| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ralimetinib dimesylate perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ralimetinib dimesylate_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.08458 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0793385 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0793183 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0694017 |
| TMSB10 | thymosin beta 10 | 0.0664001 |
| FAM13A | family with sequence similarity 13, member A | 0.0611561 |
| RPS12 | ribosomal protein S12 | 0.0579072 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0528569 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0508188 |
| RPS6 | ribosomal protein S6 | 0.0501507 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0484311 |
| MT2A | metallothionein 2A | 0.0456349 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0444254 |
| RPS3 | ribosomal protein S3 | 0.0441424 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0432486 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0431891 |
| PRRC2C | proline-rich coiled-coil 2C | 0.041851 |
| RPS17 | ribosomal protein S17 | 0.041265 |
| GPHN | gephyrin | 0.0412486 |
| RPL12 | ribosomal protein L12 | 0.0411678 |
| CAVIN1 | caveolae associated protein 1 | 0.0381257 |
| RPL26 | ribosomal protein L26 | 0.0369726 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0356943 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0354348 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0353939 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0351446 |
| RPL35A | ribosomal protein L35a | 0.0349386 |
| RPL23 | ribosomal protein L23 | 0.0342808 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0329794 |
| NAV2 | neuron navigator 2 | 0.0323399 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0320203 |
| COL5A2 | collagen, type V, alpha 2 | 0.0319777 |
| RPS19 | ribosomal protein S19 | 0.0312017 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0308487 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0304443 |
| RPS8 | ribosomal protein S8 | 0.0300725 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0296503 |
| RPL7 | ribosomal protein L7 | 0.0291032 |
| RPL37A | ribosomal protein L37a | 0.0289981 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0279703 |
| RACK1 | receptor for activated C kinase 1 | 0.0279515 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0277729 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0277554 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0274808 |
| RPS24 | ribosomal protein S24 | 0.0266369 |
| B2M | beta-2-microglobulin | 0.0266228 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0266018 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0264029 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0260158 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0256981 |
| RUNX1 | runt-related transcription factor 1 | 0.0251366 |
| RPL19 | ribosomal protein L19 | 0.024961 |
| RPL13A | ribosomal protein L13a | 0.0247087 |
| FTL | ferritin, light polypeptide | 0.0243281 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0242838 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0241573 |
| RPL18 | ribosomal protein L18 | 0.02385 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0235972 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0234635 |
| RPL5 | ribosomal protein L5 | 0.0234269 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0234206 |
| RPL9 | ribosomal protein L9 | 0.023291 |
| RPLP1 | ribosomal protein, large, P1 | 0.023164 |
| MEIS1 | Meis homeobox 1 | 0.0230754 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0227851 |
| RPL36 | ribosomal protein L36 | 0.0226081 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0225812 |
| RPL11 | ribosomal protein L11 | 0.0225054 |
| RPLP2 | ribosomal protein, large, P2 | 0.0221742 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.022056 |
| RPLP0 | ribosomal protein, large, P0 | 0.0219473 |
| RPS25 | ribosomal protein S25 | 0.0213237 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0210264 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0208701 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0207898 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0206846 |
| KIAA1217 | KIAA1217 | 0.0205359 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0203942 |
| TPI1 | triosephosphate isomerase 1 | 0.0202715 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0202295 |
| MMP2 | matrix metallopeptidase 2 | 0.0200575 |
| COL3A1 | collagen, type III, alpha 1 | 0.0198957 |
| SON | SON DNA binding protein | 0.0196777 |
| FRMD6 | FERM domain containing 6 | 0.0196496 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0195649 |
| WTAP | Wilms tumor 1 associated protein | 0.0195167 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.019396 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0193871 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0192425 |
| MED13L | mediator complex subunit 13-like | 0.0191267 |
| SET | SET nuclear proto-oncogene | 0.0190328 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0190281 |
| PLPP3 | phospholipid phosphatase 3 | 0.0189256 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | 0.0187035 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0186391 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0186023 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0184202 |
| KLF6 | Kruppel-like factor 6 | 0.0182824 |
| RPL28 | ribosomal protein L28 | 0.0182454 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0182334 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.289396 |
| FN1 | fibronectin 1 | -0.249311 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.2218 |
| MMP1 | matrix metallopeptidase 1 | -0.13307 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.130386 |
| STC1 | stanniocalcin 1 | -0.12513 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.11526 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.102271 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0907999 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0892648 |
| COL1A1 | collagen, type I, alpha 1 | -0.0753057 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0721972 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0654223 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0650168 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0647318 |
| CALU | calumenin | -0.0627048 |
| AHNAK | AHNAK nucleoprotein | -0.0626774 |
| DST | dystonin | -0.062663 |
| ADM | adrenomedullin | -0.0609935 |
| LOX | lysyl oxidase | -0.0594219 |
| NDRG1 | N-myc downstream regulated 1 | -0.0541475 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0540245 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0536444 |
| EMP1 | epithelial membrane protein 1 | -0.0497197 |
| CANX | calnexin | -0.0472279 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0457837 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0442155 |
| FBN1 | fibrillin 1 | -0.0432472 |
| CALR | calreticulin | -0.0423462 |
| VIM | vimentin | -0.042186 |
| VCL | vinculin | -0.0402518 |
| UBC | ubiquitin C | -0.0399551 |
| RAI14 | retinoic acid induced 14 | -0.0378012 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0370022 |
| NPTX1 | neuronal pentraxin I | -0.0363446 |
| CD44 | CD44 molecule (Indian blood group) | -0.0336412 |
| COL1A2 | collagen, type I, alpha 2 | -0.033418 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0326176 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0322922 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0319944 |
| MMP12 | matrix metallopeptidase 12 | -0.0315004 |
| PDE8A | phosphodiesterase 8A | -0.0308391 |
| CD99 | CD99 molecule | -0.0303596 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0303022 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0302157 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0274142 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0272505 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.02719 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0267695 |
| CENPF | centromere protein F, 350/400kDa | -0.0266419 |
| IKBIP | IKBKB interacting protein | -0.0265696 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0264625 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0264101 |
| FSTL1 | follistatin-like 1 | -0.0253803 |
| S100A10 | S100 calcium binding protein A10 | -0.0250542 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.024883 |
| WASF2 | WAS protein family, member 2 | -0.0247883 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0246925 |
| CDH13 | cadherin 13 | -0.024552 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0244605 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0244202 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0242364 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0237979 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0236685 |
| GLG1 | golgi glycoprotein 1 | -0.0235994 |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | -0.023378 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0228414 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0226339 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -0.0225132 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0222677 |
| AAK1 | AP2 associated kinase 1 | -0.022049 |
| ZFHX3 | zinc finger homeobox 3 | -0.0219776 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0219205 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | -0.0217962 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0217564 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0217015 |
| TCF12 | transcription factor 12 | -0.0215891 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0215552 |
| COL5A1 | collagen, type V, alpha 1 | -0.0212868 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0212802 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0208275 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.020784 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0207487 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0207187 |
| NABP1 | nucleic acid binding protein 1 | -0.0206705 |
| TPM4 | tropomyosin 4 | -0.0206532 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0205352 |
| FUS | FUS RNA binding protein | -0.0204879 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0203605 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0203315 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0203307 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0202055 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | -0.0201122 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0199639 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.019897 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0198557 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0196787 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0196069 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0195523 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0194853 |
