| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Radotinib perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Radotinib_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.0473706 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0290727 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0289245 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0269228 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0266306 |
| NDRG1 | N-myc downstream regulated 1 | 0.0258964 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0249656 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0248631 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.024705 |
| MCL1 | myeloid cell leukemia 1 | 0.0243669 |
| POTEF | POTE ankyrin domain family, member F | 0.0236206 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0234941 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0220106 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.021079 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0207625 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0206001 |
| EGR1 | early growth response 1 | 0.0201853 |
| EMP1 | epithelial membrane protein 1 | 0.0193448 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0191183 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0184971 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0178933 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0178421 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0175607 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0174623 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0168963 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0160201 |
| STC1 | stanniocalcin 1 | 0.0158478 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0158051 |
| LMNA | lamin A/C | 0.0157606 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0152636 |
| FOSL1 | FOS-like antigen 1 | 0.0149876 |
| HMGA1 | high mobility group AT-hook 1 | 0.0143098 |
| MYADM | myeloid-associated differentiation marker | 0.0137691 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0137344 |
| BRD2 | bromodomain containing 2 | 0.0135068 |
| GRB10 | growth factor receptor-bound protein 10 | 0.013166 |
| DUSP6 | dual specificity phosphatase 6 | 0.0131066 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0130756 |
| OXR1 | oxidation resistance 1 | 0.0129879 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 0.012894 |
| FAT1 | FAT atypical cadherin 1 | 0.0128668 |
| MTSS1 | metastasis suppressor 1 | 0.012585 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0124883 |
| TGM2 | transglutaminase 2 | 0.0124716 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0124435 |
| EZR | ezrin | 0.0122423 |
| CCNL1 | cyclin L1 | 0.0121261 |
| HPS3 | Hermansky-Pudlak syndrome 3 | 0.0120494 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0118218 |
| FAM107B | family with sequence similarity 107, member B | 0.0117947 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0117119 |
| ATF3 | activating transcription factor 3 | 0.0116678 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0114415 |
| IL6 | interleukin 6 | 0.0109505 |
| GMCL1 | germ cell-less, spermatogenesis associated 1 | 0.0109174 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0107527 |
| TGFB1 | transforming growth factor, beta 1 | 0.010648 |
| CRY1 | cryptochrome circadian clock 1 | 0.0106463 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0106407 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0105367 |
| SIRT1 | sirtuin 1 | 0.0105046 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.010474 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0104313 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.010406 |
| SGMS2 | sphingomyelin synthase 2 | 0.0103335 |
| TXNIP | thioredoxin interacting protein | 0.0102439 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.00990769 |
| UBAP2 | ubiquitin associated protein 2 | 0.0099016 |
| RAI14 | retinoic acid induced 14 | 0.00985775 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.00975724 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0097279 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.00967441 |
| ITSN2 | intersectin 2 | 0.00956817 |
| RND3 | Rho family GTPase 3 | 0.00952709 |
| EPAS1 | endothelial PAS domain protein 1 | 0.00947854 |
| PER2 | period circadian clock 2 | 0.00944115 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00942086 |
| HS6ST3 | heparan sulfate 6-O-sulfotransferase 3 | 0.00935099 |
| IGF2 | insulin-like growth factor 2 | 0.00927639 |
| FBRS | fibrosin | 0.00925504 |
| PIM3 | Pim-3 proto-oncogene, serine/threonine kinase | 0.0092531 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00915314 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00913693 |
| RPL21 | ribosomal protein L21 | 0.00911617 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.00909908 |
| HLA-G | major histocompatibility complex, class I, G | 0.00902496 |
| MLF1 | myeloid leukemia factor 1 | 0.00891361 |
| CST3 | cystatin C | 0.00890261 |
| MLPH | melanophilin | 0.00884751 |
| CNOT3 | CCR4-NOT transcription complex, subunit 3 | 0.00880596 |
| CRTAC1 | cartilage acidic protein 1 | 0.0087571 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.00875103 |
| RNASEH2A | ribonuclease H2, subunit A | 0.00870622 |
| PKP2 | plakophilin 2 | 0.00867254 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.00864357 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00864134 |
| MSN | moesin | 0.00862067 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | 0.00856067 |
| ARRDC3 | arrestin domain containing 3 | 0.00855383 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.00852862 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.363586 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.211109 |
| SQSTM1 | sequestosome 1 | -0.140624 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.132777 |
| CANX | calnexin | -0.117377 |
| EXT1 | exostosin glycosyltransferase 1 | -0.109491 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.100074 |
| FN1 | fibronectin 1 | -0.0864156 |
| VCL | vinculin | -0.0862199 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0838361 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0775487 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0711018 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0691544 |
| OSMR | oncostatin M receptor | -0.0676366 |
| GLIS3 | GLIS family zinc finger 3 | -0.0654126 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0653808 |
| SYT1 | synaptotagmin I | -0.0621629 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0614937 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0591129 |
| NRG1 | neuregulin 1 | -0.0576768 |
| NRP1 | neuropilin 1 | -0.0570679 |
| TMEM156 | transmembrane protein 156 | -0.0565388 |
| DST | dystonin | -0.0556367 |
| HLA-B | major histocompatibility complex, class I, B | -0.0553022 |
| RBM39 | RNA binding motif protein 39 | -0.0545904 |
| PTMA | prothymosin, alpha | -0.0543107 |
| VIM | vimentin | -0.052964 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.052724 |
| ETV6 | ets variant 6 | -0.0522761 |
| CENPF | centromere protein F, 350/400kDa | -0.051717 |
| ITGA1 | integrin, alpha 1 | -0.0510411 |
| PRRC2C | proline-rich coiled-coil 2C | -0.050866 |
| TXNRD1 | thioredoxin reductase 1 | -0.0481837 |
| AHR | aryl hydrocarbon receptor | -0.0471774 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0464065 |
| MKI67 | marker of proliferation Ki-67 | -0.0460178 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.045615 |
| ASPH | aspartate beta-hydroxylase | -0.0454545 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0450156 |
| KLHL5 | kelch-like family member 5 | -0.0448372 |
| CAB39 | calcium binding protein 39 | -0.0443621 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0441027 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0437948 |
| SMYD3 | SET and MYND domain containing 3 | -0.0435523 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0426252 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0418268 |
| FOXP1 | forkhead box P1 | -0.0413554 |
| OGA | O-GlcNAcase | -0.0413114 |
| TMSB4X | thymosin beta 4, X-linked | -0.0413025 |
| ACTN4 | actinin, alpha 4 | -0.0399239 |
| RUNX2 | runt-related transcription factor 2 | -0.0394659 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0389564 |
| SFTPA2 | surfactant protein A2 | -0.0388764 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0386439 |
| PTK2 | protein tyrosine kinase 2 | -0.0386373 |
| FNBP1 | formin binding protein 1 | -0.0385668 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.038156 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0377228 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0374069 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0373196 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0372451 |
| CLTC | clathrin, heavy chain (Hc) | -0.0364216 |
| CD44 | CD44 molecule (Indian blood group) | -0.0363574 |
| ETNK1 | ethanolamine kinase 1 | -0.0362289 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.035967 |
| RRBP1 | ribosome binding protein 1 | -0.0358936 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0358676 |
| PELO | pelota homolog (Drosophila) | -0.0345091 |
| ETV1 | ets variant 1 | -0.0339101 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0338481 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0336636 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0334702 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0332095 |
| AHNAK | AHNAK nucleoprotein | -0.0331639 |
| RPL12 | ribosomal protein L12 | -0.0331468 |
| ARF1 | ADP-ribosylation factor 1 | -0.0330371 |
| PRELID2 | PRELI domain containing 2 | -0.0328926 |
| GNAS | GNAS complex locus | -0.0328165 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0326266 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0318378 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0317804 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0317422 |
| S100A6 | S100 calcium binding protein A6 | -0.0316482 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0313125 |
| MAP1B | microtubule-associated protein 1B | -0.0312368 |
| IL6ST | interleukin 6 signal transducer | -0.0308347 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0304446 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0300589 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0300247 |
| ENAH | enabled homolog (Drosophila) | -0.0299743 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0298382 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0297438 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0296902 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0296648 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0291684 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0291078 |
| RACK1 | receptor for activated C kinase 1 | -0.0290795 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0287637 |
| ZNF217 | zinc finger protein 217 | -0.0287132 |
| DENND5B | DENN/MADD domain containing 5B | -0.0286971 |
