| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ralimetinib dimesylate perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ralimetinib dimesylate_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EFNA5 | ephrin-A5 | 0.0735651 |
| NDRG1 | N-myc downstream regulated 1 | 0.0705628 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0635393 |
| VIM | vimentin | 0.0620124 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0579863 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0544355 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0519812 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0511391 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0500446 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.04923 |
| ASPH | aspartate beta-hydroxylase | 0.0491363 |
| FAM13A | family with sequence similarity 13, member A | 0.0462541 |
| FMNL2 | formin-like 2 | 0.0436453 |
| HPCAL1 | hippocalcin-like 1 | 0.043393 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0431962 |
| JMJD1C | jumonji domain containing 1C | 0.0423854 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0422907 |
| ITGA6 | integrin, alpha 6 | 0.0409059 |
| YAP1 | Yes-associated protein 1 | 0.0406811 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0406255 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0398161 |
| RPS12 | ribosomal protein S12 | 0.0392946 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0391309 |
| PLEC | plectin | 0.0384906 |
| ZNF292 | zinc finger protein 292 | 0.0377475 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0375051 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0369181 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0367004 |
| RPL37A | ribosomal protein L37a | 0.0362308 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0353346 |
| SMAD3 | SMAD family member 3 | 0.0348229 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0347792 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0337268 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0329029 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0325713 |
| NEK7 | NIMA-related kinase 7 | 0.0325596 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0323199 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0319927 |
| MED13L | mediator complex subunit 13-like | 0.0314482 |
| RPS2 | ribosomal protein S2 | 0.0313954 |
| SLTM | SAFB-like, transcription modulator | 0.0313038 |
| ATP13A3 | ATPase type 13A3 | 0.0308517 |
| RPS8 | ribosomal protein S8 | 0.0307544 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0304525 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0297451 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0296742 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0293831 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0290699 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0290115 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0289997 |
| PARD3 | par-3 family cell polarity regulator | 0.028785 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0282159 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0281283 |
| NPTN | neuroplastin | 0.0281263 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.027669 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0275676 |
| FAM3C | family with sequence similarity 3, member C | 0.0274706 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.027411 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0270934 |
| TGM2 | transglutaminase 2 | 0.027071 |
| OGA | O-GlcNAcase | 0.0270138 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0269694 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.026831 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.0267551 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0267175 |
| ITGAV | integrin, alpha V | 0.0266571 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0266469 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0265604 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0264734 |
| SEPTIN7 | septin 7 | 0.0263941 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.026035 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0259362 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | 0.0258577 |
| CDCP1 | CUB domain containing protein 1 | 0.0254425 |
| PRELID2 | PRELI domain containing 2 | 0.0254099 |
| CAPRIN2 | caprin family member 2 | 0.02515 |
| APP | amyloid beta (A4) precursor protein | 0.0251027 |
| ANO6 | anoctamin 6 | 0.0250576 |
| RPS20 | ribosomal protein S20 | 0.0249102 |
| SBF2 | SET binding factor 2 | 0.0248992 |
| NCKAP1 | NCK-associated protein 1 | 0.0248502 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0248115 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0247725 |
| CCDC88A | coiled-coil domain containing 88A | 0.0247645 |
| XPO1 | exportin 1 | 0.0246445 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0241772 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0240831 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0239631 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0239408 |
| RPS17 | ribosomal protein S17 | 0.0239027 |
| CD47 | CD47 molecule | 0.02378 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0237772 |
| AFDN | afadin, adherens junction formation factor | 0.0235572 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0235282 |
| CPNE8 | copine VIII | 0.0231582 |
| RPS3 | ribosomal protein S3 | 0.0231383 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0230791 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0229353 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.0227767 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.022694 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.207405 |
| LMO7 | LIM domain 7 | -0.199997 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.128179 |
| SLC35F3 | solute carrier family 35, member F3 | -0.124953 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.115836 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.114152 |
| LAMA4 | laminin, alpha 4 | -0.106793 |
| UBC | ubiquitin C | -0.0996781 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0902101 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0895944 |
| AHNAK | AHNAK nucleoprotein | -0.0892163 |
| NPSR1 | neuropeptide S receptor 1 | -0.0888789 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0883853 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0865587 |
| EGFR | epidermal growth factor receptor | -0.0847499 |
| CD2AP | CD2-associated protein | -0.0775666 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.076041 |
| ACTG1 | actin gamma 1 | -0.0701302 |
| MUC17 | mucin 17, cell surface associated | -0.0696328 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0648814 |
| EMP1 | epithelial membrane protein 1 | -0.0641829 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0609109 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0602635 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0600186 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.059405 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0590822 |
| FBXO11 | F-box protein 11 | -0.0590344 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0559366 |
| DSG2 | desmoglein 2 | -0.0555096 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0552517 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0549226 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0547429 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0539257 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0538672 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0514486 |
| PRSS3 | protease, serine, 3 | -0.0513057 |
| RCOR1 | REST corepressor 1 | -0.0502757 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | -0.0499258 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0498088 |
| TXNRD1 | thioredoxin reductase 1 | -0.0492502 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0471795 |
| POTEF | POTE ankyrin domain family, member F | -0.046354 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.046205 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0459596 |
| RASAL2 | RAS protein activator like 2 | -0.0455318 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0448121 |
| PERP | PERP, TP53 apoptosis effector | -0.0436984 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0436483 |
| EZR | ezrin | -0.0430701 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0427665 |
| S100A10 | S100 calcium binding protein A10 | -0.0423642 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.0422763 |
| TMSB10 | thymosin beta 10 | -0.0420482 |
| ARF4 | ADP-ribosylation factor 4 | -0.0415746 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0414132 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0411333 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0404821 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0399779 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0398661 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.0398079 |
| LAMB3 | laminin, beta 3 | -0.0397385 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0393325 |
| LAMC2 | laminin, gamma 2 | -0.0391643 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0388059 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0386067 |
| MXD1 | MAX dimerization protein 1 | -0.0385908 |
| TAOK3 | TAO kinase 3 | -0.0378701 |
| KRT18 | keratin 18, type I | -0.0378663 |
| IER3 | immediate early response 3 | -0.0372765 |
| KRT8 | keratin 8, type II | -0.0371994 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0368672 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -0.0367873 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0365175 |
| HDLBP | high density lipoprotein binding protein | -0.0364938 |
| MCU | mitochondrial calcium uniporter | -0.0364398 |
| OXSR1 | oxidative stress responsive 1 | -0.0356281 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0350005 |
| PGK1 | phosphoglycerate kinase 1 | -0.0343401 |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 | -0.0337253 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0336052 |
| RIGI | RNA sensor RIG-I | -0.0331696 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.032541 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0324713 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.032046 |
| RESF1 | retroelement silencing factor 1 | -0.0316579 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0304821 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | -0.0303294 |
| SAV1 | salvador family WW domain containing protein 1 | -0.0302736 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0302158 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0301568 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0299881 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0297182 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.029491 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | -0.0292068 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0289966 |
| S100A4 | S100 calcium binding protein A4 | -0.0282773 |
| TMEM45B | transmembrane protein 45B | -0.0282413 |
| COL17A1 | collagen, type XVII, alpha 1 | -0.0281214 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.027915 |
| NBEAL1 | neurobeachin-like 1 | -0.0277524 |
