| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ranolazine perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ranolazine_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.158739 |
| CLU | clusterin | 0.11628 |
| FOXO1 | forkhead box O1 | 0.107494 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0997556 |
| EFHD2 | EF-hand domain family, member D2 | 0.0754007 |
| BCL2L1 | BCL2-like 1 | 0.0711425 |
| MYOF | myoferlin | 0.0710548 |
| B2M | beta-2-microglobulin | 0.0646454 |
| POTEF | POTE ankyrin domain family, member F | 0.0577599 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0573506 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0544112 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0544017 |
| SMAD3 | SMAD family member 3 | 0.0528071 |
| RPS21 | ribosomal protein S21 | 0.0522739 |
| SLC45A4 | solute carrier family 45, member 4 | 0.048859 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0481693 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0472486 |
| PLAT | plasminogen activator, tissue | 0.0455847 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0444513 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0434222 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0427361 |
| CUL4B | cullin 4B | 0.0425221 |
| ANKRD33B | ankyrin repeat domain 33B | 0.042213 |
| ITGA6 | integrin, alpha 6 | 0.0415368 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0410772 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0401855 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0401798 |
| MCL1 | myeloid cell leukemia 1 | 0.039402 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0393541 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0384292 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0380109 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0379507 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0372493 |
| CD44 | CD44 molecule (Indian blood group) | 0.0370549 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0356498 |
| TNS4 | tensin 4 | 0.03555 |
| NRG1 | neuregulin 1 | 0.0352632 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.0349999 |
| SEPTIN9 | septin 9 | 0.0343899 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0341278 |
| RNF19B | ring finger protein 19B | 0.0337517 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0336539 |
| LUZP1 | leucine zipper protein 1 | 0.0334454 |
| METTL15 | methyltransferase like 15 | 0.0334335 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0334302 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.033008 |
| PDLIM1 | PDZ and LIM domain 1 | 0.0321867 |
| RNF145 | ring finger protein 145 | 0.0312949 |
| KRT17 | keratin 17, type I | 0.0307738 |
| TPX2 | TPX2, microtubule-associated | 0.0304626 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0301093 |
| RIN2 | Ras and Rab interactor 2 | 0.030107 |
| MSN | moesin | 0.0297733 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0292525 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0289479 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.02843 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0278783 |
| CAPRIN2 | caprin family member 2 | 0.0276196 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | 0.0275403 |
| PKM | pyruvate kinase, muscle | 0.0275343 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0272266 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.02719 |
| RAB10 | RAB10, member RAS oncogene family | 0.0267314 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0264275 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0263521 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.026276 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0261349 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0260717 |
| TMSB10 | thymosin beta 10 | 0.0258298 |
| PLPP1 | phospholipid phosphatase 1 | 0.0257612 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.0257538 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0256757 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0254974 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.025488 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0251158 |
| ARRDC3 | arrestin domain containing 3 | 0.0247373 |
| PCBP2 | poly(rC) binding protein 2 | 0.0246334 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0245678 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0241915 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0240589 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0236967 |
| KIF16B | kinesin family member 16B | 0.0236573 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.0236151 |
| VCL | vinculin | 0.0235697 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0235478 |
| KRT6A | keratin 6A, type II | 0.0235082 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | 0.0234655 |
| PRELID2 | PRELI domain containing 2 | 0.0231543 |
| RPLP2 | ribosomal protein, large, P2 | 0.0230296 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0229738 |
| FNIP1 | folliculin interacting protein 1 | 0.0227416 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0225708 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0223854 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0215684 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0215078 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0214162 |
| IGF2 | insulin-like growth factor 2 | 0.021395 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | 0.021171 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0211065 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0210289 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.150711 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.128549 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.103656 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0865184 |
| RAI14 | retinoic acid induced 14 | -0.0855613 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0855168 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.081328 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0811335 |
| SULF2 | sulfatase 2 | -0.0804722 |
| LMO7 | LIM domain 7 | -0.0795548 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0728754 |
| MTSS1 | metastasis suppressor 1 | -0.0693404 |
| INTS6 | integrator complex subunit 6 | -0.0653301 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0652377 |
| AHNAK | AHNAK nucleoprotein | -0.062566 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0607826 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0605047 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0590053 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0562559 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0561175 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0534554 |
| ASPH | aspartate beta-hydroxylase | -0.0518301 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0514492 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0506486 |
| ANXA1 | annexin A1 | -0.05055 |
| RIGI | RNA sensor RIG-I | -0.0496055 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0492229 |
| NDRG1 | N-myc downstream regulated 1 | -0.0468195 |
| CALB1 | calbindin 1, 28kDa | -0.0463382 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0455268 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0446615 |
| LAMC2 | laminin, gamma 2 | -0.0445979 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0442588 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0437489 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0432539 |
| SQSTM1 | sequestosome 1 | -0.0427566 |
| HMGA2 | high mobility group AT-hook 2 | -0.042388 |
| UTRN | utrophin | -0.0415156 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0409107 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0404306 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0402224 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0400825 |
| HLA-E | major histocompatibility complex, class I, E | -0.0394105 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.038223 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0382166 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0375171 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0372412 |
| CUX1 | cut-like homeobox 1 | -0.0372295 |
| PODXL | podocalyxin-like | -0.0353756 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0353577 |
| EFNA5 | ephrin-A5 | -0.0352579 |
| DOK5 | docking protein 5 | -0.0350881 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0340005 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0338288 |
| EGFR | epidermal growth factor receptor | -0.0331799 |
| CNTNAP3 | contactin associated protein-like 3 | -0.0327251 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0327225 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0326874 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.032532 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0313861 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0313448 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0311846 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.030915 |
| RNF217 | ring finger protein 217 | -0.0304202 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0302804 |
| PRSS23 | protease, serine, 23 | -0.0302641 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0300499 |
| RND3 | Rho family GTPase 3 | -0.0300074 |
| SMYD3 | SET and MYND domain containing 3 | -0.0298874 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0297712 |
| IFI44L | interferon-induced protein 44-like | -0.0287378 |
| NAV2 | neuron navigator 2 | -0.0286398 |
| PLEC | plectin | -0.028152 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0278864 |
| CDK6 | cyclin-dependent kinase 6 | -0.0277912 |
| DST | dystonin | -0.0277889 |
| DENND1A | DENN/MADD domain containing 1A | -0.0268537 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0265059 |
| RAD51B | RAD51 paralog B | -0.0264168 |
| HDAC9 | histone deacetylase 9 | -0.0264102 |
| MTAP | methylthioadenosine phosphorylase | -0.0258552 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0253129 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0251485 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0251334 |
| STC1 | stanniocalcin 1 | -0.0249666 |
| MECOM | MDS1 and EVI1 complex locus | -0.0245493 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.024467 |
| SULF1 | sulfatase 1 | -0.0243329 |
| ENO1 | enolase 1, (alpha) | -0.0237276 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0236341 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0229073 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0228345 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.0228256 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0227495 |
| TNS3 | tensin 3 | -0.0226432 |
| EXOC4 | exocyst complex component 4 | -0.0223977 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0223966 |
| FBXO11 | F-box protein 11 | -0.0221002 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0220954 |
| CANX | calnexin | -0.0219474 |
