| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ralimetinib dimesylate perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ralimetinib dimesylate_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MEST | mesoderm specific transcript | 0.279778 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0876999 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0444297 |
| PRELID2 | PRELI domain containing 2 | 0.0438 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0415534 |
| KAZN | kazrin, periplakin interacting protein | 0.0402441 |
| MATR3 | matrin 3 | 0.03686 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0344538 |
| PCBP2 | poly(rC) binding protein 2 | 0.0319403 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.031671 |
| ITGAV | integrin, alpha V | 0.0308765 |
| PTEN | phosphatase and tensin homolog | 0.0298705 |
| FOXP1 | forkhead box P1 | 0.0297587 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0292951 |
| RPS3 | ribosomal protein S3 | 0.0283109 |
| NFIB | nuclear factor I/B | 0.0282713 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0269628 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0267654 |
| HYOU1 | hypoxia up-regulated 1 | 0.0264098 |
| PHF14 | PHD finger protein 14 | 0.0261777 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0257064 |
| CALR | calreticulin | 0.0252596 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0250755 |
| SET | SET nuclear proto-oncogene | 0.0246728 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.024003 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0229391 |
| RPL3 | ribosomal protein L3 | 0.0223487 |
| CALD1 | caldesmon 1 | 0.0222053 |
| LMO4 | LIM domain only 4 | 0.0220514 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.021863 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0217158 |
| HOXC6 | homeobox C6 | 0.0215488 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0213894 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0213627 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0209557 |
| RPS12 | ribosomal protein S12 | 0.0207018 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0205896 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.020481 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0202907 |
| METTL15 | methyltransferase like 15 | 0.0201381 |
| ATRNL1 | attractin-like 1 | 0.0201251 |
| TXNRD1 | thioredoxin reductase 1 | 0.0200149 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0198854 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0198535 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0197591 |
| PRKD1 | protein kinase D1 | 0.0193853 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0192677 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0190108 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0189542 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0188891 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0188523 |
| ZRANB3 | zinc finger, RAN-binding domain containing 3 | 0.0188046 |
| CBX5 | chromobox homolog 5 | 0.0187996 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0187913 |
| TPI1 | triosephosphate isomerase 1 | 0.0186501 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0185975 |
| RAD51B | RAD51 paralog B | 0.018575 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.018542 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0183346 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0182599 |
| CBX3 | chromobox homolog 3 | 0.018223 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0177543 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | 0.0176194 |
| DSTN | destrin (actin depolymerizing factor) | 0.0176023 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.017556 |
| KIF11 | kinesin family member 11 | 0.0174408 |
| LMNB1 | lamin B1 | 0.0172716 |
| FANCI | Fanconi anemia, complementation group I | 0.0171541 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0171294 |
| WWOX | WW domain containing oxidoreductase | 0.0169917 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.0169308 |
| TPM3 | tropomyosin 3 | 0.0168849 |
| ITGA6 | integrin, alpha 6 | 0.0168265 |
| NIN | ninein (GSK3B interacting protein) | 0.0167216 |
| ITGB8 | integrin, beta 8 | 0.0166834 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0166774 |
| NIPSNAP2 | nipsnap homolog 2 | 0.0164766 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.0164121 |
| HELLS | helicase, lymphoid-specific | 0.0158805 |
| EGFR | epidermal growth factor receptor | 0.015798 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 0.0157567 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.0157432 |
| TRIM56 | tripartite motif containing 56 | 0.0157276 |
| CBR4 | carbonyl reductase 4 | 0.0157048 |
| RSBN1L | round spermatid basic protein 1-like | 0.0154902 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.0154318 |
| DUSP6 | dual specificity phosphatase 6 | 0.0152669 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0152387 |
| NSD1 | nuclear receptor binding SET domain protein 1 | 0.0151802 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) | 0.0151785 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0150977 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | 0.0150649 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0150499 |
| LIMA1 | LIM domain and actin binding 1 | 0.0150496 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0149914 |
| WDR41 | WD repeat domain 41 | 0.0148809 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0148236 |
| SHROOM3 | shroom family member 3 | 0.014798 |
| SMC6 | structural maintenance of chromosomes 6 | 0.0147896 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0147019 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.208795 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.163919 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0954915 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0888278 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0881692 |
| CADM2 | cell adhesion molecule 2 | -0.0822983 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0810964 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0780691 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0767173 |
| JMJD1C | jumonji domain containing 1C | -0.0736827 |
| ACTG1 | actin gamma 1 | -0.0725294 |
| FNIP1 | folliculin interacting protein 1 | -0.0715781 |
| IER3 | immediate early response 3 | -0.069819 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0671462 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0667245 |
| CTBP2 | C-terminal binding protein 2 | -0.0626494 |
| ZFHX3 | zinc finger homeobox 3 | -0.0594423 |
| FBXO11 | F-box protein 11 | -0.0579865 |
| FNDC3B | fibronectin type III domain containing 3B | -0.057769 |
| ERBIN | erbb2 interacting protein | -0.0576855 |
| VIM | vimentin | -0.055688 |
| TULP4 | tubby like protein 4 | -0.0541541 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0533026 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0524582 |
| PHF3 | PHD finger protein 3 | -0.0512839 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0512777 |
| TCF12 | transcription factor 12 | -0.0507343 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0503977 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0499033 |
| QKI | QKI, KH domain containing, RNA binding | -0.0496353 |
| RPS24 | ribosomal protein S24 | -0.0488315 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0483821 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0480233 |
| ANKRD12 | ankyrin repeat domain 12 | -0.047962 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.04785 |
| ANO6 | anoctamin 6 | -0.0477018 |
| CANX | calnexin | -0.0473737 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0468813 |
| SBF2 | SET binding factor 2 | -0.0467998 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0461397 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0460528 |
| SIK3 | SIK family kinase 3 | -0.0458801 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0455618 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.0455184 |
| SPAG9 | sperm associated antigen 9 | -0.0449498 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.044774 |
| ZNF292 | zinc finger protein 292 | -0.0444864 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0442555 |
| NDRG1 | N-myc downstream regulated 1 | -0.0440357 |
| MICU1 | mitochondrial calcium uptake 1 | -0.0433896 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0433859 |
| MED13L | mediator complex subunit 13-like | -0.0433088 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0427952 |
| RHEB | Ras homolog enriched in brain | -0.0423495 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0415676 |
| RCOR1 | REST corepressor 1 | -0.0414888 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.041223 |
| PDE10A | phosphodiesterase 10A | -0.0408499 |
| RPL34 | ribosomal protein L34 | -0.0406146 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.040194 |
| HBP1 | HMG-box transcription factor 1 | -0.0401354 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0398682 |
| MYOF | myoferlin | -0.0397833 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.0396691 |
| MT2A | metallothionein 2A | -0.0394855 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0391749 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0382926 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0381704 |
| UST | uronyl-2-sulfotransferase | -0.0381402 |
| BCOR | BCL6 corepressor | -0.0377928 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0374174 |
| IGF2 | insulin-like growth factor 2 | -0.0372783 |
| PEG10 | paternally expressed 10 | -0.0368184 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0363374 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0357957 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0355024 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0353565 |
| PARD3 | par-3 family cell polarity regulator | -0.0352818 |
| GOLGA4 | golgin A4 | -0.0351062 |
| ATF6 | activating transcription factor 6 | -0.0348175 |
| FOXO3 | forkhead box O3 | -0.034781 |
| RPS23 | ribosomal protein S23 | -0.0343147 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0342624 |
| PTK2 | protein tyrosine kinase 2 | -0.0338704 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0332877 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0330632 |
| AK1 | adenylate kinase 1 | -0.0328033 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0326697 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0323874 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0321281 |
| POU2F1 | POU class 2 homeobox 1 | -0.0320738 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0319702 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0319344 |
| NF1 | neurofibromin 1 | -0.0318675 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0318435 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0315609 |
| SPPL3 | signal peptide peptidase like 3 | -0.0315575 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0309544 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.030782 |
| RPLP1 | ribosomal protein, large, P1 | -0.0306413 |
