| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Radotinib perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Radotinib_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.152921 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.150456 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.117421 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.098353 |
| EGFR | epidermal growth factor receptor | 0.0969383 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.094526 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0914145 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.089346 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0842021 |
| CDH13 | cadherin 13 | 0.075766 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.07155 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0708323 |
| COL5A1 | collagen, type V, alpha 1 | 0.0696899 |
| FN1 | fibronectin 1 | 0.0696783 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0612233 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.058369 |
| NDRG1 | N-myc downstream regulated 1 | 0.0579217 |
| NRXN3 | neurexin 3 | 0.0574296 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.053783 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0531879 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0502347 |
| LOX | lysyl oxidase | 0.0494871 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.046712 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0456282 |
| EFNA5 | ephrin-A5 | 0.0452429 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.043368 |
| IL6 | interleukin 6 | 0.0432185 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0427825 |
| FAM13A | family with sequence similarity 13, member A | 0.0409132 |
| ASPH | aspartate beta-hydroxylase | 0.0403909 |
| LOXL2 | lysyl oxidase-like 2 | 0.0398281 |
| VEGFC | vascular endothelial growth factor C | 0.0396365 |
| ANXA5 | annexin A5 | 0.0372976 |
| MORF4L2 | mortality factor 4 like 2 | 0.0372504 |
| VIM | vimentin | 0.036612 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0353429 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0349275 |
| GOLGB1 | golgin B1 | 0.0337866 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0336435 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0334512 |
| C1D | C1D nuclear receptor corepressor | 0.0332687 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0327031 |
| USP34 | ubiquitin specific peptidase 34 | 0.0322441 |
| RND3 | Rho family GTPase 3 | 0.0318911 |
| COL7A1 | collagen, type VII, alpha 1 | 0.031738 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0310144 |
| SQSTM1 | sequestosome 1 | 0.030715 |
| COG6 | component of oligomeric golgi complex 6 | 0.030658 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0306072 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0304287 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0302262 |
| PCBP2 | poly(rC) binding protein 2 | 0.0300559 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0300368 |
| COPA | coatomer protein complex, subunit alpha | 0.0297558 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0296602 |
| ECE1 | endothelin converting enzyme 1 | 0.0295785 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0295165 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0291597 |
| MYO9A | myosin IXA | 0.0290753 |
| PRSS23 | protease, serine, 23 | 0.0284054 |
| HAPSTR1 | HUWE1 associated protein modifying stress responses | 0.0282994 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0281654 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0280833 |
| HELZ | helicase with zinc finger | 0.0277159 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0273077 |
| ARF4 | ADP-ribosylation factor 4 | 0.0268106 |
| ACTN1 | actinin, alpha 1 | 0.0267603 |
| IGF2 | insulin-like growth factor 2 | 0.0266407 |
| HMGA2 | high mobility group AT-hook 2 | 0.0266276 |
| WDR41 | WD repeat domain 41 | 0.026579 |
| ANXA1 | annexin A1 | 0.0264015 |
| FTO | fat mass and obesity associated | 0.0263586 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0262957 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0262767 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0262753 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0261772 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0260591 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0259729 |
| LDHA | lactate dehydrogenase A | 0.0255898 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0255402 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0254218 |
| DIDO1 | death inducer-obliterator 1 | 0.0253 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0246305 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0246096 |
| FRMD4A | FERM domain containing 4A | 0.0245581 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.024496 |
| FLOT1 | flotillin 1 | 0.0244691 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.024032 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0239515 |
| LAMB3 | laminin, beta 3 | 0.0238088 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0236265 |
| RASA2 | RAS p21 protein activator 2 | 0.0235972 |
| FMNL2 | formin-like 2 | 0.0235682 |
| ATP13A3 | ATPase type 13A3 | 0.0234987 |
| GOLGA3 | golgin A3 | 0.023412 |
| TUT7 | terminal uridylyl transferase 7 | 0.023142 |
| PDGFC | platelet derived growth factor C | 0.0228783 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0227166 |
| TNS3 | tensin 3 | 0.0226662 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0222916 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.140963 |
| MT2A | metallothionein 2A | -0.132265 |
| B2M | beta-2-microglobulin | -0.105819 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0864581 |
| PTMA | prothymosin, alpha | -0.0731903 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0699496 |
| HLA-B | major histocompatibility complex, class I, B | -0.0668094 |
| COL1A1 | collagen, type I, alpha 1 | -0.0599331 |
| ANLN | anillin, actin binding protein | -0.0589437 |
| H3-3B | H3.3 histone B | -0.0580355 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0547964 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0515312 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0508833 |
| RPL11 | ribosomal protein L11 | -0.0495846 |
| COL1A2 | collagen, type I, alpha 2 | -0.0495357 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0494974 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0478343 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0473734 |
| MTPN | myotrophin | -0.043131 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.041955 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0417266 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0415976 |
| MEF2A | myocyte enhancer factor 2A | -0.0412082 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0405323 |
| RPS2 | ribosomal protein S2 | -0.038954 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0379795 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0370291 |
| MT1X | metallothionein 1X | -0.0364638 |
| VCL | vinculin | -0.0363794 |
| SETD5 | SET domain containing 5 | -0.0358741 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0350963 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.0350691 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.03394 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0334569 |
| ZNF292 | zinc finger protein 292 | -0.0332644 |
| JAK1 | Janus kinase 1 | -0.032195 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0321295 |
| TMSB4X | thymosin beta 4, X-linked | -0.0321052 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0321003 |
| TXNIP | thioredoxin interacting protein | -0.0318735 |
| TPM4 | tropomyosin 4 | -0.031608 |
| GLG1 | golgi glycoprotein 1 | -0.0309857 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.030652 |
| PTN | pleiotrophin | -0.0305482 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0305402 |
| AFF4 | AF4/FMR2 family, member 4 | -0.030205 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0299364 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.029867 |
| JAG1 | jagged 1 | -0.0298207 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0298098 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0297249 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0297156 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0296136 |
| CCNI | cyclin I | -0.0294204 |
| UBC | ubiquitin C | -0.0292645 |
| JMJD1C | jumonji domain containing 1C | -0.0292491 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0291382 |
| PHF21A | PHD finger protein 21A | -0.0287916 |
| ZNF395 | zinc finger protein 395 | -0.0287514 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0287486 |
| PFN1 | profilin 1 | -0.0287172 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0286169 |
| RBM6 | RNA binding motif protein 6 | -0.0279532 |
| SMYD3 | SET and MYND domain containing 3 | -0.0279466 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | -0.0278092 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0276669 |
| FUS | FUS RNA binding protein | -0.0276152 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0272145 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0271078 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0269493 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0268794 |
| GNAS | GNAS complex locus | -0.0267918 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0267452 |
| RFWD3 | ring finger and WD repeat domain 3 | -0.026735 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0267317 |
| MKI67 | marker of proliferation Ki-67 | -0.0262849 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.0262681 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.026243 |
| RSF1 | remodeling and spacing factor 1 | -0.026202 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0261257 |
| TMEM131 | transmembrane protein 131 | -0.0260764 |
| PTGES2 | prostaglandin E synthase 2 | -0.0257552 |
| RAD51B | RAD51 paralog B | -0.0257258 |
| RPL34 | ribosomal protein L34 | -0.0253365 |
| ZNF736 | zinc finger protein 736 | -0.0249684 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0249332 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0249069 |
| RPL12 | ribosomal protein L12 | -0.0248885 |
| RPS25 | ribosomal protein S25 | -0.0247749 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0247737 |
| TNPO3 | transportin 3 | -0.0247574 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0247175 |
| RPL32 | ribosomal protein L32 | -0.0247014 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0246032 |
| TOMM7 | translocase of outer mitochondrial membrane 7 homolog (yeast) | -0.0245818 |
| DARS1 | aspartyl-tRNA synthetase 1 | -0.0244991 |
| DIAPH3 | diaphanous-related formin 3 | -0.0243515 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0242284 |
| MED13 | mediator complex subunit 13 | -0.0242218 |
| SEC24D | SEC24 family member D | -0.0240487 |
