| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ralimetinib dimesylate perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ralimetinib dimesylate_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0678912 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0650819 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0640468 |
| PCBP2 | poly(rC) binding protein 2 | 0.0603626 |
| CD46 | CD46 molecule, complement regulatory protein | 0.057907 |
| RPS12 | ribosomal protein S12 | 0.0566631 |
| OXR1 | oxidation resistance 1 | 0.0456039 |
| ZNF292 | zinc finger protein 292 | 0.0423322 |
| MACC1 | metastasis associated in colon cancer 1 | 0.040692 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0394536 |
| RBM26 | RNA binding motif protein 26 | 0.0387103 |
| PCM1 | pericentriolar material 1 | 0.0371245 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0366234 |
| JMJD1C | jumonji domain containing 1C | 0.0338553 |
| OGA | O-GlcNAcase | 0.0336981 |
| PTEN | phosphatase and tensin homolog | 0.0334447 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0330899 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0319155 |
| TMF1 | TATA element modulatory factor 1 | 0.0311364 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0310082 |
| SET | SET nuclear proto-oncogene | 0.0309842 |
| HELZ | helicase with zinc finger | 0.0309363 |
| VIM | vimentin | 0.030702 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0301116 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0300098 |
| MATR3 | matrin 3 | 0.0299981 |
| ZNF148 | zinc finger protein 148 | 0.0299314 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0299279 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0297985 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0297818 |
| DST | dystonin | 0.0294909 |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.029454 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0294204 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0291783 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.028695 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0285766 |
| RUNX1 | runt-related transcription factor 1 | 0.0281697 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0281446 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0280438 |
| NKTR | natural killer cell triggering receptor | 0.0278272 |
| XPO1 | exportin 1 | 0.0277075 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0274008 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0271794 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0270279 |
| SETD5 | SET domain containing 5 | 0.026865 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0266806 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0262974 |
| NEBL | nebulette | 0.0256877 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0254154 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0251059 |
| PNN | pinin, desmosome associated protein | 0.0250718 |
| RPS3 | ribosomal protein S3 | 0.0248324 |
| KIZ | kizuna centrosomal protein | 0.0245913 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0245859 |
| USP33 | ubiquitin specific peptidase 33 | 0.0242387 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0238628 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.023519 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0234818 |
| VGLL4 | vestigial-like family member 4 | 0.0232267 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0229552 |
| YEATS2 | YEATS domain containing 2 | 0.0229187 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0228626 |
| EXOC1 | exocyst complex component 1 | 0.0227665 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0226932 |
| ETNK1 | ethanolamine kinase 1 | 0.0225258 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0224161 |
| SNX9 | sorting nexin 9 | 0.0221565 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0221126 |
| DSPP | dentin sialophosphoprotein | 0.0219907 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0219876 |
| GOLGA4 | golgin A4 | 0.0216953 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0215917 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0215622 |
| SERINC3 | serine incorporator 3 | 0.0215316 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.021385 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0213597 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0212618 |
| COG5 | component of oligomeric golgi complex 5 | 0.0212056 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0210372 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0209656 |
| RPL3 | ribosomal protein L3 | 0.0209499 |
| PRELID2 | PRELI domain containing 2 | 0.0209135 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0206983 |
| CCDC82 | coiled-coil domain containing 82 | 0.0206674 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.0206038 |
| TM7SF3 | transmembrane 7 superfamily member 3 | 0.0204814 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0203722 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0201863 |
| USP47 | ubiquitin specific peptidase 47 | 0.0201534 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.020092 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0200644 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0199854 |
| CKAP5 | cytoskeleton associated protein 5 | 0.019785 |
| CDK19 | cyclin-dependent kinase 19 | 0.0197213 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0196595 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0196005 |
| RNF149 | ring finger protein 149 | 0.0192544 |
| TPR | translocated promoter region, nuclear basket protein | 0.0190649 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0190473 |
| FNBP1L | formin binding protein 1-like | 0.0190028 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.237283 |
| NAV2 | neuron navigator 2 | -0.176471 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.124962 |
| ACTG1 | actin gamma 1 | -0.111609 |
| TMSB10 | thymosin beta 10 | -0.11063 |
| INTS6 | integrator complex subunit 6 | -0.101934 |
| PTMA | prothymosin, alpha | -0.0970992 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0969971 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0883185 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.088168 |
| CCND1 | cyclin D1 | -0.0870846 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0869979 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0820808 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0817346 |
| VCL | vinculin | -0.080145 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.079693 |
| CDH13 | cadherin 13 | -0.0736788 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.06399 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0627049 |
| AHNAK | AHNAK nucleoprotein | -0.0623703 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.057305 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0553763 |
| ACTN4 | actinin, alpha 4 | -0.0503298 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0492614 |
| RPS24 | ribosomal protein S24 | -0.046762 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0464931 |
| RPL35A | ribosomal protein L35a | -0.0461641 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0458688 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0446629 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0443077 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0442301 |
| RPLP1 | ribosomal protein, large, P1 | -0.0436986 |
| IER3 | immediate early response 3 | -0.0426544 |
| ANXA2 | annexin A2 | -0.0414664 |
| KRT18 | keratin 18, type I | -0.0411189 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0398267 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0396749 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.039309 |
| RPL32 | ribosomal protein L32 | -0.039009 |
| RPS23 | ribosomal protein S23 | -0.0384314 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0377027 |
| RPS11 | ribosomal protein S11 | -0.0373495 |
| RPS21 | ribosomal protein S21 | -0.0371199 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0367536 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0365182 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0363139 |
| MYO1D | myosin ID | -0.0355069 |
| RPL38 | ribosomal protein L38 | -0.0353162 |
| EGR1 | early growth response 1 | -0.0351093 |
| S100A10 | S100 calcium binding protein A10 | -0.0350309 |
| RPL34 | ribosomal protein L34 | -0.0349729 |
| H1-0 | H1.0 linker histone | -0.0347331 |
| FUS | FUS RNA binding protein | -0.0347144 |
| RPL23 | ribosomal protein L23 | -0.0332959 |
| TUBB | tubulin, beta class I | -0.032936 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.032578 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0322093 |
| HDAC4 | histone deacetylase 4 | -0.0317467 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0317344 |
| HMGB1 | high mobility group box 1 | -0.0316545 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0314637 |
| FLNB | filamin B, beta | -0.0313961 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0312691 |
| RPS5 | ribosomal protein S5 | -0.031174 |
| RPS27A | ribosomal protein S27a | -0.0308258 |
| RPS15 | ribosomal protein S15 | -0.0307886 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0303612 |
| TFRC | transferrin receptor | -0.0301179 |
| FRMD5 | FERM domain containing 5 | -0.0300625 |
| RPLP2 | ribosomal protein, large, P2 | -0.0300329 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | -0.0300022 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0298708 |
| ASPH | aspartate beta-hydroxylase | -0.0295922 |
| SQSTM1 | sequestosome 1 | -0.0293153 |
| IGF1R | insulin-like growth factor 1 receptor | -0.029296 |
| RPS13 | ribosomal protein S13 | -0.0292932 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0290195 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.028827 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0286433 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0286308 |
| RPS19 | ribosomal protein S19 | -0.0284994 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0282436 |
| MT2A | metallothionein 2A | -0.0273207 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0271465 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.027035 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0269447 |
| RPS6 | ribosomal protein S6 | -0.0268843 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0264704 |
| RPL8 | ribosomal protein L8 | -0.0264149 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0262513 |
| PLEC | plectin | -0.0262503 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0261793 |
| CDK6 | cyclin-dependent kinase 6 | -0.026152 |
| KRT8 | keratin 8, type II | -0.025968 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0251821 |
| TMEM123 | transmembrane protein 123 | -0.0250774 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0247576 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0244105 |
| CUX1 | cut-like homeobox 1 | -0.0240209 |
| FHIT | fragile histidine triad | -0.0240121 |
