| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ralimetinib dimesylate perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ralimetinib dimesylate_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.117438 |
| RPS12 | ribosomal protein S12 | 0.0755463 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0613216 |
| NEBL | nebulette | 0.0520714 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0475753 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0474249 |
| RNF43 | ring finger protein 43 | 0.0427273 |
| B2M | beta-2-microglobulin | 0.0404895 |
| EREG | epiregulin | 0.0404148 |
| RPS8 | ribosomal protein S8 | 0.0378371 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0360318 |
| PRELID2 | PRELI domain containing 2 | 0.0340185 |
| RPL37A | ribosomal protein L37a | 0.0321119 |
| RPL9 | ribosomal protein L9 | 0.0308264 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0296799 |
| FHIT | fragile histidine triad | 0.0289955 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0284672 |
| FAM13A | family with sequence similarity 13, member A | 0.027582 |
| RPS17 | ribosomal protein S17 | 0.0268816 |
| RPLP2 | ribosomal protein, large, P2 | 0.0266103 |
| RAD51B | RAD51 paralog B | 0.0264008 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0260281 |
| NEK7 | NIMA-related kinase 7 | 0.0259609 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0259223 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.025615 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0255667 |
| RPLP1 | ribosomal protein, large, P1 | 0.0254081 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0251164 |
| RPS3 | ribosomal protein S3 | 0.0241522 |
| MATR3 | matrin 3 | 0.0231678 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0229315 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0228996 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0227162 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0226448 |
| SET | SET nuclear proto-oncogene | 0.0225759 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.022463 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0224252 |
| SMYD3 | SET and MYND domain containing 3 | 0.0221779 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.021629 |
| OGA | O-GlcNAcase | 0.0214767 |
| RPL23 | ribosomal protein L23 | 0.0214596 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0214186 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0208361 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0203662 |
| PCM1 | pericentriolar material 1 | 0.0202133 |
| RPL26 | ribosomal protein L26 | 0.0199936 |
| RPS6 | ribosomal protein S6 | 0.0198177 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0198129 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.01961 |
| RABGAP1 | RAB GTPase activating protein 1 | 0.0194736 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0194103 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0193133 |
| ENO1 | enolase 1, (alpha) | 0.0192977 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.019252 |
| TPR | translocated promoter region, nuclear basket protein | 0.0190187 |
| PUM2 | pumilio RNA-binding family member 2 | 0.018859 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0188498 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0187479 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0185592 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0182709 |
| METTL15 | methyltransferase like 15 | 0.0181261 |
| RPL37 | ribosomal protein L37 | 0.0180809 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0178887 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0178294 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0178185 |
| PHF3 | PHD finger protein 3 | 0.0176565 |
| CUL3 | cullin 3 | 0.0176546 |
| PDZD8 | PDZ domain containing 8 | 0.0175072 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0171601 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0170365 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0167479 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0167166 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0166325 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0164261 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0163531 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0163211 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0162092 |
| RPS7 | ribosomal protein S7 | 0.0160387 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0160283 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0159555 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0158946 |
| CDK19 | cyclin-dependent kinase 19 | 0.0158859 |
| HYOU1 | hypoxia up-regulated 1 | 0.0157998 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0157157 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.015671 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0156235 |
| MACROD2 | MACRO domain containing 2 | 0.0155863 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0155828 |
| KIF5B | kinesin family member 5B | 0.0155665 |
| KAZN | kazrin, periplakin interacting protein | 0.0155454 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0154502 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0154179 |
| ZNF292 | zinc finger protein 292 | 0.0153934 |
| CCNC | cyclin C | 0.0153927 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0153704 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0153478 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0152108 |
| DENND4C | DENN/MADD domain containing 4C | 0.0151034 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0146901 |
| KIAA1328 | KIAA1328 | 0.0146834 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.236573 |
| NPSR1 | neuropeptide S receptor 1 | -0.213559 |
| ITGA6 | integrin, alpha 6 | -0.177451 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.170333 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.124021 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.123199 |
| ANXA2 | annexin A2 | -0.120002 |
| FAT1 | FAT atypical cadherin 1 | -0.118508 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.114251 |
| FLNB | filamin B, beta | -0.113754 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.110897 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.11071 |
| EZR | ezrin | -0.101025 |
| KRT18 | keratin 18, type I | -0.0990003 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0965231 |
| TMSB10 | thymosin beta 10 | -0.0923669 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0900176 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0899745 |
| NDRG1 | N-myc downstream regulated 1 | -0.0893549 |
| LAMA4 | laminin, alpha 4 | -0.0883438 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0820707 |
| CALB1 | calbindin 1, 28kDa | -0.0763534 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0760143 |
| LMO7 | LIM domain 7 | -0.0759567 |
| MYO1E | myosin IE | -0.0741505 |
| EMP1 | epithelial membrane protein 1 | -0.0727016 |
| ASPH | aspartate beta-hydroxylase | -0.0696206 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0678941 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0663668 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0663583 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.065844 |
| LDHA | lactate dehydrogenase A | -0.0653376 |
| MUC17 | mucin 17, cell surface associated | -0.0627233 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0605047 |
| PGK1 | phosphoglycerate kinase 1 | -0.0586577 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | -0.0577803 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0558859 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0554758 |
| ACTN4 | actinin, alpha 4 | -0.0541832 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0533183 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0513702 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0499878 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0492591 |
| RNF217 | ring finger protein 217 | -0.0488023 |
| ACTG1 | actin gamma 1 | -0.0478553 |
| KRT19 | keratin 19, type I | -0.0458864 |
| PIGR | polymeric immunoglobulin receptor | -0.0456311 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0451201 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0440118 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0439185 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0438344 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0436745 |
| POTEF | POTE ankyrin domain family, member F | -0.0434584 |
| HMGA1 | high mobility group AT-hook 1 | -0.0434559 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0433777 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.043079 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.042398 |
| FERMT1 | fermitin family member 1 | -0.0422079 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0420376 |
| DSPP | dentin sialophosphoprotein | -0.0419263 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.04148 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0413486 |
| RCOR1 | REST corepressor 1 | -0.0410897 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0410471 |
| SVIL | supervillin | -0.0402736 |
| CLOCK | clock circadian regulator | -0.0402655 |
| SLC38A2 | solute carrier family 38, member 2 | -0.040032 |
| ARHGAP6 | Rho GTPase activating protein 6 | -0.0397288 |
| SH3D19 | SH3 domain containing 19 | -0.0390952 |
| AHNAK | AHNAK nucleoprotein | -0.0387819 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0387107 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0386688 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0385443 |
| AGR2 | anterior gradient 2 | -0.0377744 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0376833 |
| GDF15 | growth differentiation factor 15 | -0.0376768 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0372837 |
| ITGB4 | integrin, beta 4 | -0.0371023 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0360574 |
| S100A6 | S100 calcium binding protein A6 | -0.0357688 |
| H1-0 | H1.0 linker histone | -0.0357123 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0353586 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0350427 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0349307 |
| UBC | ubiquitin C | -0.0349086 |
| VCL | vinculin | -0.0348682 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0346289 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0345664 |
| RIN2 | Ras and Rab interactor 2 | -0.0343846 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.034142 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0340031 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0339161 |
| PTMA | prothymosin, alpha | -0.0338639 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0331833 |
| EHBP1 | EH domain binding protein 1 | -0.0331081 |
| GPHN | gephyrin | -0.0330783 |
| MSI2 | musashi RNA-binding protein 2 | -0.0330316 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0329741 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0326662 |
| KRT8 | keratin 8, type II | -0.0323392 |
