| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ralimetinib dimesylate perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ralimetinib dimesylate_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.114948 |
| RPS12 | ribosomal protein S12 | 0.0743373 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0713253 |
| RPS3 | ribosomal protein S3 | 0.0691012 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0669587 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0651787 |
| ZNF292 | zinc finger protein 292 | 0.0643324 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.061531 |
| RPS6 | ribosomal protein S6 | 0.0598046 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0587866 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0581379 |
| ZNF608 | zinc finger protein 608 | 0.0568723 |
| DST | dystonin | 0.056335 |
| JMJD1C | jumonji domain containing 1C | 0.0562684 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.055355 |
| SET | SET nuclear proto-oncogene | 0.054102 |
| PTMA | prothymosin, alpha | 0.0532655 |
| XPO1 | exportin 1 | 0.0524858 |
| ARFGEF3 | ARFGEF family member 3 | 0.0507419 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.049813 |
| RPL37A | ribosomal protein L37a | 0.0494554 |
| FMNL2 | formin-like 2 | 0.0488912 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0487988 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0479124 |
| MATR3 | matrin 3 | 0.0478736 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0476663 |
| NEBL | nebulette | 0.0476414 |
| ENO1 | enolase 1, (alpha) | 0.047391 |
| ATRN | attractin | 0.0458591 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0455041 |
| NUP58 | nucleoporin 58 | 0.0451572 |
| KIF5B | kinesin family member 5B | 0.0448569 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0446567 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0443677 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.044353 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0439454 |
| COL5A2 | collagen, type V, alpha 2 | 0.0432832 |
| ATP11A | ATPase, class VI, type 11A | 0.043209 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0424536 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0417385 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0407165 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0404481 |
| RPS17 | ribosomal protein S17 | 0.040109 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0393442 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.038829 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | 0.0388048 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0382473 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0381819 |
| ENAH | enabled homolog (Drosophila) | 0.0380613 |
| TNPO1 | transportin 1 | 0.0374089 |
| EFNA5 | ephrin-A5 | 0.0373051 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0369464 |
| RPL26 | ribosomal protein L26 | 0.0365522 |
| NFIA | nuclear factor I/A | 0.0364314 |
| RPL13A | ribosomal protein L13a | 0.0358051 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.0352325 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0350148 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0348709 |
| OGA | O-GlcNAcase | 0.0347897 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0346911 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.0346879 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0346045 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0345455 |
| MED13L | mediator complex subunit 13-like | 0.0341589 |
| GRID2 | glutamate receptor, ionotropic, delta 2 | 0.0334568 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0334395 |
| CADM2 | cell adhesion molecule 2 | 0.0333744 |
| RPL12 | ribosomal protein L12 | 0.0332762 |
| PCBP2 | poly(rC) binding protein 2 | 0.0331433 |
| RPL18 | ribosomal protein L18 | 0.0331327 |
| FAM162A | family with sequence similarity 162, member A | 0.0331121 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0326846 |
| KIF13A | kinesin family member 13A | 0.0325283 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0324124 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | 0.0323246 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0321354 |
| ATP5F1A | ATP synthase F1 subunit alpha | 0.0320211 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0319579 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0314757 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0314727 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0313772 |
| FNBP1L | formin binding protein 1-like | 0.0311117 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0311112 |
| WDR43 | WD repeat domain 43 | 0.0310659 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.030409 |
| RPL7 | ribosomal protein L7 | 0.0302851 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0301929 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0300135 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0299821 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | 0.0299812 |
| NGLY1 | N-glycanase 1 | 0.0299722 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0299641 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0298854 |
| YEATS2 | YEATS domain containing 2 | 0.0297313 |
| WWC2 | WW and C2 domain containing 2 | 0.0295903 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0294862 |
| MEF2A | myocyte enhancer factor 2A | 0.0293959 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0292569 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0291795 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0285133 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.231485 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.130501 |
| RAD51B | RAD51 paralog B | -0.122312 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0841558 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0757253 |
| RIGI | RNA sensor RIG-I | -0.0674849 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0671669 |
| TENM3 | teneurin transmembrane protein 3 | -0.0664296 |
| ACTG1 | actin gamma 1 | -0.0635278 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0615532 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0546555 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0543133 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0465903 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0464582 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0433381 |
| EGR1 | early growth response 1 | -0.0403017 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.036767 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0350468 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0338296 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0335508 |
| H1-0 | H1.0 linker histone | -0.0333244 |
| SETX | senataxin | -0.0316534 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0308306 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0297764 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0296828 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0291339 |
| DENND1A | DENN/MADD domain containing 1A | -0.0273785 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0270633 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.0264021 |
| FUS | FUS RNA binding protein | -0.0262479 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0261555 |
| FBXO11 | F-box protein 11 | -0.0259933 |
| MT2A | metallothionein 2A | -0.0257943 |
| HMGB1 | high mobility group box 1 | -0.0257738 |
| ZNF644 | zinc finger protein 644 | -0.0242733 |
| PFN1 | profilin 1 | -0.0241378 |
| RCC1 | regulator of chromosome condensation 1 | -0.0236504 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | -0.0229791 |
| AGO2 | argonaute RISC catalytic component 2 | -0.022622 |
| VCL | vinculin | -0.0224738 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0222235 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0222194 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0221637 |
| TAPBP | TAP binding protein (tapasin) | -0.0221235 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0218761 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.021636 |
| CDK12 | cyclin-dependent kinase 12 | -0.0212928 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0208702 |
| GLG1 | golgi glycoprotein 1 | -0.0205962 |
| LIN28B | lin-28 homolog B (C. elegans) | -0.0205283 |
| SRSF3 | serine/arginine-rich splicing factor 3 | -0.0202114 |
| HDAC4 | histone deacetylase 4 | -0.0198926 |
| RPL28 | ribosomal protein L28 | -0.0198283 |
| RPS15 | ribosomal protein S15 | -0.0195897 |
| EXOC4 | exocyst complex component 4 | -0.0195689 |
| ATP9A | ATPase, class II, type 9A | -0.019503 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0194942 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0194746 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0191704 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 | -0.0190999 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0188994 |
| CANX | calnexin | -0.0187491 |
| MLIP | muscular LMNA-interacting protein | -0.0185587 |
| MASTL | microtubule associated serine/threonine kinase-like | -0.0185377 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0185228 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0183087 |
| SALL4 | spalt-like transcription factor 4 | -0.0181028 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0180032 |
| INTS6 | integrator complex subunit 6 | -0.0179519 |
| UBC | ubiquitin C | -0.0178814 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0176275 |
| NDRG1 | N-myc downstream regulated 1 | -0.0173354 |
| NRG1 | neuregulin 1 | -0.0173155 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0171544 |
| ZNF407 | zinc finger protein 407 | -0.0170486 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0167492 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0166212 |
| MSH4 | mutS homolog 4 | -0.016614 |
| KDM6B | lysine (K)-specific demethylase 6B | -0.0165897 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0165145 |
| HCFC1 | host cell factor C1 | -0.0164261 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0162886 |
| CARS1 | cysteinyl-tRNA synthetase 1 | -0.0161851 |
| CCDC91 | coiled-coil domain containing 91 | -0.0161849 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0161757 |
| SNX14 | sorting nexin 14 | -0.0160934 |
| FASN | fatty acid synthase | -0.015938 |
| NHLRC2 | NHL repeat containing 2 | -0.0157046 |
| ATG7 | autophagy related 7 | -0.0156373 |
| RPS11 | ribosomal protein S11 | -0.0155857 |
| ENOSF1 | enolase superfamily member 1 | -0.0154283 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | -0.0153414 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0153255 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0151882 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0151398 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0151087 |
| WDR27 | WD repeat domain 27 | -0.0150732 |
| TET3 | tet methylcytosine dioxygenase 3 | -0.0150035 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | -0.0148828 |
| TUBB | tubulin, beta class I | -0.0148796 |
