| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ralimetinib dimesylate perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ralimetinib dimesylate_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.105982 |
| B2M | beta-2-microglobulin | 0.0966057 |
| FMNL2 | formin-like 2 | 0.0726137 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0707005 |
| SDC4 | syndecan 4 | 0.0705113 |
| CD44 | CD44 molecule (Indian blood group) | 0.0687356 |
| ANXA2 | annexin A2 | 0.0620862 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0578385 |
| CADM1 | cell adhesion molecule 1 | 0.0554476 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0539512 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0509116 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0497264 |
| SPAG9 | sperm associated antigen 9 | 0.045611 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0454935 |
| RTN4 | reticulon 4 | 0.0452717 |
| HIP1 | huntingtin interacting protein 1 | 0.0451678 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0451377 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0438717 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0436079 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0432997 |
| NAV2 | neuron navigator 2 | 0.0427161 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0415957 |
| ZNF292 | zinc finger protein 292 | 0.0406078 |
| TMEM165 | transmembrane protein 165 | 0.0402764 |
| ABI1 | abl-interactor 1 | 0.0394813 |
| ECE1 | endothelin converting enzyme 1 | 0.0375058 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0374994 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0360607 |
| H3-3B | H3.3 histone B | 0.0358498 |
| PTN | pleiotrophin | 0.035556 |
| RLF | rearranged L-myc fusion | 0.0353348 |
| RNF145 | ring finger protein 145 | 0.0352612 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0351797 |
| ARRDC3 | arrestin domain containing 3 | 0.0347751 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0347687 |
| FAM13A | family with sequence similarity 13, member A | 0.0342164 |
| S100A6 | S100 calcium binding protein A6 | 0.0333228 |
| CLEC1B | C-type lectin domain family 1, member B | 0.0333126 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0330408 |
| PPP3CC | protein phosphatase 3, catalytic subunit, gamma isozyme | 0.0327979 |
| RUNX1 | runt-related transcription factor 1 | 0.032749 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0323852 |
| MATR3 | matrin 3 | 0.0320106 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0314498 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0312062 |
| ANLN | anillin, actin binding protein | 0.0311707 |
| KIF1B | kinesin family member 1B | 0.0311062 |
| UPP1 | uridine phosphorylase 1 | 0.0306348 |
| GOLGA4 | golgin A4 | 0.0303751 |
| RPS12 | ribosomal protein S12 | 0.0300529 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0297422 |
| RNF24 | ring finger protein 24 | 0.0292106 |
| SYNJ2 | synaptojanin 2 | 0.029093 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0288509 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | 0.0288192 |
| PCM1 | pericentriolar material 1 | 0.0287646 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0282314 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0282055 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0281446 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0277157 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0275821 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0274125 |
| WTAP | Wilms tumor 1 associated protein | 0.0273842 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0272828 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0271092 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0270417 |
| FTL | ferritin, light polypeptide | 0.0265603 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0262565 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0262354 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0261385 |
| ITM2B | integral membrane protein 2B | 0.0260711 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0259569 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0258117 |
| DENND5A | DENN/MADD domain containing 5A | 0.0255655 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0252866 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.0252745 |
| TMEM39A | transmembrane protein 39A | 0.0252145 |
| FLOT1 | flotillin 1 | 0.024905 |
| RINT1 | RAD50 interactor 1 | 0.0248395 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 0.0248394 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0248228 |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.0246143 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0245411 |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) | 0.0245102 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0244914 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0244709 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0241621 |
| WASF2 | WAS protein family, member 2 | 0.024116 |
| CCNI | cyclin I | 0.0239764 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.023727 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | 0.0237059 |
| FNBP4 | formin binding protein 4 | 0.0236783 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.0236245 |
| HPCAL1 | hippocalcin-like 1 | 0.0235602 |
| USP33 | ubiquitin specific peptidase 33 | 0.023515 |
| CEP170 | centrosomal protein 170kDa | 0.0234232 |
| TNPO3 | transportin 3 | 0.0233587 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0233564 |
| RACK1 | receptor for activated C kinase 1 | 0.0232727 |
| FNBP1L | formin binding protein 1-like | 0.0229056 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.413635 |
| COL6A3 | collagen, type VI, alpha 3 | -0.203028 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.157886 |
| CDH13 | cadherin 13 | -0.117744 |
| FN1 | fibronectin 1 | -0.117219 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.101051 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0957452 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0845329 |
| VCL | vinculin | -0.0752606 |
| IL6 | interleukin 6 | -0.0738668 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0737346 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.071917 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0693641 |
| VEGFC | vascular endothelial growth factor C | -0.0642567 |
| EGFR | epidermal growth factor receptor | -0.0639303 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0601616 |
| COL5A1 | collagen, type V, alpha 1 | -0.060028 |
| NAV1 | neuron navigator 1 | -0.0595213 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0522046 |
| RASAL2 | RAS protein activator like 2 | -0.0515288 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0512495 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0512339 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0491815 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0487644 |
| LOX | lysyl oxidase | -0.0486898 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0465826 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0452893 |
| ACTG1 | actin gamma 1 | -0.0450608 |
| EFNA5 | ephrin-A5 | -0.0446663 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0439297 |
| RAI14 | retinoic acid induced 14 | -0.0433347 |
| RRBP1 | ribosome binding protein 1 | -0.0428973 |
| POTEF | POTE ankyrin domain family, member F | -0.0424457 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.042109 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0408854 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0402099 |
| PRKCA | protein kinase C, alpha | -0.0397741 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0388687 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.037935 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0379185 |
| SEC24D | SEC24 family member D | -0.0378803 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.0375285 |
| HDLBP | high density lipoprotein binding protein | -0.0369729 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0368983 |
| GLIS3 | GLIS family zinc finger 3 | -0.0367636 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0364973 |
| NABP1 | nucleic acid binding protein 1 | -0.0352789 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0342634 |
| LOXL2 | lysyl oxidase-like 2 | -0.0331433 |
| EXOC4 | exocyst complex component 4 | -0.0331276 |
| VEGFA | vascular endothelial growth factor A | -0.0330609 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0328936 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0328158 |
| COL1A1 | collagen, type I, alpha 1 | -0.0325844 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.032022 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0315099 |
| DST | dystonin | -0.0313966 |
| FNIP1 | folliculin interacting protein 1 | -0.0312994 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0309867 |
| ATXN1 | ataxin 1 | -0.0309215 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0298734 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0293339 |
| NBAS | neuroblastoma amplified sequence | -0.0293143 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0293104 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0292605 |
| INHBA | inhibin, beta A | -0.0290615 |
| NECTIN3 | nectin cell adhesion molecule 3 | -0.0285451 |
| SMYD3 | SET and MYND domain containing 3 | -0.0284931 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0283851 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0282781 |
| COL5A2 | collagen, type V, alpha 2 | -0.0282338 |
| ALK | anaplastic lymphoma receptor tyrosine kinase | -0.0281432 |
| MAP1B | microtubule-associated protein 1B | -0.0277234 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0275354 |
| ALG11 | ALG11, alpha-1,2-mannosyltransferase | -0.026863 |
| COG6 | component of oligomeric golgi complex 6 | -0.026654 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.026156 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.0258646 |
| MYO9A | myosin IXA | -0.0256707 |
| SEC24A | SEC24 family member A | -0.0256375 |
| FBN1 | fibrillin 1 | -0.0254265 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.025184 |
| INTS6 | integrator complex subunit 6 | -0.0247434 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0246776 |
| EXT1 | exostosin glycosyltransferase 1 | -0.02467 |
| ATM | ATM serine/threonine kinase | -0.0246361 |
| HM13 | histocompatibility (minor) 13 | -0.0246275 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.0245459 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0243366 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0243337 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0242832 |
| LCOR | ligand dependent nuclear receptor corepressor | -0.0241862 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0241577 |
| SETBP1 | SET binding protein 1 | -0.0241478 |
| FUS | FUS RNA binding protein | -0.0240245 |
| KYNU | kynureninase | -0.0240013 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.0237627 |
| FLNA | filamin A, alpha | -0.0237403 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0234748 |
| MYOF | myoferlin | -0.0234445 |
