| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ralimetinib dimesylate perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ralimetinib dimesylate_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAM13A | family with sequence similarity 13, member A | 0.0494824 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0472362 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0451757 |
| RNF145 | ring finger protein 145 | 0.0418316 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0395167 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0391234 |
| OGA | O-GlcNAcase | 0.0364006 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0352535 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.030946 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0304827 |
| TXNIP | thioredoxin interacting protein | 0.0288987 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0288137 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0283 |
| HELZ | helicase with zinc finger | 0.0275825 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0272547 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0262987 |
| RPS12 | ribosomal protein S12 | 0.0254493 |
| ZNF292 | zinc finger protein 292 | 0.0252082 |
| NEK7 | NIMA-related kinase 7 | 0.0245817 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0242852 |
| YBX3 | Y box binding protein 3 | 0.0239793 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0237695 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0236453 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.022892 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.022731 |
| CDC73 | cell division cycle 73 | 0.0225803 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0222804 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0219668 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0210643 |
| COPA | coatomer protein complex, subunit alpha | 0.020978 |
| SUCO | SUN domain containing ossification factor | 0.0208649 |
| PRELID2 | PRELI domain containing 2 | 0.0205976 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0198858 |
| WDR43 | WD repeat domain 43 | 0.0198786 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0198227 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0193786 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0190959 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0189167 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0187266 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0183102 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0181984 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0178368 |
| MT2A | metallothionein 2A | 0.0178012 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0177891 |
| RPS3 | ribosomal protein S3 | 0.0177116 |
| RBM39 | RNA binding motif protein 39 | 0.0176367 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0174704 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0174655 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0174431 |
| WTAP | Wilms tumor 1 associated protein | 0.0172182 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.016995 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0167769 |
| CREBRF | CREB3 regulatory factor | 0.0160887 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0160072 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0157752 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0157234 |
| NUP58 | nucleoporin 58 | 0.0156422 |
| SLTM | SAFB-like, transcription modulator | 0.015537 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0154903 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0154276 |
| TFG | TRK-fused gene | 0.0154119 |
| COG5 | component of oligomeric golgi complex 5 | 0.0153281 |
| RBM25 | RNA binding motif protein 25 | 0.0152141 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.0151788 |
| VIRMA | vir like m6A methyltransferase associated | 0.0151616 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0151092 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0150753 |
| USP3 | ubiquitin specific peptidase 3 | 0.0150459 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0149421 |
| TNPO3 | transportin 3 | 0.0148372 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0147851 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0147529 |
| SEPTIN7 | septin 7 | 0.0147372 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0147151 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0146976 |
| XPO1 | exportin 1 | 0.0146562 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0146384 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0142847 |
| MYO1B | myosin IB | 0.014271 |
| USP33 | ubiquitin specific peptidase 33 | 0.0142659 |
| KCTD3 | potassium channel tetramerization domain containing 3 | 0.0142022 |
| PELO | pelota homolog (Drosophila) | 0.0141819 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0140118 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0138897 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0138847 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0138821 |
| ORC4 | origin recognition complex, subunit 4 | 0.0138049 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.0137894 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0137802 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0137366 |
| NCKAP1 | NCK-associated protein 1 | 0.0137337 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0136436 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.01358 |
| CDK19 | cyclin-dependent kinase 19 | 0.0134797 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0134422 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0133841 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.013376 |
| MIS18BP1 | MIS18 binding protein 1 | 0.013167 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0131115 |
| RC3H1 | ring finger and CCCH-type domains 1 | 0.0130786 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.40441 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.252563 |
| NRG1 | neuregulin 1 | -0.239342 |
| FN1 | fibronectin 1 | -0.215213 |
| HMGA2 | high mobility group AT-hook 2 | -0.139243 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.118239 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.108488 |
| CANX | calnexin | -0.086148 |
| SQSTM1 | sequestosome 1 | -0.0844623 |
| ASPH | aspartate beta-hydroxylase | -0.0809359 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0749956 |
| GLIS3 | GLIS family zinc finger 3 | -0.0740402 |
| ITGA1 | integrin, alpha 1 | -0.0706757 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0674857 |
| VCL | vinculin | -0.0597259 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0581212 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0550322 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0544334 |
| EFNA5 | ephrin-A5 | -0.0544195 |
| RAI14 | retinoic acid induced 14 | -0.0513811 |
| ACTG1 | actin gamma 1 | -0.0504591 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.049676 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0475252 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0463163 |
| PTMA | prothymosin, alpha | -0.0451656 |
| TMSB4X | thymosin beta 4, X-linked | -0.0439798 |
| HLA-B | major histocompatibility complex, class I, B | -0.0438372 |
| SYT1 | synaptotagmin I | -0.0424541 |
| POTEF | POTE ankyrin domain family, member F | -0.0403251 |
| PLIN2 | perilipin 2 | -0.0395197 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0392068 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0391619 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0374375 |
| AEBP2 | AE binding protein 2 | -0.0359996 |
| S100A6 | S100 calcium binding protein A6 | -0.0343458 |
| LOXL2 | lysyl oxidase-like 2 | -0.0341307 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0332023 |
| NRP1 | neuropilin 1 | -0.0331586 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0325434 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.032349 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.031975 |
| H1-0 | H1.0 linker histone | -0.0319685 |
| UBC | ubiquitin C | -0.0319481 |
| GRB10 | growth factor receptor-bound protein 10 | -0.031231 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0311309 |
| PALLD | palladin, cytoskeletal associated protein | -0.0309005 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0305718 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0302901 |
| OSMR | oncostatin M receptor | -0.0302412 |
| MAP1B | microtubule-associated protein 1B | -0.0300024 |
| TMEM156 | transmembrane protein 156 | -0.02999 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0297693 |
| NDRG1 | N-myc downstream regulated 1 | -0.0295319 |
| TGFA | transforming growth factor, alpha | -0.0294154 |
| FTL | ferritin, light polypeptide | -0.029245 |
| S100A10 | S100 calcium binding protein A10 | -0.0290527 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0286677 |
| FBXO11 | F-box protein 11 | -0.0284242 |
| TMSB10 | thymosin beta 10 | -0.0275428 |
| IER3 | immediate early response 3 | -0.0275057 |
| SFTPA2 | surfactant protein A2 | -0.027454 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0272588 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0262824 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0261434 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0260764 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0254831 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0252227 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0251233 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0247941 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0247932 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0244404 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.02442 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.024249 |
| INTS6 | integrator complex subunit 6 | -0.0241298 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0240039 |
| RRBP1 | ribosome binding protein 1 | -0.0235023 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0229354 |
| TNS3 | tensin 3 | -0.0224931 |
| AHNAK | AHNAK nucleoprotein | -0.0224785 |
| RPS11 | ribosomal protein S11 | -0.0222213 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0222045 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0221709 |
| CALU | calumenin | -0.0220899 |
| PRKCA | protein kinase C, alpha | -0.0220894 |
| CUX1 | cut-like homeobox 1 | -0.0219836 |
| ARF1 | ADP-ribosylation factor 1 | -0.0218448 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0215936 |
| RAB31 | RAB31, member RAS oncogene family | -0.0215319 |
| LOX | lysyl oxidase | -0.0214836 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.021459 |
| ENO1 | enolase 1, (alpha) | -0.0213549 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0213196 |
| PDLIM5 | PDZ and LIM domain 5 | -0.021279 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0209942 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0209046 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.020868 |
| ATXN1 | ataxin 1 | -0.020496 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0204745 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.020429 |
| HPCAL1 | hippocalcin-like 1 | -0.0203617 |
