| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ralimetinib dimesylate perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ralimetinib dimesylate_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0977888 |
| RPS12 | ribosomal protein S12 | 0.0795363 |
| ASPH | aspartate beta-hydroxylase | 0.05448 |
| RPS3 | ribosomal protein S3 | 0.0456306 |
| RPS17 | ribosomal protein S17 | 0.0421768 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.041438 |
| RPL23 | ribosomal protein L23 | 0.0389587 |
| RPL37A | ribosomal protein L37a | 0.0373603 |
| ITGA6 | integrin, alpha 6 | 0.0368423 |
| DTNA | dystrobrevin, alpha | 0.0358706 |
| VIM | vimentin | 0.0334988 |
| RPL12 | ribosomal protein L12 | 0.0333286 |
| PCBP2 | poly(rC) binding protein 2 | 0.0286373 |
| ENO1 | enolase 1, (alpha) | 0.0286242 |
| MT2A | metallothionein 2A | 0.0283456 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0282096 |
| FLNA | filamin A, alpha | 0.0272621 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0254212 |
| RPS8 | ribosomal protein S8 | 0.0247121 |
| RPL9 | ribosomal protein L9 | 0.0236119 |
| RRM2 | ribonucleotide reductase M2 | 0.023437 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0227569 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0226236 |
| SET | SET nuclear proto-oncogene | 0.0219348 |
| RPL27 | ribosomal protein L27 | 0.0209721 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0208308 |
| CREB5 | cAMP responsive element binding protein 5 | 0.020077 |
| RPLP1 | ribosomal protein, large, P1 | 0.0198911 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0198402 |
| MYO6 | myosin VI | 0.0198245 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0195454 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0194878 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0189829 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0188843 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0186838 |
| PRELID2 | PRELI domain containing 2 | 0.0184997 |
| TPM3 | tropomyosin 3 | 0.0184295 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0183952 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0182617 |
| IRS2 | insulin receptor substrate 2 | 0.0180831 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0179584 |
| RPL7 | ribosomal protein L7 | 0.0177224 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0174282 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0174089 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0173267 |
| RPS7 | ribosomal protein S7 | 0.0172737 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.017188 |
| YAP1 | Yes-associated protein 1 | 0.0171872 |
| RACK1 | receptor for activated C kinase 1 | 0.0169489 |
| NUP58 | nucleoporin 58 | 0.0169395 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0168133 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0166089 |
| RPS25 | ribosomal protein S25 | 0.0165684 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0163568 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0162876 |
| SMYD3 | SET and MYND domain containing 3 | 0.0161703 |
| SEPTIN7 | septin 7 | 0.0160547 |
| NFIA | nuclear factor I/A | 0.0160326 |
| XPO1 | exportin 1 | 0.0159686 |
| RPL21 | ribosomal protein L21 | 0.015794 |
| MALT1 | MALT1 paracaspase | 0.0157164 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0156553 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.015594 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0155767 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0154727 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0153733 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.015364 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0153389 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | 0.0153154 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0152286 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0151105 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0149498 |
| PRKD1 | protein kinase D1 | 0.0149133 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0148055 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0147874 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0146479 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0146476 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.014584 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0145266 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0142464 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0137175 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0136859 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0136568 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0135899 |
| CEP152 | centrosomal protein 152kDa | 0.0135661 |
| RPLP0 | ribosomal protein, large, P0 | 0.0135482 |
| HMGA2 | high mobility group AT-hook 2 | 0.0134862 |
| MKI67 | marker of proliferation Ki-67 | 0.0133842 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0133778 |
| ZNF292 | zinc finger protein 292 | 0.0132801 |
| USP33 | ubiquitin specific peptidase 33 | 0.0132608 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0131579 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | 0.0131561 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0131321 |
| RPL26 | ribosomal protein L26 | 0.0130393 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0130324 |
| PNN | pinin, desmosome associated protein | 0.012788 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0125611 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0124854 |
| RPL31 | ribosomal protein L31 | 0.0124324 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.433523 |
| MMP12 | matrix metallopeptidase 12 | -0.201733 |
| LSAMP | limbic system-associated membrane protein | -0.163826 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.146572 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.145753 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.137744 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.114267 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.104203 |
| NTM | neurotrimin | -0.0915724 |
| ACTG1 | actin gamma 1 | -0.0879767 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0836015 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0813822 |
| PTCHD4 | patched domain containing 4 | -0.0786401 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0776536 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0735091 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.069084 |
| EFNA5 | ephrin-A5 | -0.068266 |
| AHNAK | AHNAK nucleoprotein | -0.0677144 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0672604 |
| CTSB | cathepsin B | -0.0628484 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0617466 |
| KYNU | kynureninase | -0.0603912 |
| FN1 | fibronectin 1 | -0.0588665 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0579196 |
| FOXP1 | forkhead box P1 | -0.057524 |
| MYO10 | myosin X | -0.0551036 |
| GPC6 | glypican 6 | -0.0550241 |
| HAS2 | hyaluronan synthase 2 | -0.0545703 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0539307 |
| HDAC9 | histone deacetylase 9 | -0.0537048 |
| ENKUR | enkurin, TRPC channel interacting protein | -0.0536094 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0519 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0512029 |
| PTK2 | protein tyrosine kinase 2 | -0.0490109 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0480494 |
| FRMD6 | FERM domain containing 6 | -0.047039 |
| SBF2 | SET binding factor 2 | -0.047017 |
| RUNX1 | runt-related transcription factor 1 | -0.0462311 |
| RIGI | RNA sensor RIG-I | -0.0457209 |
| CANX | calnexin | -0.0452381 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0439012 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.04384 |
| DST | dystonin | -0.0437588 |
| RAI14 | retinoic acid induced 14 | -0.0435837 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0435701 |
| VCL | vinculin | -0.0434962 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0429805 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0425101 |
| ERBIN | erbb2 interacting protein | -0.0418928 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0416281 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0416052 |
| TMSB10 | thymosin beta 10 | -0.0415437 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0412908 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0408688 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.040842 |
| H1-0 | H1.0 linker histone | -0.040565 |
| EGR1 | early growth response 1 | -0.0405387 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0404191 |
| NF1 | neurofibromin 1 | -0.0402289 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0393862 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0393194 |
| ZNF804A | zinc finger protein 804A | -0.0392353 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0389875 |
| CDH13 | cadherin 13 | -0.0382994 |
| ZNF217 | zinc finger protein 217 | -0.0372217 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0371477 |
| NETO1 | neuropilin (NRP) and tolloid (TLL)-like 1 | -0.0371047 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.036917 |
| ADAM19 | ADAM metallopeptidase domain 19 | -0.0365686 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0362954 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0359718 |
| JMJD1C | jumonji domain containing 1C | -0.0359585 |
| TXNRD1 | thioredoxin reductase 1 | -0.0356685 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0351775 |
| CUX1 | cut-like homeobox 1 | -0.0346146 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0342957 |
| FMN1 | formin 1 | -0.0335999 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0335307 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0334683 |
| MSR1 | macrophage scavenger receptor 1 | -0.0333005 |
| CDK6 | cyclin-dependent kinase 6 | -0.0332746 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0325182 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0315657 |
| NABP1 | nucleic acid binding protein 1 | -0.0310816 |
| MAP4 | microtubule-associated protein 4 | -0.0308237 |
| CFAP251 | cilia and flagella associated protein 251 | -0.0305263 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.0301368 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0301138 |
| RASAL2 | RAS protein activator like 2 | -0.0300974 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0300253 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0298881 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0298344 |
| TCF12 | transcription factor 12 | -0.0297079 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0296508 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0296165 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0295424 |
| RPL8 | ribosomal protein L8 | -0.0294725 |
| USP34 | ubiquitin specific peptidase 34 | -0.0293552 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0290571 |
| AEBP2 | AE binding protein 2 | -0.0288607 |
