| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ralimetinib dimesylate perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ralimetinib dimesylate_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0838198 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0596678 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0360802 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0299116 |
| DIAPH3 | diaphanous-related formin 3 | 0.0292648 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0287966 |
| HDAC9 | histone deacetylase 9 | 0.0282676 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0250736 |
| PYGB | phosphorylase, glycogen; brain | 0.0245029 |
| GLI3 | GLI family zinc finger 3 | 0.0239799 |
| PDGFC | platelet derived growth factor C | 0.0237527 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0231887 |
| EFNA5 | ephrin-A5 | 0.0225785 |
| ZNF608 | zinc finger protein 608 | 0.0221842 |
| LONRF2 | LON peptidase N-terminal domain and ring finger 2 | 0.0213791 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0205654 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.019766 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0197173 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0194685 |
| PLCE1 | phospholipase C, epsilon 1 | 0.0190961 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0180648 |
| PDE10A | phosphodiesterase 10A | 0.0179567 |
| ANKRD36B | ankyrin repeat domain 36B | 0.0178569 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0174701 |
| DAPK3 | death-associated protein kinase 3 | 0.0173871 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0172159 |
| PRELID2 | PRELI domain containing 2 | 0.0171534 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0169648 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.016924 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0164949 |
| GSE1 | Gse1 coiled-coil protein | 0.0162945 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.016271 |
| PPM1L | protein phosphatase, Mg2+/Mn2+ dependent, 1L | 0.0157087 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta | 0.0152961 |
| CD47 | CD47 molecule | 0.0146088 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0142225 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0140731 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0132417 |
| MKI67 | marker of proliferation Ki-67 | 0.0132415 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0129124 |
| LOXL3 | lysyl oxidase-like 3 | 0.0128604 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0128213 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0128095 |
| ITGA6 | integrin, alpha 6 | 0.0127181 |
| FNIP1 | folliculin interacting protein 1 | 0.0125945 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0123648 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | 0.012306 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0122997 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.012186 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0121784 |
| TJP1 | tight junction protein 1 | 0.01205 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0118867 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0118744 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0118535 |
| ZNF438 | zinc finger protein 438 | 0.0117999 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.011799 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0115644 |
| NAV2 | neuron navigator 2 | 0.0114308 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0113502 |
| SEPTIN9 | septin 9 | 0.0112847 |
| CEP250 | centrosomal protein 250kDa | 0.0111484 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0110128 |
| MCU | mitochondrial calcium uniporter | 0.010889 |
| RYK | receptor-like tyrosine kinase | 0.010696 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 0.010675 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0105986 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0104911 |
| EBNA1BP2 | EBNA1 binding protein 2 | 0.010418 |
| C2ORF92 | chromosome 2 open reading frame 92 | 0.0103858 |
| RBM26 | RNA binding motif protein 26 | 0.0102547 |
| ANXA3 | annexin A3 | 0.0101485 |
| RPL21 | ribosomal protein L21 | 0.0101287 |
| ZNF462 | zinc finger protein 462 | 0.0101282 |
| DST | dystonin | 0.0100666 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0100045 |
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) | 0.00999501 |
| PDS5B | PDS5 cohesin associated factor B | 0.00993908 |
| CENPF | centromere protein F, 350/400kDa | 0.00987511 |
| FMN1 | formin 1 | 0.00984636 |
| ASPH | aspartate beta-hydroxylase | 0.00976058 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.00969155 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.00942295 |
| TMEM14B | transmembrane protein 14B | 0.00938032 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.00935574 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.00932434 |
| DOCK5 | dedicator of cytokinesis 5 | 0.00930617 |
| CUX1 | cut-like homeobox 1 | 0.0092296 |
| MAPK14 | mitogen-activated protein kinase 14 | 0.00921579 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | 0.00906621 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | 0.009016 |
| UTRN | utrophin | 0.00901057 |
| ARGLU1 | arginine and glutamate rich 1 | 0.00893999 |
| MMS22L | MMS22-like, DNA repair protein | 0.00889126 |
| PNN | pinin, desmosome associated protein | 0.0086744 |
| CCNY | cyclin Y | 0.00864089 |
| MSH2 | mutS homolog 2 | 0.00860486 |
| TPM4 | tropomyosin 4 | 0.00852284 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.00848297 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.00847087 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.00844384 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.473445 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.231907 |
| PTMA | prothymosin, alpha | -0.174456 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.159462 |
| TMSB4X | thymosin beta 4, X-linked | -0.119928 |
| ACTG1 | actin gamma 1 | -0.109195 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.105195 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0902559 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0866174 |
| PKM | pyruvate kinase, muscle | -0.0819841 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0764816 |
| S100A6 | S100 calcium binding protein A6 | -0.0721289 |
| AHNAK | AHNAK nucleoprotein | -0.0704106 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0701471 |
| RPS6 | ribosomal protein S6 | -0.0551293 |
| LDHA | lactate dehydrogenase A | -0.0542335 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0541482 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.053093 |
| PGK1 | phosphoglycerate kinase 1 | -0.052006 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0515989 |
| GOLGA4 | golgin A4 | -0.0515692 |
| RPL35A | ribosomal protein L35a | -0.0495573 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0492007 |
| RBM39 | RNA binding motif protein 39 | -0.0487629 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0476351 |
| RPS19 | ribosomal protein S19 | -0.0454729 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0449863 |
| RHOA | ras homolog family member A | -0.0442338 |
| QKI | QKI, KH domain containing, RNA binding | -0.0439306 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0431411 |
| RPL34 | ribosomal protein L34 | -0.0420895 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.04108 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0395739 |
| SQSTM1 | sequestosome 1 | -0.0393146 |
| HDLBP | high density lipoprotein binding protein | -0.0393024 |
| B2M | beta-2-microglobulin | -0.0387072 |
| RPL11 | ribosomal protein L11 | -0.0384989 |
| RPLP0 | ribosomal protein, large, P0 | -0.0367158 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.036111 |
| RPS23 | ribosomal protein S23 | -0.0355277 |
| UBC | ubiquitin C | -0.0349775 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0338615 |
| FBXO11 | F-box protein 11 | -0.0334074 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0329878 |
| GNAS | GNAS complex locus | -0.0327941 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0327303 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0326195 |
| PFN1 | profilin 1 | -0.0326087 |
| RPS8 | ribosomal protein S8 | -0.0321684 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0321318 |
| RPL12 | ribosomal protein L12 | -0.0315183 |
| S100A10 | S100 calcium binding protein A10 | -0.0312788 |
| RPLP1 | ribosomal protein, large, P1 | -0.0312138 |
| VCL | vinculin | -0.0311668 |
| EZR | ezrin | -0.0310365 |
| RPL32 | ribosomal protein L32 | -0.0308855 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0293892 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0293378 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0291895 |
| RPL19 | ribosomal protein L19 | -0.0289445 |
| CANX | calnexin | -0.0275533 |
| RPS21 | ribosomal protein S21 | -0.0275085 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0274586 |
| RPS13 | ribosomal protein S13 | -0.0272041 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.0270437 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0269885 |
| PRDX2 | peroxiredoxin 2 | -0.0266712 |
| ZNF292 | zinc finger protein 292 | -0.0263658 |
| RLF | rearranged L-myc fusion | -0.0261383 |
| POTEF | POTE ankyrin domain family, member F | -0.0260386 |
| CALR | calreticulin | -0.0260229 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0256341 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0255727 |
| RRBP1 | ribosome binding protein 1 | -0.0252587 |
| ZNF217 | zinc finger protein 217 | -0.02525 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0247847 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0247838 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0246967 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0245108 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0243928 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0243771 |
| CCNI | cyclin I | -0.0241778 |
| SMNDC1 | survival motor neuron domain containing 1 | -0.0241023 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0240814 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0239667 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.023834 |
| RPS27A | ribosomal protein S27a | -0.0237817 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -0.0235847 |
| HLA-B | major histocompatibility complex, class I, B | -0.023548 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0235414 |
| RPS24 | ribosomal protein S24 | -0.0234217 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0233761 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0232535 |
| FUS | FUS RNA binding protein | -0.0231198 |
| TXNRD1 | thioredoxin reductase 1 | -0.0231155 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0226994 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0226897 |
| CDC73 | cell division cycle 73 | -0.0226453 |
| RPL8 | ribosomal protein L8 | -0.0223492 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0221579 |
