| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Radotinib perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Radotinib_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0437892 |
| EGR1 | early growth response 1 | 0.0325079 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0315334 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0312686 |
| ZNF638 | zinc finger protein 638 | 0.0293793 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0286995 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0274011 |
| MSN | moesin | 0.0270109 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0263744 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0232695 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0226957 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0224983 |
| ANO6 | anoctamin 6 | 0.0217562 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0194956 |
| GPC5 | glypican 5 | 0.0188929 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0186189 |
| ANXA1 | annexin A1 | 0.0184738 |
| HDAC9 | histone deacetylase 9 | 0.0179587 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0178776 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0168787 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0168343 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0157719 |
| SET | SET nuclear proto-oncogene | 0.0157503 |
| CUL3 | cullin 3 | 0.015731 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0156581 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0155949 |
| SATB2 | SATB homeobox 2 | 0.0154328 |
| WWOX | WW domain containing oxidoreductase | 0.0148836 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.014573 |
| PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | 0.0145238 |
| PANX1 | pannexin 1 | 0.0143663 |
| SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 0.0143184 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.0142078 |
| FBXL4 | F-box and leucine-rich repeat protein 4 | 0.0139873 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0137744 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0136065 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0135407 |
| RUNX1 | runt-related transcription factor 1 | 0.0134702 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0134282 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0132529 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0132345 |
| LAMA5 | laminin, alpha 5 | 0.0132295 |
| RIGI | RNA sensor RIG-I | 0.0131309 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0131195 |
| TBC1D15 | TBC1 domain family, member 15 | 0.0126485 |
| COMMD1 | copper metabolism (Murr1) domain containing 1 | 0.0126211 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.0125771 |
| ATG5 | autophagy related 5 | 0.0125143 |
| CLASP1 | cytoplasmic linker associated protein 1 | 0.0124019 |
| RCOR1 | REST corepressor 1 | 0.0123815 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0123752 |
| ANGPTL4 | angiopoietin-like 4 | 0.012193 |
| SIRT1 | sirtuin 1 | 0.0120973 |
| VEGFA | vascular endothelial growth factor A | 0.0120316 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0119957 |
| NAV3 | neuron navigator 3 | 0.0118701 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0118664 |
| NEK7 | NIMA-related kinase 7 | 0.011832 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0117881 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0117343 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0117065 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.011571 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0114335 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0114301 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0113516 |
| STK38L | serine/threonine kinase 38 like | 0.0112847 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0112782 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0112778 |
| DYNC1I2 | dynein, cytoplasmic 1, intermediate chain 2 | 0.011234 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0112154 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 | 0.0112031 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.011099 |
| CLEC16A | C-type lectin domain family 16, member A | 0.0110706 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0109802 |
| DENND1A | DENN/MADD domain containing 1A | 0.0109659 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0109575 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.0109492 |
| EXT1 | exostosin glycosyltransferase 1 | 0.010943 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0109411 |
| EFL1 | elongation factor like GTPase 1 | 0.0109246 |
| LOXL2 | lysyl oxidase-like 2 | 0.0108863 |
| MRTFA | myocardin related transcription factor A | 0.0108553 |
| ZDHHC17 | zinc finger, DHHC-type containing 17 | 0.0108413 |
| EP300 | E1A binding protein p300 | 0.0107915 |
| NDUFAF2 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 | 0.0107513 |
| PRELID2 | PRELI domain containing 2 | 0.0106894 |
| IQCB1 | IQ motif containing B1 | 0.0106299 |
| FERMT2 | fermitin family member 2 | 0.0106138 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0105354 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0105181 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0104177 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.010407 |
| PPIL4 | peptidylprolyl isomerase (cyclophilin)-like 4 | 0.0104064 |
| PSEN1 | presenilin 1 | 0.010394 |
| DIAPH1 | diaphanous-related formin 1 | 0.0103822 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0103635 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0103591 |
| GTDC1 | glycosyltransferase-like domain containing 1 | 0.010356 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 | 0.0103556 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0101519 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.458286 |
| VIM | vimentin | -0.161398 |
| PTMA | prothymosin, alpha | -0.107828 |
| TMSB10 | thymosin beta 10 | -0.105144 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0682643 |
| AHNAK | AHNAK nucleoprotein | -0.0612315 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0556673 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.051713 |
| LDHA | lactate dehydrogenase A | -0.0498298 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0463241 |
| RPLP1 | ribosomal protein, large, P1 | -0.0460108 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0445813 |
| RPS8 | ribosomal protein S8 | -0.0420809 |
| ANXA2 | annexin A2 | -0.0407623 |
| TPM4 | tropomyosin 4 | -0.0398007 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0388596 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0382733 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0382359 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0370703 |
| CANX | calnexin | -0.0370053 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0358696 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0353098 |
| SLC38A2 | solute carrier family 38, member 2 | -0.03501 |
| NF1 | neurofibromin 1 | -0.0347471 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0343069 |
| RPL35A | ribosomal protein L35a | -0.0331827 |
| ACTG1 | actin gamma 1 | -0.0323483 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0322489 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0312403 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0311446 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0311289 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0309078 |
| GPC6 | glypican 6 | -0.0308887 |
| RPS6 | ribosomal protein S6 | -0.0304594 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0302207 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0301037 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0300194 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0297401 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0291174 |
| NKTR | natural killer cell triggering receptor | -0.0286732 |
| S100A10 | S100 calcium binding protein A10 | -0.0286511 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.028265 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0282335 |
| RPL32 | ribosomal protein L32 | -0.0281195 |
| TAOK1 | TAO kinase 1 | -0.0279442 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0279307 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.027821 |
| RBM39 | RNA binding motif protein 39 | -0.0277216 |
| RRBP1 | ribosome binding protein 1 | -0.0276261 |
| RPLP0 | ribosomal protein, large, P0 | -0.0273297 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0272425 |
| PGK1 | phosphoglycerate kinase 1 | -0.0271944 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0271574 |
| GOLGA4 | golgin A4 | -0.0271151 |
| SETD5 | SET domain containing 5 | -0.027045 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0270006 |
| MT2A | metallothionein 2A | -0.026374 |
| RPL12 | ribosomal protein L12 | -0.0263479 |
| MYOF | myoferlin | -0.0261179 |
| SRPK2 | SRSF protein kinase 2 | -0.0261177 |
| TMEM123 | transmembrane protein 123 | -0.0259897 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0256356 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0254667 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0252851 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0247878 |
| GNAS | GNAS complex locus | -0.0245744 |
| RDX | radixin | -0.024448 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0244041 |
| S100A9 | S100 calcium binding protein A9 | -0.0242602 |
| DSTN | destrin (actin depolymerizing factor) | -0.023991 |
| SDC4 | syndecan 4 | -0.0239632 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.023364 |
| PHF20 | PHD finger protein 20 | -0.0233425 |
| RPL19 | ribosomal protein L19 | -0.0233154 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0232151 |
| WDR45B | WD repeat domain 45B | -0.0231171 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0228571 |
| SEPTIN2 | septin 2 | -0.0228291 |
| H3-3B | H3.3 histone B | -0.0228212 |
| RPL23 | ribosomal protein L23 | -0.0227145 |
| UBB | ubiquitin B | -0.0224825 |
| FMN1 | formin 1 | -0.022378 |
| TPI1 | triosephosphate isomerase 1 | -0.0222204 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0220957 |
| SPAG9 | sperm associated antigen 9 | -0.0220871 |
| XPO1 | exportin 1 | -0.0218749 |
| ERBIN | erbb2 interacting protein | -0.0218688 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0218601 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0214519 |
| APP | amyloid beta (A4) precursor protein | -0.0214129 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0212638 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0211188 |
| RPLP2 | ribosomal protein, large, P2 | -0.0210493 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0210065 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0209824 |
| VCL | vinculin | -0.0208856 |
| YBX3 | Y box binding protein 3 | -0.0208426 |
| PYGL | phosphorylase, glycogen, liver | -0.0205636 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0203076 |
| RSF1 | remodeling and spacing factor 1 | -0.0201839 |
