RXRG Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description retinoid X receptor, gamma|This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010] (NCBI Entrez Gene Database, 6258)
External Link http://www.ncbi.nlm.nih.gov/gene/6258
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Genes

41 interacting proteins for RXRG from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AJUBA ajuba LIM protein
AKT1 v-akt murine thymoma viral oncogene homolog 1
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CHGB chromogranin B
CREBBP CREB binding protein
CUL1 cullin 1
DCK deoxycytidine kinase
HOXD4 homeobox D4
ITGB3BP integrin beta 3 binding protein (beta3-endonexin)
LRSAM1 leucine rich repeat and sterile alpha motif containing 1
MAP4 microtubule-associated protein 4
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCOA6 nuclear receptor coactivator 6
NCOR2 nuclear receptor corepressor 2
NR0B2 nuclear receptor subfamily 0, group B, member 2
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR4A1 nuclear receptor subfamily 4, group A, member 1
PNO1 partner of NOB1 homolog (S. cerevisiae)
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PRKCA protein kinase C, alpha
PRKCG protein kinase C, gamma
RARA retinoic acid receptor, alpha
RARB retinoic acid receptor, beta
RARG retinoic acid receptor, gamma
RPAP2 RNA polymerase II associated protein 2
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SRF serum response factor (c-fos serum response element-binding transcription factor)
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
THRA thyroid hormone receptor, alpha
THRB thyroid hormone receptor, beta
UBC ubiquitin C
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
ZNF148 zinc finger protein 148