Radiculopathy Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
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Genes

236 genes co-occuring with the disease Radiculopathy in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
LAPTM4A lysosomal protein transmembrane 4 alpha 2.755
TAC1 tachykinin, precursor 1 2.522
BMP2 bone morphogenetic protein 2 2.419
CRP C-reactive protein, pentraxin-related 2.319
ACAN aggrecan 2.245
NGF nerve growth factor (beta polypeptide) 2.234
IL1B interleukin 1, beta 2.224
SCN9A sodium channel, voltage gated, type IX alpha subunit 2.208
IL6 interleukin 6 2.19
TRPV1 transient receptor potential cation channel, subfamily V, member 1 2.183
TNF tumor necrosis factor 2.163
CKB creatine kinase, brain 2.001
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 2.001
CKMT1B creatine kinase, mitochondrial 1B 2.0
CKM creatine kinase, muscle 1.996
NFASC neurofascin 1.954
SCN10A sodium channel, voltage gated, type X alpha subunit 1.939
CNTN1 contactin 1 1.848
DPYSL5 dihydropyrimidinase-like 5 1.831
TRPA1 transient receptor potential cation channel, subfamily A, member 1 1.811
IL1A interleukin 1, alpha 1.8
BDNF brain-derived neurotrophic factor 1.79
ALB albumin 1.773
AMPH amphiphysin 1.754
KNG1 kininogen 1 1.748
MAG myelin associated glycoprotein 1.744
ASIC3 acid sensing (proton gated) ion channel 3 1.741
CD4 CD4 molecule 1.732
MMP3 matrix metallopeptidase 3 1.729
ARTN artemin 1.723
IL10 interleukin 10 1.699
SCN11A sodium channel, voltage gated, type XI alpha subunit 1.689
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.686
OPRM1 opioid receptor, mu 1 1.675
VASN vasorin 1.67
CXCL8 chemokine (C-X-C motif) ligand 8 1.667
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 1.665
TGFB1 transforming growth factor, beta 1 1.656
MOG myelin oligodendrocyte glycoprotein 1.643
MMP13 matrix metallopeptidase 13 1.642
GDF6 growth differentiation factor 6 1.633
NEFL neurofilament, light polypeptide 1.632
LIPN lipase, family member N 1.625
BIN1 bridging integrator 1 1.624
ACE angiotensin I converting enzyme 1.622
IL4 interleukin 4 1.618
CCL2 chemokine (C-C motif) ligand 2 1.613
IL17A interleukin 17A 1.609
CNTNAP1 contactin associated protein 1 1.608
GFAP glial fibrillary acidic protein 1.598
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 1.592
LGI1 leucine-rich, glioma inactivated 1 1.576
CD68 CD68 molecule 1.571
INS insulin 1.561
GDF5 growth differentiation factor 5 1.554
TTR transthyretin 1.54
PRTN3 proteinase 3 1.531
NF1 neurofibromin 1 1.53
CNTNAP2 contactin associated protein-like 2 1.53
SCN3A sodium channel, voltage gated, type III alpha subunit 1.53
ATF3 activating transcription factor 3 1.519
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 1.506
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 1.496
BMP7 bone morphogenetic protein 7 1.493
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 1.479
IFNG interferon, gamma 1.479
NEFH neurofilament, heavy polypeptide 1.466
AIF1 allograft inflammatory factor 1 1.461
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.454
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 1.454
COL6A1 collagen, type VI, alpha 1 1.453
MBP myelin basic protein 1.453
CD8A CD8a molecule 1.446
ENO2 enolase 2 (gamma, neuronal) 1.439
TBPL1 TBP-like 1 1.429
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit 1.419
IGF1 insulin-like growth factor 1 (somatomedin C) 1.411
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.399
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.398
MYOM2 myomesin 2 1.396
PTH parathyroid hormone 1.393
JUN jun proto-oncogene 1.389
SYP synaptophysin 1.386
TRPM8 transient receptor potential cation channel, subfamily M, member 8 1.385
TSPO translocator protein (18kDa) 1.382
UFL1 UFM1-specific ligase 1 1.366
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.366
MUSK muscle, skeletal, receptor tyrosine kinase 1.362
F2 coagulation factor II (thrombin) 1.36
KLHL11 kelch-like family member 11 1.36
GDNF glial cell derived neurotrophic factor 1.356
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 1.355
BGLAP bone gamma-carboxyglutamate (gla) protein 1.351
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 1.35
TLR4 toll-like receptor 4 1.348
POMC proopiomelanocortin 1.343
CCL3 chemokine (C-C motif) ligand 3 1.342
NPY neuropeptide Y 1.341
GFRA3 GDNF family receptor alpha 3 1.34
SCN8A sodium channel, voltage gated, type VIII alpha subunit 1.339
CCL5 chemokine (C-C motif) ligand 5 1.338
PNMA2 paraneoplastic Ma antigen 2 1.321
PDYN prodynorphin 1.319
FGF2 fibroblast growth factor 2 (basic) 1.316
F3 coagulation factor III (thromboplastin, tissue factor) 1.31
SOX9 SRY (sex determining region Y)-box 9 1.299
PMP22 peripheral myelin protein 22 1.29
IL2 interleukin 2 1.277
TRPV4 transient receptor potential cation channel, subfamily V, member 4 1.272
SEPTIN9 septin 9 1.271
HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 1.267
FOS FBJ murine osteosarcoma viral oncogene homolog 1.266
SOD1 superoxide dismutase 1, soluble 1.265
ACE2 angiotensin I converting enzyme 2 1.259
ELN elastin 1.251
CD99 CD99 molecule 1.251
MMP9 matrix metallopeptidase 9 1.248
TIMP1 TIMP metallopeptidase inhibitor 1 1.244
C9ORF72 chromosome 9 open reading frame 72 1.241
IL1RN interleukin 1 receptor antagonist 1.24
TARDBP TAR DNA binding protein 1.239
ZIC4 Zic family member 4 1.225
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.225
MMP1 matrix metallopeptidase 1 1.221
FUS FUS RNA binding protein 1.219
GLDN gliomedin 1.219
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) 1.219
ANK1 ankyrin 1, erythrocytic 1.213
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 1.211
DPP10 dipeptidyl-peptidase 10 (non-functional) 1.209
COL2A1 collagen, type II, alpha 1 1.206
COL9A3 collagen, type IX, alpha 3 1.204
GSDMC gasdermin C 1.203
TGFB3 transforming growth factor, beta 3 1.197
PXDNL peroxidasin-like 1.194
PXDN peroxidasin 1.193
GRM1 glutamate receptor, metabotropic 1 1.192
CD34 CD34 molecule 1.189
OR5H15 olfactory receptor, family 5, subfamily H, member 15 1.188
SPIC Spi-C transcription factor (Spi-1/PU.1 related) 1.187
COL9A2 collagen, type IX, alpha 2 1.186
SCN4A sodium channel, voltage gated, type IV alpha subunit 1.177
B2M beta-2-microglobulin 1.176
PTPRC protein tyrosine phosphatase, receptor type, C 1.172
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.171
BMP4 bone morphogenetic protein 4 1.169
COL11A2 collagen, type XI, alpha 2 1.166
SCN1A sodium channel, voltage gated, type I alpha subunit 1.161
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.159
FGF18 fibroblast growth factor 18 1.158
CALCA calcitonin-related polypeptide alpha 1.155
DPP6 dipeptidyl-peptidase 6 1.153
FN1 fibronectin 1 1.144
TLR2 toll-like receptor 2 1.142
BGN biglycan 1.142
LEP leptin 1.141
LUZP4 leucine zipper protein 4 1.14
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit 1.137
FGF9 fibroblast growth factor 9 1.135
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 1.134
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 1.134
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.133
IL13 interleukin 13 1.126
FGF16 fibroblast growth factor 16 1.122
SMN1 survival of motor neuron 1, telomeric 1.12
WIPF3 WAS/WASL interacting protein family, member 3 1.116
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.115
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.115
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.114
FGF4 fibroblast growth factor 4 1.114
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.113
GAP43 growth associated protein 43 1.112
FGF22 fibroblast growth factor 22 1.109
FGF3 fibroblast growth factor 3 1.109
FGF6 fibroblast growth factor 6 1.107
GDF2 growth differentiation factor 2 1.105
FGF20 fibroblast growth factor 20 1.104
FGF17 fibroblast growth factor 17 1.102
FGF5 fibroblast growth factor 5 1.099
SOST sclerostin 1.098
CCR2 chemokine (C-C motif) receptor 2 1.094
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.091
CX3CR1 chemokine (C-X3-C motif) receptor 1 1.087
FGF8 fibroblast growth factor 8 (androgen-induced) 1.084
RUNX2 runt-related transcription factor 2 1.084
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.083
FGF10 fibroblast growth factor 10 1.079
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.078
CCL4 chemokine (C-C motif) ligand 4 1.077
SST somatostatin 1.077
IL18 interleukin 18 1.074
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.073
OR2G3 olfactory receptor, family 2, subfamily G, member 3 1.07
FGF7 fibroblast growth factor 7 1.07
CCDC91 coiled-coil domain containing 91 1.069
IHH indian hedgehog 1.069
PENK proenkephalin 1.067
OSTF1 osteoclast stimulating factor 1 1.065
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.063
RNMT RNA (guanine-7-) methyltransferase 1.062
PRX periaxin 1.062
CXCL10 chemokine (C-X-C motif) ligand 10 1.061
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.061
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.06
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.055
IFNA1 interferon, alpha 1 1.051
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.043
CD99L2 CD99 molecule-like 2 1.039
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 1.039
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 1.034
IFNB1 interferon, beta 1, fibroblast 1.034
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.033
RSPO2 R-spondin 2 1.032
SMN2 survival of motor neuron 2, centromeric 1.031
ACTB actin, beta 1.03
PRKCG protein kinase C, gamma 1.03
TACR1 tachykinin receptor 1 1.029
PIEZO2 piezo-type mechanosensitive ion channel component 2 1.027
SPP1 secreted phosphoprotein 1 1.027
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.021
GRIA1 glutamate receptor, ionotropic, AMPA 1 1.021
GJB1 gap junction protein, beta 1, 32kDa 1.021
PTHLH parathyroid hormone-like hormone 1.02
COMT catechol-O-methyltransferase 1.02
LRP5 low density lipoprotein receptor-related protein 5 1.019
PAX1 paired box 1 1.019
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 1.017
NCAM1 neural cell adhesion molecule 1 1.016
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5 1.015
FLYWCH1 FLYWCH-type zinc finger 1 1.012
GFRA1 GDNF family receptor alpha 1 1.01
CD19 CD19 molecule 1.01
SOX1 SRY (sex determining region Y)-box 1 1.009
SDC1 syndecan 1 1.002
CD1E CD1e molecule 1.0
MAPT microtubule-associated protein tau 1.0