| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ralimetinib dimesylate perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ralimetinib dimesylate_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.118117 |
| EFNA5 | ephrin-A5 | 0.117137 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0871486 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0867611 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0766108 |
| ASPH | aspartate beta-hydroxylase | 0.0744078 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0671409 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0665879 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0656059 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0643543 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0641692 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0573236 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0563691 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0539439 |
| VIM | vimentin | 0.0535797 |
| TXNRD1 | thioredoxin reductase 1 | 0.0524362 |
| OGA | O-GlcNAcase | 0.0511473 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0502214 |
| RPS12 | ribosomal protein S12 | 0.0500071 |
| NEK7 | NIMA-related kinase 7 | 0.0497668 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0483087 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0472829 |
| CD109 | CD109 molecule | 0.0466697 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0453764 |
| RTN4 | reticulon 4 | 0.0442551 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0438547 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0430312 |
| GDA | guanine deaminase | 0.0424722 |
| SMYD3 | SET and MYND domain containing 3 | 0.0418142 |
| FAM13A | family with sequence similarity 13, member A | 0.0417097 |
| WDR43 | WD repeat domain 43 | 0.0412562 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0404653 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0400729 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0398244 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0395152 |
| GRAMD1B | GRAM domain containing 1B | 0.0392567 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0392123 |
| PTGR1 | prostaglandin reductase 1 | 0.0387915 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0384921 |
| PTEN | phosphatase and tensin homolog | 0.0384507 |
| ENAH | enabled homolog (Drosophila) | 0.0353674 |
| SPAG9 | sperm associated antigen 9 | 0.0353038 |
| NBAS | neuroblastoma amplified sequence | 0.0350791 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0345367 |
| NCKAP1 | NCK-associated protein 1 | 0.033191 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0331006 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0327295 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0324018 |
| TNPO1 | transportin 1 | 0.0321114 |
| LAMB1 | laminin, beta 1 | 0.0318973 |
| RPS3 | ribosomal protein S3 | 0.0318835 |
| PTMA | prothymosin, alpha | 0.0318351 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0317139 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0313036 |
| MYOF | myoferlin | 0.0311341 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0310084 |
| USP3 | ubiquitin specific peptidase 3 | 0.0308542 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0307953 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0307638 |
| MATR3 | matrin 3 | 0.0302668 |
| ZNF292 | zinc finger protein 292 | 0.0301485 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0299662 |
| CTSC | cathepsin C | 0.0288657 |
| FLNB | filamin B, beta | 0.0286447 |
| RNF145 | ring finger protein 145 | 0.0285243 |
| COL5A2 | collagen, type V, alpha 2 | 0.0284275 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0281792 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0281323 |
| SRPK2 | SRSF protein kinase 2 | 0.0276553 |
| RAI1 | retinoic acid induced 1 | 0.0273836 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0271273 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0270309 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0266667 |
| PTK2 | protein tyrosine kinase 2 | 0.0264807 |
| ATP13A3 | ATPase type 13A3 | 0.0264667 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0261308 |
| ANXA1 | annexin A1 | 0.0261021 |
| RBM25 | RNA binding motif protein 25 | 0.0253013 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0252076 |
| ANXA2 | annexin A2 | 0.0251704 |
| TCERG1 | transcription elongation regulator 1 | 0.0251077 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0250907 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0250178 |
| NRCAM | neuronal cell adhesion molecule | 0.0248836 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.024881 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0247306 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0244289 |
| SET | SET nuclear proto-oncogene | 0.0242664 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0240155 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0238338 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0238182 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0237123 |
| RBM39 | RNA binding motif protein 39 | 0.0235606 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0233807 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0232781 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0232683 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0232416 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0230442 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.022924 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0228884 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.443832 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.234611 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.121173 |
| FN1 | fibronectin 1 | -0.107913 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0862583 |
| ACTG1 | actin gamma 1 | -0.0701911 |
| VCL | vinculin | -0.0693697 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0669389 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0654181 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0620496 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0588352 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0528174 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0490548 |
| DST | dystonin | -0.0476571 |
| UBC | ubiquitin C | -0.0461084 |
| RPS23 | ribosomal protein S23 | -0.0441951 |
| INTS6 | integrator complex subunit 6 | -0.0439051 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0425263 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0418373 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0417695 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0405227 |
| MT2A | metallothionein 2A | -0.0401007 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0397725 |
| CANX | calnexin | -0.039679 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0395979 |
| FTL | ferritin, light polypeptide | -0.0375524 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | -0.0375102 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0371961 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.036869 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0366521 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0361661 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0360828 |
| CDH13 | cadherin 13 | -0.0350437 |
| SQSTM1 | sequestosome 1 | -0.0319422 |
| RPLP1 | ribosomal protein, large, P1 | -0.0310394 |
| AUTS2 | autism susceptibility candidate 2 | -0.0301995 |
| S100A10 | S100 calcium binding protein A10 | -0.0300741 |
| LSAMP | limbic system-associated membrane protein | -0.0274113 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0271861 |
| RPL34 | ribosomal protein L34 | -0.0271279 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.027105 |
| POTEF | POTE ankyrin domain family, member F | -0.0270815 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.025265 |
| EGR1 | early growth response 1 | -0.0243912 |
| SMAD2 | SMAD family member 2 | -0.0239753 |
| RPL38 | ribosomal protein L38 | -0.0239744 |
| GLRX | glutaredoxin (thioltransferase) | -0.0239609 |
| NDRG1 | N-myc downstream regulated 1 | -0.0238592 |
| RPS15 | ribosomal protein S15 | -0.0233335 |
| RPLP0 | ribosomal protein, large, P0 | -0.0232448 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0231757 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0230688 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0227545 |
| ARF1 | ADP-ribosylation factor 1 | -0.0225085 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0222954 |
| RPS13 | ribosomal protein S13 | -0.0218448 |
| RPL39 | ribosomal protein L39 | -0.0218021 |
| RPS24 | ribosomal protein S24 | -0.0210826 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0205929 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0205897 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0202192 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase | -0.0193181 |
| RPL8 | ribosomal protein L8 | -0.0192587 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0192378 |
| IER3 | immediate early response 3 | -0.0189263 |
| RPS21 | ribosomal protein S21 | -0.0187771 |
| CREM | cAMP responsive element modulator | -0.0187499 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0186469 |
| LAMB4 | laminin, beta 4 | -0.0176474 |
| RPL31 | ribosomal protein L31 | -0.0175843 |
| RPS27A | ribosomal protein S27a | -0.0175022 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0174641 |
| RPS29 | ribosomal protein S29 | -0.0174427 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.017313 |
| CUX1 | cut-like homeobox 1 | -0.0172885 |
| STC1 | stanniocalcin 1 | -0.0172546 |
| RPS11 | ribosomal protein S11 | -0.0171894 |
| RGS2 | regulator of G-protein signaling 2 | -0.0171335 |
| PCDH9 | protocadherin 9 | -0.0171055 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.016902 |
| TBCA | tubulin folding cofactor A | -0.0166463 |
| MFSD12 | major facilitator superfamily domain containing 12 | -0.0165831 |
| XYLT1 | xylosyltransferase I | -0.0164479 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0163384 |
| AEBP2 | AE binding protein 2 | -0.0161886 |
| NRXN3 | neurexin 3 | -0.0160727 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0157644 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0156152 |
| MT1X | metallothionein 1X | -0.0155032 |
| RPL28 | ribosomal protein L28 | -0.0154661 |
| RPS20 | ribosomal protein S20 | -0.0152878 |
| SRGN | serglycin | -0.0150716 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | -0.0150134 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.014984 |
| PKM | pyruvate kinase, muscle | -0.0149695 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0148912 |
| CADM2 | cell adhesion molecule 2 | -0.0146956 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | -0.0146837 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.014644 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0146151 |
