Rab geranylgeranyltransferase activity Gene Set

Dataset GO Molecular Function Annotations 2023
Category structural or functional annotations
Type biological process
Description Catalysis of the reaction: 2 geranylgeranyl diphosphate + protein-cysteine = 2 S-geranylgeranyl-protein + 2 diphosphate. This reaction is the formation of two thioether linkages between the C-1 atom of the geranylgeranyl groups and two cysteine residues within the terminal sequence motifs XXCC, XCXC or CCXX. Known substrates include Ras-related GTPases of a single family and the Rab family. (Gene Ontology, GO_0004663)
External Link http://amigo.geneontology.org/amigo/term/GO:0004663
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Genes

3 genes performing the Rab geranylgeranyltransferase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

Symbol Name
CHM choroideremia (Rab escort protein 1)
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RABGGTB Rab geranylgeranyltransferase, beta subunit