| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ranolazine perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ranolazine_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HELZ | helicase with zinc finger | 0.100093 |
| FAM13A | family with sequence similarity 13, member A | 0.0826071 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0711922 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0692585 |
| LPIN1 | lipin 1 | 0.0677145 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0559729 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0543433 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0529735 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0520922 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0460335 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0444208 |
| SETD5 | SET domain containing 5 | 0.0428096 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0421623 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0406937 |
| FNBP1 | formin binding protein 1 | 0.038147 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0376009 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0373151 |
| CDC27 | cell division cycle 27 | 0.0362973 |
| PCBP2 | poly(rC) binding protein 2 | 0.0346453 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0345974 |
| MSI2 | musashi RNA-binding protein 2 | 0.0345966 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0345101 |
| MEF2A | myocyte enhancer factor 2A | 0.0341794 |
| PTK2 | protein tyrosine kinase 2 | 0.0338001 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0335761 |
| ZNF292 | zinc finger protein 292 | 0.0335571 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0335113 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0330718 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0327594 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.032536 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0324437 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0324204 |
| ENAH | enabled homolog (Drosophila) | 0.0323153 |
| RFX7 | regulatory factor X, 7 | 0.031712 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0301365 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0298974 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0298283 |
| RPS6 | ribosomal protein S6 | 0.0297399 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0293378 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.029272 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0291705 |
| OGA | O-GlcNAcase | 0.0288588 |
| DST | dystonin | 0.0286893 |
| SRP54 | signal recognition particle 54kDa | 0.0284243 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0283824 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.027998 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0279536 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0278441 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0277549 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0275692 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0275629 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.0273461 |
| ECT2 | epithelial cell transforming 2 | 0.0272337 |
| HMGB2 | high mobility group box 2 | 0.0272214 |
| SEPTIN9 | septin 9 | 0.0271014 |
| AFDN | afadin, adherens junction formation factor | 0.0268237 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0267151 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0266441 |
| INSIG2 | insulin induced gene 2 | 0.0265505 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0264934 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0262712 |
| GLG1 | golgi glycoprotein 1 | 0.0260937 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0260605 |
| DIAPH3 | diaphanous-related formin 3 | 0.026047 |
| CASC3 | cancer susceptibility candidate 3 | 0.0258925 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0255713 |
| SPAG9 | sperm associated antigen 9 | 0.0253833 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.02524 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 0.0251022 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 0.0250566 |
| CENPF | centromere protein F, 350/400kDa | 0.0248148 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.024713 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.024518 |
| TET2 | tet methylcytosine dioxygenase 2 | 0.0244864 |
| YEATS2 | YEATS domain containing 2 | 0.0243546 |
| PCNX1 | pecanex 1 | 0.0241976 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0241811 |
| RNF145 | ring finger protein 145 | 0.024086 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.024077 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0239552 |
| GDF15 | growth differentiation factor 15 | 0.0237337 |
| PKM | pyruvate kinase, muscle | 0.023674 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0232508 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0231701 |
| TRIM24 | tripartite motif containing 24 | 0.0231688 |
| ITGA1 | integrin, alpha 1 | 0.0229421 |
| NEK7 | NIMA-related kinase 7 | 0.0229075 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0226409 |
| ATL2 | atlastin GTPase 2 | 0.0226372 |
| NAA35 | N(alpha)-acetyltransferase 35, NatC auxiliary subunit | 0.0223994 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0223059 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0221888 |
| MRPL3 | mitochondrial ribosomal protein L3 | 0.0221612 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0221184 |
| GNAS | GNAS complex locus | 0.0219468 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0218859 |
| MTSS2 | MTSS I-BAR domain containing 2 | 0.0217839 |
| SMAD3 | SMAD family member 3 | 0.0217498 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.021691 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0215919 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | -0.122319 |
| IGF2 | insulin-like growth factor 2 | -0.119753 |
| FMN1 | formin 1 | -0.0674699 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0608567 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0605377 |
| SYT1 | synaptotagmin I | -0.049019 |
| RNF213 | ring finger protein 213 | -0.0454769 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.044182 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0437557 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0431641 |
| LIMA1 | LIM domain and actin binding 1 | -0.042217 |
| BPTF | bromodomain PHD finger transcription factor | -0.0411688 |
| NRP1 | neuropilin 1 | -0.0411132 |
| MAP1B | microtubule-associated protein 1B | -0.0399134 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0398822 |
| TMSB10 | thymosin beta 10 | -0.0395018 |
| COL3A1 | collagen, type III, alpha 1 | -0.0394726 |
| DNM3 | dynamin 3 | -0.0370802 |
| LSAMP | limbic system-associated membrane protein | -0.0358662 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0356821 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0347974 |
| CDK6 | cyclin-dependent kinase 6 | -0.0345853 |
| EGR1 | early growth response 1 | -0.0344471 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0343669 |
| FAM107B | family with sequence similarity 107, member B | -0.0332855 |
| COL1A1 | collagen, type I, alpha 1 | -0.0331172 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0325936 |
| NRG1 | neuregulin 1 | -0.0323062 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0320587 |
| VMP1 | vacuole membrane protein 1 | -0.0317057 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | -0.0314453 |
| CADM2 | cell adhesion molecule 2 | -0.0314315 |
| ANGPT1 | angiopoietin 1 | -0.0311751 |
| RPS24 | ribosomal protein S24 | -0.0307506 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0304508 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0296318 |
| ACTG1 | actin gamma 1 | -0.0295924 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0294489 |
| CRH | corticotropin releasing hormone | -0.0288636 |
| SCG2 | secretogranin II | -0.0284556 |
| HMBOX1 | homeobox containing 1 | -0.0277843 |
| MYO1E | myosin IE | -0.0274105 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0265761 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0265367 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.0264379 |
| CDK12 | cyclin-dependent kinase 12 | -0.026201 |
| PDE10A | phosphodiesterase 10A | -0.0261561 |
| TLE4 | transducin-like enhancer of split 4 | -0.0261131 |
| PLPP1 | phospholipid phosphatase 1 | -0.0260963 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0260357 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0259499 |
| IER3 | immediate early response 3 | -0.0256844 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0256405 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0256404 |
| RPS2 | ribosomal protein S2 | -0.0256233 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0253503 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0253059 |
| TPM4 | tropomyosin 4 | -0.0252865 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0250766 |
| STK38L | serine/threonine kinase 38 like | -0.0249936 |
| ZFHX3 | zinc finger homeobox 3 | -0.0246496 |
| PCNX4 | pecanex 4 | -0.0245747 |
| TMEM108 | transmembrane protein 108 | -0.0245739 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0245498 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0245223 |
| TPM1 | tropomyosin 1 (alpha) | -0.0242521 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0240669 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0239196 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0237193 |
| PLAT | plasminogen activator, tissue | -0.0235192 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.023272 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0229741 |
| VGF | VGF nerve growth factor inducible | -0.0228729 |
| MAP4 | microtubule-associated protein 4 | -0.0226885 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0226292 |
| CHD4 | chromodomain helicase DNA binding protein 4 | -0.0222196 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0221968 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0221952 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.021839 |
| DSTN | destrin (actin depolymerizing factor) | -0.0214646 |
| KLHL13 | kelch-like family member 13 | -0.0213914 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0212394 |
| EFNA5 | ephrin-A5 | -0.0211931 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0211095 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0210264 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0207645 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0206267 |
| RIGI | RNA sensor RIG-I | -0.020444 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0204274 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0202827 |
| CPNE8 | copine VIII | -0.0202145 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0201183 |
| ATRNL1 | attractin-like 1 | -0.0201103 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0200615 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0199328 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0199226 |
| MALT1 | MALT1 paracaspase | -0.0198637 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0198481 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0198393 |
| ZNF609 | zinc finger protein 609 | -0.019799 |
