| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Radotinib perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Radotinib_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PKM | pyruvate kinase, muscle | 0.202094 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.124982 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.121831 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.110869 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.105693 |
| ANXA1 | annexin A1 | 0.097286 |
| TMSB4X | thymosin beta 4, X-linked | 0.0896846 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0836797 |
| MKI67 | marker of proliferation Ki-67 | 0.0765445 |
| KIF5B | kinesin family member 5B | 0.070886 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0673265 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0672248 |
| POTEF | POTE ankyrin domain family, member F | 0.0669756 |
| RPS6 | ribosomal protein S6 | 0.064172 |
| EZR | ezrin | 0.0637985 |
| ECT2 | epithelial cell transforming 2 | 0.0637554 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0630704 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0603497 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0589603 |
| ZNF292 | zinc finger protein 292 | 0.0561587 |
| RHOA | ras homolog family member A | 0.0552551 |
| NAV2 | neuron navigator 2 | 0.0524804 |
| RPL3 | ribosomal protein L3 | 0.0519145 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.050238 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0489207 |
| RLF | rearranged L-myc fusion | 0.0464013 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.045949 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0447644 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0436093 |
| CENPF | centromere protein F, 350/400kDa | 0.0431993 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0430852 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0423044 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0416205 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0413814 |
| SIK3 | SIK family kinase 3 | 0.0405315 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0404476 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0394254 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0383388 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0380287 |
| WDR43 | WD repeat domain 43 | 0.0376435 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0368442 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0359871 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.035791 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0356648 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0350276 |
| TPX2 | TPX2, microtubule-associated | 0.0348051 |
| EVI5 | ecotropic viral integration site 5 | 0.0346849 |
| MORF4L2 | mortality factor 4 like 2 | 0.0343004 |
| QKI | QKI, KH domain containing, RNA binding | 0.0341197 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0339872 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0337978 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0332374 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0330315 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0327674 |
| PGK1 | phosphoglycerate kinase 1 | 0.0322904 |
| FAM162A | family with sequence similarity 162, member A | 0.0319552 |
| RHEB | Ras homolog enriched in brain | 0.0318654 |
| LDHA | lactate dehydrogenase A | 0.0315221 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0313184 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0310179 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0309701 |
| BMP2K | BMP2 inducible kinase | 0.030969 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0305923 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.030567 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.030346 |
| RNF145 | ring finger protein 145 | 0.0302214 |
| TFG | TRK-fused gene | 0.0301817 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0295917 |
| GOLGA4 | golgin A4 | 0.0295258 |
| NCKAP1 | NCK-associated protein 1 | 0.0289566 |
| TMEM41B | transmembrane protein 41B | 0.0288883 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0287904 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0286448 |
| RPS4X | ribosomal protein S4, X-linked | 0.0285699 |
| TPR | translocated promoter region, nuclear basket protein | 0.0281866 |
| RACK1 | receptor for activated C kinase 1 | 0.0280099 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0276362 |
| PLK2 | polo-like kinase 2 | 0.0276166 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.0275084 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0273876 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0272028 |
| MATR3 | matrin 3 | 0.026973 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0267062 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0264006 |
| USP3 | ubiquitin specific peptidase 3 | 0.0262724 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.026192 |
| LOXL3 | lysyl oxidase-like 3 | 0.0259238 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0259123 |
| HNRNPF | heterogeneous nuclear ribonucleoprotein F | 0.0257831 |
| KIF13A | kinesin family member 13A | 0.0257665 |
| NUP58 | nucleoporin 58 | 0.0256242 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0255508 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0253529 |
| PAQR3 | progestin and adipoQ receptor family member III | 0.0252754 |
| HJURP | Holliday junction recognition protein | 0.0252259 |
| RIOK3 | RIO kinase 3 | 0.0252101 |
| GOLM2 | golgi membrane protein 2 | 0.0251359 |
| IPO7 | importin 7 | 0.0250653 |
| MEF2A | myocyte enhancer factor 2A | 0.0249731 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.0249396 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.165013 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.132242 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0982212 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0893697 |
| AHNAK | AHNAK nucleoprotein | -0.0797854 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0728277 |
| EFNA5 | ephrin-A5 | -0.0727382 |
| UBC | ubiquitin C | -0.0710286 |
| EGFR | epidermal growth factor receptor | -0.0683124 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0636192 |
| RPS27A | ribosomal protein S27a | -0.0618101 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0615528 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.061424 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0562123 |
| VCL | vinculin | -0.053826 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0473561 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0460797 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0459467 |
| MYOF | myoferlin | -0.0457194 |
| HDAC9 | histone deacetylase 9 | -0.0454369 |
| INTS6 | integrator complex subunit 6 | -0.045008 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0442237 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.04386 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.043357 |
| S100A6 | S100 calcium binding protein A6 | -0.0426576 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0408317 |
| RPL9 | ribosomal protein L9 | -0.0402537 |
| TBC1D22A | TBC1 domain family, member 22A | -0.037781 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0377154 |
| RPL23 | ribosomal protein L23 | -0.0369196 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0367581 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0363687 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0348211 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0345957 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0337775 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0329121 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0320866 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0306646 |
| KLC1 | kinesin light chain 1 | -0.0300398 |
| PRELID2 | PRELI domain containing 2 | -0.0297962 |
| SMAD3 | SMAD family member 3 | -0.0288701 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0279857 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | -0.0279305 |
| TMSB10 | thymosin beta 10 | -0.0277257 |
| ASPH | aspartate beta-hydroxylase | -0.0274856 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0274104 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0266641 |
| FHIT | fragile histidine triad | -0.0258863 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.025604 |
| TJP1 | tight junction protein 1 | -0.0254486 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0252292 |
| GOSR2 | golgi SNAP receptor complex member 2 | -0.0251169 |
| FNIP1 | folliculin interacting protein 1 | -0.0248587 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0246413 |
| NFIA | nuclear factor I/A | -0.0245504 |
| RPS23 | ribosomal protein S23 | -0.024384 |
| ZNF106 | zinc finger protein 106 | -0.0240632 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0239335 |
| MLIP | muscular LMNA-interacting protein | -0.023851 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0238021 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0237354 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0237008 |
| GLI3 | GLI family zinc finger 3 | -0.0236529 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0236473 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | -0.0235049 |
| AMOTL2 | angiomotin like 2 | -0.0233254 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0232887 |
| PBRM1 | polybromo 1 | -0.0231506 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -0.023026 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.022931 |
| IRS1 | insulin receptor substrate 1 | -0.0228758 |
| RPL18 | ribosomal protein L18 | -0.0228337 |
| RPS12 | ribosomal protein S12 | -0.0227491 |
| TBCA | tubulin folding cofactor A | -0.0226357 |
| ANXA2 | annexin A2 | -0.0224462 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | -0.022053 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0217318 |
| TMEM165 | transmembrane protein 165 | -0.0217271 |
| AEBP2 | AE binding protein 2 | -0.0216815 |
| CCDC138 | coiled-coil domain containing 138 | -0.0216462 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0214917 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0213014 |
| PDE10A | phosphodiesterase 10A | -0.0212011 |
| RPLP2 | ribosomal protein, large, P2 | -0.0211263 |
| CFH | complement factor H | -0.0209677 |
| CTTN | cortactin | -0.0209291 |
| RPL12 | ribosomal protein L12 | -0.0209047 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.020828 |
| FHAD1 | forkhead-associated (FHA) phosphopeptide binding domain 1 | -0.0207647 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.020522 |
| FN1 | fibronectin 1 | -0.0204215 |
| ATXN1 | ataxin 1 | -0.0203485 |
| PPM1L | protein phosphatase, Mg2+/Mn2+ dependent, 1L | -0.0202233 |
| RPS21 | ribosomal protein S21 | -0.02017 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0201477 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0200525 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.0200342 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0198301 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0196735 |
| CTIF | CBP80/20-dependent translation initiation factor | -0.019633 |
