| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ralimetinib dimesylate perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ralimetinib dimesylate_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0951323 |
| MT2A | metallothionein 2A | 0.0798546 |
| CP | ceruloplasmin (ferroxidase) | 0.064384 |
| EFNA5 | ephrin-A5 | 0.0546088 |
| B2M | beta-2-microglobulin | 0.0523486 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0490427 |
| ENO1 | enolase 1, (alpha) | 0.0490269 |
| TMSB10 | thymosin beta 10 | 0.0455035 |
| VIM | vimentin | 0.0434274 |
| SP100 | SP100 nuclear antigen | 0.0422906 |
| RPS3 | ribosomal protein S3 | 0.0416661 |
| HLA-A | major histocompatibility complex, class I, A | 0.0397635 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0361171 |
| RPL23 | ribosomal protein L23 | 0.0360256 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0353046 |
| RPL35A | ribosomal protein L35a | 0.0338368 |
| RPS17 | ribosomal protein S17 | 0.0319451 |
| BICC1 | BicC family RNA binding protein 1 | 0.0315438 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0313679 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0313529 |
| RAD51B | RAD51 paralog B | 0.0310513 |
| PRELID2 | PRELI domain containing 2 | 0.0308097 |
| LCN2 | lipocalin 2 | 0.0305491 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0297493 |
| RNF213 | ring finger protein 213 | 0.0296751 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0289963 |
| RPS12 | ribosomal protein S12 | 0.0288312 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0283477 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0276878 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0260313 |
| KLF6 | Kruppel-like factor 6 | 0.0249407 |
| MT1E | metallothionein 1E | 0.0242785 |
| PHF3 | PHD finger protein 3 | 0.0236437 |
| GPHN | gephyrin | 0.0234678 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0230147 |
| TMC5 | transmembrane channel-like 5 | 0.0229184 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0227593 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0226266 |
| CD47 | CD47 molecule | 0.0221406 |
| CDK6 | cyclin-dependent kinase 6 | 0.0218649 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0217319 |
| MX1 | MX dynamin-like GTPase 1 | 0.0215839 |
| NCKAP5 | NCK-associated protein 5 | 0.0210433 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0209483 |
| MGST1 | microsomal glutathione S-transferase 1 | 0.0209218 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0208888 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0206933 |
| FOXP1 | forkhead box P1 | 0.0196843 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0196754 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0196135 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0193618 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0193576 |
| GLIS3 | GLIS family zinc finger 3 | 0.0192195 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0191367 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0191216 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.019108 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0190961 |
| EHBP1 | EH domain binding protein 1 | 0.0189819 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.0185435 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0184677 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0184657 |
| EPHA6 | EPH receptor A6 | 0.0183094 |
| SMYD3 | SET and MYND domain containing 3 | 0.0178417 |
| TGFB2 | transforming growth factor, beta 2 | 0.0178018 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0175502 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0174804 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0173181 |
| RPS8 | ribosomal protein S8 | 0.0172651 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0172596 |
| PROM1 | prominin 1 | 0.017189 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0171678 |
| KIAA1217 | KIAA1217 | 0.0171381 |
| MYO9A | myosin IXA | 0.0169662 |
| NRG3 | neuregulin 3 | 0.016933 |
| PDGFC | platelet derived growth factor C | 0.0168693 |
| MUC4 | mucin 4, cell surface associated | 0.0167349 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0166957 |
| NRG1 | neuregulin 1 | 0.0166389 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0164876 |
| RPL31 | ribosomal protein L31 | 0.0164395 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0163603 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0163251 |
| RPS25 | ribosomal protein S25 | 0.0162937 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0161587 |
| MEIS2 | Meis homeobox 2 | 0.0160741 |
| EDN1 | endothelin 1 | 0.0160297 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0158472 |
| CD46 | CD46 molecule, complement regulatory protein | 0.015825 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0157235 |
| LOX | lysyl oxidase | 0.0156822 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0155649 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.0154248 |
| NNMT | nicotinamide N-methyltransferase | 0.0153239 |
| PCDH7 | protocadherin 7 | 0.0153084 |
| RACK1 | receptor for activated C kinase 1 | 0.0152179 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0152173 |
| RBM47 | RNA binding motif protein 47 | 0.015153 |
| KYNU | kynureninase | 0.0151414 |
| PMP22 | peripheral myelin protein 22 | 0.0151042 |
| RPL9 | ribosomal protein L9 | 0.0149471 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.307222 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.155611 |
| NDRG1 | N-myc downstream regulated 1 | -0.153839 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.132976 |
| ACTG1 | actin gamma 1 | -0.127287 |
| UBC | ubiquitin C | -0.127076 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.120736 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.102551 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0968647 |
| POTEF | POTE ankyrin domain family, member F | -0.0945068 |
| LAMC2 | laminin, gamma 2 | -0.0916889 |
| SPAG9 | sperm associated antigen 9 | -0.0812221 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0737127 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0637061 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0635161 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0616772 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0612709 |
| EZR | ezrin | -0.0607664 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0562579 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.055709 |
| LMO7 | LIM domain 7 | -0.0555439 |
| MT1X | metallothionein 1X | -0.0552414 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0549655 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0546184 |
| FLNB | filamin B, beta | -0.0533506 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0526201 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0525137 |
| HMGA1 | high mobility group AT-hook 1 | -0.0522705 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0515976 |
| CDCP1 | CUB domain containing protein 1 | -0.051251 |
| LAMA4 | laminin, alpha 4 | -0.0501816 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0496689 |
| MAP1B | microtubule-associated protein 1B | -0.0495954 |
| PTMA | prothymosin, alpha | -0.0489795 |
| DSG2 | desmoglein 2 | -0.0489718 |
| FA2H | fatty acid 2-hydroxylase | -0.0485778 |
| OPTN | optineurin | -0.048121 |
| CANX | calnexin | -0.0480093 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0476423 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0474988 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0467378 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0464788 |
| RCOR1 | REST corepressor 1 | -0.045676 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0455687 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0453373 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0451952 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0450791 |
| IER3 | immediate early response 3 | -0.0447348 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0444657 |
| S100A10 | S100 calcium binding protein A10 | -0.0440216 |
| TMSB4X | thymosin beta 4, X-linked | -0.0439439 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0437546 |
| RBM39 | RNA binding motif protein 39 | -0.0435287 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0417631 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0416833 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0411092 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0409721 |
| RAB1A | RAB1A, member RAS oncogene family | -0.040646 |
| RIOK3 | RIO kinase 3 | -0.0404336 |
| MYO5B | myosin VB | -0.0395873 |
| RPS2 | ribosomal protein S2 | -0.0388649 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0385354 |
| MXD1 | MAX dimerization protein 1 | -0.038318 |
| KRT19 | keratin 19, type I | -0.0376192 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0375453 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0372744 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0371392 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0362578 |
| CCNY | cyclin Y | -0.0362426 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0353906 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0352618 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0340365 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0337506 |
| DIAPH1 | diaphanous-related formin 1 | -0.0337486 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0335223 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0330979 |
| ANXA2 | annexin A2 | -0.0329738 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0329314 |
| JUP | junction plakoglobin | -0.0326418 |
| MEF2A | myocyte enhancer factor 2A | -0.0325511 |
| ANXA11 | annexin A11 | -0.03225 |
| PARD3 | par-3 family cell polarity regulator | -0.0318286 |
| TPM4 | tropomyosin 4 | -0.0318233 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0316493 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0314048 |
| ITGA6 | integrin, alpha 6 | -0.0309731 |
| SEC24A | SEC24 family member A | -0.0309442 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0304984 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0304704 |
| WDR45B | WD repeat domain 45B | -0.0301781 |
| PGK1 | phosphoglycerate kinase 1 | -0.0297491 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0297389 |
| ADM | adrenomedullin | -0.0296311 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0293896 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0291342 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.028816 |
| NUMB | numb homolog (Drosophila) | -0.0287074 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0286399 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0285508 |
| ASPH | aspartate beta-hydroxylase | -0.0283088 |
