| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ralimetinib dimesylate perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ralimetinib dimesylate_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.114382 |
| HYOU1 | hypoxia up-regulated 1 | 0.0965491 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0873085 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0866613 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0758136 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0653433 |
| EHBP1 | EH domain binding protein 1 | 0.0641018 |
| ASPH | aspartate beta-hydroxylase | 0.0635275 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0620206 |
| FNDC3B | fibronectin type III domain containing 3B | 0.060693 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0599659 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0569162 |
| ZNF292 | zinc finger protein 292 | 0.0569067 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0565278 |
| ANLN | anillin, actin binding protein | 0.0537294 |
| OXR1 | oxidation resistance 1 | 0.053661 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0535973 |
| FAM13A | family with sequence similarity 13, member A | 0.0525696 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0519451 |
| RBM39 | RNA binding motif protein 39 | 0.0509827 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.049434 |
| RAD51B | RAD51 paralog B | 0.048604 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0466506 |
| EXOC4 | exocyst complex component 4 | 0.0460729 |
| MECOM | MDS1 and EVI1 complex locus | 0.0458052 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0455381 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0445808 |
| DST | dystonin | 0.0445245 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0440602 |
| PRELID2 | PRELI domain containing 2 | 0.0437018 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0432698 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0431074 |
| NF1 | neurofibromin 1 | 0.0417219 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0412557 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0404222 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0398397 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0398013 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0397795 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0396434 |
| RPS3 | ribosomal protein S3 | 0.0393417 |
| CDK19 | cyclin-dependent kinase 19 | 0.03913 |
| HKDC1 | hexokinase domain containing 1 | 0.0390845 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0390827 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0389686 |
| MED13 | mediator complex subunit 13 | 0.0389252 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0383598 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.038245 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0372777 |
| FRMD5 | FERM domain containing 5 | 0.0362282 |
| CCNY | cyclin Y | 0.0359296 |
| PHF3 | PHD finger protein 3 | 0.0358992 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0358932 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0358273 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0354377 |
| SETD5 | SET domain containing 5 | 0.0353025 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.035113 |
| FNIP1 | folliculin interacting protein 1 | 0.0344501 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0343585 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0343504 |
| CAPN8 | calpain 8 | 0.0343368 |
| MYOF | myoferlin | 0.0341284 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0338616 |
| TNRC6B | trinucleotide repeat containing 6B | 0.033659 |
| THOC2 | THO complex 2 | 0.0336571 |
| SEC24D | SEC24 family member D | 0.0336561 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0326986 |
| HMGB2 | high mobility group box 2 | 0.032543 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0322584 |
| FAT1 | FAT atypical cadherin 1 | 0.032233 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0321845 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0321641 |
| SSR1 | signal sequence receptor, alpha | 0.0317694 |
| MEF2A | myocyte enhancer factor 2A | 0.0315469 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0314016 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0312241 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0311278 |
| ATM | ATM serine/threonine kinase | 0.0311266 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.0311015 |
| GPHN | gephyrin | 0.0310421 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0309921 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0307203 |
| JMJD1C | jumonji domain containing 1C | 0.0305961 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0302827 |
| CEP57 | centrosomal protein 57kDa | 0.0302157 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0301653 |
| PTMA | prothymosin, alpha | 0.0299294 |
| SETD2 | SET domain containing 2 | 0.0298209 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0296254 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0293371 |
| TES | testin LIM domain protein | 0.0292061 |
| YEATS2 | YEATS domain containing 2 | 0.0291481 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0291073 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0289617 |
| GOLGB1 | golgin B1 | 0.0287546 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.028644 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0285976 |
| SSH2 | slingshot protein phosphatase 2 | 0.0284811 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0284262 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0283493 |
| RPL18 | ribosomal protein L18 | 0.0283146 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.27565 |
| NPSR1 | neuropeptide S receptor 1 | -0.126323 |
| LOC112694756 | uncharaterized LOC112694756 | -0.097604 |
| POTEF | POTE ankyrin domain family, member F | -0.0899016 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0788268 |
| AGR2 | anterior gradient 2 | -0.078425 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0747595 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0738296 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0709901 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0699503 |
| RPS6 | ribosomal protein S6 | -0.0642545 |
| LYZ | lysozyme | -0.0611192 |
| ACTG1 | actin gamma 1 | -0.0510841 |
| KRT19 | keratin 19, type I | -0.0503686 |
| PGK1 | phosphoglycerate kinase 1 | -0.0477024 |
| S100A10 | S100 calcium binding protein A10 | -0.0471631 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0449314 |
| EMP1 | epithelial membrane protein 1 | -0.0446709 |
| UBC | ubiquitin C | -0.0439204 |
| MUC1 | mucin 1, cell surface associated | -0.0433381 |
| CLDN7 | claudin 7 | -0.0429709 |
| INSIG1 | insulin induced gene 1 | -0.0427955 |
| PRSS3 | protease, serine, 3 | -0.0425517 |
| H1-0 | H1.0 linker histone | -0.041867 |
| VEGFA | vascular endothelial growth factor A | -0.0417554 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0412196 |
| GPX2 | glutathione peroxidase 2 | -0.0408816 |
| KRT8 | keratin 8, type II | -0.040795 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0392994 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0380341 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0373319 |
| RPL35A | ribosomal protein L35a | -0.0370522 |
| JUP | junction plakoglobin | -0.0364564 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0363312 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0362654 |
| CLDN4 | claudin 4 | -0.0360587 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0342568 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.033321 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | -0.0323925 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0317095 |
| RPL8 | ribosomal protein L8 | -0.0304116 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0304036 |
| PKM | pyruvate kinase, muscle | -0.0282161 |
| DEK | DEK proto-oncogene | -0.0281112 |
| EGR1 | early growth response 1 | -0.028008 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0276052 |
| TPM4 | tropomyosin 4 | -0.0274563 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.0273499 |
| ITGA6 | integrin, alpha 6 | -0.0271848 |
| S100A9 | S100 calcium binding protein A9 | -0.0267165 |
| SNX9 | sorting nexin 9 | -0.0266098 |
| S100P | S100 calcium binding protein P | -0.0265446 |
| RPS25 | ribosomal protein S25 | -0.0264592 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0264407 |
| ANXA11 | annexin A11 | -0.0264367 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0263886 |
| TSPAN3 | tetraspanin 3 | -0.0263678 |
| ANXA2 | annexin A2 | -0.0259111 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0255669 |
| FASN | fatty acid synthase | -0.0252555 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0252435 |
| YBX1 | Y box binding protein 1 | -0.0252322 |
| RPL34 | ribosomal protein L34 | -0.0251604 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.025104 |
| KRT18 | keratin 18, type I | -0.0250843 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0249122 |
| RPS11 | ribosomal protein S11 | -0.0244848 |
| TMEM45B | transmembrane protein 45B | -0.0242243 |
| RPS23 | ribosomal protein S23 | -0.024032 |
| HLA-A | major histocompatibility complex, class I, A | -0.0236734 |
| WDR45B | WD repeat domain 45B | -0.0234365 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0232279 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0231581 |
| TRAK1 | trafficking protein, kinesin binding 1 | -0.0229819 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0227708 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0225069 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0218954 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0218947 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0214895 |
| LASP1 | LIM and SH3 protein 1 | -0.0212079 |
| FOXQ1 | forkhead box Q1 | -0.0211744 |
| TAPBP | TAP binding protein (tapasin) | -0.0211715 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0211582 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0207222 |
| MUC13 | mucin 13, cell surface associated | -0.0205933 |
| KRT7 | keratin 7, type II | -0.0205224 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0202518 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.0201782 |
| AZIN1 | antizyme inhibitor 1 | -0.0200382 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.019994 |
| EZR | ezrin | -0.0199594 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0198894 |
| WBP2 | WW domain binding protein 2 | -0.019843 |
| UBB | ubiquitin B | -0.0194395 |
| HLA-B | major histocompatibility complex, class I, B | -0.0192739 |
| TOB1 | transducer of ERBB2, 1 | -0.0192163 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0192125 |
| ATF4 | activating transcription factor 4 | -0.0191802 |
| RLIM | ring finger protein, LIM domain interacting | -0.0189935 |
| ACTN4 | actinin, alpha 4 | -0.018967 |
