| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Radotinib perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Radotinib_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.146858 |
| MAP1B | microtubule-associated protein 1B | 0.093876 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0929944 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0855086 |
| IGF2 | insulin-like growth factor 2 | 0.0773216 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0765813 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0669094 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0614237 |
| GPC5 | glypican 5 | 0.0543676 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0541061 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.053929 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0526319 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0506097 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0504355 |
| PKM | pyruvate kinase, muscle | 0.0487933 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0479183 |
| FMN1 | formin 1 | 0.0474764 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0433005 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0429123 |
| APP | amyloid beta (A4) precursor protein | 0.0416769 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0389952 |
| GOLGA4 | golgin A4 | 0.0383581 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0374217 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0364149 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0360391 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0356493 |
| FHIT | fragile histidine triad | 0.0352211 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0349967 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0348642 |
| DNMBP | dynamin binding protein | 0.0343651 |
| DPH6 | diphthamine biosynthesis 6 | 0.0342521 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0334896 |
| MEF2A | myocyte enhancer factor 2A | 0.0334042 |
| CRH | corticotropin releasing hormone | 0.0333771 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0319708 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0313069 |
| MX1 | MX dynamin-like GTPase 1 | 0.0312691 |
| MMP2 | matrix metallopeptidase 2 | 0.0311812 |
| TCF12 | transcription factor 12 | 0.0311222 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0308703 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0306943 |
| TPR | translocated promoter region, nuclear basket protein | 0.0304937 |
| USP34 | ubiquitin specific peptidase 34 | 0.0302392 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0302348 |
| B2M | beta-2-microglobulin | 0.0301479 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0301058 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0300234 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0300065 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0298422 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0297298 |
| AMOTL1 | angiomotin like 1 | 0.0297093 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0288023 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.0287223 |
| RBM20 | RNA binding motif protein 20 | 0.028131 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0278957 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0274915 |
| IFI44L | interferon-induced protein 44-like | 0.0274019 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0273683 |
| SET | SET nuclear proto-oncogene | 0.0270874 |
| CDK19 | cyclin-dependent kinase 19 | 0.0270563 |
| ANO6 | anoctamin 6 | 0.0267303 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.0264976 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0264201 |
| AOPEP | aminopeptidase O (putative) | 0.0263248 |
| MATR3 | matrin 3 | 0.0262407 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | 0.0261986 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0260262 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0256801 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0255611 |
| RPL35A | ribosomal protein L35a | 0.0254385 |
| CENPF | centromere protein F, 350/400kDa | 0.0252597 |
| INVS | inversin | 0.025256 |
| PHIP | pleckstrin homology domain interacting protein | 0.0247694 |
| MYO6 | myosin VI | 0.0243774 |
| MYO9B | myosin IXB | 0.0243773 |
| RPS12 | ribosomal protein S12 | 0.0242557 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0241035 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0238194 |
| RPS3 | ribosomal protein S3 | 0.0237795 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0236661 |
| RPS6 | ribosomal protein S6 | 0.0235625 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0235124 |
| NF1 | neurofibromin 1 | 0.023309 |
| TRPA1 | transient receptor potential cation channel, subfamily A, member 1 | 0.0232602 |
| ANGPT1 | angiopoietin 1 | 0.0232434 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0229576 |
| PTMA | prothymosin, alpha | 0.0229487 |
| H3-3B | H3.3 histone B | 0.022816 |
| TXNRD1 | thioredoxin reductase 1 | 0.0227622 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0226638 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.022626 |
| SHPRH | SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase | 0.0225614 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0225409 |
| SRPK2 | SRSF protein kinase 2 | 0.0225277 |
| ZNF292 | zinc finger protein 292 | 0.0223619 |
| PCNX1 | pecanex 1 | 0.0223102 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0222935 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0222211 |
| SPOP | speckle-type POZ protein | 0.0221574 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0220724 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | -0.187098 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0974475 |
| TLE4 | transducin-like enhancer of split 4 | -0.0920776 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0852994 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0822607 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0776661 |
| PRKCA | protein kinase C, alpha | -0.069748 |
| VMP1 | vacuole membrane protein 1 | -0.0607623 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0559962 |
| TPM1 | tropomyosin 1 (alpha) | -0.0497534 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0478371 |
| AEBP2 | AE binding protein 2 | -0.0458675 |
| RNF150 | ring finger protein 150 | -0.0452329 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0450219 |
| MYO1E | myosin IE | -0.0426001 |
| TRIB2 | tribbles pseudokinase 2 | -0.0419964 |
| INTS6 | integrator complex subunit 6 | -0.0408177 |
| PCDH9 | protocadherin 9 | -0.0406256 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0390396 |
| IGF1R | insulin-like growth factor 1 receptor | -0.039024 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0378201 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0372895 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0372224 |
| ACTG1 | actin gamma 1 | -0.0360491 |
| GOLGB1 | golgin B1 | -0.0354263 |
| MCL1 | myeloid cell leukemia 1 | -0.0347209 |
| FERMT2 | fermitin family member 2 | -0.0342224 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0337275 |
| STK38L | serine/threonine kinase 38 like | -0.0337224 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0331899 |
| RGS4 | regulator of G-protein signaling 4 | -0.0328949 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.03288 |
| FAM107B | family with sequence similarity 107, member B | -0.0327543 |
| CTBP2 | C-terminal binding protein 2 | -0.0325642 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0322357 |
| DTNA | dystrobrevin, alpha | -0.0312508 |
| ACTN1 | actinin, alpha 1 | -0.0306492 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0303399 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0303312 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0302814 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0301982 |
| FRMD4A | FERM domain containing 4A | -0.0294659 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0282838 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0279417 |
| DIAPH2 | diaphanous-related formin 2 | -0.0278159 |
| ANK2 | ankyrin 2, neuronal | -0.0277002 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0274411 |
| LSAMP | limbic system-associated membrane protein | -0.0274289 |
| RPL23 | ribosomal protein L23 | -0.0274106 |
| GSE1 | Gse1 coiled-coil protein | -0.0273753 |
| LPIN1 | lipin 1 | -0.0269258 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0268523 |
| PRKCE | protein kinase C, epsilon | -0.0266573 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0266454 |
| GLCCI1 | glucocorticoid induced 1 | -0.0263048 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0262 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0257994 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.0257737 |
| KIAA1217 | KIAA1217 | -0.0252704 |
| PCDH7 | protocadherin 7 | -0.0249515 |
| SCG2 | secretogranin II | -0.0248022 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0247646 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0245941 |
| ZNF804A | zinc finger protein 804A | -0.0245707 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0240919 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0240564 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0240525 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0239144 |
| DIPK2A | divergent protein kinase domain 2A | -0.023666 |
| MED13L | mediator complex subunit 13-like | -0.0236466 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0235871 |
| LMNA | lamin A/C | -0.0235483 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0234211 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0232545 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0232336 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0232216 |
| CHD6 | chromodomain helicase DNA binding protein 6 | -0.0231934 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0230292 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | -0.0227552 |
| AHR | aryl hydrocarbon receptor | -0.022641 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0224605 |
| IRS1 | insulin receptor substrate 1 | -0.0223262 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0221197 |
| USP15 | ubiquitin specific peptidase 15 | -0.0220052 |
| RPL9 | ribosomal protein L9 | -0.0218673 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0217988 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0217091 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0216034 |
| DST | dystonin | -0.0215243 |
| NREP | neuronal regeneration related protein | -0.0214459 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0213379 |
| DACH2 | dachshund family transcription factor 2 | -0.0211105 |
| RNF145 | ring finger protein 145 | -0.0209958 |
| MED13 | mediator complex subunit 13 | -0.0209784 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0208934 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0208875 |
| PELO | pelota homolog (Drosophila) | -0.0208575 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0208233 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0207998 |
| EFNA5 | ephrin-A5 | -0.0207733 |
