| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ralimetinib dimesylate perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ralimetinib dimesylate_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.1723 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0967767 |
| PTMA | prothymosin, alpha | 0.0856157 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0801786 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0785887 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0779576 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0737526 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0706334 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0669823 |
| DPH6 | diphthamine biosynthesis 6 | 0.0655332 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0619136 |
| MSI2 | musashi RNA-binding protein 2 | 0.0607054 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0582525 |
| SMYD3 | SET and MYND domain containing 3 | 0.0572684 |
| LPIN1 | lipin 1 | 0.0569952 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0554183 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0543608 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0540915 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0532164 |
| FAM13A | family with sequence similarity 13, member A | 0.0512479 |
| MYO6 | myosin VI | 0.051195 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0510721 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0493875 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0491739 |
| HMGB2 | high mobility group box 2 | 0.0489133 |
| ZNF292 | zinc finger protein 292 | 0.0476 |
| ENAH | enabled homolog (Drosophila) | 0.0472829 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0465347 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0457702 |
| VIM | vimentin | 0.0451788 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0451624 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0451244 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.044442 |
| HELZ | helicase with zinc finger | 0.0438484 |
| DST | dystonin | 0.043633 |
| SMAD3 | SMAD family member 3 | 0.0409071 |
| WDR43 | WD repeat domain 43 | 0.0401397 |
| VCAN | versican | 0.0382135 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0381901 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | 0.038171 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0374516 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0369593 |
| SET | SET nuclear proto-oncogene | 0.0366101 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0366088 |
| XPO1 | exportin 1 | 0.0354212 |
| RPL37A | ribosomal protein L37a | 0.0352847 |
| MATR3 | matrin 3 | 0.0348385 |
| RBM20 | RNA binding motif protein 20 | 0.0348138 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0347899 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0345703 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.034514 |
| MEF2A | myocyte enhancer factor 2A | 0.0333242 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0330264 |
| OGA | O-GlcNAcase | 0.0329099 |
| PRKD1 | protein kinase D1 | 0.0328848 |
| RPS12 | ribosomal protein S12 | 0.03281 |
| JPT1 | Jupiter microtubule associated homolog 1 | 0.0326278 |
| RUNX1 | runt-related transcription factor 1 | 0.0325988 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0325733 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0323563 |
| TOP1 | topoisomerase (DNA) I | 0.0315449 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0315283 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0312415 |
| RNF145 | ring finger protein 145 | 0.0308851 |
| COG5 | component of oligomeric golgi complex 5 | 0.0306972 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0304088 |
| PTK2 | protein tyrosine kinase 2 | 0.0300974 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0300701 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.0296761 |
| RPS3 | ribosomal protein S3 | 0.0296392 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0296339 |
| NCOR2 | nuclear receptor corepressor 2 | 0.029472 |
| SEPTIN9 | septin 9 | 0.0293209 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0292092 |
| TCERG1 | transcription elongation regulator 1 | 0.0290578 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0286656 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0284404 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.028286 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.0282058 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0281563 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0280922 |
| ANXA2 | annexin A2 | 0.027902 |
| TBX2 | T-box 2 | 0.0277406 |
| CDK19 | cyclin-dependent kinase 19 | 0.0275365 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0275247 |
| RPL7 | ribosomal protein L7 | 0.0275055 |
| RPL26 | ribosomal protein L26 | 0.0274294 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0273638 |
| GPC5 | glypican 5 | 0.0273395 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.0272423 |
| KCTD3 | potassium channel tetramerization domain containing 3 | 0.0270981 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.026939 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0265461 |
| MMP2 | matrix metallopeptidase 2 | 0.0264941 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0262004 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0261579 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0260202 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0259171 |
| YEATS2 | YEATS domain containing 2 | 0.0257583 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.025693 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.34329 |
| VCL | vinculin | -0.192331 |
| EXT1 | exostosin glycosyltransferase 1 | -0.11257 |
| IGF2 | insulin-like growth factor 2 | -0.0825112 |
| LSAMP | limbic system-associated membrane protein | -0.0804743 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.07928 |
| SYT1 | synaptotagmin I | -0.0730211 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0634996 |
| MAP1B | microtubule-associated protein 1B | -0.0567607 |
| ACTG1 | actin gamma 1 | -0.0536834 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.053317 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0513533 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0504898 |
| COL1A1 | collagen, type I, alpha 1 | -0.050264 |
| NDRG1 | N-myc downstream regulated 1 | -0.0501894 |
| GLCCI1 | glucocorticoid induced 1 | -0.0491902 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0486149 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0466459 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0445279 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0428901 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0419804 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0410915 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0408582 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0403346 |
| IER3 | immediate early response 3 | -0.0389633 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0388239 |
| EGR1 | early growth response 1 | -0.0385516 |
| FRMD4A | FERM domain containing 4A | -0.0383426 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0376809 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0373162 |
| NRG1 | neuregulin 1 | -0.0370067 |
| STK38L | serine/threonine kinase 38 like | -0.03622 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.0358797 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0353519 |
| BPTF | bromodomain PHD finger transcription factor | -0.0351195 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0348934 |
| TAOK1 | TAO kinase 1 | -0.0346995 |
| FAM107B | family with sequence similarity 107, member B | -0.034556 |
| UBC | ubiquitin C | -0.0342859 |
| STC1 | stanniocalcin 1 | -0.0341682 |
| MYO1E | myosin IE | -0.0339131 |
| SYNPO2 | synaptopodin 2 | -0.0334299 |
| TLE4 | transducin-like enhancer of split 4 | -0.0330576 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0330266 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0329332 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0326273 |
| RIGI | RNA sensor RIG-I | -0.0326273 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0325214 |
| PDE10A | phosphodiesterase 10A | -0.0319765 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0319229 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0316518 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0314524 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0312486 |
| CANX | calnexin | -0.0310331 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0305777 |
| SIK2 | salt-inducible kinase 2 | -0.0303411 |
| FHL2 | four and a half LIM domains 2 | -0.0289564 |
| H1-0 | H1.0 linker histone | -0.0289434 |
| ARF1 | ADP-ribosylation factor 1 | -0.0275484 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0274612 |
| INTS6 | integrator complex subunit 6 | -0.0271585 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | -0.0271213 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.027102 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0269269 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0268729 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0264094 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0263501 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.025901 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0253277 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0252548 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0251882 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.025144 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0249606 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0248557 |
| FOXO3 | forkhead box O3 | -0.0247561 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.02471 |
| GAB2 | GRB2-associated binding protein 2 | -0.0246264 |
| PLPP1 | phospholipid phosphatase 1 | -0.0244485 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0242784 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0242739 |
| RNF150 | ring finger protein 150 | -0.0240452 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0238678 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0238325 |
| THBS1 | thrombospondin 1 | -0.0236814 |
| PER1 | period circadian clock 1 | -0.0235871 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0234595 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0233416 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0232547 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0230372 |
| IRS1 | insulin receptor substrate 1 | -0.0224974 |
| RSU1 | Ras suppressor protein 1 | -0.0224895 |
| GPATCH8 | G patch domain containing 8 | -0.0224865 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0222848 |
| TPM4 | tropomyosin 4 | -0.0222762 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0222663 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.02218 |
| ANGPT1 | angiopoietin 1 | -0.0221711 |
| RYBP | RING1 and YY1 binding protein | -0.0221061 |
| LIMA1 | LIM domain and actin binding 1 | -0.022068 |
| FERMT2 | fermitin family member 2 | -0.021909 |
