| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ralimetinib dimesylate perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ralimetinib dimesylate_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.130072 |
| ATP13A3 | ATPase type 13A3 | 0.123463 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0947872 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.087726 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0771603 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0729824 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0714048 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0605191 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0574651 |
| ZNF841 | zinc finger protein 841 | 0.0561773 |
| SLC12A8 | solute carrier family 12, member 8 | 0.052271 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0482458 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.047558 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0461577 |
| NUP153 | nucleoporin 153kDa | 0.0456047 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0429059 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0428708 |
| ANXA1 | annexin A1 | 0.0427116 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0420703 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0411079 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0410079 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0404626 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0398625 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0391641 |
| RBM39 | RNA binding motif protein 39 | 0.0386589 |
| ZNF292 | zinc finger protein 292 | 0.0381475 |
| TGFB2 | transforming growth factor, beta 2 | 0.0374611 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0374498 |
| HMGB2 | high mobility group box 2 | 0.0367616 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0366293 |
| PDS5B | PDS5 cohesin associated factor B | 0.0366116 |
| YEATS2 | YEATS domain containing 2 | 0.0365313 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0362072 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0349106 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0346904 |
| AFAP1 | actin filament associated protein 1 | 0.0345138 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0344118 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0343317 |
| ZFR | zinc finger RNA binding protein | 0.0340467 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0331578 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0329043 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0320404 |
| NUP58 | nucleoporin 58 | 0.0317599 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0308865 |
| DENND4C | DENN/MADD domain containing 4C | 0.0306414 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0305459 |
| DIAPH3 | diaphanous-related formin 3 | 0.0304089 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0300104 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | 0.0299246 |
| NCKAP1 | NCK-associated protein 1 | 0.0297342 |
| DENND5A | DENN/MADD domain containing 5A | 0.0296035 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0293291 |
| STK4 | serine/threonine kinase 4 | 0.0293123 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0292487 |
| SUCO | SUN domain containing ossification factor | 0.0290805 |
| TNPO1 | transportin 1 | 0.0288776 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0282771 |
| RLF | rearranged L-myc fusion | 0.0281631 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0277409 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0276348 |
| SULF1 | sulfatase 1 | 0.027521 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0273164 |
| PDE10A | phosphodiesterase 10A | 0.0269447 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0268243 |
| SET | SET nuclear proto-oncogene | 0.0264326 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.0263058 |
| NOP58 | NOP58 ribonucleoprotein | 0.026205 |
| ECT2 | epithelial cell transforming 2 | 0.0259947 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0258749 |
| OGA | O-GlcNAcase | 0.0256176 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0255911 |
| PLCB4 | phospholipase C, beta 4 | 0.0254568 |
| MATR3 | matrin 3 | 0.0254028 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0253672 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0253222 |
| TMEM165 | transmembrane protein 165 | 0.0252972 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0247353 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0247143 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0244774 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0244375 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0241853 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.0241638 |
| TPD52 | tumor protein D52 | 0.0241102 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0237325 |
| CCDC14 | coiled-coil domain containing 14 | 0.0237262 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0236429 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0235058 |
| OSMR | oncostatin M receptor | 0.0234477 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0233419 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.023236 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0230383 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0230169 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0229687 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0229044 |
| MLF1 | myeloid leukemia factor 1 | 0.0228405 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0227576 |
| WWC2 | WW and C2 domain containing 2 | 0.0224879 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.0224105 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0222874 |
| TEX10 | testis expressed 10 | 0.0218741 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.308134 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.188303 |
| MT2A | metallothionein 2A | -0.169021 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.139308 |
| HLA-B | major histocompatibility complex, class I, B | -0.137819 |
| POTEF | POTE ankyrin domain family, member F | -0.127464 |
| FTL | ferritin, light polypeptide | -0.102373 |
| ASPH | aspartate beta-hydroxylase | -0.100477 |
| FN1 | fibronectin 1 | -0.0957174 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0909874 |
| INTS6 | integrator complex subunit 6 | -0.0883572 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0828304 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0817434 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0725125 |
| ACTG1 | actin gamma 1 | -0.0689616 |
| NDRG1 | N-myc downstream regulated 1 | -0.0647165 |
| MT1X | metallothionein 1X | -0.0618787 |
| DEK | DEK proto-oncogene | -0.0538271 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0511063 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0490837 |
| CD44 | CD44 molecule (Indian blood group) | -0.0465387 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0461076 |
| CLIC4 | chloride intracellular channel 4 | -0.0433375 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0420885 |
| TLE4 | transducin-like enhancer of split 4 | -0.0416857 |
| S100A10 | S100 calcium binding protein A10 | -0.0408149 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0401476 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0401202 |
| AHNAK | AHNAK nucleoprotein | -0.0399961 |
| MAP1B | microtubule-associated protein 1B | -0.039587 |
| RPS6 | ribosomal protein S6 | -0.0384439 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0383447 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0372791 |
| VCL | vinculin | -0.035133 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.03493 |
| CENPF | centromere protein F, 350/400kDa | -0.0341941 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0341776 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0341541 |
| RAD51B | RAD51 paralog B | -0.0338165 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0336797 |
| CCND1 | cyclin D1 | -0.0334699 |
| EGFR | epidermal growth factor receptor | -0.0331709 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0323054 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0318586 |
| TPM1 | tropomyosin 1 (alpha) | -0.0313686 |
| PODXL | podocalyxin-like | -0.0313514 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0307395 |
| TPM4 | tropomyosin 4 | -0.0303434 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0300646 |
| PKM | pyruvate kinase, muscle | -0.0300483 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0296684 |
| ADM | adrenomedullin | -0.0291905 |
| B2M | beta-2-microglobulin | -0.0288614 |
| RPS13 | ribosomal protein S13 | -0.0287201 |
| UBC | ubiquitin C | -0.0286447 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0285811 |
| HMGA1 | high mobility group AT-hook 1 | -0.0283687 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0282201 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0279901 |
| FOSL1 | FOS-like antigen 1 | -0.0278625 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0275921 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0275513 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0273966 |
| MSN | moesin | -0.0271163 |
| SEPTIN9 | septin 9 | -0.0266364 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.0265699 |
| TAPBP | TAP binding protein (tapasin) | -0.0265074 |
| EGR1 | early growth response 1 | -0.0264584 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0264082 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0263996 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0263648 |
| MCL1 | myeloid cell leukemia 1 | -0.0263529 |
| ATXN1 | ataxin 1 | -0.0263354 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0262136 |
| WASF2 | WAS protein family, member 2 | -0.0261548 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0261152 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0255233 |
| TUBB | tubulin, beta class I | -0.0254581 |
| TAOK1 | TAO kinase 1 | -0.0254148 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0249735 |
| NABP1 | nucleic acid binding protein 1 | -0.0247331 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0247296 |
| CALD1 | caldesmon 1 | -0.0247212 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0243011 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0240494 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0239927 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0239611 |
| RHOA | ras homolog family member A | -0.0239198 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0236652 |
| PFN1 | profilin 1 | -0.0236384 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0234563 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0230188 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0229784 |
| WNT5B | wingless-type MMTV integration site family, member 5B | -0.0229152 |
| RPL35A | ribosomal protein L35a | -0.0226104 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0224964 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | -0.0223597 |
| RSU1 | Ras suppressor protein 1 | -0.0222978 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0220145 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0219062 |
