| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ralimetinib dimesylate perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ralimetinib dimesylate_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.101009 |
| TMSB10 | thymosin beta 10 | 0.0743153 |
| ANGPTL4 | angiopoietin-like 4 | 0.0678775 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0656573 |
| GPC6 | glypican 6 | 0.0554198 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.053065 |
| MT2A | metallothionein 2A | 0.0495166 |
| RPS12 | ribosomal protein S12 | 0.0494553 |
| B2M | beta-2-microglobulin | 0.0461555 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0460254 |
| RPS17 | ribosomal protein S17 | 0.0456534 |
| PRELID2 | PRELI domain containing 2 | 0.044602 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0427081 |
| IFI44L | interferon-induced protein 44-like | 0.042547 |
| PCBP2 | poly(rC) binding protein 2 | 0.0424144 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0412101 |
| RPS19 | ribosomal protein S19 | 0.0403812 |
| ENO1 | enolase 1, (alpha) | 0.0395416 |
| RPL36 | ribosomal protein L36 | 0.0380777 |
| RPL37A | ribosomal protein L37a | 0.0375332 |
| LDHA | lactate dehydrogenase A | 0.0355682 |
| RPS3 | ribosomal protein S3 | 0.0343778 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.033519 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0334639 |
| FTL | ferritin, light polypeptide | 0.0324964 |
| NAV2 | neuron navigator 2 | 0.0321805 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0319793 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0312517 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.031188 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0308879 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0305757 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.03051 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0302554 |
| FAM13A | family with sequence similarity 13, member A | 0.0293001 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0292141 |
| EHBP1 | EH domain binding protein 1 | 0.0281908 |
| AADAC | arylacetamide deacetylase | 0.0281053 |
| USP34 | ubiquitin specific peptidase 34 | 0.0279948 |
| RNF213 | ring finger protein 213 | 0.0278426 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0273888 |
| RPLP2 | ribosomal protein, large, P2 | 0.0271258 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0271126 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0261557 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0260937 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0259975 |
| SP100 | SP100 nuclear antigen | 0.0259908 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0259478 |
| EXOC4 | exocyst complex component 4 | 0.024572 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0242302 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0239191 |
| C1R | complement component 1, r subcomponent | 0.0233348 |
| BPTF | bromodomain PHD finger transcription factor | 0.0219307 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0219256 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0217846 |
| MX2 | MX dynamin-like GTPase 2 | 0.0216395 |
| PLIN2 | perilipin 2 | 0.021593 |
| DOCK10 | dedicator of cytokinesis 10 | 0.0210477 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0205379 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.020514 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0204946 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0201752 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0201674 |
| RPS27 | ribosomal protein S27 | 0.0197653 |
| RAB13 | RAB13, member RAS oncogene family | 0.0195249 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.019523 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.019223 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0190742 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0190635 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0189717 |
| RPL35A | ribosomal protein L35a | 0.0189247 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0189026 |
| RPS8 | ribosomal protein S8 | 0.0188932 |
| CDK19 | cyclin-dependent kinase 19 | 0.0188033 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0187947 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0187768 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0186468 |
| RPL18 | ribosomal protein L18 | 0.0184819 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0184284 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0182562 |
| VEGFA | vascular endothelial growth factor A | 0.0181073 |
| MECOM | MDS1 and EVI1 complex locus | 0.017984 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0179304 |
| MX1 | MX dynamin-like GTPase 1 | 0.0177511 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0176913 |
| S100A6 | S100 calcium binding protein A6 | 0.0176791 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.017546 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0175224 |
| CALD1 | caldesmon 1 | 0.0175014 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0173966 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0170271 |
| SEPTIN2 | septin 2 | 0.0170037 |
| MYADM | myeloid-associated differentiation marker | 0.0169517 |
| DPYD | dihydropyrimidine dehydrogenase | 0.016876 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0168651 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0168421 |
| RPL31 | ribosomal protein L31 | 0.0168252 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0166696 |
| SMYD3 | SET and MYND domain containing 3 | 0.0166534 |
| RUNX1 | runt-related transcription factor 1 | 0.0166425 |
| CTSC | cathepsin C | 0.0166026 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.334244 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.169156 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.139194 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.114637 |
| CD44 | CD44 molecule (Indian blood group) | -0.0986493 |
| GLCCI1 | glucocorticoid induced 1 | -0.0915225 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0867987 |
| GOLGA4 | golgin A4 | -0.0758594 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0740765 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0667977 |
| RBM39 | RNA binding motif protein 39 | -0.0650048 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0615768 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0593502 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0587612 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0515718 |
| FN1 | fibronectin 1 | -0.0510382 |
| NRP1 | neuropilin 1 | -0.049668 |
| CANX | calnexin | -0.048829 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0486284 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0483819 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0481961 |
| JMJD1C | jumonji domain containing 1C | -0.046907 |
| LOX | lysyl oxidase | -0.0456512 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0447256 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0433599 |
| SPAG9 | sperm associated antigen 9 | -0.0423492 |
| UBC | ubiquitin C | -0.0418377 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0414432 |
| HMGA2 | high mobility group AT-hook 2 | -0.0412895 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0412559 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0409793 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0398247 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0395002 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0387325 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0382577 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0376167 |
| NDRG1 | N-myc downstream regulated 1 | -0.0364018 |
| OSMR | oncostatin M receptor | -0.0359285 |
| CALU | calumenin | -0.035516 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0352519 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0351903 |
| TMEM263 | transmembrane protein 263 | -0.0350906 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.034831 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0347291 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.034613 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0346109 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0345037 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0343849 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0343718 |
| CLTC | clathrin, heavy chain (Hc) | -0.0342825 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0341164 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0340046 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0338334 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0336744 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0325812 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0322065 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0321438 |
| USP3 | ubiquitin specific peptidase 3 | -0.0316443 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0315652 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0313558 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0303647 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0302592 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0302421 |
| SETD5 | SET domain containing 5 | -0.0301574 |
| H1-0 | H1.0 linker histone | -0.0301246 |
| AHNAK | AHNAK nucleoprotein | -0.0300925 |
| ARF4 | ADP-ribosylation factor 4 | -0.0299393 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0297782 |
| GLG1 | golgi glycoprotein 1 | -0.029776 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0290625 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0289721 |
| WLS | wntless Wnt ligand secretion mediator | -0.0289476 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0283165 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0279474 |
| YBX1 | Y box binding protein 1 | -0.0275889 |
| SRP54 | signal recognition particle 54kDa | -0.0274965 |
| FBXO11 | F-box protein 11 | -0.0274705 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0273958 |
| VCL | vinculin | -0.0273329 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0269558 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0268807 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0262498 |
| IER3 | immediate early response 3 | -0.0255385 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0251424 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0251321 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0250168 |
| FOXO3 | forkhead box O3 | -0.0250145 |
| COPA | coatomer protein complex, subunit alpha | -0.0249706 |
| ARF1 | ADP-ribosylation factor 1 | -0.0248444 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.024549 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0245044 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0244711 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0243346 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0241914 |
| PARD3 | par-3 family cell polarity regulator | -0.0241718 |
| SMAD3 | SMAD family member 3 | -0.024161 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0241396 |
| ECE1 | endothelin converting enzyme 1 | -0.0240756 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0240648 |
| ATXN1 | ataxin 1 | -0.0239126 |
