| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ralimetinib dimesylate perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ralimetinib dimesylate_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.102482 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0744337 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0708102 |
| MKI67 | marker of proliferation Ki-67 | 0.0648057 |
| RPL23 | ribosomal protein L23 | 0.0557586 |
| NAV2 | neuron navigator 2 | 0.0533162 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0515186 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0511376 |
| HMGB2 | high mobility group box 2 | 0.049524 |
| RPS12 | ribosomal protein S12 | 0.0472345 |
| RUNX1 | runt-related transcription factor 1 | 0.046719 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0461209 |
| RPS8 | ribosomal protein S8 | 0.0455666 |
| RPL37A | ribosomal protein L37a | 0.0448825 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0443637 |
| OGA | O-GlcNAcase | 0.0440847 |
| SMYD3 | SET and MYND domain containing 3 | 0.0437693 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0432593 |
| RPS6 | ribosomal protein S6 | 0.0424789 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0410549 |
| RPLP1 | ribosomal protein, large, P1 | 0.0406691 |
| ETV6 | ets variant 6 | 0.0406191 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0400346 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0376365 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0367764 |
| ZNF292 | zinc finger protein 292 | 0.0364885 |
| DIAPH3 | diaphanous-related formin 3 | 0.0360346 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0359393 |
| RPS17 | ribosomal protein S17 | 0.0357928 |
| AFAP1 | actin filament associated protein 1 | 0.0357207 |
| MATR3 | matrin 3 | 0.0355993 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0353172 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0351064 |
| RYK | receptor-like tyrosine kinase | 0.0344638 |
| DST | dystonin | 0.033644 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0336119 |
| PRELID2 | PRELI domain containing 2 | 0.0329192 |
| AFDN | afadin, adherens junction formation factor | 0.0318979 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.031207 |
| RPS3 | ribosomal protein S3 | 0.0311827 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0311077 |
| CENPF | centromere protein F, 350/400kDa | 0.0307549 |
| RPL9 | ribosomal protein L9 | 0.0305883 |
| KIAA1217 | KIAA1217 | 0.0305141 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0304812 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0298861 |
| RPL26 | ribosomal protein L26 | 0.0297851 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0292207 |
| RASA2 | RAS p21 protein activator 2 | 0.0291148 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0290556 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0282932 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0279262 |
| RPS27A | ribosomal protein S27a | 0.027671 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0273611 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0272391 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.027197 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0270766 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0270296 |
| FRMD5 | FERM domain containing 5 | 0.0268317 |
| SMAD3 | SMAD family member 3 | 0.0267791 |
| KLC1 | kinesin light chain 1 | 0.0267538 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0264489 |
| IRS2 | insulin receptor substrate 2 | 0.0258376 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0258118 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0257435 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0256304 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0256246 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0254839 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0253105 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.025307 |
| STK24 | serine/threonine kinase 24 | 0.0252383 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0251403 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0250424 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0250372 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0249459 |
| XPO1 | exportin 1 | 0.0249424 |
| LRRC1 | leucine rich repeat containing 1 | 0.0248102 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0245237 |
| UBQLN1 | ubiquilin 1 | 0.024373 |
| PTK2 | protein tyrosine kinase 2 | 0.0239422 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0236622 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0236253 |
| NFIB | nuclear factor I/B | 0.0234613 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0231234 |
| TSC22D2 | TSC22 domain family, member 2 | 0.023045 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0230168 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0228404 |
| WWOX | WW domain containing oxidoreductase | 0.0228016 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0225969 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0224414 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0224353 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0223349 |
| RPL37 | ribosomal protein L37 | 0.0223201 |
| RNF149 | ring finger protein 149 | 0.0222988 |
| GPHN | gephyrin | 0.0222469 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0221631 |
| RPL27 | ribosomal protein L27 | 0.0220607 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0214914 |
| RLF | rearranged L-myc fusion | 0.0214881 |
| ATP13A3 | ATPase type 13A3 | 0.0214771 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.241274 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.216033 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.179672 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.162105 |
| EMP1 | epithelial membrane protein 1 | -0.136374 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.12379 |
| EZR | ezrin | -0.114804 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.108109 |
| NDRG1 | N-myc downstream regulated 1 | -0.10285 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.101562 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.100543 |
| HMGA1 | high mobility group AT-hook 1 | -0.0879197 |
| ANXA2 | annexin A2 | -0.0839354 |
| FN1 | fibronectin 1 | -0.0806684 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0740602 |
| KRT19 | keratin 19, type I | -0.0736103 |
| LDHA | lactate dehydrogenase A | -0.0722246 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0700413 |
| UBC | ubiquitin C | -0.0685401 |
| EGR1 | early growth response 1 | -0.0681663 |
| POTEF | POTE ankyrin domain family, member F | -0.0672719 |
| LAMA4 | laminin, alpha 4 | -0.0665772 |
| TMSB4X | thymosin beta 4, X-linked | -0.0618965 |
| CD2AP | CD2-associated protein | -0.0614486 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.061442 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | -0.0598116 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0594431 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0584173 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0576157 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0559782 |
| GOLGB1 | golgin B1 | -0.0554618 |
| ARF4 | ADP-ribosylation factor 4 | -0.0523149 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0521121 |
| DSG2 | desmoglein 2 | -0.0517617 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0503957 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0499674 |
| LAMB3 | laminin, beta 3 | -0.0490492 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.048742 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.047817 |
| INTS6 | integrator complex subunit 6 | -0.0477763 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0472345 |
| MUC4 | mucin 4, cell surface associated | -0.0470895 |
| MYO1E | myosin IE | -0.0469456 |
| RASAL2 | RAS protein activator like 2 | -0.0465707 |
| TPI1 | triosephosphate isomerase 1 | -0.04635 |
| ERBIN | erbb2 interacting protein | -0.0455331 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0448281 |
| CLDN4 | claudin 4 | -0.0447384 |
| JMJD1C | jumonji domain containing 1C | -0.0441935 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0438622 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0434242 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0427011 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.042404 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0422402 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0417844 |
| TJP1 | tight junction protein 1 | -0.0417771 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.0407665 |
| LIPH | lipase, member H | -0.0406486 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0404829 |
| PLK2 | polo-like kinase 2 | -0.0402325 |
| DAPK1 | death-associated protein kinase 1 | -0.0400247 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0386897 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0385636 |
| HLA-B | major histocompatibility complex, class I, B | -0.0384811 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.038473 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0381555 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0381516 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0375763 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0370915 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0368091 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.0366981 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0362807 |
| KRT7 | keratin 7, type II | -0.0358993 |
| ANXA1 | annexin A1 | -0.0357116 |
| ATF3 | activating transcription factor 3 | -0.0351526 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0347352 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.0345415 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0341574 |
| PLAU | plasminogen activator, urokinase | -0.0341192 |
| HLA-A | major histocompatibility complex, class I, A | -0.0340059 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0340001 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0338515 |
| C3 | complement component 3 | -0.0335777 |
| VMP1 | vacuole membrane protein 1 | -0.0335566 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0333061 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0331463 |
| CANX | calnexin | -0.0327014 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0324221 |
| CCNL1 | cyclin L1 | -0.0322937 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.032216 |
| S100A10 | S100 calcium binding protein A10 | -0.0320628 |
| TMSB10 | thymosin beta 10 | -0.0319992 |
| OXSR1 | oxidative stress responsive 1 | -0.0319655 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0319527 |
| RIOK3 | RIO kinase 3 | -0.0318614 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0318439 |
| BRD2 | bromodomain containing 2 | -0.0317678 |
| RAP2B | RAP2B, member of RAS oncogene family | -0.0317388 |
| AREG | amphiregulin | -0.0308984 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0300377 |
