| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ralimetinib dimesylate perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ralimetinib dimesylate_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.0738358 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0405965 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.028408 |
| PCDH7 | protocadherin 7 | 0.0267377 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0250546 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0232959 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0200232 |
| RPS12 | ribosomal protein S12 | 0.0195564 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0183671 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0182638 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0181538 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0171555 |
| PRELID2 | PRELI domain containing 2 | 0.0169702 |
| ATXN1 | ataxin 1 | 0.0168401 |
| STAMBPL1 | STAM binding protein-like 1 | 0.0167089 |
| UTRN | utrophin | 0.0163051 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0153185 |
| GPC6 | glypican 6 | 0.0147559 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0144614 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0143211 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0142358 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0140508 |
| NBAS | neuroblastoma amplified sequence | 0.0136427 |
| GRK5 | G protein-coupled receptor kinase 5 | 0.0136066 |
| HELZ | helicase with zinc finger | 0.0130343 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0130297 |
| TMEM178B | transmembrane protein 178B | 0.0130151 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.012971 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0127879 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0126781 |
| EXOC4 | exocyst complex component 4 | 0.0125552 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0122374 |
| COPA | coatomer protein complex, subunit alpha | 0.0121507 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0119604 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0114458 |
| EFR3B | EFR3 homolog B (S. cerevisiae) | 0.0113794 |
| ASPH | aspartate beta-hydroxylase | 0.0111964 |
| NAV3 | neuron navigator 3 | 0.0111135 |
| PRKD1 | protein kinase D1 | 0.0110273 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0105703 |
| ENO1 | enolase 1, (alpha) | 0.0105371 |
| PCBP2 | poly(rC) binding protein 2 | 0.0104117 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0102338 |
| RNF145 | ring finger protein 145 | 0.0101074 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.010065 |
| NRG1 | neuregulin 1 | 0.00993343 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.00965697 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0096246 |
| RNASEH2A | ribonuclease H2, subunit A | 0.00949988 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.00937484 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.00935814 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.00934215 |
| MACROD2 | MACRO domain containing 2 | 0.00911986 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.00908938 |
| SCARB2 | scavenger receptor class B, member 2 | 0.00903391 |
| TBCD | tubulin folding cofactor D | 0.00894602 |
| COG5 | component of oligomeric golgi complex 5 | 0.00893374 |
| DPYD | dihydropyrimidine dehydrogenase | 0.00892878 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.00891991 |
| ZNF462 | zinc finger protein 462 | 0.00889012 |
| FLNA | filamin A, alpha | 0.00881913 |
| DOCK7 | dedicator of cytokinesis 7 | 0.00875679 |
| FAM120A | family with sequence similarity 120A | 0.00875631 |
| WDR43 | WD repeat domain 43 | 0.00871754 |
| HYOU1 | hypoxia up-regulated 1 | 0.00869839 |
| LNPK | lunapark, ER junction formation factor | 0.00860887 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.00860689 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.00859721 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0085968 |
| COG6 | component of oligomeric golgi complex 6 | 0.00839494 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.00836718 |
| ETV6 | ets variant 6 | 0.00835198 |
| TNIK | TRAF2 and NCK interacting kinase | 0.00826525 |
| SRGAP2C | SLIT-ROBO Rho GTPase activating protein 2C | 0.00825416 |
| ZNF451 | zinc finger protein 451 | 0.00824947 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.00823858 |
| MANBA | mannosidase, beta A, lysosomal | 0.00819373 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.00806226 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 0.00802761 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.0080072 |
| TMEM14B | transmembrane protein 14B | 0.00798693 |
| RNF150 | ring finger protein 150 | 0.00798333 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 | 0.00795393 |
| VWA8 | von Willebrand factor A domain containing 8 | 0.00791957 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00782896 |
| RNF217 | ring finger protein 217 | 0.00781448 |
| RRM2B | ribonucleotide reductase M2 B (TP53 inducible) | 0.00779407 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.00778135 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.00777724 |
| LIMA1 | LIM domain and actin binding 1 | 0.00773261 |
| MYO1B | myosin IB | 0.00773104 |
| RPS17 | ribosomal protein S17 | 0.0076947 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.00768166 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0076538 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.00764898 |
| PTCHD4 | patched domain containing 4 | 0.00762468 |
| ANKRD36B | ankyrin repeat domain 36B | 0.00760398 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.00759264 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.00754532 |
| VEGFA | vascular endothelial growth factor A | 0.00750775 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.487165 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.417416 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.141695 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.101176 |
| NDRG1 | N-myc downstream regulated 1 | -0.089256 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0804027 |
| VGF | VGF nerve growth factor inducible | -0.0687769 |
| ACTG1 | actin gamma 1 | -0.0684766 |
| FMN1 | formin 1 | -0.0672571 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0640841 |
| CALU | calumenin | -0.0609287 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0549191 |
| IER3 | immediate early response 3 | -0.0519293 |
| A2M | alpha-2-macroglobulin | -0.0515653 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0515302 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0488558 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0472715 |
| TNNC1 | troponin C type 1 (slow) | -0.0468645 |
| GDF15 | growth differentiation factor 15 | -0.0458254 |
| COL19A1 | collagen, type XIX, alpha 1 | -0.0453853 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0452656 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0448002 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0437721 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0433164 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0429319 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0411129 |
| ICAM1 | intercellular adhesion molecule 1 | -0.039919 |
| MTPN | myotrophin | -0.0379045 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0366675 |
| UBC | ubiquitin C | -0.0365167 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0345488 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0344053 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0339957 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0339822 |
| HLA-B | major histocompatibility complex, class I, B | -0.0336236 |
| LAMB1 | laminin, beta 1 | -0.0333036 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0319811 |
| SFTPA2 | surfactant protein A2 | -0.0315384 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0309384 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0293229 |
| PGK1 | phosphoglycerate kinase 1 | -0.0293156 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0287085 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0273703 |
| RTN4 | reticulon 4 | -0.027279 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0270103 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0269897 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0268941 |
| TMEM123 | transmembrane protein 123 | -0.02649 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0255706 |
| CANX | calnexin | -0.025559 |
| GNAS | GNAS complex locus | -0.0252767 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0251745 |
| S100A6 | S100 calcium binding protein A6 | -0.025003 |
| FRMD4A | FERM domain containing 4A | -0.0248449 |
| ADM | adrenomedullin | -0.0248166 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0246361 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0242411 |
| CUX1 | cut-like homeobox 1 | -0.0240329 |
| GOLGA4 | golgin A4 | -0.0238129 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0236672 |
| MT1X | metallothionein 1X | -0.0234991 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0234975 |
| ATF6 | activating transcription factor 6 | -0.0234107 |
| VMP1 | vacuole membrane protein 1 | -0.0233965 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0233101 |
| WDR45B | WD repeat domain 45B | -0.023155 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0229796 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0229284 |
| RRBP1 | ribosome binding protein 1 | -0.0228661 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0227606 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0224827 |
| MITF | microphthalmia-associated transcription factor | -0.0222999 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | -0.0220517 |
| TMEM263 | transmembrane protein 263 | -0.0220448 |
| PTMA | prothymosin, alpha | -0.0218718 |
| CALD1 | caldesmon 1 | -0.0214857 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0212945 |
| RAB7A | RAB7A, member RAS oncogene family | -0.021063 |
| PI15 | peptidase inhibitor 15 | -0.0209318 |
| RPS2 | ribosomal protein S2 | -0.0209128 |
| EGR1 | early growth response 1 | -0.0208905 |
| IVNS1ABP | influenza virus NS1A binding protein | -0.0205358 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0203635 |
| NPR2 | natriuretic peptide receptor 2 | -0.0202657 |
| MEF2A | myocyte enhancer factor 2A | -0.0200258 |
| RHEB | Ras homolog enriched in brain | -0.0200021 |
| INSIG1 | insulin induced gene 1 | -0.0198146 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0196492 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.019649 |
| NLGN1 | neuroligin 1 | -0.0193644 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0192277 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0191478 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0189327 |
| POM121 | POM121 transmembrane nucleoporin | -0.0188168 |
| TRIM2 | tripartite motif containing 2 | -0.0186258 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0186035 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.018567 |
| ACTN4 | actinin, alpha 4 | -0.0185458 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0185203 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0184082 |
