Raloxifene Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A benzothiophene that has formula C28H27NO4S. (Chemical Entities of Biological Interest Ontology, CHEBI_8772)
External Link http://ctdbase.org/detail.go?type=chem&acc=D020849
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Genes

101 genes/proteins interacting with the chemical Raloxifene from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACVRL1 activin A receptor type II-like 1
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
AOX1 aldehyde oxidase 1
AR androgen receptor
ARID5A AT rich interactive domain 5A (MRF1-like)
BAD BCL2-associated agonist of cell death
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BGLAP bone gamma-carboxyglutamate (gla) protein
CASP3 caspase 3, apoptosis-related cysteine peptidase
CAT catalase
CAV1 caveolin 1, caveolae protein, 22kDa
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CCNA2 cyclin A2
CCNB1 cyclin B1
CD40 CD40 molecule, TNF receptor superfamily member 5
CD80 CD80 molecule
CD86 CD86 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CKB creatine kinase, brain
CPB2 carboxypeptidase B2 (plasma)
CREBBP CREB binding protein
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DMBT1 deleted in malignant brain tumors 1
EGFR epidermal growth factor receptor
ENG endoglin
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
F11 coagulation factor XI
F12 coagulation factor XII (Hageman factor)
F8 coagulation factor VIII, procoagulant component
GH1 growth hormone 1
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPER1 G protein-coupled estrogen receptor 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP3 insulin-like growth factor binding protein 3
IL1B interleukin 1, beta
IL6 interleukin 6
JAK2 Janus kinase 2
KLRC3 killer cell lectin-like receptor subfamily C, member 3
LHB luteinizing hormone beta polypeptide
MAP2K6 mitogen-activated protein kinase kinase 6
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MKI67 marker of proliferation Ki-67
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MUC1 mucin 1, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCOA1 nuclear receptor coactivator 1
NCOA2 nuclear receptor coactivator 2
NCOA3 nuclear receptor coactivator 3
NCOR2 nuclear receptor corepressor 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOS2 nitric oxide synthase 2, inducible
PAWR PRKC, apoptosis, WT1, regulator
PCNA proliferating cell nuclear antigen
PGR progesterone receptor
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PRL prolactin
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROS1 protein S (alpha)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SHBG sex hormone-binding globulin
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TERT telomerase reverse transcriptase
TFF1 trefoil factor 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFB1 transforming growth factor, beta 1
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TRIM25 tripartite motif containing 25
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VWF von Willebrand factor
XDH xanthine dehydrogenase