| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ranolazine perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ranolazine_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.148953 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.12902 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.102738 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0962403 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0934562 |
| B2M | beta-2-microglobulin | 0.0739945 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0658806 |
| NAV2 | neuron navigator 2 | 0.060105 |
| FBN1 | fibrillin 1 | 0.0597392 |
| TMSB10 | thymosin beta 10 | 0.0594577 |
| SUCNR1 | succinate receptor 1 | 0.0543056 |
| SBF2 | SET binding factor 2 | 0.0539984 |
| GPC6 | glypican 6 | 0.0469574 |
| ATP13A3 | ATPase type 13A3 | 0.045855 |
| COL1A2 | collagen, type I, alpha 2 | 0.0443167 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0384041 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0361479 |
| SLC39A11 | solute carrier family 39, member 11 | 0.035182 |
| OGA | O-GlcNAcase | 0.0351521 |
| PGK1 | phosphoglycerate kinase 1 | 0.0345337 |
| HIP1 | huntingtin interacting protein 1 | 0.0341693 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0315361 |
| S100A10 | S100 calcium binding protein A10 | 0.0312157 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0307421 |
| CCND1 | cyclin D1 | 0.0306885 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0302679 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0301738 |
| CD44 | CD44 molecule (Indian blood group) | 0.0299947 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0299733 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0298447 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.029606 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0293928 |
| CENPF | centromere protein F, 350/400kDa | 0.0289433 |
| RPL35A | ribosomal protein L35a | 0.0288985 |
| MYOF | myoferlin | 0.0282848 |
| C1ORF21 | chromosome 1 open reading frame 21 | 0.0281847 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0279163 |
| PTMA | prothymosin, alpha | 0.0278116 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0276987 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0276417 |
| MED13L | mediator complex subunit 13-like | 0.0275797 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0266703 |
| RAD50 | RAD50 homolog (S. cerevisiae) | 0.0264425 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0264317 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0262771 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0258596 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.0258536 |
| CD109 | CD109 molecule | 0.0254526 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0253651 |
| HMGB2 | high mobility group box 2 | 0.0253193 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0252786 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0249046 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0246281 |
| HLA-A | major histocompatibility complex, class I, A | 0.0245484 |
| MATR3 | matrin 3 | 0.0243289 |
| XPO1 | exportin 1 | 0.0243062 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0240679 |
| ITGAV | integrin, alpha V | 0.0240056 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0238837 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0237831 |
| NGLY1 | N-glycanase 1 | 0.0236016 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0233116 |
| PPP3CC | protein phosphatase 3, catalytic subunit, gamma isozyme | 0.0232934 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0232894 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0231811 |
| APAF1 | apoptotic peptidase activating factor 1 | 0.0228309 |
| CTSB | cathepsin B | 0.0228157 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0227816 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0227536 |
| ANO6 | anoctamin 6 | 0.0226794 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0224704 |
| SEPTIN11 | septin 11 | 0.0224024 |
| S100A6 | S100 calcium binding protein A6 | 0.022307 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0223012 |
| FRMD4A | FERM domain containing 4A | 0.0222485 |
| DSTN | destrin (actin depolymerizing factor) | 0.0221078 |
| MT1X | metallothionein 1X | 0.0219716 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.021897 |
| CBX3 | chromobox homolog 3 | 0.0218409 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0218399 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0215955 |
| NAV1 | neuron navigator 1 | 0.0214059 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0213358 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0212924 |
| MSI2 | musashi RNA-binding protein 2 | 0.0212511 |
| SPAG9 | sperm associated antigen 9 | 0.021202 |
| PERP | PERP, TP53 apoptosis effector | 0.021151 |
| DST | dystonin | 0.0207766 |
| AAK1 | AP2 associated kinase 1 | 0.0207345 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0206761 |
| EXOC1 | exocyst complex component 1 | 0.0206377 |
| NBAS | neuroblastoma amplified sequence | 0.0206136 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0204401 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0203788 |
| ATXN2 | ataxin 2 | 0.0203231 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.0203106 |
| SETD5 | SET domain containing 5 | 0.0201392 |
| TMSB4X | thymosin beta 4, X-linked | 0.0200194 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0198218 |
| CEP192 | centrosomal protein 192kDa | 0.0195411 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.193914 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.155425 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.129826 |
| NDRG1 | N-myc downstream regulated 1 | -0.109726 |
| LOX | lysyl oxidase | -0.0901899 |
| PODXL | podocalyxin-like | -0.0794253 |
| MAP1B | microtubule-associated protein 1B | -0.0746919 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0651163 |
| COL5A1 | collagen, type V, alpha 1 | -0.0640127 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0610575 |
| TPM4 | tropomyosin 4 | -0.0553923 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0516887 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0497764 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0494516 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0487287 |
| C1D | C1D nuclear receptor corepressor | -0.048655 |
| THBS2 | thrombospondin 2 | -0.0480991 |
| VEGFA | vascular endothelial growth factor A | -0.0475567 |
| LOXL2 | lysyl oxidase-like 2 | -0.0448759 |
| SP100 | SP100 nuclear antigen | -0.0442156 |
| STC1 | stanniocalcin 1 | -0.0424771 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0420156 |
| POTEF | POTE ankyrin domain family, member F | -0.041533 |
| SEPTIN9 | septin 9 | -0.0405252 |
| FLNA | filamin A, alpha | -0.0373143 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0356648 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0349024 |
| EZR | ezrin | -0.0343552 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0342403 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0340193 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.033301 |
| MX2 | MX dynamin-like GTPase 2 | -0.0328356 |
| CLIC4 | chloride intracellular channel 4 | -0.0318585 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0314225 |
| L1CAM | L1 cell adhesion molecule | -0.0312068 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0309918 |
| CANX | calnexin | -0.0309044 |
| VIM | vimentin | -0.0308306 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0307604 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0307573 |
| TAPBP | TAP binding protein (tapasin) | -0.0304009 |
| MYADM | myeloid-associated differentiation marker | -0.0303456 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0299777 |
| AHNAK | AHNAK nucleoprotein | -0.0288826 |
| TPM3 | tropomyosin 3 | -0.0287869 |
| ENO1 | enolase 1, (alpha) | -0.0286506 |
| EGR1 | early growth response 1 | -0.0279649 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0279565 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0275802 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0272206 |
| CALR | calreticulin | -0.0270221 |
| EHBP1 | EH domain binding protein 1 | -0.0267607 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0265801 |
| VCL | vinculin | -0.0263141 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0263011 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0262312 |
| CUL4A | cullin 4A | -0.026048 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0259221 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0257286 |
| FOSL1 | FOS-like antigen 1 | -0.0256907 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0247545 |
| MNT | MAX network transcriptional repressor | -0.0246541 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0245152 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0241687 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0239401 |
| ASPH | aspartate beta-hydroxylase | -0.0235783 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0233294 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0229431 |
| PLEC | plectin | -0.0228769 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0227584 |
| MEF2D | myocyte enhancer factor 2D | -0.0227304 |
| BRD4 | bromodomain containing 4 | -0.0223385 |
| TAGLN2 | transgelin 2 | -0.0218586 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0215474 |
| VMP1 | vacuole membrane protein 1 | -0.0215446 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0213662 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0213278 |
| ANXA5 | annexin A5 | -0.0210865 |
| ANXA2 | annexin A2 | -0.0208355 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0207913 |
| EGFR | epidermal growth factor receptor | -0.0207383 |
| RIGI | RNA sensor RIG-I | -0.0206168 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0205489 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0204749 |
| TGFB1 | transforming growth factor, beta 1 | -0.0200324 |
| OPTN | optineurin | -0.0199637 |
| MSN | moesin | -0.0198875 |
| IFI44L | interferon-induced protein 44-like | -0.0197156 |
| BSG | basigin (Ok blood group) | -0.0196684 |
| MYO9B | myosin IXB | -0.0196024 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | -0.0195812 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0195715 |
| NABP1 | nucleic acid binding protein 1 | -0.0190398 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0190316 |
| COL5A2 | collagen, type V, alpha 2 | -0.0189297 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | -0.0189155 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0187864 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0187716 |
| HDLBP | high density lipoprotein binding protein | -0.0186163 |
| ACLY | ATP citrate lyase | -0.0183654 |
