| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ranolazine perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ranolazine_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0982206 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0869857 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0857549 |
| RNF43 | ring finger protein 43 | 0.0595904 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.057881 |
| B2M | beta-2-microglobulin | 0.055919 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0519067 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0507146 |
| TXNIP | thioredoxin interacting protein | 0.0492236 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0471215 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0451779 |
| MYO1E | myosin IE | 0.0420175 |
| RNF149 | ring finger protein 149 | 0.0419302 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0416866 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0411388 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0398261 |
| TMEM51 | transmembrane protein 51 | 0.0386405 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0372162 |
| IL20RA | interleukin 20 receptor, alpha | 0.0365992 |
| IFNGR1 | interferon gamma receptor 1 | 0.0342402 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | 0.0320386 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0314205 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.0300099 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0291355 |
| RPS6 | ribosomal protein S6 | 0.0288847 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0275506 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.027087 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0270501 |
| HLA-A | major histocompatibility complex, class I, A | 0.025979 |
| MEIS2 | Meis homeobox 2 | 0.0256936 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0255025 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0254205 |
| TC2N | tandem C2 domains, nuclear | 0.0248585 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0247242 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0246531 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0245592 |
| EFHD2 | EF-hand domain family, member D2 | 0.0239155 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0238342 |
| ZNF395 | zinc finger protein 395 | 0.023757 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0234966 |
| PDZD8 | PDZ domain containing 8 | 0.0234568 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0234421 |
| PTEN | phosphatase and tensin homolog | 0.0232789 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | 0.0232472 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0227746 |
| STK24 | serine/threonine kinase 24 | 0.0226532 |
| UBAP1 | ubiquitin associated protein 1 | 0.0225011 |
| MKI67 | marker of proliferation Ki-67 | 0.0224488 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0223457 |
| KLHL24 | kelch-like family member 24 | 0.022191 |
| ZNF148 | zinc finger protein 148 | 0.0218649 |
| NDRG1 | N-myc downstream regulated 1 | 0.021615 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0211902 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.020982 |
| TMEM62 | transmembrane protein 62 | 0.0206513 |
| FHL2 | four and a half LIM domains 2 | 0.0206059 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0204746 |
| PHIP | pleckstrin homology domain interacting protein | 0.0204727 |
| LIMA1 | LIM domain and actin binding 1 | 0.0204208 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0204156 |
| HELZ | helicase with zinc finger | 0.0200649 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0199645 |
| ZNF638 | zinc finger protein 638 | 0.019936 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0197542 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0197529 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0197232 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0195801 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0195561 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0193826 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0193417 |
| LNX1 | ligand of numb-protein X 1, E3 ubiquitin protein ligase | 0.0192333 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.01911 |
| ABHD2 | abhydrolase domain containing 2 | 0.0191017 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0187858 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0186859 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0185835 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0185829 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0185293 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0183816 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0182314 |
| SBF2 | SET binding factor 2 | 0.0180409 |
| FOSL2 | FOS-like antigen 2 | 0.0179982 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0179903 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0178959 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0178481 |
| PGK1 | phosphoglycerate kinase 1 | 0.0177642 |
| YEATS2 | YEATS domain containing 2 | 0.0177219 |
| RTN4 | reticulon 4 | 0.0176578 |
| ARRDC3 | arrestin domain containing 3 | 0.0175899 |
| PRELID2 | PRELI domain containing 2 | 0.0175657 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0174892 |
| EXOC1 | exocyst complex component 1 | 0.0174575 |
| PRRC2C | proline-rich coiled-coil 2C | 0.01741 |
| EHF | ets homologous factor | 0.0172249 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0172048 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0172032 |
| NEK7 | NIMA-related kinase 7 | 0.0171968 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.0169036 |
| TMEM245 | transmembrane protein 245 | 0.0166201 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.0165815 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GMDS | GDP-mannose 4,6-dehydratase | -0.198607 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.178604 |
| RNF213 | ring finger protein 213 | -0.15301 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.151475 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.146969 |
| LYZ | lysozyme | -0.139199 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.122723 |
| SP100 | SP100 nuclear antigen | -0.119245 |
| RIGI | RNA sensor RIG-I | -0.115181 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.112674 |
| MX1 | MX dynamin-like GTPase 1 | -0.109954 |
| NPSR1 | neuropeptide S receptor 1 | -0.105762 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0884759 |
| ANXA2 | annexin A2 | -0.0836758 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0775114 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0770597 |
| INTS6 | integrator complex subunit 6 | -0.076616 |
| MX2 | MX dynamin-like GTPase 2 | -0.0746871 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0726255 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0723097 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0719463 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0718745 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0712981 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.068604 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0685251 |
| SQSTM1 | sequestosome 1 | -0.0651661 |
| LAMA4 | laminin, alpha 4 | -0.0616739 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.061383 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0612959 |
| PTMA | prothymosin, alpha | -0.0608252 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0599835 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.059697 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0590867 |
| XAF1 | XIAP associated factor 1 | -0.0586517 |
| SPATA13 | spermatogenesis associated 13 | -0.057133 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0565219 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0562987 |
| LMO7 | LIM domain 7 | -0.054365 |
| ITGA6 | integrin, alpha 6 | -0.0537249 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0533597 |
| PRKCA | protein kinase C, alpha | -0.0521811 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0520904 |
| PLSCR2 | phospholipid scramblase 2 | -0.051366 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0508354 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0503821 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0493611 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0481103 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.046715 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0462605 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0459795 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0449603 |
| GOLGB1 | golgin B1 | -0.0449098 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0439851 |
| MECOM | MDS1 and EVI1 complex locus | -0.0439648 |
| IGF1R | insulin-like growth factor 1 receptor | -0.043559 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0434648 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0426328 |
| PMP22 | peripheral myelin protein 22 | -0.0422929 |
| EPHB2 | EPH receptor B2 | -0.0412014 |
| EGR1 | early growth response 1 | -0.0407318 |
| PERP | PERP, TP53 apoptosis effector | -0.0407252 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0405619 |
| ASPH | aspartate beta-hydroxylase | -0.0404688 |
| MCU | mitochondrial calcium uniporter | -0.0403663 |
| SSH2 | slingshot protein phosphatase 2 | -0.039537 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0393407 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | -0.0381531 |
| CANX | calnexin | -0.0381026 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0375116 |
| ADAR | adenosine deaminase, RNA-specific | -0.0371281 |
| RRBP1 | ribosome binding protein 1 | -0.0370699 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0367933 |
| VMP1 | vacuole membrane protein 1 | -0.0367123 |
| ACTG1 | actin gamma 1 | -0.0355896 |
| LAP3 | leucine aminopeptidase 3 | -0.0349579 |
| ATP11A | ATPase, class VI, type 11A | -0.034869 |
| MAP7 | microtubule-associated protein 7 | -0.0348668 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0347518 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0346749 |
| EZR | ezrin | -0.0342219 |
| TJP1 | tight junction protein 1 | -0.0340852 |
| PHF3 | PHD finger protein 3 | -0.0338889 |
| TNS4 | tensin 4 | -0.0338072 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0331347 |
| IRF1 | interferon regulatory factor 1 | -0.0330429 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0328789 |
| MSI2 | musashi RNA-binding protein 2 | -0.0328576 |
| APOL6 | apolipoprotein L, 6 | -0.032021 |
| APP | amyloid beta (A4) precursor protein | -0.0315439 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0308365 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0305907 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0305456 |
| FBXO39 | F-box protein 39 | -0.030281 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | -0.0301519 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0298967 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0298281 |
| SETX | senataxin | -0.0297949 |
| SAMHD1 | SAM domain and HD domain 1 | -0.0297876 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0293663 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0286074 |
