| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ralimetinib dimesylate perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ralimetinib dimesylate_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0503992 |
| ASPH | aspartate beta-hydroxylase | 0.0482659 |
| FAM20C | family with sequence similarity 20, member C | 0.047811 |
| NAV2 | neuron navigator 2 | 0.0451746 |
| YEATS2 | YEATS domain containing 2 | 0.0446394 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0427956 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0425387 |
| ZNF292 | zinc finger protein 292 | 0.0423615 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0420786 |
| FMNL2 | formin-like 2 | 0.0411743 |
| AFAP1 | actin filament associated protein 1 | 0.0409726 |
| NCAM1 | neural cell adhesion molecule 1 | 0.0404659 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0398139 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0386785 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0384832 |
| OGA | O-GlcNAcase | 0.0383514 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0374043 |
| ENO1 | enolase 1, (alpha) | 0.0368036 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0364896 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0362038 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0359993 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.035716 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0347562 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0345896 |
| PTK2 | protein tyrosine kinase 2 | 0.0339085 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0332188 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0332116 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0331741 |
| MKI67 | marker of proliferation Ki-67 | 0.0329108 |
| AHNAK | AHNAK nucleoprotein | 0.0327751 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0325752 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0323797 |
| ATP13A3 | ATPase type 13A3 | 0.0323582 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0320608 |
| SMYD3 | SET and MYND domain containing 3 | 0.0318643 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.031525 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0314449 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0312838 |
| MTSS1 | metastasis suppressor 1 | 0.031228 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0307687 |
| APP | amyloid beta (A4) precursor protein | 0.0306229 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0304938 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0303206 |
| MYO9A | myosin IXA | 0.0302884 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.0302002 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0299062 |
| ITGB5 | integrin, beta 5 | 0.0291083 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.028736 |
| XPO1 | exportin 1 | 0.0287351 |
| FAM13A | family with sequence similarity 13, member A | 0.0287204 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0284865 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0283952 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0283222 |
| CDK19 | cyclin-dependent kinase 19 | 0.0277594 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0277037 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0273676 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0270279 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0265834 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0265444 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0264431 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.026311 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0262942 |
| TPM1 | tropomyosin 1 (alpha) | 0.0262775 |
| NF1 | neurofibromin 1 | 0.0262375 |
| ATRN | attractin | 0.0258176 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0255027 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0254275 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0252097 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0248452 |
| CHD6 | chromodomain helicase DNA binding protein 6 | 0.0244532 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0239799 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0238282 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.023644 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0236406 |
| CAVIN1 | caveolae associated protein 1 | 0.0236119 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0233232 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0233109 |
| TOX2 | TOX high mobility group box family member 2 | 0.0232246 |
| SUCO | SUN domain containing ossification factor | 0.0232217 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0231134 |
| DNAAF9 | dynein axonemal assembly factor 9 | 0.0229895 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0229193 |
| NEK7 | NIMA-related kinase 7 | 0.0228375 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0227422 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0224093 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0224049 |
| HMGB2 | high mobility group box 2 | 0.02232 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.022243 |
| TMEM39A | transmembrane protein 39A | 0.0219781 |
| SLMAP | sarcolemma associated protein | 0.0219141 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0218829 |
| NKTR | natural killer cell triggering receptor | 0.0218566 |
| CALD1 | caldesmon 1 | 0.0218264 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0218184 |
| RNF216 | ring finger protein 216 | 0.021796 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0217151 |
| ZNF638 | zinc finger protein 638 | 0.0215826 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0215819 |
| NBAS | neuroblastoma amplified sequence | 0.0215718 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0215495 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.410381 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.15631 |
| NDRG1 | N-myc downstream regulated 1 | -0.14521 |
| FN1 | fibronectin 1 | -0.129339 |
| POTEF | POTE ankyrin domain family, member F | -0.116591 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.111681 |
| EGR1 | early growth response 1 | -0.0996289 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0941341 |
| FTL | ferritin, light polypeptide | -0.0842666 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0814799 |
| COL1A2 | collagen, type I, alpha 2 | -0.0808889 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0773674 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0769001 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0753032 |
| VIM | vimentin | -0.0700295 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0697127 |
| CLIC4 | chloride intracellular channel 4 | -0.0660312 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0653171 |
| STC1 | stanniocalcin 1 | -0.061945 |
| UBC | ubiquitin C | -0.0606677 |
| MT2A | metallothionein 2A | -0.0586056 |
| COL1A1 | collagen, type I, alpha 1 | -0.0574758 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0568802 |
| CDH13 | cadherin 13 | -0.0560736 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0559675 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0541507 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0532161 |
| NAV1 | neuron navigator 1 | -0.0503204 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0467737 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0461736 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0460285 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0443414 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0438704 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0431947 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0429637 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0425923 |
| SHISA5 | shisa family member 5 | -0.0419847 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0415972 |
| ARF4 | ADP-ribosylation factor 4 | -0.0415763 |
| ADM | adrenomedullin | -0.0406484 |
| PFN1 | profilin 1 | -0.040553 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0403274 |
| FNDC3B | fibronectin type III domain containing 3B | -0.039893 |
| IER3 | immediate early response 3 | -0.0398392 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0395939 |
| INHBA | inhibin, beta A | -0.0394829 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0390843 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0384228 |
| B2M | beta-2-microglobulin | -0.0375127 |
| PKM | pyruvate kinase, muscle | -0.0370146 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0369884 |
| LOXL2 | lysyl oxidase-like 2 | -0.0369757 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0364673 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0356836 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.03411 |
| VEGFA | vascular endothelial growth factor A | -0.03379 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0333993 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0331009 |
| NABP1 | nucleic acid binding protein 1 | -0.0328034 |
| S100A10 | S100 calcium binding protein A10 | -0.0320885 |
| LPCAT2 | lysophosphatidylcholine acyltransferase 2 | -0.0318665 |
| YBX1 | Y box binding protein 1 | -0.031529 |
| VCL | vinculin | -0.0308807 |
| MSN | moesin | -0.0304591 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0301468 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.029928 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0296681 |
| ACTG1 | actin gamma 1 | -0.0294811 |
| RPLP1 | ribosomal protein, large, P1 | -0.0293335 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0292243 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0291723 |
| IL1B | interleukin 1, beta | -0.0288647 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0285644 |
| INTS6 | integrator complex subunit 6 | -0.0279634 |
| TGFB1 | transforming growth factor, beta 1 | -0.027933 |
| CCNL1 | cyclin L1 | -0.0278407 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0278148 |
| FBXO11 | F-box protein 11 | -0.0275508 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0272238 |
| MAP1B | microtubule-associated protein 1B | -0.0268827 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0268098 |
| FOSL1 | FOS-like antigen 1 | -0.0265885 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0259083 |
| RTN4 | reticulon 4 | -0.0258843 |
| TAPBP | TAP binding protein (tapasin) | -0.0258796 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0255628 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0251987 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0251879 |
| MAGT1 | magnesium transporter 1 | -0.0251301 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0248326 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0246883 |
| MMP12 | matrix metallopeptidase 12 | -0.0243927 |
| EHD2 | EH-domain containing 2 | -0.0243816 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0243128 |
| SERF2 | small EDRK-rich factor 2 | -0.0240062 |
| WASF2 | WAS protein family, member 2 | -0.0239562 |
| LOX | lysyl oxidase | -0.023877 |
| RYBP | RING1 and YY1 binding protein | -0.0237607 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0235997 |
| S100A6 | S100 calcium binding protein A6 | -0.0234643 |
