| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ranolazine perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ranolazine_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.200376 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.179455 |
| GRAMD1B | GRAM domain containing 1B | 0.128178 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0868115 |
| RTN4 | reticulon 4 | 0.0822568 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0801515 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0784401 |
| YBX3 | Y box binding protein 3 | 0.0708921 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0707106 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0694917 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0561296 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0538776 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0530714 |
| PHIP | pleckstrin homology domain interacting protein | 0.0501371 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.050004 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0491967 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0491419 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0486553 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | 0.0481369 |
| TPI1 | triosephosphate isomerase 1 | 0.0461938 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.045791 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0455052 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0453126 |
| RNF145 | ring finger protein 145 | 0.0449247 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.044894 |
| OGA | O-GlcNAcase | 0.0444915 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0444455 |
| ANO6 | anoctamin 6 | 0.0429301 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0421498 |
| MKI67 | marker of proliferation Ki-67 | 0.0404376 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0401501 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0389 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0387983 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0375446 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.03707 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0370482 |
| ZFR | zinc finger RNA binding protein | 0.0368836 |
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.0366872 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0366668 |
| PLCB4 | phospholipase C, beta 4 | 0.0355642 |
| CEP192 | centrosomal protein 192kDa | 0.0351539 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0350647 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0346082 |
| TMEM165 | transmembrane protein 165 | 0.0339412 |
| FBXO11 | F-box protein 11 | 0.0337324 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.033479 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0334779 |
| SRPK1 | SRSF protein kinase 1 | 0.0332989 |
| GOLGA4 | golgin A4 | 0.0332226 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0331322 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0328095 |
| MORF4L2 | mortality factor 4 like 2 | 0.0319418 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0315672 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0315494 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0315285 |
| CCND2 | cyclin D2 | 0.0311803 |
| RRM2 | ribonucleotide reductase M2 | 0.0310987 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0309703 |
| BBX | bobby sox homolog (Drosophila) | 0.0307458 |
| SET | SET nuclear proto-oncogene | 0.0307269 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0304307 |
| PCBP2 | poly(rC) binding protein 2 | 0.0301786 |
| RAD51B | RAD51 paralog B | 0.030105 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0300362 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0295483 |
| ZNF292 | zinc finger protein 292 | 0.0293595 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0292523 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0292156 |
| SGO2 | shugoshin 2 | 0.0284379 |
| RASAL2 | RAS protein activator like 2 | 0.0283172 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0281379 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0281284 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0279791 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0278814 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0278378 |
| RASA2 | RAS p21 protein activator 2 | 0.0276996 |
| RPLP0 | ribosomal protein, large, P0 | 0.0276985 |
| TMEM41B | transmembrane protein 41B | 0.0276879 |
| RBM25 | RNA binding motif protein 25 | 0.0276149 |
| XPO1 | exportin 1 | 0.0275917 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0274131 |
| JMJD1C | jumonji domain containing 1C | 0.0272471 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.027228 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.0272216 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0270798 |
| EXOC6B | exocyst complex component 6B | 0.0269357 |
| SRPK2 | SRSF protein kinase 2 | 0.0268801 |
| PDS5A | PDS5 cohesin associated factor A | 0.0266907 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.026636 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0264307 |
| PFDN2 | prefoldin subunit 2 | 0.0260195 |
| IPO7 | importin 7 | 0.0257727 |
| CBX3 | chromobox homolog 3 | 0.0257504 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0257168 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0256361 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0255209 |
| NUP153 | nucleoporin 153kDa | 0.025314 |
| IGF2BP1 | insulin-like growth factor 2 mRNA binding protein 1 | 0.0251866 |
| GATAD2B | GATA zinc finger domain containing 2B | 0.0251013 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0250941 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.192363 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.117273 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0828873 |
| PTMA | prothymosin, alpha | -0.0781829 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0756863 |
| MCL1 | myeloid cell leukemia 1 | -0.0703894 |
| TMSB10 | thymosin beta 10 | -0.0698541 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0611296 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0569539 |
| HLA-B | major histocompatibility complex, class I, B | -0.0429575 |
| CUX1 | cut-like homeobox 1 | -0.0402427 |
| EGR1 | early growth response 1 | -0.0398989 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0385832 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0383167 |
| TPM4 | tropomyosin 4 | -0.037578 |
| AEBP2 | AE binding protein 2 | -0.0369341 |
| INTS6 | integrator complex subunit 6 | -0.0362755 |
| YBX1 | Y box binding protein 1 | -0.0361939 |
| CALR | calreticulin | -0.0324329 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0323964 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0322626 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0321109 |
| ATXN1 | ataxin 1 | -0.0302788 |
| NDRG1 | N-myc downstream regulated 1 | -0.0297275 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0297106 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0296731 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0289918 |
| POTEF | POTE ankyrin domain family, member F | -0.0288939 |
| RPS3 | ribosomal protein S3 | -0.0287796 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0281371 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0278605 |
| RPL35A | ribosomal protein L35a | -0.027272 |
| S100A10 | S100 calcium binding protein A10 | -0.0270655 |
| LRRC23 | leucine rich repeat containing 23 | -0.0261399 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0259024 |
| ACTG1 | actin gamma 1 | -0.0257352 |
| RPS2 | ribosomal protein S2 | -0.0252415 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0252287 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0251201 |
| VCL | vinculin | -0.0251012 |
| TPM3 | tropomyosin 3 | -0.0248953 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0244246 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0240886 |
| VIM | vimentin | -0.0239256 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0234489 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0232106 |
| FTL | ferritin, light polypeptide | -0.0229719 |
| TAPBP | TAP binding protein (tapasin) | -0.0228337 |
| MEF2D | myocyte enhancer factor 2D | -0.0224058 |
| HMGA2 | high mobility group AT-hook 2 | -0.0222839 |
| IER3 | immediate early response 3 | -0.0221256 |
| BRD2 | bromodomain containing 2 | -0.0216476 |
| RYR3 | ryanodine receptor 3 | -0.0212361 |
| RPL37A | ribosomal protein L37a | -0.0205573 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0201729 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0199938 |
| JUN | jun proto-oncogene | -0.0199733 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0199267 |
| STX8 | syntaxin 8 | -0.0194142 |
| RPS19 | ribosomal protein S19 | -0.019203 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | -0.0192 |
| DIAPH2 | diaphanous-related formin 2 | -0.0189712 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.018823 |
| NEK10 | NIMA-related kinase 10 | -0.0186551 |
| HYOU1 | hypoxia up-regulated 1 | -0.0183905 |
| RPS8 | ribosomal protein S8 | -0.0181229 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0181094 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0178338 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0176572 |
| COPA | coatomer protein complex, subunit alpha | -0.0175169 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0172817 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0172619 |
| NTSR1 | neurotensin receptor 1 (high affinity) | -0.0169478 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.016671 |
| VCP | valosin containing protein | -0.0165924 |
| TRIM59 | tripartite motif containing 59 | -0.0163814 |
| BRD4 | bromodomain containing 4 | -0.0163591 |
| RCC1 | regulator of chromosome condensation 1 | -0.0162863 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0161619 |
| RPL8 | ribosomal protein L8 | -0.016077 |
| SFTPA2 | surfactant protein A2 | -0.0160232 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0157542 |
| FN1 | fibronectin 1 | -0.0157506 |
| LOXL2 | lysyl oxidase-like 2 | -0.0157334 |
| HDLBP | high density lipoprotein binding protein | -0.0157118 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0156852 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0154727 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0154446 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0153966 |
| RPLP1 | ribosomal protein, large, P1 | -0.0153476 |
| VEGFA | vascular endothelial growth factor A | -0.0153381 |
| MYOM1 | myomesin 1 | -0.0152177 |
| CAVIN1 | caveolae associated protein 1 | -0.0150514 |
| RPS27A | ribosomal protein S27a | -0.0150194 |
| RPL31 | ribosomal protein L31 | -0.0149161 |
| RPS10 | ribosomal protein S10 | -0.0148789 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0142381 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.014179 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0141782 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0141111 |
