| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ralimetinib dimesylate perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ralimetinib dimesylate_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0839915 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0619689 |
| VIM | vimentin | 0.0590004 |
| RPS17 | ribosomal protein S17 | 0.0537782 |
| RPL12 | ribosomal protein L12 | 0.0410762 |
| SMYD3 | SET and MYND domain containing 3 | 0.0386648 |
| RPL37A | ribosomal protein L37a | 0.0373421 |
| NAV2 | neuron navigator 2 | 0.0355976 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0354546 |
| RPS3 | ribosomal protein S3 | 0.0353595 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | 0.0337692 |
| RPL26 | ribosomal protein L26 | 0.0327919 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0300151 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0281559 |
| RPS19 | ribosomal protein S19 | 0.0274927 |
| RPL18 | ribosomal protein L18 | 0.026682 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0256193 |
| PRELID2 | PRELI domain containing 2 | 0.0251956 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0251568 |
| RPL13A | ribosomal protein L13a | 0.0248787 |
| RPL23 | ribosomal protein L23 | 0.0242302 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0242103 |
| RPS12 | ribosomal protein S12 | 0.0224603 |
| CMIP | c-Maf inducing protein | 0.0219429 |
| FLNA | filamin A, alpha | 0.0203601 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0201896 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0199904 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0193618 |
| RPS7 | ribosomal protein S7 | 0.0188928 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0180508 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | 0.0179257 |
| KLF6 | Kruppel-like factor 6 | 0.0175029 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0172871 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0171646 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0170537 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0169528 |
| RPL31 | ribosomal protein L31 | 0.0162197 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0160662 |
| PLCB4 | phospholipase C, beta 4 | 0.0160014 |
| SON | SON DNA binding protein | 0.0158237 |
| CAVIN1 | caveolae associated protein 1 | 0.0156915 |
| RPL35A | ribosomal protein L35a | 0.0156488 |
| SET | SET nuclear proto-oncogene | 0.0155356 |
| DST | dystonin | 0.015409 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0150553 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0148535 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0148135 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0146783 |
| RPLP2 | ribosomal protein, large, P2 | 0.0146763 |
| CDK6 | cyclin-dependent kinase 6 | 0.0142139 |
| RPL4 | ribosomal protein L4 | 0.0141099 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0140429 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0140274 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0139959 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.0139135 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0138274 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0136653 |
| KRT8 | keratin 8, type II | 0.0136577 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0136439 |
| PLEC | plectin | 0.013425 |
| RPL27 | ribosomal protein L27 | 0.0134125 |
| ANGPTL4 | angiopoietin-like 4 | 0.0132219 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0132139 |
| EXOC6B | exocyst complex component 6B | 0.0131618 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.013014 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0129813 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0128507 |
| STRBP | spermatid perinuclear RNA binding protein | 0.0125932 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0124653 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0123941 |
| RPS4X | ribosomal protein S4, X-linked | 0.0123238 |
| TPI1 | triosephosphate isomerase 1 | 0.0121534 |
| MINK1 | misshapen-like kinase 1 | 0.0121051 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0119295 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0116975 |
| ASPH | aspartate beta-hydroxylase | 0.0116704 |
| ACTN4 | actinin, alpha 4 | 0.0116437 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0113867 |
| RACK1 | receptor for activated C kinase 1 | 0.0112985 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0111447 |
| AHNAK | AHNAK nucleoprotein | 0.01113 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0111283 |
| TPM3 | tropomyosin 3 | 0.0109799 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0109131 |
| PHF14 | PHD finger protein 14 | 0.0108003 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0107102 |
| TSPAN15 | tetraspanin 15 | 0.0106681 |
| RPL36 | ribosomal protein L36 | 0.010447 |
| FAR1 | fatty acyl CoA reductase 1 | 0.010407 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0103797 |
| WWOX | WW domain containing oxidoreductase | 0.0103474 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0102332 |
| RPL35 | ribosomal protein L35 | 0.0101573 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0100417 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0100396 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.00988341 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.00987506 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.00967367 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.00965266 |
| UTRN | utrophin | 0.00964176 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.400132 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.22521 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.205259 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.185262 |
| NDRG1 | N-myc downstream regulated 1 | -0.182479 |
| ACTG1 | actin gamma 1 | -0.150099 |
| UBC | ubiquitin C | -0.105219 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0940601 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0859981 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.082445 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0802561 |
| STC1 | stanniocalcin 1 | -0.0762887 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0710407 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0694356 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0674499 |
| GOLGA4 | golgin A4 | -0.0655112 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.063618 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0618393 |
| RPS6 | ribosomal protein S6 | -0.0604096 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0594537 |
| SPAG9 | sperm associated antigen 9 | -0.058565 |
| POTEF | POTE ankyrin domain family, member F | -0.0579989 |
| MT1X | metallothionein 1X | -0.0576828 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0575703 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0535018 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.053065 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0528346 |
| PARD3 | par-3 family cell polarity regulator | -0.0521128 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0499537 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0493039 |
| USP3 | ubiquitin specific peptidase 3 | -0.0485037 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0484813 |
| FLNB | filamin B, beta | -0.0482775 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0480116 |
| RPS2 | ribosomal protein S2 | -0.0444953 |
| AUTS2 | autism susceptibility candidate 2 | -0.0425412 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0415772 |
| FBXO11 | F-box protein 11 | -0.0412744 |
| CA12 | carbonic anhydrase XII | -0.0411686 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0410648 |
| CANX | calnexin | -0.0406964 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0403573 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0397294 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.039665 |
| WASF2 | WAS protein family, member 2 | -0.0393846 |
| PDE10A | phosphodiesterase 10A | -0.0386002 |
| KRT81 | keratin 81, type II | -0.0385813 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0385414 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0384928 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0382693 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0373229 |
| NGLY1 | N-glycanase 1 | -0.0370283 |
| ADM | adrenomedullin | -0.036378 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0360944 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0354523 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0350016 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0344803 |
| RPS11 | ribosomal protein S11 | -0.0331972 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0327949 |
| DUSP5 | dual specificity phosphatase 5 | -0.0325288 |
| MAP1B | microtubule-associated protein 1B | -0.0325273 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0325052 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0325011 |
| S100A10 | S100 calcium binding protein A10 | -0.0323194 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.031883 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0315525 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0314636 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0314017 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0310268 |
| RPS23 | ribosomal protein S23 | -0.0307823 |
| IER3 | immediate early response 3 | -0.030742 |
| LOXL2 | lysyl oxidase-like 2 | -0.0306599 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0305089 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0299463 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.029869 |
| PKM | pyruvate kinase, muscle | -0.0297459 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0290113 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0288949 |
| CALU | calumenin | -0.02862 |
| VMP1 | vacuole membrane protein 1 | -0.0284863 |
| HELZ | helicase with zinc finger | -0.0278131 |
| OPTN | optineurin | -0.0274581 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0272076 |
| VCL | vinculin | -0.0271646 |
| ANXA2 | annexin A2 | -0.0269837 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0269171 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0268436 |
| RRBP1 | ribosome binding protein 1 | -0.0267593 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0267255 |
| WAC | WW domain containing adaptor with coiled-coil | -0.026695 |
| KYNU | kynureninase | -0.0266638 |
| FA2H | fatty acid 2-hydroxylase | -0.0265889 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0265844 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0265781 |
| RAI14 | retinoic acid induced 14 | -0.0264166 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0261457 |
| GLG1 | golgi glycoprotein 1 | -0.026078 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.025863 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0256564 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0255274 |
