| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/107751 |
| Similar Terms | |
| Downloads & Tools |
200 proteins with high or low expression in Racecadotril relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PREX1 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 | 1.21 |
| GGT1 | gamma-glutamyltransferase 1 | 1.01 |
| MYL3 | myosin, light chain 3, alkali; ventricular, skeletal, slow | 0.93 |
| IFI35 | interferon-induced protein 35 | 0.84 |
| CALU | calumenin | 0.62 |
| SGSH | N-sulfoglucosamine sulfohydrolase | 0.6 |
| NIPSNAP3A | nipsnap homolog 3A (C. elegans) | 0.5 |
| MTSS2 | MTSS I-BAR domain containing 2 | 0.49 |
| ODF2L | outer dense fiber of sperm tails 2-like | 0.47 |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha | 0.46 |
| GRID1 | glutamate receptor, ionotropic, delta 1 | 0.45 |
| YBX3 | Y box binding protein 3 | 0.45 |
| RUFY3 | RUN and FYVE domain containing 3 | 0.44 |
| SERF2 | small EDRK-rich factor 2 | 0.44 |
| SCLT1 | sodium channel and clathrin linker 1 | 0.42 |
| ZNF566 | zinc finger protein 566 | 0.38 |
| ANKRD20A4 | ankyrin repeat domain 20 family, member A4 | 0.38 |
| CST6 | cystatin E/M | 0.37 |
| SYAP1 | synapse associated protein 1 | 0.36 |
| H3C1 | H3 clustered histone 1 | 0.36 |
| ALG8 | ALG8, alpha-1,3-glucosyltransferase | 0.35 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.35 |
| PROSER3 | proline and serine rich 3 | 0.34 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) | 0.34 |
| ZBTB25 | zinc finger and BTB domain containing 25 | 0.34 |
| PLEK | pleckstrin | 0.34 |
| ODC1 | ornithine decarboxylase 1 | 0.33 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 | 0.33 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.32 |
| ZNF791 | zinc finger protein 791 | 0.31 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.31 |
| SP2 | Sp2 transcription factor | 0.31 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.31 |
| HPS1 | Hermansky-Pudlak syndrome 1 | 0.3 |
| PRR3 | proline rich 3 | 0.3 |
| ABHD18 | abhydrolase domain containing 18 | 0.3 |
| ZNF189 | zinc finger protein 189 | 0.3 |
| RNF145 | ring finger protein 145 | 0.29 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | 0.29 |
| TRAF3 | TNF receptor-associated factor 3 | 0.29 |
| HOXA10 | homeobox A10 | 0.29 |
| CCN3 | cellular communication network factor 3 | 0.29 |
| NEDD8 | neural precursor cell expressed, developmentally down-regulated 8 | 0.29 |
| KRTCAP3 | keratinocyte associated protein 3 | 0.29 |
| DES | desmin | 0.29 |
| HSPA1L | heat shock 70kDa protein 1-like | 0.29 |
| ENO1 | enolase 1, (alpha) | 0.28 |
| METRN | meteorin, glial cell differentiation regulator | 0.28 |
| MCM9 | minichromosome maintenance complex component 9 | 0.28 |
| KLHL15 | kelch-like family member 15 | 0.28 |
| KANK3 | KN motif and ankyrin repeat domains 3 | 0.28 |
| PEX5 | peroxisomal biogenesis factor 5 | 0.28 |
| ZNF225 | zinc finger protein 225 | 0.27 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.27 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.27 |
| ZCCHC10 | zinc finger, CCHC domain containing 10 | 0.27 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 | 0.27 |
| FRS2 | fibroblast growth factor receptor substrate 2 | 0.26 |
| AXL | AXL receptor tyrosine kinase | 0.26 |
| BAIAP2 | BAI1-associated protein 2 | 0.26 |
| PUM1 | pumilio RNA-binding family member 1 | 0.26 |
| TMEM192 | transmembrane protein 192 | 0.26 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 | 0.26 |
| GAS8 | growth arrest-specific 8 | 0.26 |
| BORA | bora, aurora kinase A activator | 0.26 |
| IFT43 | intraflagellar transport 43 | 0.25 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) | 0.25 |
| WDR34 | WD repeat domain 34 | 0.25 |
| ATP13A2 | ATPase type 13A2 | 0.25 |
| FAM241B | family with sequence similarity 241 member B | 0.25 |
| ITGA6 | integrin, alpha 6 | 0.25 |
| SH3RF2 | SH3 domain containing ring finger 2 | 0.25 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | 0.24 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | 0.24 |
| FAM177A1 | family with sequence similarity 177, member A1 | 0.24 |
| ZNF561 | zinc finger protein 561 | 0.24 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.24 |
| CRCP | CGRP receptor component | 0.24 |
| NUDT14 | nudix (nucleoside diphosphate linked moiety X)-type motif 14 | 0.24 |
| OIP5 | Opa interacting protein 5 | 0.23 |
| ZNF567 | zinc finger protein 567 | 0.23 |
| TBC1D30 | TBC1 domain family, member 30 | 0.23 |
| ZNF778 | zinc finger protein 778 | 0.23 |
| SETDB2 | SET domain, bifurcated 2 | 0.23 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.23 |
| ZNF100 | zinc finger protein 100 | 0.23 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.23 |
| CSNK1G3 | casein kinase 1, gamma 3 | 0.23 |
| CCNF | cyclin F | 0.23 |
| SORT1 | sortilin 1 | 0.23 |
| LSM3 | LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.23 |
| ANKRD44 | ankyrin repeat domain 44 | 0.22 |
| SNPH | syntaphilin | 0.22 |
| GTF2A2 | general transcription factor IIA, 2, 12kDa | 0.22 |
| CACNA1E | calcium channel, voltage-dependent, R type, alpha 1E subunit | 0.22 |
| SLBP | stem-loop binding protein | 0.22 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | 0.22 |
| ACTL8 | actin-like 8 | 0.22 |
| SON | SON DNA binding protein | 0.22 |
| DDX4 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 | 0.22 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CA3 | carbonic anhydrase III | -1.37 |
| ALPK3 | alpha-kinase 3 | -0.94 |
| PDP2 | pyruvate dehyrogenase phosphatase catalytic subunit 2 | -0.74 |
| GSTM4 | glutathione S-transferase mu 4 | -0.67 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.65 |
| LRRK1 | leucine-rich repeat kinase 1 | -0.61 |
| VAV1 | vav 1 guanine nucleotide exchange factor | -0.59 |
| ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | -0.58 |
| MYH8 | myosin, heavy chain 8, skeletal muscle, perinatal | -0.57 |
| FAR2 | fatty acyl CoA reductase 2 | -0.55 |
| VIM | vimentin | -0.55 |
| GKAP1 | G kinase anchoring protein 1 | -0.53 |
| BCL2L12 | BCL2-like 12 (proline rich) | -0.53 |
| GRAMD2B | GRAM domain containing 2B | -0.52 |
| TMEM189 | transmembrane protein 189 | -0.52 |
| MED29 | mediator complex subunit 29 | -0.52 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.52 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.51 |
| DUSP14 | dual specificity phosphatase 14 | -0.49 |
| CNTN1 | contactin 1 | -0.48 |
| TPM1 | tropomyosin 1 (alpha) | -0.48 |
| TNNI2 | troponin I type 2 (skeletal, fast) | -0.47 |
| ACTN3 | actinin, alpha 3 (gene/pseudogene) | -0.47 |
| UNKL | unkempt family zinc finger-like | -0.47 |
| HRH1 | histamine receptor H1 | -0.46 |
| MYH4 | myosin, heavy chain 4, skeletal muscle | -0.46 |
| INPP5J | inositol polyphosphate-5-phosphatase J | -0.45 |
| RAB40C | RAB40C, member RAS oncogene family | -0.44 |
| DBI | diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) | -0.44 |
| CYBA | cytochrome b-245, alpha polypeptide | -0.44 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.43 |
| SLC45A4 | solute carrier family 45, member 4 | -0.43 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | -0.43 |
| FAM102B | family with sequence similarity 102, member B | -0.43 |
| COL1A2 | collagen, type I, alpha 2 | -0.43 |
| TSPAN3 | tetraspanin 3 | -0.41 |
| ATF3 | activating transcription factor 3 | -0.41 |
| FBXO41 | F-box protein 41 | -0.4 |
| ZNF483 | zinc finger protein 483 | -0.4 |
| TSPAN33 | tetraspanin 33 | -0.4 |
| SEMG2 | semenogelin II | -0.4 |
| POLR2M | polymerase (RNA) II (DNA directed) polypeptide M | -0.38 |
| TIMM8A | translocase of inner mitochondrial membrane 8 homolog A (yeast) | -0.38 |
| GSTM5 | glutathione S-transferase mu 5 | -0.38 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | -0.37 |
| HLA-B | major histocompatibility complex, class I, B | -0.37 |
| ZNF594 | zinc finger protein 594 | -0.37 |
| NRP1 | neuropilin 1 | -0.36 |
| CYBRD1 | cytochrome b reductase 1 | -0.35 |
| MYH3 | myosin, heavy chain 3, skeletal muscle, embryonic | -0.35 |
| FN1 | fibronectin 1 | -0.35 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | -0.34 |
| LYRM1 | LYR motif containing 1 | -0.34 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 | -0.34 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.33 |
| FGFBP1 | fibroblast growth factor binding protein 1 | -0.33 |
| PCSK9 | proprotein convertase subtilisin/kexin type 9 | -0.33 |
| LYPD3 | LY6/PLAUR domain containing 3 | -0.33 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | -0.33 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult | -0.33 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) | -0.33 |
| DEF8 | differentially expressed in FDCP 8 homolog (mouse) | -0.33 |
| HMGXB4 | HMG box domain containing 4 | -0.32 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.32 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.32 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 | -0.32 |
| ERG28 | ergosterol biosynthesis 28 homolog | -0.32 |
| TPM4 | tropomyosin 4 | -0.32 |
| C12ORF57 | chromosome 12 open reading frame 57 | -0.31 |
| RNF26 | ring finger protein 26 | -0.31 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 | -0.31 |
| TAF11 | TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa | -0.31 |
| PCMTD1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 | -0.31 |
| ECM1 | extracellular matrix protein 1 | -0.31 |
| C15ORF61 | chromosome 15 open reading frame 61 | -0.31 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.3 |
| BCLAF3 | BCLAF1 and THRAP3 family member 3 | -0.3 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 | -0.3 |
| FTL | ferritin, light polypeptide | -0.3 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.3 |
| GJC1 | gap junction protein, gamma 1, 45kDa | -0.3 |
| SLX4 | SLX4 structure-specific endonuclease subunit | -0.3 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.3 |
| RNF181 | ring finger protein 181 | -0.29 |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) | -0.29 |
| C1ORF50 | chromosome 1 open reading frame 50 | -0.29 |
| CLSTN3 | calsyntenin 3 | -0.29 |
| CENPT | centromere protein T | -0.29 |
| C4BPA | complement component 4 binding protein, alpha | -0.28 |
| SGMS1 | sphingomyelin synthase 1 | -0.28 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | -0.28 |
| CCDC158 | coiled-coil domain containing 158 | -0.28 |
| MYH6 | myosin, heavy chain 6, cardiac muscle, alpha | -0.28 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.28 |
| BRD7 | bromodomain containing 7 | -0.28 |
| ZNF195 | zinc finger protein 195 | -0.28 |
| MDM1 | Mdm1 nuclear protein homolog (mouse) | -0.28 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.28 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | -0.28 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.28 |
