| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ralimetinib dimesylate perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ralimetinib dimesylate_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.100454 |
| RPS12 | ribosomal protein S12 | 0.0735131 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0661902 |
| FLNA | filamin A, alpha | 0.0507436 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0465482 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0440794 |
| RPS3 | ribosomal protein S3 | 0.0430513 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0415909 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0415569 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0413736 |
| DST | dystonin | 0.0380869 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0380784 |
| RPS17 | ribosomal protein S17 | 0.0353213 |
| RPL37A | ribosomal protein L37a | 0.0346085 |
| DSPP | dentin sialophosphoprotein | 0.0336887 |
| SMYD3 | SET and MYND domain containing 3 | 0.0334048 |
| SET | SET nuclear proto-oncogene | 0.0318839 |
| RPL13A | ribosomal protein L13a | 0.0313095 |
| RPL37 | ribosomal protein L37 | 0.0308074 |
| SMAD3 | SMAD family member 3 | 0.0306729 |
| NEBL | nebulette | 0.0306529 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0305114 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.027801 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0274544 |
| ASPH | aspartate beta-hydroxylase | 0.0271651 |
| YAP1 | Yes-associated protein 1 | 0.0270194 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0267451 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0261952 |
| RPL12 | ribosomal protein L12 | 0.0254772 |
| LIMA1 | LIM domain and actin binding 1 | 0.0254507 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0252764 |
| TUFT1 | tuftelin 1 | 0.0243171 |
| RPL9 | ribosomal protein L9 | 0.0236059 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0233279 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0231205 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.023031 |
| WWC1 | WW and C2 domain containing 1 | 0.0225758 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0225644 |
| HOXB6 | homeobox B6 | 0.0225349 |
| RPL26 | ribosomal protein L26 | 0.0224527 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0224133 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0221927 |
| RPS6 | ribosomal protein S6 | 0.0221766 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0219291 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0216029 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0215702 |
| RPLP1 | ribosomal protein, large, P1 | 0.0213593 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0210541 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0210039 |
| GPHN | gephyrin | 0.0208499 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | 0.0205877 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.02054 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0199163 |
| KRT8 | keratin 8, type II | 0.0198175 |
| MATR3 | matrin 3 | 0.0197865 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0194965 |
| IL18 | interleukin 18 | 0.0193089 |
| LRRC1 | leucine rich repeat containing 1 | 0.0191408 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0190472 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0190259 |
| PLEC | plectin | 0.0190051 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.018202 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0178748 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0178396 |
| FHL2 | four and a half LIM domains 2 | 0.0178396 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0175454 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0175103 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0172883 |
| DIAPH1 | diaphanous-related formin 1 | 0.0171625 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0171421 |
| KIZ | kizuna centrosomal protein | 0.017139 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0170999 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0170536 |
| HOXA3 | homeobox A3 | 0.0170186 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0169661 |
| WWOX | WW domain containing oxidoreductase | 0.0169563 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0169289 |
| CEP250 | centrosomal protein 250kDa | 0.0168901 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0167897 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0166495 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0165826 |
| H2AC6 | H2A clustered histone 6 | 0.0164913 |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) | 0.0163943 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0163266 |
| PNN | pinin, desmosome associated protein | 0.0162753 |
| RPL30 | ribosomal protein L30 | 0.0161364 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0160922 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0159698 |
| ITGB5 | integrin, beta 5 | 0.0158387 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0157937 |
| RPL36 | ribosomal protein L36 | 0.015741 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0156634 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0156185 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0156097 |
| AFDN | afadin, adherens junction formation factor | 0.0155571 |
| RPS8 | ribosomal protein S8 | 0.0155099 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0155077 |
| HOXB3 | homeobox B3 | 0.0154773 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0154314 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0153715 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.210227 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.177754 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.154612 |
| FTL | ferritin, light polypeptide | -0.140166 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0966061 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0905515 |
| H1-0 | H1.0 linker histone | -0.0895966 |
| UBC | ubiquitin C | -0.088325 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0864023 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.074669 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0667104 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0642725 |
| KRT18 | keratin 18, type I | -0.0633679 |
| EZR | ezrin | -0.061243 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0597256 |
| EGR1 | early growth response 1 | -0.0596546 |
| GOLGA4 | golgin A4 | -0.0588981 |
| TMEM123 | transmembrane protein 123 | -0.0567387 |
| IER3 | immediate early response 3 | -0.0553665 |
| CD2AP | CD2-associated protein | -0.0550653 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0544097 |
| TOP1 | topoisomerase (DNA) I | -0.0542497 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0520731 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0518065 |
| NDRG1 | N-myc downstream regulated 1 | -0.0509181 |
| RBM39 | RNA binding motif protein 39 | -0.0486665 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0485801 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0477625 |
| TMSB10 | thymosin beta 10 | -0.0470537 |
| BCL2L1 | BCL2-like 1 | -0.0466998 |
| CANX | calnexin | -0.0458261 |
| FRMD5 | FERM domain containing 5 | -0.044299 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0442776 |
| RAB7A | RAB7A, member RAS oncogene family | -0.043521 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0429595 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0426439 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0425049 |
| RPL8 | ribosomal protein L8 | -0.0421308 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0419096 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0412576 |
| EHBP1 | EH domain binding protein 1 | -0.0409567 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0382798 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0373984 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0369194 |
| GNAS | GNAS complex locus | -0.0368832 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0363002 |
| CUX1 | cut-like homeobox 1 | -0.0362041 |
| ACTN4 | actinin, alpha 4 | -0.0361221 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -0.0356859 |
| S100A10 | S100 calcium binding protein A10 | -0.0356113 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0355334 |
| OXSR1 | oxidative stress responsive 1 | -0.0353026 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0352297 |
| NOP58 | NOP58 ribonucleoprotein | -0.0349796 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0349 |
| TPX2 | TPX2, microtubule-associated | -0.0348821 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0347647 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0347509 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0343389 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0342742 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0341747 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0341229 |
| FBXO11 | F-box protein 11 | -0.033274 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0325364 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0322726 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0317952 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0314735 |
| SQSTM1 | sequestosome 1 | -0.0312371 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0311594 |
| SETD5 | SET domain containing 5 | -0.0310862 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0308753 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0304451 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0298919 |
| PGK1 | phosphoglycerate kinase 1 | -0.0297438 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0295721 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0295401 |
| USP3 | ubiquitin specific peptidase 3 | -0.0292116 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0289582 |
| FNBP4 | formin binding protein 4 | -0.0288102 |
| NF1 | neurofibromin 1 | -0.0287821 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0287137 |
| TOB1 | transducer of ERBB2, 1 | -0.0286922 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0285453 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0284861 |
| PARD6B | par-6 family cell polarity regulator beta | -0.0279974 |
| HDLBP | high density lipoprotein binding protein | -0.0278113 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.027803 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0275749 |
| MX2 | MX dynamin-like GTPase 2 | -0.027465 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0273579 |
| RHEB | Ras homolog enriched in brain | -0.0272628 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0272229 |
| BBX | bobby sox homolog (Drosophila) | -0.0268657 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0268475 |
| MSI2 | musashi RNA-binding protein 2 | -0.0264156 |
| ARF1 | ADP-ribosylation factor 1 | -0.0262906 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0261627 |
| MXD1 | MAX dimerization protein 1 | -0.0260443 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0259282 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0257616 |
