -0.00498925
RAB13 RAB13, member RAS oncogene family -0.00498905
MMD monocyte to macrophage differentiation-associated -0.00498491
GPM6B glycoprotein M6B -0.00498241
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 -0.0049785
MT1H metallothionein 1H -0.00495722
MMP19 matrix metallopeptidase 19 -0.00495411
MXI1 MAX interactor 1, dimerization protein -0.00495213
PCOLCE procollagen C-endopeptidase enhancer -0.00494947
SPON2 spondin 2, extracellular matrix protein -0.00493146
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 -0.00492944
L1CAM L1 cell adhesion molecule -0.00492842
BHLHE41 basic helix-loop-helix family, member e41 -0.00490425
EPS8L1 EPS8-like 1 -0.0048849
MECOM MDS1 and EVI1 complex locus -0.00488405
KRT6B keratin 6B, type II -0.00488379
MFAP5 microfibrillar associated protein 5 -0.00488094
RGL1 ral guanine nucleotide dissociation stimulator-like 1 -0.00487771
QPRT quinolinate phosphoribosyltransferase -0.00487769
RNPS1 RNA binding protein S1, serine-rich domain -0.00487718
DAAM2 dishevelled associated activator of morphogenesis 2 -0.00486156
APRT adenine phosphoribosyltransferase -0.00485829
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -0.00484898
TYRP1 tyrosinase-related protein 1 -0.00484241
ZNF91 zinc finger protein 91 -0.00483828
WBP5 WW domain binding protein 5 -0.00482602
RNF44 ring finger protein 44 -0.00481671
CFI complement factor I -0.00480033
TSPAN12 tetraspanin 12 -0.00479793
TCTN2 tectonic family member 2 -0.00478777
CPNE1 copine I -0.00478227
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00477498
CSF1 colony stimulating factor 1 (macrophage) -0.00476017
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -0.00475403
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.00474173
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.00473768
H1-2 H1.2 linker histone, cluster member -0.00472959
KRT15 keratin 15, type I -0.00472799
FJX1 four jointed box 1 (Drosophila) -0.00472331
DUSP1 dual specificity phosphatase 1 -0.00471401
JMJD6 jumonji domain containing 6 -0.00470108
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 -0.00470006
SDC3 syndecan 3 -0.00467902
ADRA2A adrenoceptor alpha 2A -0.00467494
SPRR3 small proline-rich protein 3 -0.00467033
STX4 syntaxin 4 -0.00465032
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) -0.00464687
USP9X ubiquitin specific peptidase 9, X-linked -0.00461795
PPP2R2B protein phosphatase 2, regulatory subunit B, beta -0.0046099
POSTN periostin, osteoblast specific factor -0.00460213
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 -0.00459918
PLIN1 perilipin 1 -0.00459022
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) -0.0045859
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 -0.00457748
TTR transthyretin -0.00457724
BRD4 bromodomain containing 4 -0.00457003
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 -0.00456784
RHCG Rh family, C glycoprotein -0.00455515
KRT6A keratin 6A, type II -0.00455354