| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Radotinib perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Radotinib_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.183027 |
| MYO1E | myosin IE | 0.0764745 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0701864 |
| EGR1 | early growth response 1 | 0.0698036 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0671647 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0666499 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.063566 |
| TMC5 | transmembrane channel-like 5 | 0.0574275 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0553518 |
| VMP1 | vacuole membrane protein 1 | 0.052551 |
| EZR | ezrin | 0.0477763 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.044044 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0429403 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0416999 |
| DIAPH1 | diaphanous-related formin 1 | 0.0407782 |
| ERBIN | erbb2 interacting protein | 0.0366933 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0364511 |
| TJP1 | tight junction protein 1 | 0.0344546 |
| VEGFA | vascular endothelial growth factor A | 0.0336699 |
| CCNL1 | cyclin L1 | 0.0323528 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0322241 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.032111 |
| PKM | pyruvate kinase, muscle | 0.0320891 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0320851 |
| SEPTIN9 | septin 9 | 0.0319304 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0317418 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0304703 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0303559 |
| ITGA6 | integrin, alpha 6 | 0.0302856 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0300935 |
| POTEF | POTE ankyrin domain family, member F | 0.029803 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.029087 |
| BCL2L1 | BCL2-like 1 | 0.028562 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.0284167 |
| FHL2 | four and a half LIM domains 2 | 0.0281661 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0279482 |
| MCL1 | myeloid cell leukemia 1 | 0.027591 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0270957 |
| SLK | STE20-like kinase | 0.0264427 |
| DUSP10 | dual specificity phosphatase 10 | 0.0251593 |
| MLPH | melanophilin | 0.0246393 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0245298 |
| CLDN4 | claudin 4 | 0.0240989 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0239253 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0238926 |
| FOSL2 | FOS-like antigen 2 | 0.0234762 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0230904 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0229184 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0227791 |
| YBX3 | Y box binding protein 3 | 0.0223765 |
| STK24 | serine/threonine kinase 24 | 0.0219996 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0219666 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0213504 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.0212364 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0211503 |
| BRD2 | bromodomain containing 2 | 0.0210344 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0210102 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.020794 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0204343 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0203264 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0201522 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0200454 |
| CDHR2 | cadherin-related family member 2 | 0.0197077 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0196985 |
| KYNU | kynureninase | 0.0195164 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0192941 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.019274 |
| YAP1 | Yes-associated protein 1 | 0.0191221 |
| ANXA2 | annexin A2 | 0.0189989 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0189528 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.018612 |
| OCLN | occludin | 0.0185063 |
| CRY1 | cryptochrome circadian clock 1 | 0.0184302 |
| OXSR1 | oxidative stress responsive 1 | 0.0184027 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | 0.0183739 |
| BRD4 | bromodomain containing 4 | 0.0182758 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0181183 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0180238 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0179926 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0179531 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.01795 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0179485 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0176872 |
| ANXA11 | annexin A11 | 0.0176574 |
| PDZD8 | PDZ domain containing 8 | 0.0175402 |
| PBX4 | pre-B-cell leukemia homeobox 4 | 0.0173693 |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein | 0.0173447 |
| NBR1 | neighbor of BRCA1 gene 1 | 0.0173284 |
| ANKRD18A | ankyrin repeat domain 18A | 0.0172618 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0172401 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0171678 |
| TPM3 | tropomyosin 3 | 0.0170528 |
| DSPP | dentin sialophosphoprotein | 0.0169614 |
| PADI1 | peptidyl arginine deiminase, type I | 0.016958 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0169425 |
| PRSS22 | protease, serine, 22 | 0.0169323 |
| FAT1 | FAT atypical cadherin 1 | 0.0169285 |
| SKIL | SKI-like proto-oncogene | 0.016909 |
| AFAP1L2 | actin filament associated protein 1-like 2 | 0.0167701 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0166571 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.198598 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.179677 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.142873 |
| PTMA | prothymosin, alpha | -0.100173 |
| HLA-B | major histocompatibility complex, class I, B | -0.0981085 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0830041 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0783121 |
| RUNX1 | runt-related transcription factor 1 | -0.075823 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0695831 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0692231 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0683975 |
| RNF213 | ring finger protein 213 | -0.0640649 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.063624 |
| XAF1 | XIAP associated factor 1 | -0.0623108 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0601263 |
| H1-0 | H1.0 linker histone | -0.0587237 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0585673 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0561474 |
| LCN2 | lipocalin 2 | -0.0561437 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0537608 |
| SQSTM1 | sequestosome 1 | -0.0532056 |
| B2M | beta-2-microglobulin | -0.0513576 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0504792 |
| INTS6 | integrator complex subunit 6 | -0.0503787 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0492806 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0471605 |
| RRBP1 | ribosome binding protein 1 | -0.046801 |
| CANX | calnexin | -0.045675 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0445149 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0436827 |
| NPSR1 | neuropeptide S receptor 1 | -0.0433586 |
| NDRG1 | N-myc downstream regulated 1 | -0.0426032 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.042169 |
| IRF1 | interferon regulatory factor 1 | -0.0419987 |
| AHNAK | AHNAK nucleoprotein | -0.0419272 |
| PERP | PERP, TP53 apoptosis effector | -0.0414487 |
| RBM39 | RNA binding motif protein 39 | -0.0404755 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0401812 |
| EPCAM | epithelial cell adhesion molecule | -0.0401115 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0401054 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0397355 |
| TXNIP | thioredoxin interacting protein | -0.0396754 |
| VCL | vinculin | -0.0394627 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.039453 |
| HLA-C | major histocompatibility complex, class I, C | -0.0392181 |
| RPS24 | ribosomal protein S24 | -0.0391398 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.038792 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.038456 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0383255 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0378271 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0377577 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.037616 |
| RIGI | RNA sensor RIG-I | -0.0372531 |
| RPS6 | ribosomal protein S6 | -0.0371619 |
| RNF43 | ring finger protein 43 | -0.0369096 |
| FUS | FUS RNA binding protein | -0.0368341 |
| GNAS | GNAS complex locus | -0.0366437 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0365895 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0363508 |
| RPL35A | ribosomal protein L35a | -0.0360141 |
| EHF | ets homologous factor | -0.0358558 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0357739 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0347666 |
| RPL34 | ribosomal protein L34 | -0.0345517 |
| DIAPH3 | diaphanous-related formin 3 | -0.0341731 |
| RPLP1 | ribosomal protein, large, P1 | -0.0337813 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0335644 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0333382 |
| ATXN1 | ataxin 1 | -0.0331045 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0331007 |
| RPS8 | ribosomal protein S8 | -0.0330131 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0328099 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0327367 |
| UBC | ubiquitin C | -0.0326092 |
| PRKCA | protein kinase C, alpha | -0.0325723 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0325008 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0323812 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0320434 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0319816 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0317131 |
| ANXA4 | annexin A4 | -0.0312975 |
| PRELID2 | PRELI domain containing 2 | -0.0308601 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0306673 |
| TMSB10 | thymosin beta 10 | -0.0306561 |
| BRCA2 | breast cancer 2, early onset | -0.030579 |
| HMGB1 | high mobility group box 1 | -0.0305495 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0304493 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.0303579 |
| CALR | calreticulin | -0.0303199 |
| MKI67 | marker of proliferation Ki-67 | -0.030208 |
| S100A6 | S100 calcium binding protein A6 | -0.0296023 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0294535 |
| RPL11 | ribosomal protein L11 | -0.0293789 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0293123 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0293076 |
| SP100 | SP100 nuclear antigen | -0.0292899 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0290851 |
| SBF2 | SET binding factor 2 | -0.0289716 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0288819 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.028802 |
