| Dataset | GO Molecular Function Annotations 2025 |
| Category | structural or functional annotations |
| Type | molecular function |
| Description | Catalysis of the reaction: 2 geranylgeranyl diphosphate + protein-cysteine = 2 S-geranylgeranyl-protein + 2 diphosphate. This reaction is the formation of two thioether linkages between the C-1 atom of the geranylgeranyl groups and two cysteine residues within the terminal sequence motifs XXCC, XCXC or CCXX. Known substrates include Ras-related GTPases of a single family and the Rab family. (Gene Ontology, GO_0004663) |
| External Link | http://amigo.geneontology.org/amigo/term/GO:0004663 |
| Similar Terms | |
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4 genes performing the Rab geranylgeranyltransferase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.
