| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ranolazine perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ranolazine_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RNF145 | ring finger protein 145 | 0.0864512 |
| RPS6 | ribosomal protein S6 | 0.0789985 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0776129 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0748257 |
| S100A6 | S100 calcium binding protein A6 | 0.0684573 |
| RPLP0 | ribosomal protein, large, P0 | 0.0670204 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0651694 |
| RPL7 | ribosomal protein L7 | 0.0646594 |
| RPL9 | ribosomal protein L9 | 0.0640788 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0630746 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0630107 |
| RPL35A | ribosomal protein L35a | 0.0597506 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.057814 |
| MT2A | metallothionein 2A | 0.0573425 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0567989 |
| RPL23 | ribosomal protein L23 | 0.0562676 |
| RPS25 | ribosomal protein S25 | 0.0561608 |
| RPS23 | ribosomal protein S23 | 0.0531965 |
| PCBP2 | poly(rC) binding protein 2 | 0.0529779 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0529708 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 0.0529301 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0524437 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0493614 |
| RPS8 | ribosomal protein S8 | 0.0490795 |
| MEF2A | myocyte enhancer factor 2A | 0.0485553 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0463011 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0452464 |
| CD109 | CD109 molecule | 0.0437142 |
| TFG | TRK-fused gene | 0.0432963 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0430832 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0423412 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.042335 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0420337 |
| RPLP1 | ribosomal protein, large, P1 | 0.0418857 |
| RBM25 | RNA binding motif protein 25 | 0.041394 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0408387 |
| NCKAP1 | NCK-associated protein 1 | 0.0401679 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0397041 |
| RPL30 | ribosomal protein L30 | 0.0390005 |
| LDHB | lactate dehydrogenase B | 0.0388654 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0381167 |
| DUSP5 | dual specificity phosphatase 5 | 0.0379935 |
| RPLP2 | ribosomal protein, large, P2 | 0.0378058 |
| RASA2 | RAS p21 protein activator 2 | 0.0370848 |
| LDHA | lactate dehydrogenase A | 0.0368272 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0366617 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.036043 |
| RPL11 | ribosomal protein L11 | 0.0358959 |
| RPS13 | ribosomal protein S13 | 0.0358687 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0357198 |
| FAM13A | family with sequence similarity 13, member A | 0.0355198 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0353887 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0351666 |
| RPS16 | ribosomal protein S16 | 0.0348321 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0347973 |
| NUP58 | nucleoporin 58 | 0.0342776 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0339339 |
| MTMR3 | myotubularin related protein 3 | 0.0339188 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0335618 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0333112 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0332865 |
| RPL32 | ribosomal protein L32 | 0.0323733 |
| KLF6 | Kruppel-like factor 6 | 0.0318245 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0308677 |
| CPNE8 | copine VIII | 0.0308064 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0306676 |
| RPL4 | ribosomal protein L4 | 0.0303374 |
| CDC73 | cell division cycle 73 | 0.030179 |
| RPL37A | ribosomal protein L37a | 0.0300498 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0297163 |
| TOP1 | topoisomerase (DNA) I | 0.0294675 |
| UBC | ubiquitin C | 0.0293218 |
| DUSP10 | dual specificity phosphatase 10 | 0.0291554 |
| RPS19 | ribosomal protein S19 | 0.0290176 |
| PGK1 | phosphoglycerate kinase 1 | 0.0281236 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0276113 |
| RPS27 | ribosomal protein S27 | 0.0274565 |
| ZNF292 | zinc finger protein 292 | 0.0273518 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0273209 |
| TMED10 | transmembrane emp24-like trafficking protein 10 (yeast) | 0.0271768 |
| FCHO2 | FCH domain only 2 | 0.027167 |
| SPAG9 | sperm associated antigen 9 | 0.026432 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0261463 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0261196 |
| RPS14 | ribosomal protein S14 | 0.0259221 |
| PAPOLA | poly(A) polymerase alpha | 0.0257248 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0257026 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0256273 |
| USP15 | ubiquitin specific peptidase 15 | 0.0255229 |
| ATP13A3 | ATPase type 13A3 | 0.02544 |
| CYRIB | CYFIP related Rac1 interactor B | 0.0252701 |
| PARD3 | par-3 family cell polarity regulator | 0.0252253 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0251863 |
| RPS3 | ribosomal protein S3 | 0.0249852 |
| DTNA | dystrobrevin, alpha | 0.0249602 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0248149 |
| RACK1 | receptor for activated C kinase 1 | 0.0246907 |
| CERT1 | ceramide transporter 1 | 0.0244148 |
| IL6ST | interleukin 6 signal transducer | 0.0243983 |
| RPS12 | ribosomal protein S12 | 0.0243472 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.256438 |
| NDRG1 | N-myc downstream regulated 1 | -0.134164 |
| FN1 | fibronectin 1 | -0.127954 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.118481 |
| ASPH | aspartate beta-hydroxylase | -0.104353 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.101613 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0929312 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0875529 |
| LAMC2 | laminin, gamma 2 | -0.0858926 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.08565 |
| ACTG1 | actin gamma 1 | -0.0845585 |
| LMO7 | LIM domain 7 | -0.0761072 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0735475 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0701946 |
| ENO1 | enolase 1, (alpha) | -0.0663752 |
| EFNA5 | ephrin-A5 | -0.0655915 |
| EZR | ezrin | -0.0647214 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0643932 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0636385 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0633914 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.061014 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0580366 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0563395 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0546986 |
| EGR1 | early growth response 1 | -0.0534514 |
| SDC4 | syndecan 4 | -0.0527679 |
| CALR | calreticulin | -0.0517074 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0501204 |
| PLEC | plectin | -0.050033 |
| MAP4 | microtubule-associated protein 4 | -0.0480481 |
| POTEF | POTE ankyrin domain family, member F | -0.0476967 |
| H1-0 | H1.0 linker histone | -0.0460538 |
| FBXO32 | F-box protein 32 | -0.0459505 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.045027 |
| VEGFA | vascular endothelial growth factor A | -0.0439741 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0439465 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0438192 |
| PTMA | prothymosin, alpha | -0.0430857 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0425157 |
| RRBP1 | ribosome binding protein 1 | -0.0413219 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0404451 |
| HDLBP | high density lipoprotein binding protein | -0.0385149 |
| SMAD3 | SMAD family member 3 | -0.0382727 |
| CANX | calnexin | -0.038112 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0380935 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0370267 |
| MX1 | MX dynamin-like GTPase 1 | -0.0369573 |
| SP100 | SP100 nuclear antigen | -0.0363371 |
| MAP1B | microtubule-associated protein 1B | -0.0360982 |
| ATXN1 | ataxin 1 | -0.0353265 |
| TXNIP | thioredoxin interacting protein | -0.0350901 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0348564 |
| TPM4 | tropomyosin 4 | -0.0348267 |
| DSG2 | desmoglein 2 | -0.0346632 |
| NAV2 | neuron navigator 2 | -0.034462 |
| TMSB4X | thymosin beta 4, X-linked | -0.0340668 |
| RNF213 | ring finger protein 213 | -0.0333675 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0327212 |
| ATP11A | ATPase, class VI, type 11A | -0.0325435 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0321575 |
| MX2 | MX dynamin-like GTPase 2 | -0.0318965 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0318411 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.031314 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0313084 |
| FHIT | fragile histidine triad | -0.0312857 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0312512 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0311409 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0302305 |
| SQSTM1 | sequestosome 1 | -0.0296364 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.0292444 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0292375 |
| TAPBP | TAP binding protein (tapasin) | -0.0281525 |
| KIAA1217 | KIAA1217 | -0.0279901 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0279383 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0271956 |
| SMYD3 | SET and MYND domain containing 3 | -0.0268955 |
| NF1 | neurofibromin 1 | -0.0268806 |
| LMNA | lamin A/C | -0.026669 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0265972 |
| KRT19 | keratin 19, type I | -0.0263573 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0261237 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0260776 |
| SVIL | supervillin | -0.0259689 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0257017 |
| LAMA4 | laminin, alpha 4 | -0.0254939 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0254644 |
| LAMB3 | laminin, beta 3 | -0.0253631 |
| FRMD5 | FERM domain containing 5 | -0.0253628 |
| TXNRD1 | thioredoxin reductase 1 | -0.0252842 |
| ANO6 | anoctamin 6 | -0.0251803 |
| MYOF | myoferlin | -0.0249991 |
| F11R | F11 receptor | -0.0249849 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0249824 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.024957 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0249462 |
| RPS2 | ribosomal protein S2 | -0.0249269 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0248194 |
| RBM47 | RNA binding motif protein 47 | -0.0247482 |
| ATF3 | activating transcription factor 3 | -0.0247398 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0244748 |
