| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ralimetinib dimesylate perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ralimetinib dimesylate_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PRELID2 | PRELI domain containing 2 | 0.091686 |
| MEF2A | myocyte enhancer factor 2A | 0.088851 |
| ENO1 | enolase 1, (alpha) | 0.0769529 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0622985 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0621328 |
| MYOF | myoferlin | 0.0619828 |
| RIN2 | Ras and Rab interactor 2 | 0.0573238 |
| NRG1 | neuregulin 1 | 0.0565021 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0550647 |
| FOXP1 | forkhead box P1 | 0.054827 |
| CLU | clusterin | 0.0516825 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0481591 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.047411 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.045978 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0456995 |
| ZNF292 | zinc finger protein 292 | 0.0452784 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0445443 |
| RPS12 | ribosomal protein S12 | 0.0430698 |
| ITGA6 | integrin, alpha 6 | 0.0413897 |
| ASPH | aspartate beta-hydroxylase | 0.0407905 |
| METTL15 | methyltransferase like 15 | 0.0376024 |
| KIAA1217 | KIAA1217 | 0.036385 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0360941 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0353294 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.034221 |
| PDLIM1 | PDZ and LIM domain 1 | 0.0334557 |
| ANGPTL4 | angiopoietin-like 4 | 0.0329319 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.032609 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0323376 |
| RPS3 | ribosomal protein S3 | 0.0321919 |
| MYO10 | myosin X | 0.0319136 |
| PLAT | plasminogen activator, tissue | 0.0309462 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0305938 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.030146 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0299846 |
| DOCK5 | dedicator of cytokinesis 5 | 0.029918 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0295794 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0295765 |
| DOK5 | docking protein 5 | 0.0290846 |
| YEATS2 | YEATS domain containing 2 | 0.0289392 |
| OGA | O-GlcNAcase | 0.028294 |
| SERINC3 | serine incorporator 3 | 0.0282109 |
| PLAC8 | placenta-specific 8 | 0.0273465 |
| SOX7 | SRY (sex determining region Y)-box 7 | 0.0272425 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.027206 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0271156 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0267852 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0265027 |
| CAPRIN2 | caprin family member 2 | 0.0262402 |
| RPL21 | ribosomal protein L21 | 0.0261654 |
| SMYD3 | SET and MYND domain containing 3 | 0.025857 |
| B2M | beta-2-microglobulin | 0.0258138 |
| TPM3 | tropomyosin 3 | 0.0253347 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0249472 |
| TGM2 | transglutaminase 2 | 0.0248207 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0246934 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.024555 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0241843 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0240604 |
| CDK19 | cyclin-dependent kinase 19 | 0.0232744 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0231172 |
| USP47 | ubiquitin specific peptidase 47 | 0.0229117 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0226601 |
| KIAA0040 | KIAA0040 | 0.0225669 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0225059 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0223744 |
| OSBPL6 | oxysterol binding protein-like 6 | 0.0223265 |
| GATA6 | GATA binding protein 6 | 0.0221176 |
| C4BPB | complement component 4 binding protein, beta | 0.0221108 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0220954 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0220294 |
| CD47 | CD47 molecule | 0.0219956 |
| SET | SET nuclear proto-oncogene | 0.0218501 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0217947 |
| BCL2L1 | BCL2-like 1 | 0.0217771 |
| ANLN | anillin, actin binding protein | 0.0216643 |
| FOXO1 | forkhead box O1 | 0.0216352 |
| NEK7 | NIMA-related kinase 7 | 0.0214752 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0213844 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0212718 |
| JAG1 | jagged 1 | 0.0211285 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0211214 |
| SLTM | SAFB-like, transcription modulator | 0.0210685 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0210391 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0208056 |
| ZNF148 | zinc finger protein 148 | 0.0207587 |
| SYNJ2 | synaptojanin 2 | 0.0206048 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0206043 |
| HDAC8 | histone deacetylase 8 | 0.02056 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.020398 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0202126 |
| PDGFB | platelet-derived growth factor beta polypeptide | 0.0201117 |
| LIMA1 | LIM domain and actin binding 1 | 0.0198316 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.019782 |
| ANO6 | anoctamin 6 | 0.0197615 |
| PLEC | plectin | 0.0196737 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0196494 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.0195723 |
| LOXL2 | lysyl oxidase-like 2 | 0.019532 |
| SLC45A4 | solute carrier family 45, member 4 | 0.019502 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.248569 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.225065 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.195485 |
| LMO7 | LIM domain 7 | -0.119657 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0956712 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0950213 |
| PDLIM5 | PDZ and LIM domain 5 | -0.084593 |
| NDRG1 | N-myc downstream regulated 1 | -0.0833552 |
| INTS6 | integrator complex subunit 6 | -0.0817021 |
| S100A10 | S100 calcium binding protein A10 | -0.0795588 |
| H1-0 | H1.0 linker histone | -0.0775834 |
| POTEF | POTE ankyrin domain family, member F | -0.0702494 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0695562 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0689854 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0664534 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0627773 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0595036 |
| PLS3 | plastin 3 | -0.0587878 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0572214 |
| AHNAK | AHNAK nucleoprotein | -0.0531822 |
| ANXA2 | annexin A2 | -0.0508176 |
| EXT1 | exostosin glycosyltransferase 1 | -0.050813 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0506401 |
| PALLD | palladin, cytoskeletal associated protein | -0.0500014 |
| LAMC2 | laminin, gamma 2 | -0.0497446 |
| RCOR1 | REST corepressor 1 | -0.0484643 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.047253 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0471221 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0467809 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0464725 |
| TMSB10 | thymosin beta 10 | -0.0454748 |
| IGF2 | insulin-like growth factor 2 | -0.0454568 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0454045 |
| ANXA1 | annexin A1 | -0.0440828 |
| RIGI | RNA sensor RIG-I | -0.0439739 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.043233 |
| PTMA | prothymosin, alpha | -0.0428907 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0420482 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0416856 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0416176 |
| RPS21 | ribosomal protein S21 | -0.0414784 |
| ARF1 | ADP-ribosylation factor 1 | -0.0412231 |
| RASAL2 | RAS protein activator like 2 | -0.0408852 |
| MTSS1 | metastasis suppressor 1 | -0.0405114 |
| RPL8 | ribosomal protein L8 | -0.0384641 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.038001 |
| STC1 | stanniocalcin 1 | -0.0377292 |
| ACTN4 | actinin, alpha 4 | -0.0376883 |
| TMSB4X | thymosin beta 4, X-linked | -0.0374469 |
| WASF2 | WAS protein family, member 2 | -0.0370782 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0366936 |
| CD44 | CD44 molecule (Indian blood group) | -0.0363308 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0363155 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0361294 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0353971 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0352691 |
| SQLE | squalene epoxidase | -0.0348818 |
| CANX | calnexin | -0.0346023 |
| GNAS | GNAS complex locus | -0.0344877 |
| SULF2 | sulfatase 2 | -0.0341026 |
| ACTG1 | actin gamma 1 | -0.0337577 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0334674 |
| FBXO11 | F-box protein 11 | -0.0327937 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0325306 |
| MT1X | metallothionein 1X | -0.0324498 |
| UBC | ubiquitin C | -0.0315789 |
| EMP1 | epithelial membrane protein 1 | -0.0311641 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0308631 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0308161 |
| HMGA2 | high mobility group AT-hook 2 | -0.0304667 |
| SQSTM1 | sequestosome 1 | -0.0303525 |
| SPAG9 | sperm associated antigen 9 | -0.0302216 |
| DGKH | diacylglycerol kinase, eta | -0.0293269 |
| RBM39 | RNA binding motif protein 39 | -0.0292926 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0292831 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0292255 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0287467 |
| RPLP1 | ribosomal protein, large, P1 | -0.0286464 |
| THBD | thrombomodulin | -0.0284566 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.0284407 |
| RRBP1 | ribosome binding protein 1 | -0.0284346 |
| PODXL | podocalyxin-like | -0.0283899 |
| CLIC4 | chloride intracellular channel 4 | -0.0283569 |
| COPA | coatomer protein complex, subunit alpha | -0.0283544 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0283405 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0281617 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0281211 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0274573 |
| GUK1 | guanylate kinase 1 | -0.0267219 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0265175 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0263701 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.026015 |
| EGR1 | early growth response 1 | -0.0260076 |
| RAI14 | retinoic acid induced 14 | -0.0258935 |
| EZR | ezrin | -0.0258877 |
| SETX | senataxin | -0.025795 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0256575 |
| HMGA1 | high mobility group AT-hook 1 | -0.0255855 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0250468 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0246365 |
