| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ranolazine perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ranolazine_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0781649 |
| MT2A | metallothionein 2A | 0.0637958 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0599197 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0490142 |
| RPLP1 | ribosomal protein, large, P1 | 0.0447993 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0442796 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0439854 |
| RNF145 | ring finger protein 145 | 0.0411306 |
| RPL35A | ribosomal protein L35a | 0.0404157 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0391711 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0391641 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0387737 |
| RPLP0 | ribosomal protein, large, P0 | 0.0361506 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0341186 |
| SPAG9 | sperm associated antigen 9 | 0.0339729 |
| TOP1 | topoisomerase (DNA) I | 0.0327151 |
| FTL | ferritin, light polypeptide | 0.0307121 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 0.0301101 |
| RPS8 | ribosomal protein S8 | 0.0300867 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0285302 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0281557 |
| RPL34 | ribosomal protein L34 | 0.027973 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0276247 |
| ABLIM1 | actin binding LIM protein 1 | 0.0273533 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0271508 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0267513 |
| RPS6 | ribosomal protein S6 | 0.026224 |
| CCNH | cyclin H | 0.0254362 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0247957 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0247479 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0247121 |
| TMSB10 | thymosin beta 10 | 0.0247044 |
| RPL11 | ribosomal protein L11 | 0.0241146 |
| RPS25 | ribosomal protein S25 | 0.0231909 |
| RPL30 | ribosomal protein L30 | 0.0229697 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0228684 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.022851 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0226683 |
| SEC61G | Sec61 gamma subunit | 0.0223652 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0217907 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0207893 |
| RPL7 | ribosomal protein L7 | 0.020557 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0203635 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0200775 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.019686 |
| RPL23 | ribosomal protein L23 | 0.0191816 |
| RPL37A | ribosomal protein L37a | 0.0191804 |
| RPS21 | ribosomal protein S21 | 0.0191396 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0189968 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | 0.0189112 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.018909 |
| IRS2 | insulin receptor substrate 2 | 0.0187115 |
| RPL31 | ribosomal protein L31 | 0.0184683 |
| ATP13A3 | ATPase type 13A3 | 0.0181629 |
| KIAA1217 | KIAA1217 | 0.0181126 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0179973 |
| WDR45B | WD repeat domain 45B | 0.0178209 |
| PGK1 | phosphoglycerate kinase 1 | 0.0177 |
| FBXO11 | F-box protein 11 | 0.0175348 |
| RPL37 | ribosomal protein L37 | 0.0175046 |
| SYAP1 | synapse associated protein 1 | 0.0173795 |
| RPS27 | ribosomal protein S27 | 0.0173669 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.017041 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0168461 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0166852 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0164759 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0164601 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0164415 |
| TMEM165 | transmembrane protein 165 | 0.0164055 |
| ANKRD37 | ankyrin repeat domain 37 | 0.0163969 |
| RAP2B | RAP2B, member of RAS oncogene family | 0.01622 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0162058 |
| NPTN | neuroplastin | 0.0161596 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | 0.0160389 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0160059 |
| RPS19 | ribosomal protein S19 | 0.0157667 |
| RPS4X | ribosomal protein S4, X-linked | 0.0157282 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0156725 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0148468 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0145236 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0144879 |
| RPS20 | ribosomal protein S20 | 0.014414 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0143247 |
| MYO1E | myosin IE | 0.0143102 |
| BMP6 | bone morphogenetic protein 6 | 0.0142033 |
| RPS24 | ribosomal protein S24 | 0.0142001 |
| NGLY1 | N-glycanase 1 | 0.0141772 |
| KYNU | kynureninase | 0.0141364 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0140888 |
| RPS23 | ribosomal protein S23 | 0.0140444 |
| NABP1 | nucleic acid binding protein 1 | 0.0140358 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0139938 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0139055 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0137384 |
| RPS14 | ribosomal protein S14 | 0.0137141 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0135227 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0134634 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.0131864 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.0131647 |
| GPATCH2L | G patch domain containing 2-like | 0.0130341 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | -0.238935 |
| EGFR | epidermal growth factor receptor | -0.187426 |
| ASPH | aspartate beta-hydroxylase | -0.168855 |
| NDRG1 | N-myc downstream regulated 1 | -0.119261 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0819903 |
| CES1 | carboxylesterase 1 | -0.0683099 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0673353 |
| LMO7 | LIM domain 7 | -0.066212 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0608364 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0543418 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0488598 |
| HDLBP | high density lipoprotein binding protein | -0.0456833 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0437548 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0412338 |
| SCEL | sciellin | -0.040704 |
| HYOU1 | hypoxia up-regulated 1 | -0.0393882 |
| PKM | pyruvate kinase, muscle | -0.038514 |
| ACTG1 | actin gamma 1 | -0.0384802 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0382925 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0373892 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0367971 |
| GOLGB1 | golgin B1 | -0.0351328 |
| CANX | calnexin | -0.0349634 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0343879 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0337788 |
| CAV2 | caveolin 2 | -0.0329519 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0324519 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0324386 |
| MYOF | myoferlin | -0.0324286 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0322679 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0321061 |
| POTEF | POTE ankyrin domain family, member F | -0.0315725 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0308611 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0295715 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0288939 |
| PLEC | plectin | -0.0282562 |
| CDCP1 | CUB domain containing protein 1 | -0.0275931 |
| RIN2 | Ras and Rab interactor 2 | -0.0275597 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0269959 |
| TPM3 | tropomyosin 3 | -0.0269808 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0265239 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0263245 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0262201 |
| MSN | moesin | -0.0262192 |
| DSPP | dentin sialophosphoprotein | -0.0259333 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0254423 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.025386 |
| ARCN1 | archain 1 | -0.0252846 |
| EZR | ezrin | -0.0250144 |
| FLNB | filamin B, beta | -0.0249639 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0249473 |
| VMP1 | vacuole membrane protein 1 | -0.0248646 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0247919 |
| SUCO | SUN domain containing ossification factor | -0.024513 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0244648 |
| FOXP1 | forkhead box P1 | -0.0242649 |
| ANO6 | anoctamin 6 | -0.023753 |
| STC1 | stanniocalcin 1 | -0.0236994 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.023657 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0236538 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0236377 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0235152 |
| TAOK1 | TAO kinase 1 | -0.0234926 |
| USP34 | ubiquitin specific peptidase 34 | -0.0232466 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0231859 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0230769 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0230687 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0229629 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0229097 |
| APP | amyloid beta (A4) precursor protein | -0.0228914 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0228039 |
| PTK2 | protein tyrosine kinase 2 | -0.0225278 |
| H1-0 | H1.0 linker histone | -0.0224758 |
| KRT7 | keratin 7, type II | -0.0224084 |
| FAT1 | FAT atypical cadherin 1 | -0.0222883 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0222681 |
| CUX1 | cut-like homeobox 1 | -0.0222618 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0219846 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0219197 |
| LRP12 | low density lipoprotein receptor-related protein 12 | -0.0218651 |
| BPTF | bromodomain PHD finger transcription factor | -0.0218499 |
| RPS2 | ribosomal protein S2 | -0.0218388 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0216836 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0215616 |
| CLTC | clathrin, heavy chain (Hc) | -0.0214877 |
| CCND1 | cyclin D1 | -0.0214422 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0214091 |
| BCL9L | B-cell CLL/lymphoma 9-like | -0.0210355 |
| SEC24D | SEC24 family member D | -0.0209959 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0209775 |
| SDC1 | syndecan 1 | -0.0209703 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | -0.0209095 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0208332 |
| CMIP | c-Maf inducing protein | -0.0208198 |
| FRYL | FRY-like | -0.0207483 |
| TMF1 | TATA element modulatory factor 1 | -0.020568 |
| SMAD3 | SMAD family member 3 | -0.0204431 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0203488 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.020344 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0203067 |
